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Volumn 37, Issue 2, 2005, Pages 72-82

Effect of steroidal and non-steroidal drugs on the microglia activation pattern and the course of degeneration in the retinal degeneration slow mouse

Author keywords

Acetylsalicylate; Bystander damage; Microglia; Neuroprotection; Neurotoxicity; Prednisolone; Retinal degeneration

Indexed keywords

ACETYLSALICYLIC ACID; ANTIINFLAMMATORY AGENT; CASPASE 3; ENZYME ANTIBODY; NONSTEROID ANTIINFLAMMATORY AGENT; PREDNISOLONE; STEROID; CASP3 PROTEIN, MOUSE; CASPASE; DIFFERENTIATION ANTIGEN; GLUCOCORTICOID; MONOCYTE MACROPHAGE DIFFERENTIATION ANTIGEN; MONOCYTE-MACROPHAGE DIFFERENTIATION ANTIGEN;

EID: 19644393698     PISSN: 00303747     EISSN: None     Source Type: Journal    
DOI: 10.1159/000084248     Document Type: Article
Times cited : (8)

References (61)
  • 1
    • 0031966320 scopus 로고    scopus 로고
    • Mechanisms of cell death in the inherited retinal degenerations
    • Travis GH: Mechanisms of cell death in the inherited retinal degenerations. Am J Hum Genet 1998;62:503-508.
    • (1998) Am J Hum Genet , vol.62 , pp. 503-508
    • Travis, G.H.1
  • 2
    • 0021231752 scopus 로고
    • Development and degeneration of retina in rds mutant mice: Light and electron microscopic observations in experimental chimaeras
    • Sanyal S, Zeilmaker GH: Development and degeneration of retina in rds mutant mice: Light and electron microscopic observations in experimental chimaeras. Exp Eye Res 1984;39: 231-246.
    • (1984) Exp Eye Res , vol.39 , pp. 231-246
    • Sanyal, S.1    Zeilmaker, G.H.2
  • 3
    • 0027260657 scopus 로고
    • Cellular interactions implicated in the mechanism of photoreceptor degeneration in transgenic mice expressing a mutant rhodopsin gene
    • Huang PC, Gaitan AE, Hao Y, Petters RM, Wong F: Cellular interactions implicated in the mechanism of photoreceptor degeneration in transgenic mice expressing a mutant rhodopsin gene. Proc Natl Acad Sci USA 1993;90:8484-8488.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8484-8488
    • Huang, P.C.1    Gaitan, A.E.2    Hao, Y.3    Petters, R.M.4    Wong, F.5
  • 4
    • 0032101737 scopus 로고    scopus 로고
    • Non-cell-autonomous photoreceptor degeneration in rds mutant mice mosaic for expression of a rescue transgene
    • Kedzierski W, Bok D, Travis GH: Non-cell-autonomous photoreceptor degeneration in rds mutant mice mosaic for expression of a rescue transgene. J Neurosci 1998;18:4076-4082.
    • (1998) J Neurosci , vol.18 , pp. 4076-4082
    • Kedzierski, W.1    Bok, D.2    Travis, G.H.3
  • 6
    • 0029347050 scopus 로고
    • Human retinal microglia: Expression of immune markers and relationship to the glia limitans
    • Provis JM, Penfold PL, Edwards AJ, van Driel D: Human retinal microglia: Expression of immune markers and relationship to the glia limitans. Glia 1995;14:243-256.
    • (1995) Glia , vol.14 , pp. 243-256
    • Provis, J.M.1    Penfold, P.L.2    Edwards, A.J.3    Van Driel, D.4
  • 7
    • 0030860260 scopus 로고    scopus 로고
    • Soluble macrophage factors trigger apoptosis in cultured hippocampal neurons
    • Flavin MP, Coughlin K, Ho LT: Soluble macrophage factors trigger apoptosis in cultured hippocampal neurons. Neuroscience 1997;80: 437-448.
