Alboaggregin A activates platelets by a mechanism involving glycoprotein VI as well as glycoprotein Ib

Blood

Volumn 97, Issue 4, 2001, Pages 929-936

  Dormann D ^a   Clemetson, J M ^a   Navdaev, A ^a   Kehrel, B E ^a   Clemetson, K J ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALBOAGGREGIN A; GLYCOPROTEIN; GLYCOPROTEIN IB; SNAKE VENOM; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARTICLE; CELL LYSATE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SNAKE; THROMBOCYTE ACTIVATION;

EID: 0035865596     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V97.4.929     Document Type: Article

References (33)

1. Characterization of snake venom components acting on blood coagulation and platelet function
2. Snake venom modulators of platelet adhesion receptors and their ligands
3. Actions of some coagulant snake venoms on blood platelets
4. Snake venom proteases affecting hemostasis and thrombosis
5. Viper venom disintegrins and related molecules
6. What have snakes told us about integrins?
7. Snake venom hemorrhagins
8. Primary structure of two-chain botrocetin, a von Willebrand factor modulator purified from the venom of Bothrops jararaca
9. Echicetin: A snake venom protein that inhibits binding of yon Willebrand factor and alboaggregins to platelet glycoprotein lb
10. Bothrojaracin, a new thrombin inhibitor isolated from Bothrops jararaca venom: Characterization and mechanism of thrombin inhibition
11. Tokaracetin, a new platelet antagonist that binds to platelet glycoprotein lb and inhibits von Willebrand factor-dependent shear-induced platelet aggregation
12. Complete amino acid sequence and identification of the platelet glycoprotein lb-binding site of jararaca GPlb-BP, a snake venom protein isolated from Bothrops jararaca
13. Glycoprotein lb-binding protein from the venom of Deinagkistrodon acutus - cDNA sequence, funcional characterization, and three-dimensional modeling
14. Binding of a novel 50-kilodalton alboaggregin from Trimeresurus albolabris and related viper venom proteins to the platelet membrane glycoprotein lb-IX-V complex. Effect on platelet aggregation and glycoprotein lb-mediated platelet activation
15. Alboaggregin-B: A new platelet agonist that binds to platelet membrane glycoprotein lb
16. Flavocelin-A and -B, two high molecular mass glycoprotein lb binding proteins with high affinity purified from Trimeresurus flavoviridis venom, inhibit platelet aggregation at high shear stress
17. Platelet activation and signal transduction by convulxin, a C-type lectin from Crotalus durissus terrificus (tropical rattlesnake) venom via the p62/GPVI collagen receptor
18. Adhesion and activation of human platelets induced by convulxin involve glycoprotein VI and integrin α2β1
19. Aggretin, a novel platelet-aggregation inducer from snake (Calloselasma rhodostoma) venom, activates phospholipase C by acting as a glycoprotein la/lla agonist
20. Crystal structure of coagulation factor IX-binding protein from habu snake venom at 2.6 A: Implication of central loop swapping based on deletion in the linker region
21. Crystal structure of flavocetin-A, a platelet glycoprotein lb-binding protein, reveals a novel cyclic tetramer of C-type lectin-like heterodimers
22. Alboaggregins A and B. Structure and interaction with human platelets
23. Alboaggregin-B and botrocetin, two snake venom proteins with highly homologous amino acid sequences but totally distinct functions on von Willebrand factor binding to platelets
24. Glycoprotein lb-V-IX, a receptor for von Willebrand factor, couples physically and functionally to the Fc receptor γ chain, Fyn, and Lyn to activate human platelets
25. Isolation and characterization of glycoprotein lb
26. The platelet collagen receptor glycoprotein VI is a member of the immunoglobulin superfamily closely related to FcαR and the natural killer receptors
27. Amino acid sequence of the α subunit and computer modelling of the α and β subunits of echicetin from the venom of Echis carinatus (saw-scaled viper)
28. Isolation of human platelets by albumin gradient and gel filtration
29. The GPlb thrombin-binding site is essential for thrombin-induced platelet procoagulant activity
30. + responses
31. Function of glycoprotein VI and integrin α2β1 in the procoagulant response of single, collagen-adherent platelets
32. Fibrin-dependent platelet procoagulant activity requires GPlb receptors and von Willebrand factor
33. A collagen-like peptide stimulates tyrosine phosphorylation of syk and phospholipase C γ2 in platelets independent of the integrin α2β1