-
1
-
-
0010142265
-
Tryptophan synthase: A multienzyme complex with an intramolecular tunnel
-
Miles, E. W. (2001) Tryptophan synthase: A multienzyme complex with an intramolecular tunnel, Chem. Rec. 1, 140-151.
-
(2001)
Chem. Rec.
, vol.1
, pp. 140-151
-
-
Miles, E.W.1
-
3
-
-
0004488109
-
The exclusion of free indole as an intermediate in the biosynthesis of tryptophan in Neurospora crassa
-
Yanofsky, C., and Rachmeler, M. (1958) The exclusion of free indole as an intermediate in the biosynthesis of tryptophan in Neurospora crassa, Biochim. Biophys. Acta. 28, 640-641.
-
(1958)
Biochim. Biophys. Acta.
, vol.28
, pp. 640-641
-
-
Yanofsky, C.1
Rachmeler, M.2
-
4
-
-
0025916089
-
Serine modulates substrate channeling in tryptophan synthase: A novel intersubunit triggering mechanism
-
Anderson, K., Miles, E. W., and Johnson, K. A. (1991) Serine modulates substrate channeling in tryptophan synthase: A novel intersubunit triggering mechanism, J. Biol. Chem. 266, 8020-8033.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 8020-8033
-
-
Anderson, K.1
Miles, E.W.2
Johnson, K.A.3
-
5
-
-
0025006579
-
The tryptophan synthase bienzyme complex transfers indole between the α- And β-sites via a 25-30 Å long tunnel
-
Dunn, M. F., Aguilar, V., Brzovic, P., Drewe, W. F., Jr., Houben, K. F., Leja, C. A., and Roy, M. (1990) The tryptophan synthase bienzyme complex transfers indole between the α- and β-sites via a 25-30 Å long tunnel, Biochemistry 29, 8598-8607.
-
(1990)
Biochemistry
, vol.29
, pp. 8598-8607
-
-
Dunn, M.F.1
Aguilar, V.2
Brzovic, P.3
Drewe Jr., W.F.4
Houben, K.F.5
Leja, C.A.6
Roy, M.7
-
6
-
-
0025980188
-
Reciprocal communication between the lyase and synthase active sites of the tryptophan synthase bienzyme complex
-
Kirschner, K., Lane, A. N., and Strasser, A. W. M. (1991) Reciprocal communication between the lyase and synthase active sites of the tryptophan synthase bienzyme complex, Biochemistry 30, 472-478.
-
(1991)
Biochemistry
, vol.30
, pp. 472-478
-
-
Kirschner, K.1
Lane, A.N.2
Strasser, A.W.M.3
-
7
-
-
0034712647
-
Regulation of tryptophan synthase by temperature, monovalent cations, and an allosteric ligand: Evidence from Arrhenius plots, absorption spectra, and primary kinetic isotope effects
-
Fan, Y.-X., McPhie, P., and Miles, E. W. (2000) Regulation of tryptophan synthase by temperature, monovalent cations, and an allosteric ligand: Evidence from Arrhenius plots, absorption spectra, and primary kinetic isotope effects, Biochemistry 39, 4692-4703.
-
(2000)
Biochemistry
, vol.39
, pp. 4692-4703
-
-
Fan, Y.-X.1
McPhie, P.2
Miles, E.W.3
-
9
-
-
0035957229
-
Investigation of allosteric linkages in the regulation of tryptophan synthase: The roles of salt bridges and monovalent cations probed by site-directed mutation, optical spectroscopy, and kinetics
-
Weber-Ban, E., Hur, O., Bagwell, C., Banik. U., Yang, L.-H., Miles, E. W., and Dunn, M. F. (2001) Investigation of allosteric linkages in the regulation of tryptophan synthase: The roles of salt bridges and monovalent cations probed by site-directed mutation, optical spectroscopy, and kinetics, Biochemistry 40, 3497-3511.
