Determination of structural and functional overlap/divergence of five proto-type galectins by analysis of the growth-regulatory interaction with ganglioside GM1 in silico and in vitro on human neuroblastoma cells

International Journal of Cancer

Volumn 114, Issue 1, 2005, Pages 46-57

  André, Sabine ^a   Kaltner, Herbert ^a   Lensch, Martin ^a   Russwurm, Roland ^a   Siebert, Hans Christian ^a   Fallsehr, Christine ^b   Tajkhorshid, Emad ^c   Heck, Albert J R ^d   Von Knebel Doeberitz, Magnus ^b   Gabius, Hans Joachim ^a   Kopitz, Juergen ^b  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Apoptosis; Galectin; Ganglioside; Lectin; Neoglycoprotein; Neuroblastoma

Indexed keywords

GALECTIN; GALECTIN 1; GALECTIN 2; GALECTIN 3; GALECTIN 4; GALECTIN 5; GALECTIN 7; GALECTIN CG14; GALECTIN CG16; GANGLIOSIDE GM1; GLYCINE; LEUCINE; LYSINE; PENTASACCHARIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COMPETITIVE INHIBITION; COMPUTER MODEL; CONTROLLED STUDY; DIAGNOSTIC VALUE; GROWTH REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR TRANSPORT; LIGAND BINDING; MATHEMATICAL COMPUTING; NEUROBLASTOMA CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHASE TRANSITION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN INTERACTION; PROTEIN QUATERNARY STRUCTURE; RAT; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; CHICKENS; G(M1) GANGLIOSIDE; GALECTIN 1; GALECTIN 2; GALECTIN 3; GALECTIN 4; GALECTINS; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEUROBLASTOMA; PROTEIN STRUCTURE, QUATERNARY; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; TUMOR CELLS, CULTURED;

EID: 19944431311     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.20699     Document Type: Article

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