-
1
-
-
0022647432
-
The product of the human c-erbB-2 gene: A 185-kilodalton glycoprotein with tyrosine kinase activity
-
Akiyama T, Sudo C, Ogawara H, et al: The product of the human c-erbB-2 gene: A 185-kilodalton glycoprotein with tyrosine kinase activity. Science 232:1644-1646, 1986
-
(1986)
Science
, vol.232
, pp. 1644-1646
-
-
Akiyama, T.1
Sudo, C.2
Ogawara, H.3
-
2
-
-
0022399581
-
Tyrosine kinase receptor with extensive homology to EGC receptor shares chromosomal location with neu oncogene
-
Coussens L, Yang-Feng TL, Liao YC, et al: Tyrosine kinase receptor with extensive homology to EGC receptor shares chromosomal location with neu oncogene. Science 230:1132-1139, 1985
-
(1985)
Science
, vol.230
, pp. 1132-1139
-
-
Coussens, L.1
Yang-Feng, T.L.2
Liao, Y.C.3
-
3
-
-
0026739541
-
Transformation mediated by the human HER-2 gene independent of epidermal growth factor receptor
-
Chazin VR, Kaleko M, Miller AD, et al: Transformation mediated by the human HER-2 gene independent of epidermal growth factor receptor. Oncogene 7:1859-1866, 1992
-
(1992)
Oncogene
, vol.7
, pp. 1859-1866
-
-
Chazin, V.R.1
Kaleko, M.2
Miller, A.D.3
-
4
-
-
0023196582
-
ErbB2 is a potent oncogene when overexpressed in NIH/3T3 cells
-
Di Fiore PP, Pierce JH, Kraus MH, et al: ErbB2 is a potent oncogene when overexpressed in NIH/3T3 cells. Science 237:178-182, 1987
-
(1987)
Science
, vol.237
, pp. 178-182
-
-
Di Fiore, P.P.1
Pierce, J.H.2
Kraus, M.H.3
-
5
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/ neu oncogene
-
Slamon DJ, Clark GM, Wong SG, et al: Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/ neu oncogene. Science 235:177-235, 1987
-
(1987)
Science
, vol.235
, pp. 177-235
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
-
6
-
-
0026625217
-
Prognostic importance of c-erbB-2 expression in breast cancer
-
Gusterson BA, Gelber RD, Goldhirsch A, et al: Prognostic importance of c-erbB-2 expression in breast cancer. J Clin Oncol 7:1049-1056, 1992
-
(1992)
J Clin Oncol
, vol.7
, pp. 1049-1056
-
-
Gusterson, B.A.1
Gelber, R.D.2
Goldhirsch, A.3
-
7
-
-
0031954313
-
neu/erbB-2 amplification identifies a poor-prognosis group ot women with node-negative breast cancer
-
Andrulis IL, Bull SB, Blackstein ME, et al: neu/erbB-2 amplification identifies a poor-prognosis group ot women with node-negative breast cancer. J Clin Oncol 16:1340-1349, 1998
-
(1998)
J Clin Oncol
, vol.16
, pp. 1340-1349
-
-
Andrulis, I.L.1
Bull, S.B.2
Blackstein, M.E.3
-
8
-
-
0029039990
-
The c-erbB-2 proto-oncogene as a prognostic and predictive marker in breast cancer: A paradigm for the development of other macromolecular markers - A review
-
Ravdin PM, Chamness GC: The c-erbB-2 proto-oncogene as a prognostic and predictive marker in breast cancer: A paradigm for the development of other macromolecular markers - A review. Gene 159:19-27, 1995
-
(1995)
Gene
, vol.159
, pp. 19-27
-
-
Ravdin, P.M.1
Chamness, G.C.2
-
9
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon DJ, Godolphin W, Jones LA, et al: Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244:707-712, 1989
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
-
10
-
-
0023857935
-
Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading
-
Berger MS, Locher GW, Saurer S, et al: Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading. Cancer Res 48:1238-1243, 1998
-
(1998)
Cancer Res
, vol.48
, pp. 1238-1243
-
-
Berger, M.S.1
Locher, G.W.2
Saurer, S.3
-
11
-
-
0033965962
-
Assessment of HER2 status in breast cancer: Why, when, and how?
