Possible role of procathepsin D in human cancer

Folia Microbiologica

Volumn 50, Issue 1, 2005, Pages 71-76

  Vashishta, A ^a   Fusek, M ^b   Vetvicka V ^a  

^a University of Louisville School of Medicine   (United States)

^b INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 19444372775     PISSN: 00155632     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02931296     Document Type: Article

References (46)

1. BAZZETT L.B., WATKINS C.S., GERCEL-TAYLOR C., TAYLOR D.D.: Modulation of proliferation and chemosensitivity by procathepsin D and its peptides in ovarian cancer. Gynecol. Oncol. 74, 181-187 (1999).
2. BENEŠ P., KOELSCH G., DVOŘÁK B., FUSEK M., VĚTVIČKA V.: Detection of procathepsin D in rat milk. Comp.Biochem.Physiol. B 133, 113-118 (2002).
3. BROUILLET J.P., DUFOUR F., LEMAMY G., GARCIA M., SCHLUP N., GRENIER J., MANI J.C., ROCHEFORT H.: Increased cathepsin D level in the serum of patients with metastatic breast carcinoma detected with a specific pro-cathepsin D immunoassay. Cancer 79, 2132-2136 (1997).
4. CAVAILLES V., AUGREAU P., ROCHEFORT H.: Cathepsin D gene is controlled by a mixed promoter, and estrogens stimulate only TATA-dependent transcription in breast cancer cells. Proc.Nat.Acad.Sci. USA 90, 203-207 (1993).
5. CHAMBON M., REBILLARD X., ROCHEFORT H., BROUILLET J.P., BALDET P., GUITER J., MAUDELONDE T.: Cathepsin D cytosolic assay and immunohistochemical quantification in human prostate tumors. Prostate 24, 320-325 (1994).
6. CHINNI S.R., GERCEL-TAYLOR C., CONNER G.E., TAYLOR D.D.: Cathepsin D antigenic epitopes identified by the humoral responses of ovarian cancer patients. Cancer Immunol.Immunother. 46, 48-54 (1998).
7. ELANGOVAN S., MOULTON B.C.: Blastocyst implantation in the rat and the immunohistochemical distribution and rate of synthesis of uterine lysosomal cathepsin D. Biol.Reprod. 23, 663-668 (1980).
8. FERRANDINA G., SCAMBIA G., PANICI P., ALAMDORI G., PALUDETTI G., CADONI G., DISTEFANO M., MAURIZI M., MANCUSO S.: Cathepsin D in primary squamous laryngeal tumors: correlation with clinico-pathological parameters and receptor status. Cancer Lett. 67, 133-138 (1992).
9. FREUDENHEIM J.L., MARSHALL J.R., GRAHAM S., LAUGHLIN R., VENA J.E., BANDERA E., MUTI P., SWANSON M., NEMOTO T.: Exposure to breastmilk in infancy and the risk of breast cancer. Epidemiology 5, 324-331 (1994).
10. FUSEK M., VĚTVIČKA V.: Mitogenic function of human procathepsin D: the role of the propeptide. Biochem.J. 303, 775-780 (1994).
11. FUSEK M., VĚTVIČKA V.: Aspartic Proteinases: Physiology and Pathology. CRC Press, Boca Raton 1995.
12. GARCIA M., DERCOQ D., PUJOL P., ROCHEFORT H.: Overexpression of transfected cathepsin D in transformed cells increases their malignant phenotype and metastatic potency. Oncogene 5, 1809-1814 (1990).
13. GLONDU M., COOPMAN P., LAURENT-MATHA V., GARCIA M., ROCHEFORT H., LIAUDET-COOPMAN E.: A mutated cathepsin-D devoid of its catalytic activity stimulates the growth of cancer cells. Oncogene 20, 6920-6929 (2001).
14. GLONDU M., LIAUDET-COOPMAN E., DEROCQ D., PLATET N., ROCHEFORT H., GARCIA M.: Down-regulation of cathepsin-D expression by antisense gene transfer inhibits tumor growth and experimental lung metastasis of human breast cancer cells. Oncogene 21, 5127-5134 (2002).
15. HUET G., ZERIMECH F., DIEU M.C., HEMON B., GRARD G., BALDUYCK M., JANIN A., LAFYATIS R., DEGAND P.: The state of differentiation of HT-29 colon carcinoma cells alters the secretion of cathepsin D and of plasminogen activator. Internat.J.Cancer 57, 875-882 (1994).
16. JOHNSON M.D., TORRI J.A., LIPPMAN M.E., DICKSON R.B.: The role of cathepsin D in the invasiveness of human breast cancer cells. Cancer Res. 53, 873-877 (1993).
17. KOELSCH G., METCALF P., VĚTVIČKA V., FUSEK M., p. 273 in Aspartic Proteinases: Structure, Function, Biology, and Biomedical Implications (K. Takahashi, Ed.). Plenum Press, New York 1995.
18. KUTE T.E., SHAO Z.M., SUGG N.K., LONG R.T., RUSSELL G.B., CASE D.: Cathepsin D as a prognostic indicator for node-negative breast cancer patients using both immunoassays and enzymatic assays. Cancer Res. 52, 5198-5203 (1992).
