The functional interaction between CD98 and CD147 in regulation of virus-induced cell fusion and osteoclast formation

Medical Microbiology and Immunology

Volumn 193, Issue 4, 2004, Pages 155-162

  Mori, Kouki ^a   Nishimura, Makoto ^a   Tsurudome, Masato ^a   Ito, Morihiro ^a   Nishio, Machiko ^a   Kawano, Mitsuo ^a   Kozuka, Yuuji ^a   Yamashita, Yasufumi ^a   Komada, Hiroshi ^a   Uchida, Atsumasa ^a   Ito, Yasuhiko ^a  

^a MIE UNIVERSITY   (Japan)

Author keywords

CD147; CD98; Cell fusion; FRP 1; HIV

Indexed keywords

ANTIBODY; CD147 ANTIBODY; CD147 ANTIGEN; CD98 ANTIBODY; CD98 ANTIGEN; GLYCOPROTEIN GP 160; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; UNCLASSIFIED DRUG;

ANTIGEN FUNCTION; ARTICLE; CELL AGGLUTINATION; CELL AGGREGATION; CELL FUSION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; LEUKEMIA CELL LINE; MONOCYTE; OSTEOCLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; VIRUS;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD147; ANTIGENS, CD98; CELLS, CULTURED; HIV; HIV ENVELOPE PROTEIN GP160; HUMANS; MEMBRANE FUSION; OSTEOCLASTS; PROTEIN INTERACTION MAPPING;

EID: 19944428118     PISSN: 03008584     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00430-003-0191-0     Document Type: Article

References (38)

