Distribution of Helicobacter pylori cagA, cagE and vacA in different ethnic groups in Kuala Lumpur, Malaysia

Journal of Gastroenterology and Hepatology (Australia)

Volumn 20, Issue 4, 2005, Pages 589-594

  Tan, Huck Joo ^a,d   Rizal, Abdul Manaf ^b   Rosmadi, Mohamed Yusoff ^b   Goh, Khean Lee ^c  

^a Sunway Medical Centre   (Malaysia)

^b UNIVERSITI KEBANGSAAN MALAYSIA   (Malaysia)

^c UNIVERSITY MALAYA MEDICAL CENTRE   (Malaysia)

^d Sunway Medical Centre   (Malaysia)

Author keywords

Different races; Helicobacter pylori genotypes; Virulence factors

Indexed keywords

GENOMIC DNA;

ADULT; ARTICLE; BACTERIAL VIRULENCE; BACTERIUM CULTURE; CAGA GENE; CAGE GENE; CONTROLLED STUDY; ETHNIC GROUP; FEMALE; GASTRITIS; GENE; GENOTYPE; HELICOBACTER PYLORI; HUMAN; MAJOR CLINICAL STUDY; MALAYSIA; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIC ULCER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; VACA GENE;

EID: 19944400433     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2005.03783.x     Document Type: Article

References (30)

1. Marshall B. Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet 1983; 1: 1273-5.
2. Wotherspoon A, Ortiz-Hidalgo O, Falzon M et al. Helicobacter pylori associated gastritis and primary B-cell gastric lymphoma. Lancet 1991; 338: 1175-6.
3. Parsonnet J, Friedman G, Vandersteen D et al. Helicobacter pylori infection and the risk of gastric carcinoma. N. Engl. J. Med. 1991; 325: 1127-31.
4. Van Doom LJ, Figueiredo C, Sanna R et al. Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori. Gastroenterology 1998; 115: 58-66.
5. Atherton JC. The clinical relevance of strain types of Helicobacter pylori. Gut 1997; 40: 701-3.
6. Censini S, Lange C, Xiang Z et al. Cag, a pathogenicity island of Helicobacter pylori, encodes type 1-specific and disease associated virulence factors. Proc. Natl. Acad. Sci. USA 1996; 93: 14 648-53.
7. Beales IL, Crabtree JE, Scunes D, Covacci A, Calam J. Antibodies to cagA protein are associated with gastric atrophy in Helicobacter pylori infection. Eur. J. Gastroenterol. Hepatol. 1996; 8: 645-9.
8. Blaser MJ, Perez-Perez GI, Kleanthous H et al. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res. 1995; 55: 2111-15.
9. Crabtree JE, Farmery SM, Lindley IKD et al. CagA/cytotoxic strains of Helicobacter pylori and interleukin-8 in gastric epithelial cell lines. J. Clin. Pathol. 1994; 47: 945-50.
10. Crabtree JE, Covacci A, Farmery SM et al. Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype. J. Clin. Pathol. 1995; 48: 41-5.
11. Sharma SA, Tummuru MK, Miller GG et al. Interleukin-8 response of gastric epithelial cell lines to Helicobacter pylori stimulation in vitro. Infect. Immun. 1994; 63: 1681-7.
12. Van Doom LJ, Figueiredo C, Rossau R et al. Expanding allelic diversity of Helicobacter pylori vacA. J. Clin. Microbiol. 1998; 36: 2587-603.
13. Atherton JC, Cao P, Peek RMJ et al. Mosacism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration. J. Biol. Chem. 1995; 270: 17 771-7.
14. Odenbreit S, Puls S, Sedlmaier B et al. Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion. Science 2000; 287: 1497-500.
15. Fallone CA, Beech R, Barkun A et al. The Helicobacter pylori vacA S1 genotype and the cagE gene are associated with gastroduodenal disease. Gut 1998; 43 (Suppl.): 19A.
16. Van Doom LJ, Figueiredo C, Megraud F et al. Geographic distribution of vacA allelic types of Helicobacter pylori. Gastroenterology 1999; 116: 823-30.
17. Yamaoka Y, Kodama T, Gutierrez O et al. Relationship between Helicobacter pylori iceA, cagA and vacA status and clinical outcome: studies in four different countries. J. Clin. Microbiol. 1999; 37: 2274-9.
18. Maeda S, Ogura K, Yoshida H et al. Major virulence factors, vacA and cagA, are commonly positive in Helicobacter pylori isolates in Japan. Gut 1998; 42: 338-43.
19. Yamaoka Y, Malaty HM, Osato MS, Graham DY. Conservation of Helicobacter pylori genotypes in different ethnic groups in Houston, Texas. J. Infect. Dis. 2000; 181: 2083-6.
20. Wong BCY, Yin Y, Berg DE et al. Distribution of distinct vacA, cagA and iceA alleles in Helicobacter pylori in Hong Kong. Helicobacter 2001; 6: 317-24.
21. Zheng PY, Hua J, Yeoh KG, Ho B. Association of peptic ulcer with increased expression of Lewis antigens but not cagA, iceA and vacA in Helicobacter pylori isolates in an Asian population. Gut 2000; 47: 18-22.
22. Chattopadhyay S, Datta S, Chowdhury A et al. Virulence genes in Helicobacter pylori strains from West Bengal residents with overt H. pylori-associated disease and healthy volunteers. J. Clin. Microbiol. 2002; 40: 2622-5.
23. Ahuja V, Arur S, Das B, Sharma M. Genotype of Helicobacter pylori does not influence the success rate of eradication therapy in peptic ulcer disease. J. Gastroenterol. Hepatol. 2002; 17 (Suppl.): A22.
24. Lin CW, Wu SC, Lee SC, Cheng KS. Genetic analysis and clinical evaluation of vacuolating cytotoxin gene A and cytotoxin associated gene A in Taiwanese Helicobacter pylori isolates from peptic ulcer patients. Scand. J. Infect. Dis. 2000; 32: 51-7.
25. Pan ZJ, Berg DE, van de Hurst RW et al Prevalence of vacuolating cytotoxin production and distribution of distinct vacA alleles in Helicobacter pylori from China. J. Infect. Dis. 1998; 178: 220-26.
26. Miehlke S, Kirsch C, Agha-Amiri K et al. The Helicobacter pylori vacA S1, m1 genotype and cagA is associated with gastric carcinoma in Germany. Int. J. Cancer 2000; 87: 322-7.
27. Day AS, Jones NL, Lynett JT et al. CagE is a virulence factor associated with Helicobacter pylori-induced duodenal ulceration in children. J. Infect. Dis. 2000; 181: 1370-75.
28. Hsu PI, Hwang I, Cittelly D et al. Clinical presentation in relation to diversity within the Helicobacter pylori cag pathogenicity island. Am. J. Gastroenterol. 2002; 97: 2231-8.
29. Jenks PJ, Megraud F, Labigne A. Clinical outcome after infection with Helicobacter pylori does not appear to be reliably predicted by the presence of any of the genes of the cag pathogenicity island. Gut 1998; 43: 752-8.
30. Sadakane Y, Kusaba K, Nagasawa Z et al. Prevalence and genetic diversity of cagD, cagE and vacA in Helicobacter pylori strains isolated from Japanese patients. Scand. J. Gastroenterol. 1999; 10: 981-6.