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Volumn 8, Issue 1, 2005, Pages 43-52

Fragile X protein functions with Lgl and the PAR complex in flies and mice

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSKELETON PROTEIN; FRAGILE X MENTAL RETARDATION PROTEIN; LETHAL GIANT LARVAE PROTEIN; MESSENGER RNA; PAR PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 19944427334     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2004.10.020     Document Type: Article
Times cited : (64)

References (52)
  • 1
    • 0034936971 scopus 로고    scopus 로고
    • The Drosophila tumor suppressor gene lethal(2)giant larvae is required for the emission of the Decapentaplegic signal
    • Arquier N. Perrin L. Manfruelli P. Semeriva M. The Drosophila tumor suppressor gene lethal(2)giant larvae is required for the emission of the Decapentaplegic signal Development 128 2001 2209-2220
    • (2001) Development , vol.128 , pp. 2209-2220
    • Arquier, N.1    Perrin, L.2    Manfruelli, P.3    Semeriva, M.4
  • 2
    • 0037456795 scopus 로고    scopus 로고
    • The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl
    • Betschinger J. Mechtler K. Knoblich J.A. The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl Nature 422 2003 326-330
    • (2003) Nature , vol.422 , pp. 326-330
    • Betschinger, J.1    Mechtler, K.2    Knoblich, J.A.3
  • 3
    • 0035916321 scopus 로고    scopus 로고
    • Cell polarity: Squaring the circle
    • Bilder D. Cell polarity: Squaring the circle Curr. Biol. 11 2001 R132-R135
    • (2001) Curr. Biol. , vol.11
    • Bilder, D.1
  • 4
    • 4043170088 scopus 로고    scopus 로고
    • Epithelial polarity and proliferation contro: Links from the Drosophila neoplastic tumor suppressors
    • Bilder D. Epithelial polarity and proliferation control: Links from the Drosophila neoplastic tumor suppressors Genes Dev. 18 2004 1909-1925
    • (2004) Genes Dev. , vol.18 , pp. 1909-1925
    • Bilder, D.1
  • 5
    • 0034617129 scopus 로고    scopus 로고
    • Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors
    • Bilder D. Li M. Perrimon N. Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors Science 289 2000 113-116
    • (2000) Science , vol.289 , pp. 113-116
    • Bilder, D.1    Li, M.2    Perrimon, N.3
  • 7
    • 0037164732 scopus 로고    scopus 로고
    • RNA interference: The fragile X syndrome connection
    • Carthew R.W. RNA interference: The fragile X syndrome connection Curr. Biol. 12 2002 R852-R854
    • (2002) Curr. Biol. , vol.12
    • Carthew, R.W.1
  • 9
    • 3042598129 scopus 로고    scopus 로고
    • C. elegans PAR proteins function by mobilizing and stabilizing asymmetrically localized protein complexes
    • Cheeks R.J. Canman J.C. Gabriel W.N. Meyer N. Strome S. Goldstein B. C. elegans PAR proteins function by mobilizing and stabilizing asymmetrically localized protein complexes Curr. Biol. 14 2004 851-862
    • (2004) Curr. Biol. , vol.14 , pp. 851-862
    • Cheeks, R.J.1    Canman, J.C.2    Gabriel, W.N.3    Meyer, N.4    Strome, S.5    Goldstein, B.6
  • 10
    • 0035807836 scopus 로고    scopus 로고
    • Bazooka and atypical protein kinase C are required to regulate oocyte differentiation in the Drosophila ovary
    • Cox D.N. Seyfried S.A. Jan L.Y. Jan Y.N. Bazooka and atypical protein kinase C are required to regulate oocyte differentiation in the Drosophila ovary Proc. Natl. Acad. Sci. USA 98 2001 14475-14480
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 14475-14480
    • Cox, D.N.1    Seyfried, S.A.2    Jan, L.Y.3    Jan, Y.N.4
  • 11
    • 0035900649 scopus 로고    scopus 로고
    • Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function
    • Darnell J.C. Jensen K.B. Jin P. Brown V. Warren S.T. Darnell R.B. Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function Cell 107 2001 489-499
