Cholinergic nicotinic receptor involvement in movement disorders associated with Lewy body diseases. An autoradiography study using [ 125I] α-conotoxinMII in the striatum and thalamus

Experimental Neurology

Volumn 191, Issue 2, 2005, Pages 292-300

  Bohr, I J ^a   Ray, M A ^a   McIntosh, J M ^b   Chalon, S ^c   Guilloteau, D ^c   McKeith, I G ^a   Perry, R H ^a   Clementi, F ^d   Perry, E K ^a   Court, J A ^a   Piggott, M A ^a  

^a NEWCASTLE GENERAL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITÉ DE TOURS   (France)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

Centromedial nucleus; Corpus striatum; Dopamine transporter; Lewy body disease; Neurodegenerative diseases; Nicotinic acetylcholine receptors; Parafascicular nucleus; Parkinson disease; Thalamus ventral lateral

Indexed keywords

ALPHA CONOTOXIN MII; DOPAMINE TRANSPORTER; IODINE 125; NICOTINIC RECEPTOR;

AGE DISTRIBUTION; AGED; ARTICLE; AUTOPSY; AUTORADIOGRAPHY; CAUDATE NUCLEUS; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CORPUS STRIATUM; DEMENTIA; DIFFUSE LEWY BODY DISEASE; EXTRAPYRAMIDAL SYNDROME; FEMALE; HUMAN; HUMAN TISSUE; ISOTOPE LABELING; LIGAND BINDING; MALE; MOTOR DYSFUNCTION; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN BINDING; PUTAMEN; RECEPTOR BINDING; THALAMUS; THALAMUS PARAFASCICULAR NUCLEUS;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AUTORADIOGRAPHY; BINDING, COMPETITIVE; CONOTOXINS; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; FEMALE; HUMANS; IODINE RADIOISOTOPES; LEWY BODY DISEASE; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NEOSTRIATUM; NERVE TISSUE PROTEINS; PARKINSON DISEASE; RECEPTORS, NICOTINIC; THALAMUS;

EID: 19944429861     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.expneurol.2004.10.004     Document Type: Article

References (58)