-
(2001)
Biochemistry
, vol.40
, pp. 3497-3511
-
-
Weber-Ban, E.1
Hur, O.2
Bagwell, C.3
Banik, U.4
Yang, L.-H.5
Miles, E.W.6
Dunn, M.F.7
-
11
-
-
0029117821
-
Monovalent metal ions play an essential role in catalysis and intersubunit communication in the tryptophan synthase bienzyme complex
-
Woehl, E., and Dunn, M. F. (1995) Monovalent metal ions play an essential role in catalysis and intersubunit communication in the tryptophan synthase bienzyme complex, Biochemistry 34, 9466-9476.
-
(1995)
Biochemistry
, vol.34
, pp. 9466-9476
-
-
Woehl, E.1
Dunn, M.F.2
-
12
-
-
0033152545
-
Mechanisms of monovalent cation action in enzyme catalysis: The tryptophan synthase α-, β-, and αβ-reactions
-
Woehl, E., and Dunn, M. F. (1999) Mechanisms of monovalent cation action in enzyme catalysis: The tryptophan synthase α-, β-, and αβ-reactions, Biochemistry 38, 7131-7141.
-
(1999)
Biochemistry
, vol.38
, pp. 7131-7141
-
-
Woehl, E.1
Dunn, M.F.2
-
13
-
-
0028286273
-
2 complex from Salmonella typhimurium
-
2 complex from Salmonella typhimurium, J. Biol. Chem. 269, 16486-16492.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 16486-16492
-
-
Ahmed, S.A.1
Miles, E.W.2
-
14
-
-
0029825794
-
2 complex: Solvent effects of the cosubstrate β-mercaptoethanol
-
2 complex: Solvent effects of the cosubstrate β-mercaptoethanol, J. Biol. Chem. 271, 29100-29106.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 29100-29106
-
-
Ahmed, S.A.1
McPhie, P.2
Miles, E.W.3
-
15
-
-
0030029486
-
Allosteric regulation of tryptophan synthase: Effects of pH, temperature, and α-subunit ligands on the equilibrium distribution of pyridoxal-5′-phosphate-L-serine intermediates
-
Peracchi, A., Betatti, S., Mozzarelli, A., Rossi, G. L., Miles, E. W., and Dunn, M. F. (1996) Allosteric regulation of tryptophan synthase: Effects of pH, temperature, and α-subunit ligands on the equilibrium distribution of pyridoxal-5′-phosphate-L-serine intermediates, Biochemistry 35, 1872-1880.
-
(1996)
Biochemistry
, vol.35
, pp. 1872-1880
-
-
Peracchi, A.1
Betatti, S.2
Mozzarelli, A.3
Rossi, G.L.4
Miles, E.W.5
Dunn, M.F.6
-
16
-
-
0000818472
-
Reaction of protonic ionization for buffering agents
-
Kitamura, Y., and Itoh, T. (1987) Reaction of protonic ionization for buffering agents, J. Solution Chem. 16, 715-725.
-
(1987)
J. Solution Chem.
, vol.16
, pp. 715-725
-
-
Kitamura, Y.1
Itoh, T.2
-
17
-
-
0002306568
-
A critical comparison of least absolute deviation fitting (robust) and least-squares fitting: The importance of error distributions
-
Matheson, I. B. C. (1990) A critical comparison of least absolute deviation fitting (robust) and least-squares fitting: The importance of error distributions, Comput. Chem. 14, 49-57.
-
(1990)
Comput. Chem.
, vol.14
, pp. 49-57
-
-
Matheson, I.B.C.1
-
18
-
-
0035951080
-
Role of the chain termini for the folding transition state of the cold shock protein
-
Perl, D., Holtermann, G., and Schmid, F. X. (2001) Role of the chain termini for the folding transition state of the cold shock protein, Biochemistry 40, 15501-15511.
-
(2001)
Biochemistry
, vol.40
, pp. 15501-15511
-
-
Perl, D.1
Holtermann, G.2
Schmid, F.X.3
-
19
-
-
0036303731
-
Water contributes actively to the rapid crossing of a protein unfolded barrier
-
Jacob, M. H., Saudan, C., Holtermann, G., Martin, A., Perl, D., Merbach, A. E., and Schmidt, F. X. (2002) Water contributes actively to the rapid crossing of a protein unfolded barrier, J. Mol. Biol. 318, 837-845.