    • (2001) Cell , vol.107 , pp. 489-499
    • Darnell, J.C.1    Jensen, K.B.2    Jin, P.3    Brown, V.4    Warren, S.T.5    Darnell, R.B.6
  • 13
    • 0032588110 scopus 로고    scopus 로고
    • Requirement of Drosophila I(2)gl function for survival of the germline cells and organization of the follicle cells in a columnar epithelium during oogenesis
    • De Lorenzo C. Strand D. Mechler B.M. Requirement of Drosophila I(2)gl function for survival of the germline cells and organization of the follicle cells in a columnar epithelium during oogenesis Int. J. Dev. Biol. 43 1999 207-217
    • (1999) Int. J. Dev. Biol. , vol.43 , pp. 207-217
    • De Lorenzo, C.1    Strand, D.2    Mechler, B.M.3
  • 14
    • 0037071887 scopus 로고    scopus 로고
    • Understanding fragile X syndrome: Insights from retarded flies
    • Gao F.B. Understanding fragile X syndrome: Insights from retarded flies Neuron 34 2002 859-862
    • (2002) Neuron , vol.34 , pp. 859-862
    • Gao, F.B.1
  • 17
    • 0030573007 scopus 로고    scopus 로고
    • Homo-oligomerization domains in the lethal(2)giant larvae tumor suppressor protein, p127 of Drosophila
    • Jakobs R. de Lorenzo C. Spiess E. Strand D. Mechler B.M. Homo-oligomerization domains in the lethal(2)giant larvae tumor suppressor protein, p127 of Drosophila J. Mol. Biol. 264 1996 484-496
    • (1996) J. Mol. Biol. , vol.264 , pp. 484-496
    • Jakobs, R.1    de Lorenzo, C.2    Spiess, E.3    Strand, D.4    Mechler, B.M.5
  • 19
    • 1642276419 scopus 로고    scopus 로고
    • Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice
    • Klezovitch O. Fernandez T.E. Tapscott S.J. Vasioukhin V. Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice Genes Dev. 18 2004 559-571
    • (2004) Genes Dev. , vol.18 , pp. 559-571
    • Klezovitch, O.1    Fernandez, T.E.2    Tapscott, S.J.3    Vasioukhin, V.4
  • 20
    • 0037032804 scopus 로고    scopus 로고
    • Composition and formation of intercellular junctions in epithelial cells
    • Knust E. Bossinger O. Composition and formation of intercellular junctions in epithelial cells Science 298 2002 1955-1999
    • (2002) Science , vol.298 , pp. 1955-1999
    • Knust, E.1    Bossinger, O.2
  • 21
    • 0042009418 scopus 로고    scopus 로고
    • Nuclear translocation of activated MAP kinase is developmentally regulated in the developing Drosophila eye
    • Kumar J.P. Hsiung F. Powers M. Moses K. Nuclear translocation of activated MAP kinase is developmentally regulated in the developing Drosophila eye Development 130 2003 3703-3714
    • (2003) Development , vol.130 , pp. 3703-3714
    • Kumar, J.P.1    Hsiung, F.2    Powers, M.3    Moses, K.4
  • 22
    • 0032509503 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae SOP1 and SOP2 genes, which act in cation homeostasis, can be functionally substituted by the Drosophila lethal(2)giant larvae tumor suppressor gene
    • Larsson K. Bohl F. Sjostrom I. Akhtar N. Strand D. Mechler B.M. Grabowski R. Adler L. The Saccharomyces cerevisiae SOP1 and SOP2 genes, which act in cation homeostasis, can be functionally substituted by the Drosophila lethal(2)giant larvae tumor suppressor gene J. Biol. Chem. 273 1998 33610-33618
    • (1998) J. Biol. Chem. , vol.273 , pp. 33610-33618
    • Larsson, K.1    Bohl, F.2    Sjostrom, I.3    Akhtar, N.4    Strand, D.5    Mechler, B.M.6    Grabowski, R.7    Adler, L.8
  • 23
    • 0345308602 scopus 로고    scopus 로고
    • Control of dendritic development by the Drosophila fragile X-related gene involves the small GTPase Rac1
    • Lee A. Li W. Xu K. Bogert B.A. Su K. Gao F.B. Control of dendritic development by the Drosophila fragile X-related gene involves the small GTPase Rac1 Development 130 2003 5543-5552
    • (2003) Development , vol.130 , pp. 5543-5552
    • Lee, A.1    Li, W.2    Xu, K.3    Bogert, B.A.4    Su, K.5    Gao, F.B.6
