-
1
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon DJ, Godolphin W, Jones LA, et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science, 1989;244:707-712.
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
-
2
-
-
0024259860
-
Overexpression of either c-myc or c-erbB-2/neu proto-oncogenes in human breast carcinomas: Correlation with poor prognosis
-
Guerin M, Barrois M, Terrier MJ, et al. Overexpression of either c-myc or c-erbB-2/neu proto-oncogenes in human breast carcinomas: correlation with poor prognosis. Oncogens Res. 1988;3:21-31.
-
(1988)
Oncogens Res
, vol.3
, pp. 21-31
-
-
Guerin, M.1
Barrois, M.2
Terrier, M.J.3
-
3
-
-
0025360473
-
HER-2/neu amplification predicts poor survival in node-positive breast cancer
-
Borg A, Tandon AK, Sigurdsson H, et al. HER-2/neu amplification predicts poor survival in node-positive breast cancer. Cancer Res. 1990;50:4332-4337.
-
(1990)
Cancer Res
, vol.50
, pp. 4332-4337
-
-
Borg, A.1
Tandon, A.K.2
Sigurdsson, H.3
-
4
-
-
0026582760
-
HER-2/neu amplification and Overexpression in primary human breast cancer is associated with early metastasis
-
Tiwari RK, Borgen PI, Wong GY, et al. HER-2/neu amplification and Overexpression in primary human breast cancer is associated with early metastasis. Anricancer Res. 1992;12:419-425.
-
(1992)
Anricancer Res
, vol.12
, pp. 419-425
-
-
Tiwari, R.K.1
Borgen, P.I.2
Wong, G.Y.3
-
5
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
Vogel CL, Cobleigh MA, Tripathy D, et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol. 2002;20:719-726.
-
(2002)
J Clin Oncol
, vol.20
, pp. 719-726
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
-
6
-
-
0035873815
-
Weekly trastuzumab and paclitaxel therapy for metastatic breast cancer with analysis of efficacy by HER2 immunophenotype and gene amplification
-
Seidman AD, Fornier MN, Esteva FJ, et al. Weekly trastuzumab and paclitaxel therapy for metastatic breast cancer with analysis of efficacy by HER2 immunophenotype and gene amplification. J Clin Oncol. 2001;19:2587-2595.
-
(2001)
J Clin Oncol
, vol.19
, pp. 2587-2595
-
-
Seidman, A.D.1
Fornier, M.N.2
Esteva, F.J.3
-
7
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2, N Engl J Med. 2001;344:783-792.
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
8
-
-
0034473393
-
Trastuzumab and chemotherapeutics: Drug interactions and synergies
-
Pegram MD, Lopez A, Konecny G, et al. Trastuzumab and chemotherapeutics: drug interactions and synergies. Semin Oncol. 2000;27:21-25.
-
(2000)
Semin Oncol
, vol.27
, pp. 21-25
-
-
Pegram, M.D.1
Lopez, A.2
Konecny, G.3
-
9
-
-
0000676798
-
Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22
-
Tsai-Pflugfelder M, Liu LF, Liu AA, et al. Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22. Proc Natl Acad Sci U S A. 1988;85:7177-7181.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 7177-7181
-
-
Tsai-Pflugfelder, M.1
Liu, L.F.2
Liu, A.A.3
-
10
-
-
0024453524
-
In vivo phosphorylation of the 170-kDa form of eukaryotic DNA topoisomerase II: Cell cycle analysis
-
Heck MM, Hittelman WN, Earnshaw WC. In vivo phosphorylation of the 170-kDa form of eukaryotic DNA topoisomerase II: cell cycle analysis. J Biol Chem. 1989;264:15161-15164.
-
(1989)
J Biol Chem
, vol.264
, pp. 15161-15164
-
-
Heck, M.M.1
Hittelman, W.N.2
Earnshaw, W.C.3
-
11
-
-
0030758268
-
Simplification of DNA topology below equilibrium values by type II topoisomerases
-
Rybenkov VV, Ullsperger C, Vologodskii AV, et al. Simplification of DNA topology below equilibrium values by type II topoisomerases. Science. 1997;277:690-693.
-
(1997)
Science
, vol.277
, pp. 690-693
-
-
Rybenkov, V.V.1
Ullsperger, C.2
Vologodskii, A.V.3
-
12
-
-
0033870292
-
Amplification and deletion of topoisomerase IIalpha associate with erbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer
-
Jarvinen TA, Tanner M, Rantanen V, et al. Amplification and deletion of topoisomerase IIalpha associate with erbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer. Am J Pathol. 2000;156:839-847.
-
(2000)
Am J Pathol
, vol.156
, pp. 839-847
-
-
Jarvinen, T.A.1
Tanner, M.2
Rantanen, V.3
-
13
-
-
0043129024
-
Induction chemotherapy for breast carcinoma: Predictive markers and relation with outcome
-
Penault-Llorca F, Cayre A, Bouchet MF, et al. Induction chemotherapy for breast carcinoma: predictive markers and relation with outcome. Int J Oncol. 2003;22:1319-1325.
-
(2003)
Int J Oncol
, vol.22
, pp. 1319-1325
-
-
Penault-Llorca, F.1
Cayre, A.2
Bouchet, M.F.3
-
14
-
-
0038612855
-
Role of proliferation in HER2 status predicted response to doxorubicin
-
Campiglio M, Somenzi G, Olgiati C, et al. Role of proliferation in HER2 status predicted response to doxorubicin. Int J Cancer. 2003;105:568-573.