19. LAH T.T., CALAF G., KALMAN E., SHINDE B.G., RUSSO J., JAROSZ D., ZABRECKY J., SOMERS R., DASKAL I.: Cathepsins D, B and L in breast carcinoma and in transformed human breast epithelial cells (HBEC). Biol.Chem.Hoppe-Seyler 376, 357-363 (1995).
20. LARSEN L.B., BOISEN A., PETERSEN T.E.: Procathepsin D cannot autoactivate to cathepsin D at acid pH. FEBS Lett. 319, 54-58 (1993).
21. LAURY-KLEINTOP L.D., CORONEL E.C., LANGE M.K., TACHOVSKY T., LONGO S., TUCKER S., ALHADEFF J.A.: Western blotting and isoform analysis of cathepsin D from normal and malignant human breast cell lines. Breast Cancer Res. Treat. 35, 211-220 (1995).
22. LETO G., GEBBIA N., RAUSA L., TUMMINELLO F.M.: Cathepsin D in the malignant progression of neoplastic diseases. Anticancer Res. 12, 235-240 (1992).
23. LETO G., TUMMINELLO F.M., CRESCIMANNO M., FLANDINA C., GEBBIA N.: Cathepsin D expression levels in nongynecological solid tumors: clinical and therapeutic implications. Clin.Exp.Metastasis 21, 91-106 (2004).
24. METAYE T., MILLET C., KRAIMPS J.L., AUBOUIN B., BARBIER J., BEGON F.: Estrogen receptors and cathepsin D in human thyroid tissue. Cancer 72, 1991-1996 (1993).
25. METCALF P., FUSEK M.: Two crystal structures for cathepsin D: the lysosomal targeting signal and active site. EMBO J. 12, 1293-1302 (1993).
26. NAZEER T., CHURCH K., AMATO C., AMBROS R.A., ROSANO T.G., MALFETANO J.H., ROSS J.S.: Comparative quantitative immunohistochemical and immunoradiometric determinations of cathepsin D in endometrial adenocarcinoma: predictors of tumor aggressiveness. Modern Pathol. 7, 469-474 (1994).
27. PARKER L.: Breast-feeding and cancer prevention. Eur.J.Cancer 37, 155-158 (2001).
28. PODHAJCER O.L., BOVER L., BRAVO A.L., LEDDA M.F., KAIRIYAMA C., CALB I., GUERRA L., CAPONY F., MORDOH J.: Expression of cathepsin D in primary and metastatic human melanoma and dysplastic nevi. J.Invest.Dermatol. 104, 340-344 (1995).
29. PUJOL P., MAUDELONDE T., DAURES J.P., ROUANET P., BROUILLET J.P., PUJOL H., ROCHEFORT H.: A prospective study of the prognostic value of cathepsin D levels in breast cancer cytosol. Cancer 71, 2006-2012 (1993).
30. REID W.A., VALLOR M.J., KAY J.: Immunolocalization of cathepsin D in normal and neoplastic human tissues. J.Clin.Pathol. 39, 1323-1330 (1986).
31. ROCHEFORT H., CAPONY F., GARCIA M., CAVAILLES V., FREISS G., CHAMBON M., MORISSET M., VIGNON F.: Estrogen-induced lysosomal proteases secreted by breast cancer cells: a role in carcinogenesis? J.Cell.Biochem. 35, 17-29 (1987).
32. ROCHEFORT H.: Cathepsin D in breast cancer: a tissue marker associated with metastasis. Eur.J.Cancer 28A, 1780-1783 (1992a).
33. ROCHEFORT H.: Biological and clinical significance of cathepsin D in breast cancer. Acta Oncol. 31, 125-130 (1992b).
34. ROCHEFORT H.: Estrogen-induced genes in breast cancer, and their medical importance. Bull.Acad.Nat.Med. 183, 955-968 (1999).
35. SCHULTZ D.C., BAZEL S., WRIGHT L.M., TUCKER S., LANGE M.K., TACHOVSKY T., LONGO S., NIEDBALA S., ALHADEFF J.A.: Western blotting and enzymatic activity analysis of cathepsin D in breast tissue and sera of patients with breast cancer and benign breast disease and of normal controls. Cancer Res. 54, 48-54 (1994).
36. SPYRATOS F., BROUILLET J.P., DEFRENNE A., HACENE K., ROUESSE J., MAUDELONDE T., BRUNET M., ANDRIEU C., DESPLACES A., ROCHEFORT H.: Cathepsin D: an independent prognostic factor for metastasis of breast cancer. Lancet 2, 1115-1118 (1989).
37. TANG J., WONG R.N.S.: Evolution in the structure and function of aspartic proteases. J.Cell.Biochem. 33, 53-63 (1987).
38. TAYLOR D.D., GERCEL-TAYLOR C.: Tumor-reactive immunoglobulins in ovarian cancer: diagnostic and therapeutic significance? Oncol.Rep. 5, 1519-1524 (1998).
39. TEDONE T., CORREALE M., BARBADOSSA G., CASAVOLA V., PARADISO A., RESHKIN S.J.: Release of the aspartyl protease cathepsin D is associated with and facilitates human breast cancer cell invasion. FASEB J. 11, 785-792 (1997).
40. VĚTVIČKA V., VAGNER J., BAUDYŠ M., TANG J., FOUNDLING S.I., FUSEK M.: Human breast milk contains procathepsin-D detection by specific antibodies. Biochem.Mol.Biol.Internat. 30, 921-928 (1993).
41. VĚTVIČKA V., VĚTVIČKOVