Pronociceptive role of dynorphins in uninjured animals: N-ethylmaleimide-induced nociceptive behavior mediated through inhibition of dynorphin degradation

Pain

Volumn 113, Issue 3, 2005, Pages 301-309

  Tan No, Koichi ^a   Takahashi, Hiroaki ^a   Nakagawasai, Osamu ^a   Niijima, Fukie ^a   Sato, Takumi ^b   Satoh, Susumu ^b   Sakurada, Shinobu ^a   Marinova, Zoya ^c   Yakovleva, Tatjana ^c   Bakalkin, Georgy ^c   Terenius, Lars ^c   Tadano, Takeshi ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^b NIHON PHARMACEUTICAL UNIVERSITY   (Japan)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Dynorphins; Intrathecal administration; N ethylmaleimide; N methyl d aspartate receptor ion channel complex; Nociceptive behavior; Prodynorphin knockout mice

Indexed keywords

4 BENZYL ALPHA (4 HYDROXYPHENYL) BETA METHYL 1 PIPERIDINEPROPANOL; AGMATINE; ARCAINE; DIZOCILPINE; DYNORPHIN A; DYNORPHIN B; DYNORPHIN DERIVATIVE; IFENPRODIL; ION CHANNEL; MORPHINE; N ETHYLMALEIMIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NALOXONE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG INHIBITION; DRUG POTENCY; DRUG RESPONSE; MALE; MOLECULAR RECOGNITION; MOUSE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; SPECIES COMPARISON;

AGMATINE; ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BIGUANIDES; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; DYNORPHINS; ENKEPHALINS; ENZYME INHIBITORS; ETHYLMALEIMIDE; EXCITATORY AMINO ACID ANTAGONISTS; IMMUNE SERA; INJECTIONS, SPINAL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MORPHINE; NARCOTICS; PIPERIDINES; PROTEIN PRECURSORS; RECEPTORS, OPIOID; SPINAL CORD; TIME FACTORS;

EID: 19944430625     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2004.11.004     Document Type: Article

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