1. Y. Agid Parkinson's disease: pathophysiology Lancet 337 1991 1321 1324
2. C. Asanuma, W.T. Thatch, and G. Jones Distribution of cerebellar terminations and their relation to other afferent terminations in the ventral lateral thalamic region of the monkey Brain Res. Rev. 5 1983 237 265
3. C. Ballard, I. McKeith, D. Burn, R. Harrison, J. O'Brien, K. Lowery, M. Campbell, R. Perry, and P.G. Ince The UPDRS scale as a means of identifying extrapyramidal signs in patients suffering from dementia with Lewy bodies Neurol. Scand. 96 1997 366 371
4. M. Bentovoglio, and M. Steriade Brainstem diencephalic circuits as a structural substrate of the ascending reticular activation concept M.M.G. Marcia The Diencephalons and Sleep 1990 Raven Press New York
5. C.R. Burkhardt, C.M. Filley, B.K. Kleinschmidt-DeMasters, S. de la Monte, M.D. Norenberg, and S.A. Schneck Diffuse Lewy body disease and progressive dementia Neurology 38 1988 1520 1528
6. G. Cartier, D. Yoshikami, W.R. Gray, S. Luo, B.M. Olivera, and J.M. McIntosh A new alpha-conotoxin which targets a3β2 nicotinic acetylcholine receptors J. Biol. Chem. 271 1996 7522 7528
7. S. Chalon, L. Garreau, P. Emond, L. Zimmer, M.-P. Vilar, J.-C. Besnard, and D. Guilloteau Pharmacological characterization of (E)-N-(3-iodoprop-2-enyl)- 2b-carbomethoxy-3b-(49-methylphenyl)nortropane as a selective and potent inhibitor of the neuronal dopamine transporter J. Pharmacol. Exp. Ther. 291 1999 648 654
8. N. Champtiaux, Z.-Y. Han, A. Bessis, F.M. Rossi, M. Zoll, L. Marubio, J.M. McIntosh, and J.-P. Changeux Distribution and pharmacology of a6-containing nicotinic acetylcholine receptors analysed with mutant mice Eur. J. Neurosci. 22 2002 1206 1217
9. N. Champtiaux, C. Gotti, M. Cordeo-Erasquisin, D.J. David, C. Przybylski, C. Lena, F. Clementi, M. Moretti, F.M. Rossi, N. Le Novere, and J.M. McIntosh Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice J. Neurosci. 23 2003 7820 7829
10. P.J. Corringer, N. Le Novere, and J.P. Changeux Nicotinic receptors at the amino acid level Annu. Rev. Pharmacol. Toxicol. 40 2000 431 458
11. J. Court, D. Spurden, S. Lloyd, I. McKeith, C. Ballard, N. Cairns, R. Kerwin, R. Perry, and E. Perry Neuronal nicotinic receptors in dementia with Lewy bodies and schizophrenia: alpha-bungarotoxin and nicotine binding in the thalamus J. Neurochem. 73 1999 1590 1597
12. J.A. Court, M. Piggot, S. Lloyd, N. Cookson, C. Ballard, L. McKeith, R. Perry, and E. Perry Nicotine binding in human striatum: elevation in schizophrenia and reductions in dementia with Lewy's bodies, Parkinson's disease and Alzheimer's disease and in relation to neuroleptic medication Neroscience 98 2000 79 87
13. 125I]UPH, an epibatidine analog, binds with high affinity to neuronal nicotinic cholinergic receptors Pharmacol. Exp. Ther. 282 1997 445 451
14. J.M. Deniau, H. Kita, and S.T. Kitai Patterns of termination of cerebellar and basal ganglia efferents in the rat thalamus. Strictly segregated and partly overlapping projections Neurosci. Lett. 144 1992 202 206
15. A. Freeman, B. Ciliax, R. Bakay, J. Daley, D. Miller, G. Keating, A. Levey, and D. Rye Nigrostriatal collaterals to thalamus degenerate in parkinsonian animal models Ann. Neurol. 50 2001 321 329
16. C. Gotti, D. Fornasari, and F. Clementi Human neuronal nicotinic receptors Prog. Neurobiol. 53 1997 199 237
17. H.J. Groenewegen, and W. Berensde The specificity of the "nonspecific" midline and intralaminar thalamic nuclei Trends Neurosci. 17 1994 52 57
18. Z.-Z. Guan, A. Norberg, M. Mousavi, J.O. Rinne, and E. Hellstrom-Lindahl Selective changes in the levels of nicotinic acetylcholine receptor protein and corresponding mRNA species in the brains of patients with Parkinson's disease Brain Res. 956 2002 358 366
