An orally active adenosine A 1 receptor antagonist, FK838, increases renal excretion and maintains glomerular filtration rate in furosemide-resistant rats

British Journal of Pharmacology

Volumn 139, Issue 8, 2003, Pages 1383-1388

  Schnackenberg, Christine G ^a   Merz, Emily ^a   Brooks, David P ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Adenosine; Diuretic resistance; Excretion; FK838; Furosemide; Hydrochlorothiazide; Kidney; Potassium; Sodium

Indexed keywords

6 OXO 3 (2 PHENYLPYRAZOLO[1,5 A]PYRIDIN 3 YL) 1(6H) PYRIDAZINEBUTYRIC ACID; ADENOSINE A1 RECEPTOR ANTAGONIST; FUROSEMIDE; HYDROCHLOROTHIAZIDE;

ARTICLE; CONTROLLED STUDY; DIURESIS; DRUG RESISTANCE; GLOMERULUS FILTRATION RATE; MALE; MICTURITION; NATRIURESIS; NONHUMAN; POTASSIUM EXCRETION; PRIORITY JOURNAL; RAT; SODIUM EXCRETION; URINARY EXCRETION;

ADMINISTRATION, ORAL; ANIMALS; CHLORIDES; DIURESIS; DIURETICS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FUROSEMIDE; GLOMERULAR FILTRATION RATE; HYDROCHLOROTHIAZIDE; MALE; POTASSIUM; PYRAZOLES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A1; SODIUM;

EID: 0141540439     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705370     Document Type: Article

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