  • 24
    • 0033549568 scopus 로고    scopus 로고
    • Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9
    • Lehman K. Rossi G. Adamo J.E. Brennwald P. Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9 J. Cell Biol. 146 1999 125-140
    • (1999) J. Cell Biol. , vol.146 , pp. 125-140
    • Lehman, K.1    Rossi, G.2    Adamo, J.E.3    Brennwald, P.4
  • 25
    • 0030054647 scopus 로고    scopus 로고
    • The tumor suppressor gene, lethal(2)giant larvae (1(2)g1), is required for cell shape change of epithelial cells during Drosophila development
    • Manfruelli P. Arquier N. Hanratty W.P. Semeriva M. The tumor suppressor gene, lethal(2)giant larvae (1(2)g1), is required for cell shape change of epithelial cells during Drosophila development Development 122 1996 2283-2294
    • (1996) Development , vol.122 , pp. 2283-2294
    • Manfruelli, P.1    Arquier, N.2    Hanratty, W.P.3    Semeriva, M.4
  • 27
    • 0037112805 scopus 로고    scopus 로고
    • Trapping of messenger RNA by fragile X mental retardation protein into cytoplasmic granules induces translation repression
    • Mazroui R. Huot M.E. Tremblay S. Filion C. Labelle Y. Khandjian E.W. Trapping of messenger RNA by fragile X mental retardation protein into cytoplasmic granules induces translation repression Hum. Mol. Genet. 11 2002 3007-3017
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 3007-3017
    • Mazroui, R.1    Huot, M.E.2    Tremblay, S.3    Filion, C.4    Labelle, Y.5    Khandjian, E.W.6
  • 28
    • 0035977158 scopus 로고    scopus 로고
    • Microarray analysis and organization of circadian gene expression in Drosophila
    • McDonald M.J. Rosbash M. Microarray analysis and organization of circadian gene expression in Drosophila Cell 107 2001 567-578
    • (2001) Cell , vol.107 , pp. 567-578
    • McDonald, M.J.1    Rosbash, M.2
  • 29
    • 0022083336 scopus 로고
    • Molecular cloning of lethal(2)giant larvae, a recessive oncogene of Drosophila melanogaster
    • Mechler B.M. McGinnis W. Gehring W.J. Molecular cloning of lethal(2)giant larvae, a recessive oncogene of Drosophila melanogaster EMBO J. 4 1985 1551-1557
    • (1985) EMBO J. , vol.4 , pp. 1551-1557
    • Mechler, B.M.1    McGinnis, W.2    Gehring, W.J.3
  • 30
    • 0035879180 scopus 로고    scopus 로고
    • Abnormal development of dendritic spines in fmr1 knock-out mice
    • Nimchinsky E.A. Oberlander A.M. Svoboda K. Abnormal development of dendritic spines in fmr1 knock-out mice J. Neurosci. 21 2001 5139-5146
    • (2001) J. Neurosci. , vol.21 , pp. 5139-5146
    • Nimchinsky, E.A.1    Oberlander, A.M.2    Svoboda, K.3
  • 31
    • 0036301947 scopus 로고    scopus 로고
    • A decade of molecular studies of fragile X syndrome
    • O'Donnell W.T. Warren S.T. A decade of molecular studies of fragile X syndrome Annu. Rev. Neurosci. 25 2002 315-338
    • (2002) Annu. Rev. Neurosci. , vol.25 , pp. 315-338
    • O'Donnell, W.T.1    Warren, S.T.2
  • 32
    • 0037020098 scopus 로고    scopus 로고
    • Identification of mRNA/protein (mRNP) complexes containing Pur-alpha, mStaufen, fragile X protein, and Myosin Va and their association with rough endoplasmic reticulum equipped with a kinesin motor
    • Ohashi S. Koike K. Omori A. Ichinose S. Ohara S. Kobayashi S. Sato T.A. Anzai K. Identification of mRNA/protein (mRNP) complexes containing Pur-alpha, mStaufen, fragile X protein, and Myosin Va and their association with rough endoplasmic reticulum equipped with a kinesin motor J. Biol. Chem. 277 2002 37804-37810
    • (2002) J. Biol. Chem. , vol.277 , pp. 37804-37810
    • Ohashi, S.1    Koike, K.2    Omori, A.3    Ichinose, S.4    Ohara, S.5    Kobayashi, S.6    Sato, T.A.7    Anzai, K.8
  • 33
    • 0035479930 scopus 로고    scopus 로고
    • Intercellular junctions and cellular polarity: The PAR-aPKC complex, a conserved core cassette playing fundamental roles in cell polarity