    • (1997) Neuroscience , vol.80 , pp. 437-448
    • Flavin, M.P.1    Coughlin, K.2    Ho, L.T.3
  • 11
    • 0030027848 scopus 로고    scopus 로고
    • Microglial cells invade the outer retina as photoreceptors degenerate in Royal College of Surgeons rats
    • Roque RS, Imperial CJ, Caldwell RB: Microglial cells invade the outer retina as photoreceptors degenerate in Royal College of Surgeons rats. Invest Ophthalmol Vis Sci 1996;37:196-203.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 196-203
    • Roque, R.S.1    Imperial, C.J.2    Caldwell, R.B.3
  • 13
    • 0037375042 scopus 로고    scopus 로고
    • Activated microglia in human retinitis pigmentosa, late-onset retinal degeneration, and age-related macular degeneration
    • Gupta N, Brown KE, Milam AH: Activated microglia in human retinitis pigmentosa, late-onset retinal degeneration, and age-related macular degeneration. Exp Eye Res 2003;76:463-471.
    • (2003) Exp Eye Res , vol.76 , pp. 463-471
    • Gupta, N.1    Brown, K.E.2    Milam, A.H.3
  • 15
    • 0041837517 scopus 로고    scopus 로고
    • Characterization of activated retinal microglia following optic axotomy
    • Zhang C, Tso MO: Characterization of activated retinal microglia following optic axotomy. J Neurosci Res 2003;73:840-845.
    • (2003) J Neurosci Res , vol.73 , pp. 840-845
    • Zhang, C.1    Tso, M.O.2
  • 16
    • 0026356353 scopus 로고
    • The relationship of microglial cells to dying neurons during natural neuronal cell death and axotomy-induced degeneration of the rat retina
    • Thanos S: The relationship of microglial cells to dying neurons during natural neuronal cell death and axotomy-induced degeneration of the rat retina. Eur J Neurosci 1991;3:1189-1207.
    • (1991) Eur J Neurosci , vol.3 , pp. 1189-1207
    • Thanos, S.1
  • 17
    • 0027464886 scopus 로고
    • Treatment of the adult retina with microglia-suppressing factors retards axotomy-induced neuronal degradation and enhances axonal regeneration in vivo and in vitro
    • Thanos S, Mey J, Wild M: Treatment of the adult retina with microglia-suppressing factors retards axotomy-induced neuronal degradation and enhances axonal regeneration in vivo and in vitro. J Neurosci 1993;13:455-466.
    • (1993) J Neurosci , vol.13 , pp. 455-466
    • Thanos, S.1    Mey, J.2    Wild, M.3
  • 19
    • 0035693924 scopus 로고    scopus 로고
    • Inflammation, autotoxicity and Alzheimer disease
    • McGeer PL, McGeer EG: Inflammation, autotoxicity and Alzheimer disease. Neurobiol Aging 2001;22:799-809.
    • (2001) Neurobiol Aging , vol.22 , pp. 799-809
    • McGeer, P.L.1    McGeer, E.G.2
  • 20
    • 0029434439 scopus 로고
    • The microglial cell. A historical review
    • Barron KD: The microglial cell. A historical review. J Neurol Sci 1995;134(suppl):57-68.
    • (1995) J Neurol Sci , vol.134 , Issue.SUPPL. , pp. 57-68
    • Barron, K.D.1
  • 21
    • 0036847816 scopus 로고    scopus 로고
    • Microglia as neuroprotective, immunocompetent cells of the CNS
    • Streit WJ: Microglia as neuroprotective, immunocompetent cells of the CNS. Glia 2002;40:133-139.
    • (2002) Glia , vol.40 , pp. 133-139
    • Streit, W.J.1
  • 23
    • 0033681231 scopus 로고    scopus 로고
    • Modification of glial-neuronal cell interactions prevents photoreceptor apoptosis during light-induced retinal degeneration
    • Harada T, Harada C, Nakayama N, Okuyama S, Yoshida K, Kohsaka S, Matsuda H, Wada K: Modification of glial-neuronal cell interactions prevents photoreceptor apoptosis during light-induced retinal degeneration. Neuron 2000;26:533-541.
    • (2000) Neuron , vol.26 , pp. 533-541
    • Harada, T.1    Harada, C.2    Nakayama, N.3    Okuyama, S.4    Yoshida, K.5    Kohsaka, S.6    Matsuda, H.7    Wada, K.8
  • 24
    • 0029983724 scopus 로고    scopus 로고
    • Distinct isoforms (COX-1 and COX-2) of cyclooxygenase: Possible physiological and therapeutic implications
    • Pairet M, Engelhardt G: Distinct isoforms (COX-1 and COX-2) of cyclooxygenase: Possible physiological and therapeutic implications. Fundam Clin Pharmacol 1996;10:1-17.