-
(2002)
J. Mol. Biol.
, vol.318
, pp. 837-845
-
-
Jacob, M.H.1
Saudan, C.2
Holtermann, G.3
Martin, A.4
Perl, D.5
Merbach, A.E.6
Schmidt, F.X.7
-
21
-
-
0015493820
-
Kinetic spectroscopic studies of substrate and subunit interactions of tryptophan synthetase
-
York, S. S. (1972) Kinetic spectroscopic studies of substrate and subunit interactions of tryptophan synthetase, Biochemistry 11, 2733-2740.
-
(1972)
Biochemistry
, vol.11
, pp. 2733-2740
-
-
York, S.S.1
-
23
-
-
0030606789
-
Time-resolved fluorescence of tryptophan synthase
-
Vaccari, S., Benci, S., Peracchi, A., and Mozzarelli, A. (1996) Time-resolved fluorescence of tryptophan synthase, Biophys. Chem. 61, 9-22.
-
(1996)
Biophys. Chem.
, vol.61
, pp. 9-22
-
-
Vaccari, S.1
Benci, S.2
Peracchi, A.3
Mozzarelli, A.4
-
24
-
-
0022344850
-
Detection and identification of intermediates in the reaction of L-serine with Escherichia coli tryptophan synthase via rapid-scanning ultraviolet-visible spectroscopy
-
Drewe, W. F., Jr., and Dunn, M. F. (1985) Detection and identification of intermediates in the reaction of L-serine with Escherichia coli tryptophan synthase via rapid-scanning ultraviolet-visible spectroscopy, Biochemistry 24, 3977-3987.
-
(1985)
Biochemistry
, vol.24
, pp. 3977-3987
-
-
Drewe Jr., W.F.1
Dunn, M.F.2
-
25
-
-
0015228604
-
Kinetic studies of tryptophan synthase. Interaction of L-serine, indole, and tryptophan with the native enzyme
-
Faeder, E. J., and Hammes, G. G. (1971) Kinetic studies of tryptophan synthase. Interaction of L-serine, indole, and tryptophan with the native enzyme, Biochemistry 10, 1041-1045.
-
(1971)
Biochemistry
, vol.10
, pp. 1041-1045
-
-
Faeder, E.J.1
Hammes, G.G.2
-
26
-
-
0020674663
-
The mechanism of binding of L-serine to tryptophan synthase from Escherichia coli
-
Lane, A. N., and Kirschner, K. (1983) The mechanism of binding of L-serine to tryptophan synthase from Escherichia coli, Eur. J. Biochem. 129, 561-570.
-
(1983)
Eur. J. Biochem.
, vol.129
, pp. 561-570
-
-
Lane, A.N.1
Kirschner, K.2
-
27
-
-
0035954399
-
D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity
-
Ferrari, D., Yang, L.-H., Miles, E. W., and Dunn, M. F. (2001) βD305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity, Biochemistry 40, 7421-7432.
-
(2001)
Biochemistry
, vol.40
, pp. 7421-7432
-
-
Ferrari, D.1
Yang, L.-H.2
Miles, E.W.3
Dunn, M.F.4
-
28
-
-
0035478292
-
Pressure provides new insights into protein folding, dynamics, and structure
-
Silva, J. L., Foguel, D., and Royer, C. A. (2001) Pressure provides new insights into protein folding, dynamics, and structure, Trends Biochem. Sci. 26, 612-618.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 612-618
-
-
Silva, J.L.1
Foguel, D.2
Royer, C.A.3
-
29
-
-
0028174289
-
Crystal structures of Escherichia coli aspartate aminotransferase in two conformations. Comparison of an unliganded open and two liganded closed forms
-
Jager, J., Moser M., Sauder U., and Jansonius, J. N. (1994) Crystal structures of Escherichia coli aspartate aminotransferase in two conformations. Comparison of an unliganded open and two liganded closed forms, J. Mol. Biol. 239, 285-305.