-
Dowsett M, Cooke T, Ellis I, et al: Assessment of HER2 status in breast cancer: Why, when, and how? Eur J Cancer 36:170-176, 2000
-
(2000)
Eur J Cancer
, vol.36
, pp. 170-176
-
-
Dowsett, M.1
Cooke, T.2
Ellis, I.3
-
12
-
-
0033055699
-
Comparison of fluorescence in situ hybridization and immunohistochemistry for the evaluation of HER-2/neu in breast cancer
-
Jacobs TW, Gown AM, Yaziji H, et al: Comparison of fluorescence in situ hybridization and immunohistochemistry for the evaluation of HER-2/neu in breast cancer. J Clin Oncol 17:1974-1982, 1999
-
(1999)
J Clin Oncol
, vol.17
, pp. 1974-1982
-
-
Jacobs, T.W.1
Gown, A.M.2
Yaziji, H.3
-
13
-
-
0033048939
-
Specificity of HercepT-est in determining HER-2/neu status of breast cancers using the United States Food and Drug Administration-approved scoring system
-
Jacobs TW, Gown AM, Yaziji H, et al: Specificity of HercepT-est in determining HER-2/neu status of breast cancers using the United States Food and Drug Administration-approved scoring system. J Clin Oncol 17:1983-1987, 1999
-
(1999)
J Clin Oncol
, vol.17
, pp. 1983-1987
-
-
Jacobs, T.W.1
Gown, A.M.2
Yaziji, H.3
-
14
-
-
0032921406
-
Increased HER2 with U.S. Food and Drug Administration-approved antibody
-
letter
-
Roche PC, Ingle JN: Increased HER2 with U.S. Food and Drug Administration-approved antibody. J Clin Oncol 17:434, 1999 (letter)
-
(1999)
J Clin Oncol
, vol.17
, pp. 434
-
-
Roche, P.C.1
Ingle, J.N.2
-
15
-
-
0032922148
-
Immunohistochemical assays for HER2 overexpression
-
letter
-
Maia DM: Immunohistochemical assays for HER2 overexpression. J Clin Oncol 17:1650, 1999 (letter)
-
(1999)
J Clin Oncol
, vol.17
, pp. 1650
-
-
Maia, D.M.1
-
16
-
-
0030763180
-
Quantitation of HER-2/neu and c-myc gene amplification in breast carcinoma using fluorescence in situ hybridization
-
Persons DL, Borelli KA, Hsu PH: Quantitation of HER-2/neu and c-myc gene amplification in breast carcinoma using fluorescence in situ hybridization. Mod Pathol 10:720-727, 1997
-
(1997)
Mod Pathol
, vol.10
, pp. 720-727
-
-
Persons, D.L.1
Borelli, K.A.2
Hsu, P.H.3
-
17
-
-
0033625553
-
HER overexpression in human breast cancer using molecular and immunohistochemical methods
-
HER overexpression in human breast cancer using molecular and immunohistochemical methods. Cancer Invest 18:336-342, 2000
-
(2000)
Cancer Invest
, vol.18
, pp. 336-342
-
-
Johnson, R.C.1
Ricci, A.2
Cartun, R.W.3
-
18
-
-
0033973884
-
Determination of HER-2/neu status in breast carcinoma: Comparative analysis of immunohistochemistry and fluorescent in situ hybridization
-
Jimenez RE, Wallis T, Tabasczka P, et al: Determination of HER-2/neu status in breast carcinoma: Comparative analysis of immunohistochemistry and fluorescent in situ hybridization. Mod Pathol 13:37-45, 2000
-
(2000)
Mod Pathol
, vol.13
, pp. 37-45
-
-
Jimenez, R.E.1
Wallis, T.2
Tabasczka, P.3
-
19
-
-
0029884715
-
Detection and quantitation of HER-2/neu gene amplification in human breast cancer archival material using fluorescent in situ hybridization
-