    • (1996) Fundam Clin Pharmacol , vol.10 , pp. 1-17
    • Pairet, M.1    Engelhardt, G.2
  • 27
    • 0038166242 scopus 로고    scopus 로고
    • Increased activity of cyclooxygenase-2 signals early neurodegenerative events in the rat retina following transient ischemia
    • Ju WK, Kim KY, Neufeld AH: Increased activity of cyclooxygenase-2 signals early neurodegenerative events in the rat retina following transient ischemia. Exp Eye Res 2003;77:137-145.
    • (2003) Exp Eye Res , vol.77 , pp. 137-145
    • Ju, W.K.1    Kim, K.Y.2    Neufeld, A.H.3
  • 29
    • 0036790816 scopus 로고    scopus 로고
    • Decrease of proinflammatory molecules correlates with neuroprotective effect of the fluorinated salicylate triflusal after postnatal excitotoxic damage
    • Acarin L, Gonzalez B, Castellano B: Decrease of proinflammatory molecules correlates with neuroprotective effect of the fluorinated salicylate triflusal after postnatal excitotoxic damage. Stroke 2002;33:2499-2505.
    • (2002) Stroke , vol.33 , pp. 2499-2505
    • Acarin, L.1    Gonzalez, B.2    Castellano, B.3
  • 30
    • 0036753450 scopus 로고    scopus 로고
    • Cyclooxygenase and 5-lipoxygenase inhibitors protect against mononuclear phagocyte neurotoxicity
    • Klegeris A, McGeer PL: Cyclooxygenase and 5-lipoxygenase inhibitors protect against mononuclear phagocyte neurotoxicity. Neurobiol Aging 2002;23:787-794.
    • (2002) Neurobiol Aging , vol.23 , pp. 787-794
    • Klegeris, A.1    McGeer, P.L.2
  • 32
    • 1842714301 scopus 로고    scopus 로고
    • Neuroinflammation, COX-2, and ALS - A dual role?
    • Consilvio C, Vincent AM, Feldman EL: Neuroinflammation, COX-2, and ALS - A dual role? Exp Neurol 2004;187:1-10.
    • (2004) Exp Neurol , vol.187 , pp. 1-10
    • Consilvio, C.1    Vincent, A.M.2    Feldman, E.L.3
  • 33
    • 4344645719 scopus 로고    scopus 로고
    • Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease
    • Sanchez-Pernaute R, Ferree A, Cooper O, Yu M, Brownell AL, Isacson O: Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease. J Neuroinflammation 2004;1:6.
    • (2004) J Neuroinflammation , vol.1 , pp. 6
    • Sanchez-Pernaute, R.1    Ferree, A.2    Cooper, O.3    Yu, M.4    Brownell, A.L.5    Isacson, O.6
  • 34
    • 0032996598 scopus 로고    scopus 로고
    • Down-regulation of microglial cyclo-oxygenase-2 and inducible nitric oxide synthase expression by lipocortin 1
    • Minghetti L, Nicolini A, Polazzi E, Greco A, Perretti M, Parente L, Levi G: Down-regulation of microglial cyclo-oxygenase-2 and inducible nitric oxide synthase expression by lipocortin 1. Br J Pharmacol 1999;126:1307-1314.
    • (1999) Br J Pharmacol , vol.126 , pp. 1307-1314
    • Minghetti, L.1    Nicolini, A.2    Polazzi, E.3    Greco, A.4    Perretti, M.5    Parente, L.6    Levi, G.7
  • 35
    • 0033869890 scopus 로고    scopus 로고
    • Inhibition of microglial nitric oxide production by hydrocortisone and glucocorticoid precursors
    • Chang JY, Liu LZ: Inhibition of microglial nitric oxide production by hydrocortisone and glucocorticoid precursors. Neurochem Res 2000;25:903-908.
    • (2000) Neurochem Res , vol.25 , pp. 903-908
    • Chang, J.Y.1    Liu, L.Z.2
  • 36
    • 0034662247 scopus 로고    scopus 로고
    • Inhibition of microglial cell activation by cortisol
    • Drew PD, Chavis JA: Inhibition of microglial cell activation by cortisol. Brain Res Bull 2000; 52:391-396.
    • (2000) Brain Res Bull , vol.52 , pp. 391-396
    • Drew, P.D.1    Chavis, J.A.2
  • 37
    • 0030066172 scopus 로고    scopus 로고
    • Molecular cloning of F4/ 80, a murine macrophage-restricted cell surface glycoprotein with homology to the G-protein-linked transmembrane 7 hormone receptor family
    • McKnight AJ, Macfarlane AJ, Dri P, Turley L, Willis AC, Gordon S: Molecular cloning of F4/ 80, a murine macrophage-restricted cell surface glycoprotein with homology to the G-protein-linked transmembrane 7 hormone receptor family. J Biol Chem 1996;271:486-489.
