Structural Basis of von Willebrand Factor Activation by the Snake Toxin Botrocetin

Structure

Volumn 10, Issue 7, 2002, Pages 943-950

  Fukuda, Koichi ^a   Doggett, Teresa A ^b   Bankston, Laurie A ^a   Cruz, Miguel A ^c   Diacovo, Thomas G ^b   Liddington, Robert C ^a  

^a BURNHAM INSTITUTE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

A1 domain; Activation; Gain of function; Platelet adhesion; Von Willebrand factor

Indexed keywords

BOTROCETIN; SNAKE VENOM; VON WILLEBRAND FACTOR; MUTANT PROTEIN;

ARTICLE; CELL ADHESION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; GENETICS; HUMAN; IN VITRO STUDY; MUTATION; PHYSIOLOGY; PROTEIN CONFORMATION; THROMBOCYTE; X RAY CRYSTALLOGRAPHY; ALLOSTERISM; BINDING AFFINITY; BLOOD CLOTTING; COMPLEX FORMATION; CRYSTAL STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; THROMBOCYTE ADHESION; WILD TYPE;

BLOOD PLATELETS; CELL ADHESION; CROTALID VENOMS; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; VON WILLEBRAND FACTOR; HUMAN; IN VITRO; SUPPORT, U.S. GOV'T, P.H.S.;

SERPENTES;

EID: 0036070519     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(02)00787-6     Document Type: Article

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