Pauletti G, Godolphin W, Press MF, et al: Detection and quantitation of HER-2/neu gene amplification in human breast cancer archival material using fluorescent in situ hybridization. Oncogene 13:63-72, 1996
-
(1996)
Oncogene
, vol.13
, pp. 63-72
-
-
Pauletti, G.1
Godolphin, W.2
Press, M.F.3
-
20
-
-
0024516756
-
Overexpression of the c-erbB-2 protein in human breast tumor cell lines
-
Hynes NE, Gerber HA, Saurer S, et al: Overexpression of the c-erbB-2 protein in human breast tumor cell lines. J Cell Biochem 39:167-173, 1989
-
(1989)
J Cell Biochem
, vol.39
, pp. 167-173
-
-
Hynes, N.E.1
Gerber, H.A.2
Saurer, S.3
-
21
-
-
0028848397
-
HER-2 overexpression, and intratumor heterogeneity in human breast cancer
-
HER-2 overexpression, and intratumor heterogeneity in human breast cancer. Cancer Res 55:5400-5407, 1995
-
(1995)
Cancer Res
, vol.55
, pp. 5400-5407
-
-
Szöllösi, J.1
Balázs, M.2
Feuerstein, B.G.3
-
22
-
-
0027443765
-
Monoclonal antibodies directed to the erbB-2 receptor inhibit in vivo tumor cell growth
-
Harwerth IM, Wels W, Schlegel J, et al: Monoclonal antibodies directed to the erbB-2 receptor inhibit in vivo tumor cell growth. Br J Cancer 68:1140-1145, 1993
-
(1993)
Br J Cancer
, vol.68
, pp. 1140-1145
-
-
Harwerth, I.M.1
Wels, W.2
Schlegel, J.3
-
23
-
-
0032850677
-
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2 overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
-
Cobleigh MA, Vogel CL, Tripathy D, et al: Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2 overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 17:2639-2648, 1999
-
(1999)
J Clin Oncol
, vol.17
, pp. 2639-2648
-
-
Cobleigh, M.A.1
Vogel, C.L.2
Tripathy, D.3
-
24
-
-
0029991439
-
HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer
-
HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer. J Clin Oncol 14:737-744, 1996
-
(1996)
J Clin Oncol
, vol.14
, pp. 737-744
-
-
Baselga, J.1
Tripathy, D.2
Mendelsohn, J.3
-
25
-
-
0001793693
-
First-line, nonhormonal treatment of women with HER2 overexpressing metastatic breast cancer with herceptin (trastuzumab, humanized anti-HER2 antibody)
-
abstr 275
-
Vogel C, Cobleigh M, Tripathy D, et al: First-line, nonhormonal treatment of women with HER2 overexpressing metastatic breast cancer with Herceptin (trastuzumab, humanized anti-HER2 antibody). Proc Am Soc Clin Oncol 19:71a, 2000 (abstr 275)
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
-
-
Vogel, C.1
Cobleigh, M.2
Tripathy, D.3
-
26
-
-
0032127350
-
Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts
-
Baselga J, Norton L, Albanell J, et al: Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts. Cancer Res 58:2825-2831, 1998
-
(1998)
Cancer Res
, vol.58
, pp. 2825-2831
-
-
Baselga, J.1
Norton, L.2
Albanell, J.3
-
27
-
-
0032578797
-
Remission of human breast cancer xenografts on therapy with humanized monoclonal antibody to HER-2 receptor and DNA-reactive drugs
-
Pietras RJ, Pegram MD, Finn RS, et al: Remission of human breast cancer xenografts on therapy with humanized monoclonal antibody to HER-2 receptor and DNA-reactive drugs. Oncogene 17:2235-2249, 1998
-
(1998)
Oncogene
, vol.17
, pp. 2235-2249
-
-
Pietras, R.J.1
Pegram, M.D.2