    • Ohno S. Intercellular junctions and cellular polarity: The PAR-aPKC complex, a conserved core cassette playing fundamental roles in cell polarity Curr. Opin. Cell Biol. 13 2001 641-648
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 641-648
    • Ohno, S.1
  • 34
    • 0034735789 scopus 로고    scopus 로고
    • Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast
    • Ohshiro T. Yagami T. Zhang C. Matsuzaki F. Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast Nature 408 2000 593-596
    • (2000) Nature , vol.408 , pp. 593-596
    • Ohshiro, T.1    Yagami, T.2    Zhang, C.3    Matsuzaki, F.4
  • 35
    • 0034735753 scopus 로고    scopus 로고
    • The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts
    • Peng C.Y. Manning L. Albertson R. Doe C.Q. The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts Nature 408 2000 596-600
    • (2000) Nature , vol.408 , pp. 596-600
    • Peng, C.Y.1    Manning, L.2    Albertson, R.3    Doe, C.Q.4
  • 37
    • 0031036380 scopus 로고    scopus 로고
    • Characterization of a CNS cell line, CAD, in which morphological differentiation is initiated by serum deprivation
    • Qi Y. Wang J.K. McMillian M. Chikaraishi D.M. Characterization of a CNS cell line, CAD, in which morphological differentiation is initiated by serum deprivation J. Neurosci. 17 1997 1217-1225
    • (1997) J. Neurosci. , vol.17 , pp. 1217-1225
    • Qi, Y.1    Wang, J.K.2    McMillian, M.3    Chikaraishi, D.M.4
  • 38
    • 0034666128 scopus 로고    scopus 로고
    • Integrin-mediated regulation of synaptic morphology, transmission and plasticity
    • Rohrbaugh J. Grotewiel M.S. Davis R.L. Broadie K. Integrin-mediated regulation of synaptic morphology, transmission and plasticity J. Neurosci. 20 2000 6868-6878
    • (2000) J. Neurosci. , vol.20 , pp. 6868-6878
    • Rohrbaugh, J.1    Grotewiel, M.S.2    Davis, R.L.3    Broadie, K.4
  • 39
    • 2442477424 scopus 로고    scopus 로고
    • New synaptic bouton formation is disrupted by misregulation of microtubule stability in aPKC mutants
    • Ruiz-Canada C. Ashley J. Moeckel-Cole S. Drier E. Yin J. Budnik V. New synaptic bouton formation is disrupted by misregulation of microtubule stability in aPKC mutants Neuron 42 2004 567-580
    • (2004) Neuron , vol.42 , pp. 567-580
    • Ruiz-Canada, C.1    Ashley, J.2    Moeckel-Cole, S.3    Drier, E.4    Yin, J.5    Budnik, V.6
  • 40
    • 0742323015 scopus 로고    scopus 로고
    • The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation
    • Salazar G. Love R. Werner E. Doucette M.M. Cheng S. Levey A. Faundez V. The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation Mol. Biol. Cell 15 2004 575-587
    • (2004) Mol. Biol. Cell , vol.15 , pp. 575-587
    • Salazar, G.1    Love, R.2    Werner, E.3    Doucette, M.M.4    Cheng, S.5    Levey, A.6    Faundez, V.7
  • 41
    • 0037523396 scopus 로고    scopus 로고
    • CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein
    • Schenck A. Bardoni B. Langmann C. Harden N. Mandel J.L. Giangrande A. CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein Neuron 38 2003 887-898
    • (2003) Neuron , vol.38 , pp. 887-898
    • Schenck, A.1    Bardoni, B.2    Langmann, C.3    Harden, N.4    Mandel, J.L.5    Giangrande, A.6
  • 42
    • 0036892046 scopus 로고    scopus 로고
    • Casein kinase II phosphorylates the fragile X mental retardation protein and modulates its biological properties
    • Siomi M.C. Higashijima K. Ishizuka A. Siomi H. Casein kinase II phosphorylates the fragile X mental retardation protein and modulates its biological properties Mol. Cell. Biol. 22 2002 8438-8447
    • (2002) Mol. Cell Biol. , vol.22 , pp. 8438-8447
    • Siomi, M.C.1    Higashijima, K.2    Ishizuka, A.3    Siomi, H.4
  • 43