-
(2003)
Int J Cancer
, vol.105
, pp. 568-573
-
-
Campiglio, M.1
Somenzi, G.2
Olgiati, C.3
-
15
-
-
0037738887
-
HER-2/neu and topoisomerase Ilalpha in breast cancer
-
Jarvinen TA, Liu ET. HER-2/neu and topoisomerase Ilalpha in breast cancer. Breast Cancer Res Treat. 2003;78:299-311.
-
(2003)
Breast Cancer Res Treat
, vol.78
, pp. 299-311
-
-
Jarvinen, T.A.1
Liu, E.T.2
-
16
-
-
0043145754
-
Characterization of topoisomerase II alpha gene amplification and deletion in breast cancer
-
Jarvinen TA, Tanner M, Barlund M, et al. Characterization of topoisomerase II alpha gene amplification and deletion in breast cancer. Genes Chromosomes Cancer. 1999;26:142-150.
-
(1999)
Genes Chromosomes Cancer
, vol.26
, pp. 142-150
-
-
Jarvinen, T.A.1
Tanner, M.2
Barlund, M.3
-
17
-
-
0141614011
-
Topoisomerase II alpha as a marker predicting the efficacy of anthracyclines in breast cancer: Are we at the end of the beginning?
-
Di Leo A, Isola J. Topoisomerase II alpha as a marker predicting the efficacy of anthracyclines in breast cancer: are we at the end of the beginning? Clin Breast Cancer. 2003;4:179-186.
-
(2003)
Clin Breast Cancer
, vol.4
, pp. 179-186
-
-
Di Leo, A.1
Isola, J.2
-
18
-
-
0035061867
-
Tissue microarray technology for high-throughput molecular profiling of cancer
-
Kallioniemi OP, Wagner U, Kononen J, et al. Tissue microarray technology for high-throughput molecular profiling of cancer. Hum Mol Genet, 2001;10:657-662.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 657-662
-
-
Kallioniemi, O.P.1
Wagner, U.2
Kononen, J.3
-
19
-
-
0031822837
-
Tissue microarrays for high-throughput molecular profiling of tumor specimens
-
Kononen J, Bubendorf L, Kallioniemi A, et al. Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med. 1998;4:844-847.
-
(1998)
Nat Med
, vol.4
, pp. 844-847
-
-
Kononen, J.1
Bubendorf, L.2
Kallioniemi, A.3
-
20
-
-
0036178508
-
Tissue microarrays: A powerful tool for high-throughput analysis of clinical specimens: a review of the method with validation data
-
Skacel M, Skilton B, Pettay JD, et al. Tissue microarrays: a powerful tool for high-throughput analysis of clinical specimens: a review of the method with validation data. Appl Immunohistochem Mol Morphol. 2002;10:-1-6.
-
(2002)
Appl Immunohistochem Mol Morphol
, vol.10
, pp. 1-6
-
-
Skacel, M.1
Skilton, B.2
Pettay, J.D.3
-
21
-
-
0035878845
-
Amplification of HER-2/neu and topoisomerase IIalpha in primary and metastatic breast cancer
-
Tanner M, Jarvinen P, Isola J. Amplification of HER-2/neu and topoisomerase IIalpha in primary and metastatic breast cancer. Cancer Res. 2001;61:5345-5348.
-
(2001)
Cancer Res
, vol.61
, pp. 5345-5348
-
-
Tanner, M.1
Jarvinen, P.2
Isola, J.3
-
22
-
-
0036554731
-
Amplification and overexpression of topoisomerase Ilalpha predict response to anthracycline-based therapy in locally advanced breast cancer
-
Coon JS, Marcus E, Gupta-Burt S, et al. Amplification and overexpression of topoisomerase Ilalpha predict response to anthracycline-based therapy in locally advanced breast cancer. Clin Cancer Res. 2002;8:1061-1067.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1061-1067
-
-
Coon, J.S.1
Marcus, E.2
Gupta-Burt, S.3
-
23
-
-
0030904279
-
Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons
-
Coquelle A, Pipiras E, Toledo F, et al. Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons. Cell. 1997;89:215-225.
-
(1997)
Cell
, vol.89
, pp. 215-225
-
-
Coquelle, A.1
Pipiras, E.2
Toledo, F.3
-
24
-
-
0032472367
-
Interstitial deletions and intrachromosomal amplification initiated from a double-strand break targeted to a mammalian chromosome
-
Pipiras E, Coquelle A, Bieth A, et al. Interstitial deletions and intrachromosomal amplification initiated from a double-strand break targeted to a mammalian chromosome. EMBO J. 1998;17:325-333.
-
(1998)
EMBO J
, vol.17
, pp. 325-333
-
-
Pipiras, E.1
Coquelle, A.2
Bieth, A.3
-
25
-
-
1542343905
-
Amplification of the TOP2A gene does not predict high levels of topoisomerase II alpha protein in human breast tumor samples
-
Mueller RE, Parkes RK, Andrulis I, et al. Amplification of the TOP2A gene does not predict high levels of topoisomerase II alpha protein in human breast tumor samples. Genes Chromosomes Cancer, 2004;39:288-297.
-
(2004)
Genes Chromosomes Cancer
, vol.39
, pp. 288-297
-
-
Mueller, R.E.1
Parkes, R.K.2
Andrulis, I.3
-
26
-
-
0031450928
-
Human deoxyribonucleic acid topoisomerases: Molecular targets of anticancer drugs
-
Holden JA. Human deoxyribonucleic acid topoisomerases: molecular targets of anticancer drugs. Ann Clin Lab Sci. 1997;27:402-412.
-
(1997)
Ann Clin Lab Sci
, vol.27
, pp. 402-412
-
-
Holden, J.A.1
|