Finn, R.S.3
-
28
-
-
0033118889
-
Inhibitory effects of combination of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers
-
Pegram M, Hsu S, Lewis G, et al: Inhibitory effects of combination of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers. Oncogene 18:2241-2251, 1999
-
(1999)
Oncogene
, vol.18
, pp. 2241-2251
-
-
Pegram, M.1
Hsu, S.2
Lewis, G.3
-
29
-
-
0031903646
-
HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment
-
HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment. J Clin Oncol 16:2659-2671, 1998
-
(1998)
J Clin Oncol
, vol.16
, pp. 2659-2671
-
-
Pegram, M.D.1
Lipton, A.2
Hayes, D.F.3
-
30
-
-
0000405942
-
Addition of Herceptin (humanized anti-HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer (HER2+/MBC) markedly increases anticancer activity: A randomized multinational controlled phase III trial
-
abstr 377
-
Slamon D, Leyland-Jones B, Shak S, et al: Addition of Herceptin (humanized anti-HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer (HER2+/MBC) markedly increases anticancer activity: A randomized multinational controlled phase III trial. Proc Am Soc Clin Oncol 17:98a, 1998 (abstr 377)
-
(1998)
Proc Am Soc Clin Oncol
, vol.17
-
-
Slamon, D.1
Leyland-Jones, B.2
Shak, S.3
-
31
-
-
0000212829
-
Overall survival (OS) advantage to simultaneous chemotherapy (CRx) plus the humanized anti-HER2 monoclonal antibody Herceptin (H) in HER2-overexpressing (HER2+) metastatic breast cancer
-
abstr 483
-
Norton L, Slamon D, Leyland-Jones B, et al: Overall survival (OS) advantage to simultaneous chemotherapy (CRx) plus the humanized anti-HER2 monoclonal antibody Herceptin (H) in HER2-overexpressing (HER2+) metastatic breast cancer. Proc Am Soc Clin Oncol 18:127a, 1999 (abstr 483)
-
(1999)
Proc Am Soc Clin Oncol
, vol.18
-
-
Norton, L.1
Slamon, D.2
Leyland-Jones, B.3
-
32
-
-
0003304702
-
Characterization of cardiac dysfunction observed in the Herceptin (trastuzumab) clinical trials
-
abstr
-
Hudis C, Seidman A, Paton V, et al: Characterization of cardiac dysfunction observed in the Herceptin (trastuzumab) clinical trials. Breast Cancer Res Treat 50:232, 1998 (abstr)
-
(1998)
Breast Cancer Res Treat
, vol.50
, pp. 232
-
-
Hudis, C.1
Seidman, A.2
Paton, V.3
-
33
-
-
0031757277
-
Dose-dense therapy with weekly 1-hour paclitaxel infusions in the treatment of metastatic breast cancer
-
Seidman AD, Hudis CA, Albanel J, et al: Dose-dense therapy with weekly 1-hour paclitaxel infusions in the treatment of metastatic breast cancer. J Clin Oncol 16:3353-3361, 1998
-
(1998)
J Clin Oncol
, vol.16
, pp. 3353-3361
-
-
Seidman, A.D.1
Hudis, C.A.2
Albanel, J.3
-
34
-
-
0003198490
-
A large phase II trial of paclitaxel administered as a weekly one hour infusion in patients with metastatic breast cancer
-
abstr 480
-
Perez EA, Irwin DH, Patel R, et al: A large phase II trial of paclitaxel administered as a weekly one hour infusion in patients with metastatic breast cancer. Proc Am Soc Clin Oncol 18:126a, 1999 (abstr 480)
-
(1999)
Proc Am Soc Clin Oncol
, vol.18
-
-
Perez, E.A.1
Irwin, D.H.2
Patel, R.3
-
35
-
-
0000731068
-