-
(1994)
J. Mol. Biol.
, vol.239
, pp. 285-305
-
-
Jager, J.1
Moser, M.2
Sauder, U.3
Jansonius, J.N.4
-
30
-
-
0030800147
-
2 complex with ligands bound to the active sites of the α- And β-subunits reveal ligand-induced conformational changes
-
2 complex with ligands bound to the active sites of the α- and β-subunits reveal ligand-induced conformational changes, Biochemistry 36, 7664-7680.
-
(1997)
Biochemistry
, vol.36
, pp. 7664-7680
-
-
Rhee, S.1
Parris, K.D.2
Hyde, C.C.3
Ahmed, S.A.4
Miles, E.W.5
Davies, D.R.6
-
31
-
-
0023055734
-
Pressure dissociation and conformational drift of the β dimer of tryptophan synthase
-
Silva, J. L., Miles, E. W., and Weber, G. (1986) Pressure dissociation and conformational drift of the β dimer of tryptophan synthase, Biochemistry 25, 5780-5786.
-
(1986)
Biochemistry
, vol.25
, pp. 5780-5786
-
-
Silva, J.L.1
Miles, E.W.2
Weber, G.3
-
32
-
-
0021919108
-
Influence of cofactor pyridoxal 5′-phosphate on reversible high-pressure denaturation of isolated β 2 dimer of tryptophan synthase bienzyme complex from Escherichia coli
-
Seifert, T., Bartholmes, P., and Jaenicke, R. (1985) Influence of cofactor pyridoxal 5′-phosphate on reversible high-pressure denaturation of isolated β 2 dimer of tryptophan synthase bienzyme complex from Escherichia coli, Biochemistry 24, 339-345.
-
(1985)
Biochemistry
, vol.24
, pp. 339-345
-
-
Seifert, T.1
Bartholmes, P.2
Jaenicke, R.3
-
33
-
-
0020001556
-
2-subunit of tryptophan synthase from Escherichia coli after dissociation induced by high hydrostatic pressure. Equilibrium and kinetic studies
-
2-subunit of tryptophan synthase from Escherichia coli after dissociation induced by high hydrostatic pressure. Equilibrium and kinetic studies, Biophys. Chem. 15, 1-8.
-
(1982)
Biophys. Chem.
, vol.15
, pp. 1-8
-
-
Seifert, T.1
Bartholmes, P.2
Jaenicke, R.3
-
35
-
-
0021756303
-
2-dimer of tryptophan synthase from Escherichia coli monitored by sucrose gradient centrifugation
-
2-dimer of tryptophan synthase from Escherichia coli monitored by sucrose gradient centrifugation, FEBS Lett. 173, 381-384.
-
(1984)
FEBS Lett.
, vol.173
, pp. 381-384
-
-
Seifert, T.1
Bartholmes, P.2
Jaenicke, R.3
-
36
-
-
0028986698
-
2-subunits in the bienzyme complex tryptophan synthase from Escherichia coli
-
2-subunits in the bienzyme complex tryptophan synthase from Escherichia coli, Biochemistry 34, 1959-1967.
-
(1995)
Biochemistry
, vol.34
, pp. 1959-1967
-
-
Sindern, S.1
Van Eldik, R.2
Bartholmes, P.3
-
37
-
-
0033214099
-
The effects of hydrostatic pressure on the conformation of plasminogen
-
Kornblatt, J. A., Kornblatt, M. J., Clery, C., and Balny, C. (1999) The effects of hydrostatic pressure on the conformation of plasminogen, Eur. J. Biochem. 265, 120-126.
-
(1999)
Eur. J. Biochem.
