Snake venom C-type lectins interacting with platelet receptors. Structure-function relationships and effects on haemostasis

Toxicon

Volumn 45, Issue 8, 2005, Pages 1089-1098

  Lu, Qiumin ^a   Navdaev, Alexey ^a   Clemetson, Jeannine M ^a   Clemetson, Kenneth J ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

C type lectins; Haemostasis; Platelets; Receptors; Snake venom

Indexed keywords

AGGLUCETIN; AGGRETIN; AGKAGGREGIN; AGKICETIN C; AGKISACUTACIN; ALBOAGGREGIN A; ALBOAGGREGIN B; ALBOAGGREGIN C; ALBOLUXIN; BILINEXIN; BINDING PROTEIN; BITISCETIN; BOTHROJARACIN; BOTROCETIN; CONVULXIN; DIAGNOSTIC AGENT; ECHICETIN; EMS16 PROTEIN; FLAVOCETIN A; GLYCOPROTEIN IB; HALYXIN; LEBECETIN; LECTIN; MAMUSHIGIN; MUCETIN; MUCROCETIN; MUROCETIN; OPHIOLUXIN; PURPUREOTIN; RHODOAGGRETIN; RHODOCETIN; RISTOCETIN; SNAKE VENOM; STEJNULXIN; THROMBOCYTE RECEPTOR; TOKARACETIN; UNCLASSIFIED DRUG;

ARTICLE; BERNARD SOULIER DISEASE; BINDING SITE; HEMOSTASIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; SNAKE; STRUCTURE ACTIVITY RELATION; THROMBOCYTE; THROMBOCYTE ACTIVATION; VON WILLEBRAND DISEASE;

AMINO ACID SEQUENCE; ANIMALS; HEMOSTASIS; LECTINS, C-TYPE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PLATELET MEMBRANE GLYCOPROTEINS; SEQUENCE ALIGNMENT; SNAKE VENOMS; SNAKES; STRUCTURE-ACTIVITY RELATIONSHIP; VON WILLEBRAND FACTOR;

EID: 19544368798     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2005.02.022     Document Type: Article

References (66)