Phase II study to evaluate the efficacy of weekly paclitaxel (WP) in patients with metastatic breast cancer (MBC) who have failed prior anthracycline (A) +/-taxane (T) therapy
-
abstr 470
-
Waintraub SE, Cantwell S, DeVries J: Phase II study to evaluate the efficacy of weekly paclitaxel (WP) in patients with metastatic breast cancer (MBC) who have failed prior anthracycline (A) +/-taxane (T) therapy. Proc Am Soc Clin Oncol 19:121a, 2000 (abstr 470)
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
-
-
Waintraub, S.E.1
Cantwell, S.2
DeVries, J.3
-
36
-
-
0000901072
-
Phase II study of weekly paclitaxel (P) treatment in recurrent breast cancer after high-dose chemotherapy (HDC)
-
abstr 245
-
Sola C, Lluch A, Garcia-Conde J, et al: Phase II study of weekly paclitaxel (P) treatment in recurrent breast cancer after high-dose chemotherapy (HDC). Proc Am Soc Clin Oncol 18:65a, 1999 (abstr 245)
-
(1999)
Proc Am Soc Clin Oncol
, vol.18
-
-
Sola, C.1
Lluch, A.2
Garcia-Conde, J.3
-
37
-
-
0003302513
-
A promising second line treatment with weekly Taxol (T) in anthracycline recurrent, advanced breast cancer (ABC) patients (PTS)
-
abstr 515
-
Mickiewicz E, Alvarez AM, Brosio C, et al: A promising second line treatment with weekly Taxol (T) in anthracycline recurrent, advanced breast cancer (ABC) patients (PTS). Proc Am Soc Clin Oncol 18:135a, 1999 (abstr 515)
-
(1999)
Proc Am Soc Clin Oncol
, vol.18
-
-
Mickiewicz, E.1
Alvarez, A.M.2
Brosio, C.3
-
38
-
-
0000693262
-
Reinduction of response with weekly Taxol (T) in advanced breast cancer (ABC)
-
abstr 636
-
Alvarez AM, Mickiewicz E, Brosio C, et al: Reinduction of response with weekly Taxol (T) in advanced breast cancer (ABC). Proc Am Soc Clin Oncol 18:165a, 1999 (abstr 636)
-
(1999)
Proc Am Soc Clin Oncol
, vol.18
-
-
Alvarez, A.M.1
Mickiewicz, E.2
Brosio, C.3
-
39
-
-
0003331643
-
Long-term weekly paclitaxel (P) in metastatic breast cancer (MBC): A phase II trial in pretreated patients (pts)
-
abstr
-
Breier S, Lebedinsky C, Ayiviri A, et al: Long-term weekly paclitaxel (P) in metastatic breast cancer (MBC): A phase II trial in pretreated patients (pts). Proc Am Soc Clin Oncol 17:192a, 1998 (abstr)
-
(1998)
Proc Am Soc Clin Oncol
, vol.17
-
-
Breier, S.1
Lebedinsky, C.2
Ayiviri, A.3
-
41
-
-
0029045110
-
Central nervous system progression of metastatic breast cancer in patients treated with paclitaxel
-
Freilich RJ, Seidman AD, DeAngelis LM: Central nervous system progression of metastatic breast cancer in patients treated with paclitaxel. Cancer 76:232-236, 1995
-
(1995)
Cancer
, vol.76
, pp. 232-236
-
-
Freilich, R.J.1
Seidman, A.D.2
DeAngelis, L.M.3
-
42
-
-
0000153682
-
The concordance between the clinical trials assay (CTA) and fluorescence in situ hybridization (FISH) in the herceptin pivotal trials
-
abstr 291
-
Mass RD, Sanders C, Charlene K, et al: The concordance between the clinical trials assay (CTA) and fluorescence in situ hybridization (FISH) in the Herceptin pivotal trials. Proc Am Soc Clin Oncol 19:75a, 2000 (abstr 291)
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
-
-
Mass, R.D.1
Sanders, C.2
Charlene, K.3
|