, vol.265
, pp. 120-126
-
-
Kornblatt, J.A.1
Kornblatt, M.J.2
Clery, C.3
Balny, C.4
-
38
-
-
0032478214
-
Protein hydration in solution. Experimental observation by X-ray and neutron scattering
-
Svergun, D. I., Richard, S., Koch, M. H. J., Sayers, Z., Kuprin, S., and Zaccai, G. (1998) Protein hydration in solution. Experimental observation by X-ray and neutron scattering, Proc. Natl. Acad. Sci. U.S.A. 95, 2267-2272.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 2267-2272
-
-
Svergun, D.I.1
Richard, S.2
Koch, M.H.J.3
Sayers, Z.4
Kuprin, S.5
Zaccai, G.6
-
39
-
-
0037117502
-
Is the first hydration shell of lysozyme of higher density than bulk water?
-
Merzel, F., and Smith, J. C. (2002) Is the first hydration shell of lysozyme of higher density than bulk water? Proc. Natl. Acad. Sci. U.S.A. 99, 5379-5383.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 5379-5383
-
-
Merzel, F.1
Smith, J.C.2
-
40
-
-
0842342617
-
Estimating hydration changes upon biomolecular reactions from osmotic stress, high pressure, and preferential hydration experiments
-
Shimizu, S. (2003) Estimating hydration changes upon biomolecular reactions from osmotic stress, high pressure, and preferential hydration experiments, Proc. Natl. Acad. Sci. U.S.A. 101, 1195-1199.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 1195-1199
-
-
Shimizu, S.1
-
41
-
-
0347994109
-
Two different proteins that compete for binding to thrombin have opposite kinetic and thermodynamic profiles
-
Baerga-Ortiz, A., Bergqvist, S., Mandell, J. G., and Komives, E. A. (2004) Two different proteins that compete for binding to thrombin have opposite kinetic and thermodynamic profiles, Protein Sci. 13, 166-176.
-
(2004)
Protein Sci.
, vol.13
, pp. 166-176
-
-
Baerga-Ortiz, A.1
Bergqvist, S.2
Mandell, J.G.3
Komives, E.A.4
-
42
-
-
0029941271
-
Energetics of hydrogen bonding in proteins: A model compound study
-
Habermann, S. M., and Murphy, K. P. (1996) Energetics of hydrogen bonding in proteins: A model compound study, Protein Sci. 5, 1229-1239.
-
(1996)
Protein Sci.
, vol.5
, pp. 1229-1239
-
-
Habermann, S.M.1
Murphy, K.P.2
-
43
-
-
0037031307
-
Proton transfers in the β-reaction catalysed by tryptophan synthase
-
Hur, O, Niks, D., Casino, P., and Dunn, M. F. (2002) Proton transfers in the β-reaction catalysed by tryptophan synthase, Biochemistry 41, 9991-10001.
-
(2002)
Biochemistry
, vol.41
, pp. 9991-10001
-
-
Hur, O.1
Niks, D.2
Casino, P.3
Dunn, M.F.4
-
44
-
-
0032478094
-
Mutations in the contact region between the α and β subunits of tryptophan synthase alter subunit interaction and intersubunit communication
-
Rowlett, R., Yang, L. H., Ahmed, S. A., McPhie, P., Jhee, K. H., and Miles E. W. (1998) Mutations in the contact region between the α and β subunits of tryptophan synthase alter subunit interaction and intersubunit communication, Biochemistry 37, 2961-2966.
-
(1998)
Biochemistry
, vol.37
, pp. 2961-2966
-
-
Rowlett, R.1
Yang, L.H.2
Ahmed, S.A.3
McPhie, P.4
Jhee, K.H.5
Miles, E.W.6
-
46
-
-
0027493858
-
2 complex. Critical role of the β subunit lysine 167 in intersubunit communication
-
2 complex. Critical role of the β subunit lysine 167 in intersubunit communication, J. Biol. Chem. 268, 22269-22272.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 22269-22272
-
-
Yang, X.J.1
Miles, E.W.2
-
47
-
-
0017049642
-
The scope of moderate pressure changes for kinetic and equilibrium studies of biochemical systems
-
Davis, J. S., and Gutfreund, H. (1976) The scope of moderate pressure changes for kinetic and equilibrium studies of biochemical systems, FEBS Lett. 72, 199-207.
-
(1976)
FEBS Lett.
, vol.72
, pp. 199-207
-
-
Davis, J.S.1
Gutfreund, H.2
|