1. R.K. Andrews, M.H. Kroll, C.M. Ward, J.W. Rose, R.M. Scarborough, A.I. Smith, J.A. Lopez, and M.C. Berndt Binding of a novel 50-kilodalton alboaggregin from Trimeresurus albolabris and related viper venom proteins to the platelet membrane glycoprotein Ib-IX-V complex. Effect on platelet aggregation and glycoprotein Ib-mediated platelet activation Biochemistry 35 1996 12629 12639 (Abstr.)
2. F. Aragon-Ortiz, J.R. Brenes-Brenes, and F. Gubensek Characterization and properties of a lectin-like protein from Lachesis muta snake venom Toxicon 28 1990 143
3. F. Aragon-Ortiz, R. Mentele, and E.A. Auerswald Amino acid sequence of a lectin-like protein from Lachesis muta stenophyrs venom Toxicon 34 1996 763 769
4. H. Atoda, M. Ishikawa, E. Yoshihara, F. Sekiya, and T. Morita Blood coagulation factor IX-binding protein from the venom of Trimeresurus flavoviridis: Purification and characterization J. Biochem. (Tokyo) 118 1995 965 973
5. T. Batuwangala, M. Leduc, J.M. Gibbins, C. Bon, and E.Y. Jones Structure of the snake-venom toxin convulxin Acta Crystallogr. D Biol. Crystallogr. 60 2004 46 53
6. 1 integrin, glycoprotein VI, and the ligand-binding domain of glycoprotein Ibα J. Biol. Chem. 276 2001 25121 25126
7. Y.L. Chen, and I.H. Tsai Functional and sequence characterization of agkicetin, a new glycoprotein Ib antagonist isolated from Agkistrodon acutus venom Biochem. Biophys. Res. Commun. 210 1995 472 477
8. Y.L. Chen, and I.H. Tsai Functional and sequence characterization of coagulation factor IX/factor X-binding protein from the venom of Echis carinatus leucogaster Biochemistry 35 1996 5264 5271
9. Y.L. Chen, K.W. Tsai, T. Chang, T.M. Hong, and I.H. Tsai Glycoprotein Ib-binding protein from the venom of Deinagkistrodon acutus-cDNA sequence, functional characterization, and three-dimensional modeling Thromb. Haemost. 83 2000 119 126
10. X. Cheng, Y. Qian, Q. Liu, B.X. Li, M. Zhang, and J. Liu Purification, characterization, and cDNA cloning of a new fibrinogenlytic venom protein, Agkisacutacin, from Agkistrodon acutus venom Biochem. Biophys. Res. Commun. 265 1999 530 535
11. C.H. Chung, L.C. Au, and T.F. Huang Molecular cloning and sequence analysis of aggretin, a collagen-like platelet aggregation inducer Biochem. Biophys. Res. Commun. 263 1999 723 727
12. D.D. de Carvalho, S. Marangoni, and J.C. Novello Primary structure characterization of Bothrops jararacussu snake venom lectin J. Protein Chem. 21 2002 43 50
13. D. Dormann, J.M. Clemetson, A. Navdaev, B.E. Kehrel, and K.J. Clemetson Alboaggregin A activates platelets by a mechanism involving glycoprotein VI as well as glycoprotein Ib Blood 97 2001 929 936
14. 1 Thromb. Haemost. 86 2001 1277 1283
15. X.Y. Du, E. Magnenat, T.N. Wells, and K.J. Clemetson Alboluxin, a snake C-type lectin from Trimeresurus albolabris venom is a potent platelet agonist acting via GPIb and GPVI Thromb. Haemost. 87 2002 692 698
16. X.Y. Du, J.M. Clemetson, A. Navdaev, E.M. Magnenat, T.N. Wells, and K.J. Clemetson Ophioluxin, a convulxin-like C-type lectin from Ophiophagus hannah (King cobra) is a powerful platelet activator via glycoprotein VI J. Biol. Chem. 277 2002 35124 35132
17. 2 subunit proximal to the collagen binding site Biochem. J. 15 2003 77 85
18. Y. Fujimura, Y. Ikeda, S. Miura, E. Yoshida, H. Shima, S. Nishida, M. Suzuki, K. Titani, Y. Taniuchi, and T. Kawasaki Isolation and characterization of jararaca GPIb-BP, a snake venom antagonist specific to platelet glycoprotein Ib Thromb. Haemost. 74 1995 743 750