    • (1996) J Biol Chem , vol.271 , pp. 486-489
    • McKnight, A.J.1    Macfarlane, A.J.2    Dri, P.3    Turley, L.4    Willis, A.C.5    Gordon, S.6
  • 38
    • 0029967194 scopus 로고    scopus 로고
    • EGF-TM7: A novel subfamily of seven-transmembrane-region leukocyte cell-surface molecules
    • McKnight AJ, Gordon S: EGF-TM7: A novel subfamily of seven-transmembrane- region leukocyte cell-surface molecules. Immunol Today 1996;17:283-287.
    • (1996) Immunol Today , vol.17 , pp. 283-287
    • McKnight, A.J.1    Gordon, S.2
  • 39
    • 0034213071 scopus 로고    scopus 로고
    • LNB-TM7, a group of seven-transmembrane proteins related to family-B G-protein-coupled receptors
    • Stacey M, Lin HH, Gordon S, McKnight AJ: LNB-TM7, a group of seven-transmembrane proteins related to family-B G-protein-coupled receptors. Trends Biochem Sci 2000;25:284-289.
    • (2000) Trends Biochem Sci , vol.25 , pp. 284-289
    • Stacey, M.1    Lin, H.H.2    Gordon, S.3    McKnight, A.J.4
  • 41
    • 0030318063 scopus 로고    scopus 로고
    • Stress, glucocorticoids, and damage to the nervous system: The current state of confusion
    • Sapolsky RM: Stress, glucocorticoids, and damage to the nervous system: The current state of confusion. Stress 1996;1:1-19.
    • (1996) Stress , vol.1 , pp. 1-19
    • Sapolsky, R.M.1
  • 42
    • 0036434191 scopus 로고    scopus 로고
    • Glucocorticoid exacerbation of gp120 neurotoxicity: Role of microglia
    • Brooke SM, Sapolsky RM. Glucocorticoid exacerbation of gp120 neurotoxicity: Role of microglia. Exp Neurol 2002;177:151-158.
    • (2002) Exp Neurol , vol.177 , pp. 151-158
    • Brooke, S.M.1    Sapolsky, R.M.2
  • 43
    • 0034820215 scopus 로고    scopus 로고
    • Action of glucocorticoids on survival of nerve cells: Promoting neurodegeneration or neuroprotection?
    • Abraham IM, Harkany T, Horvath KM, Luiten PG: Action of glucocorticoids on survival of nerve cells: Promoting neurodegeneration or neuroprotection? J Neuroendocrinol 2001;13:749-760.
    • (2001) J Neuroendocrinol , vol.13 , pp. 749-760
    • Abraham, I.M.1    Harkany, T.2    Horvath, K.M.3    Luiten, P.G.4
  • 44
    • 0028230177 scopus 로고
    • Lipocortin-1: Cellular mechanisms and clinical relevance
    • Flower RJ, Rothwell NJ: Lipocortin-1: Cellular mechanisms and clinical relevance. Trends Pharmacol Sci 1994;15:71-76.
    • (1994) Trends Pharmacol Sci , vol.15 , pp. 71-76
    • Flower, R.J.1    Rothwell, N.J.2
  • 45
    • 0029863346 scopus 로고    scopus 로고
    • Glucocorticoids differentially increase nerve growth factor and basic fibroblast growth factor expression in the rat brain
    • Mocchetti I, Spiga G, Hayes VY, Isackson PJ, Colangelo A: Glucocorticoids differentially increase nerve growth factor and basic fibroblast growth factor expression in the rat brain. J Neurosci 1996;16:2141-2148.
    • (1996) J Neurosci , vol.16 , pp. 2141-2148
    • Mocchetti, I.1    Spiga, G.2    Hayes, V.Y.3    Isackson, P.J.4    Colangelo, A.5
  • 46
    • 0038722154 scopus 로고    scopus 로고
    • Glucocorticoids play a fundamental role in protecting the brain during innate immune response
    • Nadeau S, Rivest S: Glucocorticoids play a fundamental role in protecting the brain during innate immune response. J Neurosci 2003;23:5536-5544.
    • (2003) J Neurosci , vol.23 , pp. 5536-5544
    • Nadeau, S.1    Rivest, S.2
  • 48
    • 0028231117 scopus 로고
    • Involvement of protein kinase C in the inhibition of nitric oxide production from murine microglial cells by glucocorticoid
    • Jun CD, Hoon R, Um JY, Kim TY, Kim JM, Kang SS, Kim HM, Chung HT: Involvement of protein kinase C in the inhibition of nitric oxide production from murine microglial cells by glucocorticoid. Biochem Biophys Res Commun 1994;199:633-638.
    • (1994) Biochem Biophys Res Commun , vol.199 , pp. 633-638
    • Jun, C.D.1    Hoon, R.2    Um, J.Y.3    Kim, T.Y.4    Kim, J.M.5    Kang, S.S.6    Kim, H.M.7    Chung, H.T.8
  • 50
    • 0028297676 scopus 로고
    • Involvement of the cystine transport system xc- In the macrophage-induced glutamate-dependent cytotoxicity to neurons
    • Piani D, Fontana A: Involvement of the cystine transport system xc- in the macrophage-induced glutamate-dependent cytotoxicity to neurons. J Immunol 1994;152:3578-3585.
    • (1994) J Immunol , vol.152 , pp. 3578-3585
    • Piani, D.1    Fontana, A.2
  • 51
    • 0026079784 scopus 로고
    • Effects of dexamethasone on microglial activation in vivo: Selective downregulation of major histocompatibility complex class II expression in regenerating facial nucleus
    • Kiefer R, Kreutzberg GW: Effects of dexamethasone on microglial activation in vivo: Selective downregulation of major histocompatibility complex class II expression in regenerating facial nucleus. J Neuroimmunol 1991;34:99-108.
    • (1991) J Neuroimmunol , vol.34 , pp. 99-108
    • Kiefer, R.1    Kreutzberg, G.W.2
  • 53
    • 0037986693 scopus 로고    scopus 로고
    • Salicylate enhances necrosis and apoptosis mediated by the mitochondrial permeability transition
    • Oh KW, Qian T, Brenner DA, Lemasters JJ: Salicylate enhances necrosis and apoptosis mediated by the mitochondrial permeability transition. Toxicol Sci 2003;73:44-52.
    • (2003) Toxicol Sci , vol.73 , pp. 44-52
    • Oh, K.W.1    Qian, T.2    Brenner, D.A.3    Lemasters, J.J.4
  • 54
    • 0036912306 scopus 로고    scopus 로고
    • Aspirin and sodium salicylate inhibit proliferation and induce apoptosis in rheumatoid synovial cells
    • Yamazaki R, Kusunoki N, Matsuzaki T, Hashimoto S, Kawai S: Aspirin and sodium salicylate inhibit proliferation and induce apoptosis in rheumatoid synovial cells. J Pharm Pharmacol 2002;54:1675-1679.
    • (2002) J Pharm Pharmacol , vol.54 , pp. 1675-1679
    • Yamazaki, R.1    Kusunoki, N.2    Matsuzaki, T.3    Hashimoto, S.4    Kawai, S.5
  • 55
    • 0034806996 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs induce apoptosis in gastric cancer cells through up-regulation of bax and bak
    • Zhou XM, Wong BC, Fan XM, Zhang HB, Lin MC, Kung HF, Fan DM, Lam SK: Non-steroidal anti-inflammatory drugs induce apoptosis in gastric cancer cells through up-regulation of bax and bak. Carcinogenesis 2001;22:1393-1397.
    • (2001) Carcinogenesis , vol.22 , pp. 1393-1397
    • Zhou, X.M.1    Wong, B.C.2    Fan, X.M.3    Zhang, H.B.4    Lin, M.C.5    Kung, H.F.6    Fan, D.M.7    Lam, S.K.8
  • 59
    • 0041876229 scopus 로고    scopus 로고
    • Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid β42 production by direct modulation of γ-secretase activity
    • Weggen S, Eriksen JL, Sagi S A, Pietrzik CU, Ozols V, Fauq A, Golde TE, Koo EH: Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid β42 production by direct modulation of γ-secretase activity. J Biol Chem 2003; 278:31831-31837.
    • (2003) J Biol Chem , vol.278 , pp. 31831-31837
    • Weggen, S.1    Eriksen, J.L.2    Sagi, S.A.3    Pietrzik, C.U.4    Ozols, V.5    Fauq, A.6    Golde, T.E.7    Koo, E.H.8


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