Novel molecular mechanisms of dendritic cell-induced T cell activation

International Immunology

Volumn 12, Issue 7, 2000, Pages 1051-1061

  Woodhead, Vanessa E ^a   Stonehouse, Timothy J ^a   Binks, Michael H ^a   Speidel, Katharina ^a   Fox, David A ^b   Gaya, Antoni ^c   Hardie, Deborah ^d   Henniker, Anthony J ^e   Horejsi, Vaclav ^f   Sagawa, Kimitaka ^g   Skubitz, Keith M ^h   Taskov, Hristo ⁱ   Todd III, Robert F ^j   Van Agthoven, Andre ^k   Katz, David R ^a   Chain, Benjamin M ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c HOSPITAL CLÍNIC   (Spain)

^d UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^e WESTMEAD HOSPITAL   (Australia)

^f INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^g KURUME UNIVERSITY   (Japan)

^h UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

ⁱ NATIONAL CENTER OF INFECTIOUS AND PARASITIC DISEASES   (Bulgaria)

^j UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^k Immunotech   (France)

more..

Author keywords

CD13; CD147; CD148; CD87; CD98; Dendritic cell; T cell activation

Indexed keywords

CD18 ANTIGEN; CD3 ANTIGEN; CELL SURFACE PROTEIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 4; LYMPHOCYTE ANTIBODY; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MICROSOMAL AMINOPEPTIDASE; PROTEIN ANTIBODY;

ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; CELL ADHESION; CELL CULTURE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOMODULATION; LYMPHOCYTE PROLIFERATION; MEMORY CELL; MIXED LYMPHOCYTE REACTION; MOLECULAR RECOGNITION; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

EID: 0033899813     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/12.7.1051     Document Type: Article

References (59)

1. The dendritic cell system and its role in immunogenicity
2. + T cells
3. B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells
4. Intercellular adhesion molecule-2, a second counter-receptor for CD11a/CD18 (leukocyte, function-associated antigen-1), provides a costimulatory signal for T-cell receptor-initiated activation of human T cells
5. Intercellular adhesion molecule-3 is the predominant co-stimulatory ligand for leukocyte function antigen-1 on human blood dendritic cells
6. Human dendritic cells activate T lymphocytes via a CD40:CD40 ligand-dependent pathway
7. CD28/B7 system of T cell costimulation
8. Adhesion receptors involved in clustering of blood dendritic cells and T lymphocytes
9. Clustering of dendritic cells, helper T lymphocytes, and histocompatible B cells during primary antibody responses in vitro
10. Clustering with dendritic cells precedes and is essential for T-cell proliferation in a mitogenesis model
11. Antigen-specific T lymphocytes efficiently cluster with dendritic cells in the human primary mixed-leukocyte reaction
12. + T cells. ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response
13. Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton
14. Human tonsillar dendritic cell-induced T cell responses: Analysis of molecular mechanisms using monoclonal antibodies
15. B70 antigen is a second ligand for CTLA-4 and CD28
16. Activation of human peripheral blood dendritic cells induces the CD86 co-stimulatory molecule
17. Comparative accessory cell function of human peripheral blood dendritic cells and monocytes
18. Immunological heterogeneity of human monocyte subsets prepared by counterflow centrifugation elutriation
19. + peripheral blood monocytes
20. Proliferating dendritic cell progenitors in human blood
21. From sentinel to messenger: An extended phenotypic analysis of the monocyte to dendritic cell transition
22. Epitopemapped mapped monoclonal antibodies as tools for functional and morphological analyses of the human urokinase receptor in tumor tissue
23. Differential expression of urokinase-type plasminogen activator (uPA), its receptor (uPA-R), and inhibitor type-2 (PAI-2) during differentiation of keratinocytes in an organotypic coculture system
24. Phenotypic analysis of functionally associated molecules on peripheral blood and synovial fluid monocytes from arthritis patients
25. Molecular characterisation of U937-dependent T-cell co-stimulation
26. A mouse aminopeptidase N is a marker for antigen-presenting cells and appears to be co-expressed with major histocompatibility complex class II molecules
27. Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes
28. Chemical modification of the urokinase-type plasminogen activator and its receptor using tetranitromethane. Evidence for the involvement of specific tyrosine residues in both molecules during receptor-ligand interaction
29. Physical association of complement receptor type 3 and urokinase-type plasminogen activator receptor in neutrophil membranes
30. The urokinase receptor (CD87) facilities CD11b/CD18-mediated adhesion of human monocytes
31. Mac-1 (CD11b/CD18) and the urokinase receptor (CD87) form a functional unit on monocytic cells
32. Urokinase receptor mediates mechanical force transfer across the cell surface
33. Expression of the human gene encoding urokinase plasminogen activator receptor is activated by disruption of the cytoskeleton
34. Disruption of cytoskeletal structures results in the induction of the urokinase-type plasminogen activator gene expression
35. The urokinase/urokinase-receptor system and cancer invasion
36. Combined overexpression of urokinase, urokinase receptor, and plasminogen activator inhibitor-1 is associated with breast cancer progression: An immunohistochemical comparison of normal, benign, and malignant breast tissues
37. Urokinase plasminogen activator and urokinase plasminogen activator receptor in breast cancer
38. Overexpression of urokinase receptor in breast cancer cells results in increased tumor invasion, growth and metastasis
39. Urokinase receptor. An activation antigen in human T lymphocytes
40. Complementation of dominant suppression implicates CD98 in integrin activation
41. Molecular characterization of fusion regulatory protein-1 (FRP-1) that induces multinucleated giant cell formation of monocytes and HIV gp 160-mediated cell fusion. FRP-1 and 4F2/CD98 are identical molecules
42. Regulation of human immunodeficiency virus gp 160-mediated cell fusion by antibodies against fusion regulatory protein 1
43. CD98: A type II transmembrane glycoprotein expressed from the beginning of primitive and definitive hematopoiesis may play a critical role in the development of hematopoietic cells
44. A novel monoclonal antibody against carbohydrates of L1 cell adhesion molecule causes an influx of calcium in cultured cortical neurons
45. Galectin-3 stimulates uptake of extracellular Ca2+ in human Jurkat T-cells
46. Expression and function of galectin-3, a beta-galactoside-binding lectin, in human monocytes and macrophages
47. Responsiveness of human T lymphocytes to bacterial superantigens presented by cultured rheumatoid arthritis synoviocytes
48. Monocyte-dependent regulation of T lymphocyte activation through CD98
49. + T-helper and a T-killer cell
50. Neurothelin: An inducible cell surface glycoprotein of blood-brain barrier-specific endothelial cells and distinct neurons
51. Neurothelin: Amino acid sequence, cell surface dynamics and actin colocalization
52. Roles of basigin, a member of the immunoglobulin superfamily, in behavior as to an irritating odor, lymphocyte response, and blood-brain barrier
53. CD148 is a membrane protein tyrosine phosphatase present in all hematopoeitic lineages and is involved in signal transduction on lymphocytes
54. Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals
55. The injured cell: The role of the dendritic cell system as a sentinel receptor pathway