    • 0034645066 scopus 로고    scopus 로고
    • Lava lamp, a novel peripheral golgi protein, is required for Drosophila melanogaster cellularization
    • Sisson J.C. Field C. Ventura R. Royou A. Sullivan W. Lava lamp, a novel peripheral golgi protein, is required for Drosophila melanogaster cellularization J. Cell Biol. 151 2000 905-918
    • (2000) J. Cell Biol. , vol.151 , pp. 905-918
    • Sisson, J.C.1    Field, C.2    Ventura, R.3    Royou, A.4    Sullivan, W.5
  • 44
    • 4143119015 scopus 로고    scopus 로고
    • DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila
    • Sotillos S. Diaz-Meco M.T. Caminero E. Moscat J. Campuzano S. DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila J. Cell Biol. 166 2004 549-557
    • (2004) J. Cell Biol. , vol.166 , pp. 549-557
    • Sotillos, S.1    Diaz-Meco, M.T.2    Caminero, E.3    Moscat, J.4    Campuzano, S.5
  • 45
    • 0028061614 scopus 로고
    • The Drosophila lethal(2)giant larvae tumor suppressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain
    • Strand D. Jakobs R. Merdes G. Neumann B. Kalmes A. Heid H.W. Husmann I. Mechler B.M. The Drosophila lethal(2)giant larvae tumor suppressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain J. Cell Biol. 127 1994 1361-1373
    • (1994) J. Cell Biol. , vol.127 , pp. 1361-1373
    • Strand, D.1    Jakobs, R.2    Merdes, G.3    Neumann, B.4    Kalmes, A.5    Heid, H.W.6    Husmann, I.7    Mechler, B.M.8
  • 46
    • 0028051486 scopus 로고
    • The Drosophila lethal(2)giant larvae tumor suppressor protein is a component of the cytoskeleton
    • Strand D. Raska I. Mechler B.M. The Drosophila lethal(2)giant larvae tumor suppressor protein is a component of the cytoskeleton J. Cell Biol. 127 1994 1345-1360
    • (1994) J. Cell Biol. , vol.127 , pp. 1345-1360
    • Strand, D.1    Raska, I.2    Mechler, B.M.3
  • 47
    • 0035674837 scopus 로고    scopus 로고
    • Epithelial cell polarity and cell junctions in Drosophila
    • Tepass U. Tanentzapf G. Ward R. Fehon R. Epithelial cell polarity and cell junctions in Drosophila Annu. Rev. Genet. 35 2001 747-784
    • (2001) Annu. Rev. Genet. , vol.35 , pp. 747-784
    • Tepass, U.1    Tanentzapf, G.2    Ward, R.3    Fehon, R.4
  • 48
    • 0033761489 scopus 로고    scopus 로고
    • Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein
    • Wan L. Dockendorff T.C. Jongens T.A. Dreyfuss G. Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein Mol. Cell. Biol. 20 2000 8536-8547
    • (2000) Mol. Cell Biol. , vol.20 , pp. 8536-8547
    • Wan, L.1    Dockendorff, T.C.2    Jongens, T.A.3    Dreyfuss, G.4
  • 49
    • 0034683578 scopus 로고    scopus 로고
    • Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts
    • Wodarz A. Ramrath A. Grimm A. Knust E. Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts J. Cell Biol. 150 2000 1361-1374
    • (2000) J. Cell Biol. , vol.150 , pp. 1361-1374
    • Wodarz, A.1    Ramrath, A.2    Grimm, A.3    Knust, E.4
  • 50
    • 0032880801 scopus 로고    scopus 로고
    • Apical spectrin is essential for epithelial morphogenesis but not apicobasal polarity in Drosophila
    • Zarnescu D.C. Thomas G.H. Apical spectrin is essential for epithelial morphogenesis but not apicobasal polarity in Drosophila J. Cell Biol. 146 1999 1075-1086
    • (1999) J. Cell Biol. , vol.146 , pp. 1075-1086
    • Zarnescu, D.C.1    Thomas, G.H.2
  • 51
  • 52
    • 0028281387 scopus 로고
    • Paralysis and early death in cysteine string protein mutants of Drosophila
    • Zinsmaier K.E. Eberle K.K. Buchner E. Walter N. Benzer S. Paralysis and early death in cysteine string protein mutants of Drosophila Science 263 1994 977-980
    • (1994) Science , vol.263 , pp. 977-980
    • Zinsmaier, K.E.1    Eberle, K.K.2    Buchner, E.3    Walter, N.4    Benzer, S.5


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