19. A. Heyman, G. Fillenbaum, and S.S. Mirra Consortium to Establish a Registry for Alzheimer's Disease (CERAD): clinical, neuropsychological, and neuropathological components Aging (Milano) 2 1990 415 424
20. T. Hirai, and E.G. Jones Distribution of tachykinin- and enkephalin-immunoreactive fibres in the human thalamus Brain Res. Rev. 14 1989 35 52
21. M.H. Hoehn, and M.D. Yahr Parkinsonism. Onset, progression, and mortality Neurology 17 1967 427 442
22. P.G. Ince, F.K. McArthur, and E. Bjerntess Neuropathological diagnosis in elderly patients in Oslo: Alzheimer's disease, Lewy body disease, vascular lesions Dementia 6 1995 162 168
23. E.G. Jones The Thalamus 1985 Plenum Press New York
24. J.M. Kulak, T. Nguyen, B. Olivera, and J.M. McIntosh a-Conotoxin MII blocks nicotine-stimulated dopamine release in rat stratal synaptosome J. Neurosci. 17 1997 526 5270
25. J.M. Kulak, J.M. McIntosh, and M. Quik Loss of nicotinic receptors in monkey striatum after 1-methyl-4-phenyl-1,2,3,3-tetrahydropyridine treatment is due to a decline in alpha-conotoxin MII sites Mol. Pharmacol. 61 2001 230 238
26. J.M. Kulak, J. Sum, J.L. Musachio, J.M. McIntosh, and M. Quik 5-IA-85380 binds to alpha-conotoxin MII-sensitive nicotinic acetylcholine receptors (nAchRs) as well as a4β2 subtypes J. Neurochem. 81 2002 403 406
27. A. Kuryatov, F. Olale, J. Cooper, C. Choi, and J. Linstrom Human a6 AChR subtypes: subunit composition, assembly, and pharmacological responses Neuropharmacology 39 2000 2570 2590
28. S.R. Lapper, and J.P. Bolam Input from the frontal cortex and the parafasicular nucleus to cholinergic interneuronsin the dorsal stratum of the rat Neuroscience 51 1992 533 545
29. N. Le Novere, and J.P. Changeux Molecular evolution of the nicotinic acetylcholine receptor: an example of multigene family in excitable cells J. Mol. Evol. 40 1995 155 172
30. I. Litvan, A. MacIntyre, and C.G. Goetz Accuracy of the clinical diagnoses of Lewy bodies disease, Parkinson's disease, and dementia with Lewy bodies: a clinicopathological study Arch. Neurol. 55 1998 969 978
31. R.J. Lukas, J.P. Changeux, N. Le Novere, E.X. Albuquerque, D.J. Balfour, D.K. Berg, D. Bertrand, V.A. Chiappinelli, P.B. Clarke, A.C. Collins, J.A. Dani, S.R. Gradi, K.J. Kellar, J.M. Linstrom, M.J. Marks, M. Quik, P.W. Taylor, and S. Wonnecut International Union of Pharmacology: XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits Pharmacol. Rev. 51 1999 397 401
32. G. Macchi, and E.G. Jones Toward an agreement on terminology of nuclear and subnuclear divisions of the motor thalamus J. Neurosurg. 86 1997 77 92
33. H.D. Mansvelder, and D.S. McGehee Cellular and synaptic mechanisms of nicotine addiction J. Neurobiol. 53 2002 606 617
34. C.M. Martin-Ruiz, M. Piggot, C. Gotti, J. Lindstrom, A.D. Mendelow, M.S. Siddique, R.H. Perry, E.K. Perry, and J.A. Court Alpha and beta nicotinic receptors subunits and synaptophysin in putamen from Parkinson's disease Neuropharmacology 39 2000 2830 2839
35. C. Martin-Ruiz, S. Lawrance, M. Piggot, A. Kuryatov, J. Lindstrom, C. Gotti, M.R. Cookson, R.H. Perry, E. Jaros, E.K. Perry, and J.A. Court Nicotinic receptors in the putamen of patients with dementia with Lewy bodies and Parkinson's disease: relation to changes in a-synuclein expression Neurosci. Lett. 335 2002 134 138
36. 3H]epibatidine Brain Res. 801 1998 143 149
37. D.S. McGehee, and L.W. Role Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons Annu. Rev. Physiol. 57 1995 521 546
38. J.M. McIntosh, A. Santos, and B. Olivera Conus peptides targeted to specific nicotinic acetylcholine receptor subtypes Annu. Rev. Biochem. 98 1999 59 88
39. I.G. McKeith Dementia with Lewy bodies Br. J. Psychol. 180 2002 144 147
40. I.G. McKeith Advances in the diagnosis and treatment of dementia with Lewy bodies. Introduction Dementia Geriatr. Cognit. Disord. 17 Suppl. 1 2004 1 2