1. Berditchevski F, Chang S, Bodorova J, Hemler ME (1997) Generation of monoclonal antibodies to integrin-assocoated proteins: evidence that alpha3beta1 complexes with EMMPRIN/basigin/OX47/M6. J Biol Chem 272:29174-29180
2. Burger KN Verkleij AJ (1990) Membrane fusion. Experientia 46:631-644
3. Cho JK, Fox DA, Horejsi V, Sagawa K, Skubitz KM, Katz DR, Chain B (2001) The functional interactions between CD98, beta1-integrins, and CD147 in the induction of U937 homotypic aggregation. Blood 98:374-382
4. Choe H, Farzan M, Sun Y, Sullivan N, Rollins B, Ponath PD, Wu L, Mackay CR, LaRosa G, Newman W, Gerard N, Gerard C, Sodroski J (1996) The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 85:1135-1148
5. Dalgleish AG, Beverly PCL, Clapham PR, Crawford DH, Greaves MF, Weiss RA (1984) The CD4 (T-4) antigen is an essential component of the receptor for the AIDS retrovirus. Nature 312:763-766
6. Deng H, Liu R, Ellmeier W, Choe S, Unutmaz D, Burkhart M, Di Marzio P, Marmon S, Sutton RE, Hill CM, Davis CB, Peiper SC, Schall TJ, Littman DR, Landau NR (1996) Identification of a major co-receptor for primary isolates of HIV-1. Nature 381:661-666
7. Fadool JM, Linser PJ (1993) 5A11 antigen is a cell recognition molecule which is involved in neuronal-glial interactions in avian neural retina. Dev Dyn 196:252-262
8. Feng Y, Broder CC, Kennedy PE, Berger EA (1996) HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 272:872-877
9. Halestrap AP, Price NT (1999) The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation. Biochem J 343:281-299
10. Higuchi S, Tabata N, Tajima M, Ito M, Tsurudome M, Sudo A, Uchida A, Ito Y (1998) Induction of human osteoclast-like cells by treatment of blood monocytes with anti-fusion regulatory protein-1/CD98 monoclonal antibodies. J Bone Miner Res 13:44-49
11. Higuchi Y, It M, Tajima M, Higuchi S, Miyamoto N, Nishio M, Kawano M, Kusagawa S, Tsurudome M, Sudo A, Kato K, Uchida A, Ito Y (1999) Gene expression during process of osteoclast-like cell formation induced by anti-fusion regulatory protein-1/CD98/4F2 monoclonal antibodies: c-src is selectively induced by anti-FRP-1 mAb. Bone 25:17-24
12. Igakura T, Kadomatsu K, Taguchi O, Muramatsu H, Kaname T, Miyauchi T, Yamamura K, Arimura K, Muramatsu T (1996) Roles of basigin, a member of the immunoglobulin superfamily, in behavior as to an irritating odor, lymphocyte response. Biochem Biophys Res Commun 224:33-36
13. Kasinrerk W, Tokrasinwit N, Phunpae P (1999) CD147 monoclonal antibodies induce homotypic cell aggregation of monocytic cell line U937 via LFA-1/ICAM-1 pathway. Immunology 96:184-192
14. Khunkeawla P, Moonsom S, Straffler G, Kongtawelert P, Kasinrerk W (2001) Engagement of CD147 molecule-induced cell aggregation through the activation of protein kinases and reorganization of the cytoskeleton. Immunobiology 203:659-669
15. Kirk P, Wilson MC, Heddle C, Brown MH, Barclay AN, Halestrap AP (2000) CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression. EMBO J 19:3896-3904
16. Kirsch AH, Diaz LA Jr, Bonish B, Antony PA, Fox DA (1997) The pattern of expression of CD147/neurothelin during human T-cell ontogeny as defined by the monoclonal antibody 8D6. Tissue Antigens 50:147-152
17. Klatzmann D, Champagne E, Chamaret S, Gruest J, Guéstard D, Hercend T, Gluckmann J C, Montagnier L (1984) T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV. Nature 312:767-768
18. Koga Y, Sasaki M, Yoshida H, Wigzell H, Kimura G, Nomoto, K (1990) Cytopathic effect determined by the amount of CD4 molecules in human cell lines expressing envelope glycoprotein of HIV. J Immunol 144: 94-102
19. + cell depletion and progression to AIDS. Ann Intern Med 118:681-688
20. Lifson JD, Feinberg MB, Reyes GR, Rabin L, Banapour B, Chakrabarti S, Moss B, Wong-Staal F, Steimer KS, Engleman EG (1986) Induction of CD4-dependent cell fusion by the HTLV-III/LAV envelope glycoprotein. Nature 323:725-728
21. Lifson JD, Reyes GR, McGrath MS, Stein BS, Engleman EG (1986) AIDS retrovirus induced cytopathology: giant cell formation and involvement of CD4 antigen. Science 232:1123-1127
22. Maddon PJ, Dalgleish AG, McDougal JS, Clapham PR, Weiss RA, Axel R (1988) The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain. Cell 47:333-348
23. McClure MO, Marsh M, Weiss RA (1998) Human immunodeficiency virus infection of CD4-bearing cells occurs by a pH-independent mechanism. EMBO J 7:513-518
24. Namba K, Nishio M, Mori K, Miyamoto N, Tsurudome M, Ito M, Kawano M, Uchida A, Ito Y (2001) Involvement of ADAM9 in multinucleated giant cell formation of blood monocytes. Cell Immunol 213:104-113
25. Ohgimoto, S, Tabata N, Suga S, Nishio M, Ohta H, Tsurudome M, Komada H, Kawano M, Watanabe N, Ito Y (1995) Molecular characterization of fusion regulatory protein-1 (FRP-1) that induces multinucleated giant cell formation of monocytes and HIV gp160-mediated cell fusion. J Immunol 135:3585-3592
26. Ohta, H, Tsurudome M, Matsumura H, Koga Y, Morikawa S, Kawano M, Kusagawa S, Komada H, Nishio M, Ito Y (1994) Molecular and biological characterization of fusion regulatory proteins (FRPs): anti-FRP mAbs induced HIV-mediated cell fusion via an integrin system. EMBO J 13:2044-2055
27. Okamoto K, Tsurudome M, Ohgimoto S, Kawano M, Nishio M, Komada H, Ito M, Sakakura Y, Ito Y (1997) An antifusion regulatory protein-1 monoclonal antibody suppresses human parainfluenza virus type 2-induced cell fusion. J Gen Virol 78:83-89
28. Seulberger H, Lottspeich F, Risau W (1990) The inducible blood-brain barrier specific molecule HT7 is a novel immunoglobulin-like cell surface glycoprotein. EMBO J 9: 2151-2158
29. Sodroski J, Goh WC, Rosen C, Dayton A, Terwilliger E, Haseltine WA (1986) Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity. Nature 322: 470-474
30. Stein BS, Gowda SD, Lifson JD, Penhallow RC, Bensch KG, Engleman EG (1987) pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane. Cell 49:659-668
31. Stonehouse TJ, Woodhead VE, Herridge PS, Ashrafian H, George M, Chain BM, Katz DR (1999) Molecular characterization of U937-dependent T-cell co-stimulation. Immunology 96:35-47
32. Suga K, Katagiri K, Kinashi T, Harazaki M, Iizuka T, Hattori M, Minato N (2001) CD98 induces LFA-1-mediated cell adhesion in lymphoid cells via activation of Rap1. FEBS Lett 489:249-253
33. Suga S, Tsurudome M, Ohgimoto S, Tanata N, Watanabe N, Nishio M, Kawano M, Ito Y (1995) Identification of fusion regulatory protein (FRP)-1/4F2 related molecules: cytoskeletal proteins are associated with FRP-1 molecules that regulate multinucleated giant cell formation of monocytes and HIV-induced cell fusion. Cell Struct Funct 20:473-483
34. Tabata N, Ito M, Shimokata K, Suga S, Ohgimoto S, Tsurudome M, Kawano M, Matsumura H, Komada H, Nishio M, Ito Y (1995) Expression of fusion regulatory proteins (FRPs) on human peripheral blood monocytes. J Immunol 153:3256-3266
35. Tsurudome M, Ito Y (2000) Function of fusion regulatory proteins (FRPs) in immune cells and virus-infected cells. Crit Rev Immunol 20:167-196
36. Tsurudome M, Ito M, Takebayashi S, Okumura K, Nishio M, Kawano M, Kusagawa S, Komada H, Ito Y (1999) Primary structure of the light chain of fusion regulatory protein-1/CD98/4F2 predicts a protein with multiple transmembrane domains that is almost identical to the amino acid transporter E16. J Immunol 162:2462-2466
37. White JM (1990) Viral and cellular membrane fusion protein. Annu Rev Physiol 52:675-697
38. Woodhead VE, Stonehouse TJ, Binks MH, Speide LK, Fox DA, Gaya A, Hardie D, Henniker AJ, Horejsi V, Sagawa K, Skubitz KM, Taskov H, Todd RF 3rd, Agthoven A van, Katz DR, Chain BM (2000) Novel molecular mechanisms of dendritic cell-induced T cell activation. Int Immunol 12:1051-1061