19. K. Fukuda, H. Mizuno, H. Atoda, and T. Morita Crystal structure of flavocetin-A, a platelet glycoprotein Ib-binding protein, reveals a novel cyclic tetramer of C-type lectin-like heterodimers Biochemistry 39 2000 1915 1923
20. K. Fukuda, T.A. Doggett, L.A. Bankston, M.A. Cruz, T.G. Diacovo, and R.C. Liddington Structural basis of von Willebrand factor activation by the snake toxin botrocetin Structure 10 2002 943 950
21. J. Hamako, T. Matsui, M. Suzuki, M. Ito, K. Makita, Y. Fujimura, Y. Ozeki, and K. Titani Purification and characterization of bitiscetin, a novel von Willebrand factor modulator protein from Bitis arietans snake venom Biochem. Biophys. Res. Commun. 226 1996 273 279
22. 2+-dependent-type lectins J. Biol. Chem. 266 1991 2320 2326
23. S. Hirotsu, H. Mizuno, K. Fukuda, M.C. Qi, T. Matsui, J. Hamako, T. Morita, and K. Titani Crystal structure of bitiscetin, a von Willebrand factor-dependent platelet aggregation inducer Biochemistry 40 2001 13592 13597
24. K. Horii, D. Okuda, T. Morita, and H. Mizuno Structural characterization of EMS16, an antagonist of collagen receptor (GPIa/IIa) from the venom of Echis multisquamatus Biochemistry 42 2003 12497 12502
25. K.F. Huang, T.P. Ko, C.C. Hung, J. Chu, A.H. Wang, and S.H. Chiou Crystal structure of a platelet-agglutinating factor isolated from the venom of Taiwan habu (Trimeresurus mucrosquamatus) Biochem. J. 378 Pt 2 2004 399 407
26. S. Kanaji, T. Kanaji, K. Furihata, K. Kato, J.L. Ware, and T.J. Kunicki Convulxin binds to native, human glycoprotein Ibα J. Biol. Chem. 278 2003 39452 39460
27. T. Kawasaki, Y. Taniuchi, N. Hisamichi, Y. Fujimura, M. Suzuki, K. Titani, Y. Sakai, S. Kaku, N. Satoh, and T. Takenaka Tokaracetin, a new platelet antagonist that binds to platelet glycoprotein Ib and inhibits von Willebrand factor-dependent shear-induced platelet aggregation Biochem. J. 308 Pt 3 1995 947 953
28. T. Kawasaki, Y. Fujimura, Y. Usami, M. Suzuki, S. Miura, Y. Sakurai, K. Makita, Y. Taniuchi, K. Hirano, and K. Titani Complete amino acid sequence and identification of the platelet glycoprotein Ib-binding site of jararaca GPIb-BP, a snake venom protein isolated from Bothrops jararaca J. Biol. Chem. 271 1996 10635 10639
29. B.H. Koo, Y.D. Sohn, K.C. Hwang, Y. Jang, D.S. Kim, and K.H. Chung Characterization and cDNA cloning of halyxin, a heterogeneous three-chain anticoagulant protein from the venom of Agkistrodon halys brevicaudus Toxicon 40 2002 947 957
30. M.A. Kowalska, L. Tan, J.C. Holt, M. Peng, J. Karczewski, J.J. Calvete, and S. Niewiarowski Alboaggregins A and B. Structure and interaction with human platelets Thromb. Haemost. 79 1998 609 613
31. M. Leduc, and C. Bon Cloning of subunits of convulxin, a collagen-like platelet-aggregating protein from Crotalus durissus terrificus venom Biochem. J. 333 Pt 2 1998 389 393
32. W.H. Lee, and Y. Zhang Molecular cloning and characterization of a platelet glycoprotein Ib-binding protein from the venom of Trimeresurus stejnegeri Toxicon 41 2003 885 892
33. W.H. Lee, XY Du, QM Lu, KJ Clemetson, and Y Zhang Stejnulxin, a novel snake C-type lectin-like protein from Trimeresurus stejnegeri venom is a potent platelet agonist acting specifically via GPVI Thromb. Haemost. 90 2003 662 671
34. W.H. Lee, Q.Y. Zhuang, and Y. Zhang Cloning and characterization of a blood coagulation factor IX-binding protein from the venom of Trimeresurus stejnegeri Toxicon 41 2003 765 772
35. X. Li, L. Zheng, C. Kong, P.R. Kolatkar, and M.C. Chung Purpureotin: a novel di-dimeric C-type lectin-like protein from Trimeresurus purpureomaculatus venom is stabilized by noncovalent interactions Arch. Biochem. Biophys. 424 2004 53 62