41. I.G. McKeith, D. Galasko, K. Kosaka, E.K. Perry, D.W. Dickson, L.A. Hansen, D.P. Salmon, J. Lowe, S.S. Mirra, E. Byrne, G. Lennox, N.P. Qiunn, J.A. Edwarson, P.G. Ince, C. Bergeron, A. Burns, B.L. Miller, S. Lowestone, D. Collerton, E.N. Jansen, C.G. Ballard, R.A. de Vos, G.K. Wilcock, K.A. Jellinger, and R.H. Perry Consenus guidelines for the clinical and pathological diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop Neurology 47 1996 1113 1124
42. A. Morel, M. Magnin, and D. Jeanmonod Multiarchitectonic and stereotactic atlas of the human thalamus J. Comp. Neurol. 387 1997 588 630
43. G. Percheron, C. Francois, J. Talbi, and G. Yelnik Fénelon The primate motor thalamus Brain Res. Rev. 22 1996 93 181
44. R.H. Perry, D. Irving, and G. Blessed Senile dementia of Lewy body type. A clinically and neuropathologicallly distinct form of Lewy body dementia in the elderly J. Neurol. Sci. 95 1990 119 139
45. E.K. Perry, C.M. Morris, J.A. Court, A. Cheng, A.F. Fairbairn, I.G. McKeith, D. Irving, A. Brown, and R.H. Perry Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: possible index of early neuropathology Neuroscience 64 1995 385 395
46. E. Perry, J. Court, R. Goodchild, M. Griffiths, E. Jaros, M. Johnson, S. Lloyd, M. Piggott, D. Spurden, C. Ballard, I. McKeith, and R. Perry Clinical neurochemistry: developments in dementia research based on brain bank material J. Neural Transm. 105 1998 915 933
47. E. Perry, M. Walker, and R. Perry Acetylcholine in mind: a neurotransmitter correlate of consciousness? Trends Neurosci. 22 1999 273 280
48. M.A. Piggott, and E.F. Marshall Neurochemical correlates of pathological and iatrogenic extra-pyramidal symptoms E.K. Perry Dementia with Lewy Bodies-Clinical, Pathological and Treatment Issues 1996 Cambridge Univ. Press Cambridge 449 467
49. M.A. Piggott, E.F. Marshall, N. Thomas, S. Lloyd, J.A. Court, E. Jaros, D. Costa, R.H. Perry, and E.K. Perry Dopaminergic activities in the human striatum: rostrocaudal gradients of uptake sites and of D1 and D2 but not of D3 receptor binding or dopamine Neuroscience 90 1999 433 435
50. S.L. Pimlott, M. Piggott, J. Owens, E. Greally, J. Court, E. Jaros, R. Perry, E. Perry, and D. Wyper Nicotinic acetylcholine receptor distribution in Alzheimer's disease, dementia with Lewy bodies, Parkinson's disease, and vascular dementia: in vitro binding study using 5-[(125)I]-A-85380 Neuropsychopharmacology 29 2004 108 116
51. 125I-alpha-conotoxin MII binding sites to nigrostriatal damage in monkey J. Neurosci. 21 2001 5494 5500
52. M. Quik, J.D. Sum, P. Whiteaker, S.E. McCallum, M.J. Marks, J. Musachio, J.M. McIntosh, A.C. Collins, and S.R. Grady Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice Mol. Pharmacol. 63 2003 1169 1179
53. M. Quik, T. Bordia, L. Formo, and J.M. McIntosh Loss of a-conotoxinMII- and A85380-sensitive nicotinic receptors in Parkinson's disease striatum J. Neurochem. 88 2004 668 679
54. F. Rubboli, J.A. Court, C. Sala, C. Morris, B. Chini, E. Perry, and F. Clementi Distribution of nicotinic receptors in the human hippocampus and thalamus Eur. J. Neurosci. 6 1994 1596 1604
55. K. Semba, and A.C. Fibiger Organization of central cholinergic system Prog. Brain Res. 79 1989
56. D.P. Spurden, J.A. Court, S. Lloyd, A. Oakley, R. Perry, C. Pearson, R.G.L. Pullen, and E.K. Perry Nicotinic receptor distribution in the human thalamus: autoradiographical localization of [3H] nicotine and [125I]alpha-bungarotixin binding J. Chem. Neuroanat. 13 1997 105 113
57. S. Vailati, W. Hanke, A. Bejan, B. Barabino, R. Longhi, B. Balestra, M. Moretti, F. Clementi, and C. Gotti Functional a6-containing nicotinic receptors are present in chick retina Mol. Pharmacol. 56 1999 11 19
58. 125I-alpha-conotoxin MII identifies a novel nicotinic acetylcholine receptor population in mouse brain Mol. Pharmacol. 57 2000 913 925