Prevalence of vacuolating cytotoxin production and distribution of distinct vacA alleles in Helicobacter pylori from China

Journal of Infectious Diseases

Volumn 178, Issue 1, 1998, Pages 220-226

  Pan, Zhi Jun ^a   Berg, Douglas E ^b   Van Der Hulst, René W M ^b   Su, Wan Wen ^b   Raudonikiene, Ausra ^b   Xiao, Shu Dong ^b   Dankert, Jacob ^b   Tytgat, Guido N J ^b   Van Der Ende, Arie ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIN; SIGNAL PEPTIDE;

ALLELE; ARTICLE; CELL VACUOLE; CHINA; DISEASE ASSOCIATION; DNA SEQUENCE; GASTRITIS; GENE POOL; HELICOBACTER PYLORI; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIC ULCER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STRAIN DIFFERENCE;

HELICOBACTER PYLORI;

EID: 0031868613     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/515601     Document Type: Article

References (21)

1. van der Hulst RWM, Tytgat GNJ. Helicobacter pylori and peptic ulcer disease. Scand J Gastroenterol Suppl 1996;220:10-8.
2. Foreman D, Eurogast Study Group. An international association between Helicobacter pylori infection and gastric cancer. Lancet 1993;341:359-62.
3. Akopyants N, Bukanov NO, Westblom TU, Kresovich S, Berg DE. DNA diversity among clinical isolates of Helicobacter pylori detected by PCR-based RAPD fingerprinting. Nucleic Acids Res 1992;20:5137-42.
4. Jiang Q, Hiratsuka K, Taylor DE. Variability of gene order in different Helicobacter pylori strains contributes to genome diversity. Mol Microbiol 1996;20:833-42.
5. Van der Ende A, Rauws EAJ, Feller M, Mulder CJJ, Tytgat GNJ, Dankert J. Heterogeneous Helicobacter pylori isolates from members of a family with a history of peptic ulcer disease. Gastroenterology 1996;111:638-47.
6. Cover TL, Berg DE, Blaser MJ. VacA and the cag pathogenicity island of H. pylori. In: Ernst PB, Michetti P, Smith PD, eds. The immunobiology of H. pylori: from pathogenesis to prevention. Philadelphia: Lippincott-Raven, 1997:75-90.
7. Figura N, Guglielmetti P, Rossolini A, et al. Cytotoxin production by Campylobacter pylori strain isolated from patients with peptic ulcers and from patients with chronic gastritis only. J Clin Microbiol 1989;27:225-6.
8. Tee W, Lambert JR, Dwyer B. Cytotoxin production by Helicobacter pylori from patients with upper gastrointestinal tract disease. J Clin Microbiol 1995;33:1203-5.
9. Weel JFL, van der Hulst RMW, Gerrits Y, et al. The interrelationship between cytotoxin-associated gene A, vacuolating cytotoxin, and Helicobacter pylori-related diseases. J Infect Dis 1996;173:1171-5.
10. Telford JL, Ghiara P, Dell'Orco M, et al. Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease. J Exp Med 1994;79:1653-8.
11. Cover TL, Tummuru MKR, Cao P, Thompson SA, Blaser MJ. Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains. J Biol Chem 1994;269:10566-73.
12. Atherton JC, Cao P, Peek RM, Tummuru MKR, Blaser MJ, Cover TL. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. J Biol Chem 1995;270:17771-7.
13. Atherton JC, Peek RM, Tham KT, Cover TL, Blaser MJ. Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori. Gastroenterology 1997;112:92-9.
14. Censini S, Lange C, Xiang Z, et al. cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease associated virulence factors. Proc Natl Acad Sci USA 1996;93:14648-53.
15. Akopyants NS, Clifton SW, Kersulyte D, et al. Analyses of the cag pathogenicity island of Helicobacter pylori. Mol Microbiol 1998;28:37-53.
16. Pan ZJ, van der Hulst RWM, Feller M, et al. Equally high prevalences of infection with cagA-positive Helicobacter pylori in Chinese patients with peptic ulcer disease and those with chronic gastritis-associated dyspepsia. J Clin Microbiol 1997;35:1344-7.
17. Leunk RD, Johnson PT, David BC, Kraft WG, Morgan DR. Cytotoxic activity in broth-culture filtrates of Campylobacter pylori. J Med Microbiol 1988;26:93-9.
18. Catrenich CE, Chestnut MH. Character and origin of vacuoles induced in mammalian cells by the cytotoxin of Helicobacter pylori. J Med Microbiol 1992;37:389-95.
19. Ewald PW. Evolution of infectious disease. New York: Oxford, 1994.
20. Ito Y, Azuma T, Ito S, et al. Analysis and typing of the vacA gene from cagA-positive strains of Helicobacter pylori isolated in Japan. J Clin Microbiol 1997;35:1710-4.
21. Ito S, Azuma T, Murakita H, et al. Profile of Helicobacter pylori cytotoxin derived from two areas of Japan with different prevalence of atrophic gastritis. Gut 1996;39:800-6.