36. S. Liu, Z. Zhu, J. Sun, Z. Zhu, Q. Huang, M. Teng, and L. Niu Purification, crystallization and preliminary X-ray crystallographic analysis of agkaggregin, a C-type lectin-like protein from Agkistrodon acutus venom Acta. Crystallogr. D Biol. Crystallogr. 58 Pt 4 2002 675 678
37. Q.M. Lu, A. Navdaev, J.M. Clemetson, and K.J. Clemetson GPIb is involved in platelet aggregation induced by mucetin, a snake C-type lectin protein from Chinese habu (Trimeresurus mucrosquamatus) venom Thromb. Haemost. 91 6 2004 1168 1176
38. N. Maita, K. Nishio, E. Nishimoto, T. Matsui, Y. Shikamoto, T. Morita, JE. Sadler, and H. Mizuno Crystal structure of von Willebrand factor A1 domain complexed with snake venom, bitiscetin: insight into glycoprotein Ibα binding mechanism induced by snake venom proteins J. Biol. Chem. 278 2003 37777 37781
39. 1 integrin Biochemistry 39 2000 9859 9867
40. H. Mizuno, Z. Fujimoto, M. Koizumi, H. Kano, H. Atoda, and T. Morita Crystal structure of coagulation factor IX-binding protein from habu snake venom at 2.6 A: implication of central loop swapping based on deletion in the linker region J. Mol. Biol. 289 1999 103 112
41. a-accelerated prothrombin activation Thromb. Haemost. 87 2002 288 293
42. R.Q. Monteiro, P.E. Bock, M.L. Bianconi, and R.B. Zingali Characterization of bothrojaracin interaction with human prothrombin Protein Sci. 10 2001 1897 1904
43. M.T. Murakami, S.P. Zela, L.M. Gava, S. Michelan-Duarte, A.C. Cintra, and R.K. Arni Crystal structure of the platelet activator convulxin, a disulfide-linked alpha4beta4 cyclic tetramer from the venom of Crotalus durissus terrificus Biochem. Biophys. Res. Commun. 310 2003 478 482
44. 1 integrin and glycoprotein Ib, activating Syk and phospholipase Cγ 2, but does not involve the glycoprotein VI/Fc receptor γ chain collagen receptor J. Biol. Chem. 276 2001 20882 20889
45. A. Navdaev, D. Dormann, J.M. Clemetson, and K.J. Clemetson Echicetin, a GPIb-binding snake C-type lectin from Echis carinatus, also contains a binding site for IgMκ responsible for platelet agglutination in plasma and inducing signal transduction Blood 97 2001 2333 2341
46. T. Nikai, J. Suzuki, Y. Komori, M. Ohkura, Y. Ohizumi, and H. Sugihara Primary structure of the lectin from the venom of Bitis arietans (puff-adder) Biol. Pharm. Bull. 18 1995 1620 1622
47. J. Polgar, J.M. Clemetson, B.E. Kehrel, M. Wiedemann, E.M. Magnenat, T.N. Wells, and K.J. Clemetson Platelet activation and signal transduction by convulxin, a C-type lectin from Crotalus durissus terrificus (tropical rattlesnake) venom via the p62/GPVI collagen receptor J. Biol. Chem. 272 1997 13576 13583
48. J. Polgar, E.M. Magnenat, M.C. Peitsch, T.N. Wells, M.S. Saqi, and K.J. Clemetson Amino acid sequence of the alpha subunit and computer modelling of the alpha and beta subunits of echicetin from the venom of Echis carinatus (saw-scaled viper) Biochem. J. 323 Pt 2 1997 533 537
49. Y. Sakurai, Y. Fujimura, T. Kokubo, K. Imamura, T. Kawasaki, M. Handa, M. Suzuki, T. Matsui, K. Titani, and A. Yoshioka The cDNA cloning and molecular characterization of a snake venom platelet glycoprotein Ib-binding protein, mamushigin, from Agkistrodon halys blomhoffii venom Thromb. Haemost. 79 1998 1199 1207
50. S. Sarray, N. Srairi, J. Luis, J. Marvaldi, M. El Ayeb, and N. Marrakchi Lebecetin, a C-lectin protein from the venom of Macrovipera lebetina that inhibits platelet aggregation and adhesion of cancerous cells Haemostasis 31 2001 173 176
51. S. Sarray, N. Srairi, M. Hatmi, J. Luis, H. Louzir, I. Regaya, H. Slema, J. Marvaldi, M. El Ayeb, and N. Marrakchi Lebecetin, a potent antiplatelet C-type lectin from Macrovipera lebetina venom Biochim. Biophys. Acta. 1651 2003 30 40
52. S. Sarray, V. Berthet, J.J. Calvete, J. Secchi, J. Marvaldi, M.E. Ayeb, N. Marrakchi, and J. Luis Lebectin, a novel C-type lectin from Macrovipera lebetina venom, inhibits integrin-mediated adhesion, migration and invasion of human tumour cells Lab. Invest. 84 2004 573 581
53. F. Sekiya, H. Atoda, and T. Morita Isolation and characterization of an anticoagulant protein homologous to botrocetin from the venom of Bothrops jararaca Biochemistry 32 1993 6892 6897
54. U. Sen, S. Vasudevan, G. Subbarao, R.A. McClintock, R. Celikel, Z.M. Ruggeri, and K.I. Varughese Crystal structure of the von Willebrand factor modulator botrocetin Biochemistry 40 2001 345 352
55. Y. Shin, I. Okuyama, J. Hasegawa, and T. Morita Molecular cloning of glycoprotein Ib-binding protein, flavocetin-A, which inhibits platelet aggregation Thromb. Res. 99 2000 239 247
56. Y. Taniuchi, T. Kawasaki, Y. Fujimura, M. Suzuki, K. Titani, Y. Sakai, S. Kaku, N. Hisamichi, N. Satoh, and T. Takenaka Flavocetin-A and -B, two high molecular mass glycoprotein Ib binding proteins with high affinity purified from Trimeresurus flavoviridis venom, inhibit platelet aggregation at high shear stress Biochim. Biophys. Acta. 1244 1995 331 338
57. Y. Usami, Y. Fujimura, M. Suzuki, Y. Ozeki, K. Nishio, H. Fukui, and K. Titani Primary structure of two-chain botrocetin, a von Willebrand factor modulator purified from the venom of bothrops jararaca Proc. Natl. Acad. Sci. USA 9 1993 928 932
58. J.R. Walker, B. Nagar, N.M. Young, T. Hirama, and J.M. Rini X-ray crystal structure of a galactose-specific C-type lectin possessing a novel decameric quaternary structure Biochemistry 43 2004 3783 3792
59. R. Wang, R.M. Kini, and M.C. Chung Rhodocetin, a novel platelet aggregation inhibitor from the venom of Calloselasma rhodostoma (Malayan pit viper): synergistic and noncovalent interaction between its subunits Biochemistry 38 1999 7584 7593
60. R. Wang, C. Kong, P. Kolatkar, and M.C. Chung A novel dimer of a C-type lectin-like heterodimer from the venom of Calloselasma rhodostoma (Malayan pit viper) FEBS Lett. 508 2001 447 453
61. W.J. Wang, Q.D. Ling, M.Y. Liau, and T.F. Huang A tetrameric glycoprotein Ib-binding protein, agglucetin, from Formosan pit viper: Structure and interaction with human platelets Thromb. Haemost. 90 2003 465 475
62. Q. Wei, Q.M. Lu, Y. Jin, R. Li, J.F. Wei, W.Y. Wang, and Y.L. Xiong Purification and cloning of a novel C-type lectin-like protein with platelet aggregation activity from Trimeresurus mucrosquamatus venom Toxicon 40 2002 1331 1338
63. X. Xu, Q. Liu, Y. Xie, and S. Wu Purification and characterization of anticoagulation factors from the venom of Agkistrodon acutus Toxicon 38 2000 1517 1528
64. Q. Xu, X.F. Wu, Q.C. Xia, and K.Y. Wang Cloning of a galactose-binding lectin from the venom of Trimeresurus stejnegeri Biochem. J. 341 Pt 3 1999 733 737
65. J. Zang, M. Teng, and L. Niu Purification, crystallization and preliminary crystallographic analysis of AHP IX-bp, a zinc ion and pH-dependent coagulation factor IX binding protein from Agkistrodon halys Pallas venom Acta Crystallogr. D Biol. Crystallogr. 59 Pt 4 2003 730 733
66. R.B. Zingali, M. Jandrot-Perrus, M.C. Guillin, and C. Bon Bothrojaracin, a new thrombin inhibitor isolated from Bothrops jararaca venom: characterization and mechanism of thrombin inhibition Biochemistry 32 1993 10794 10802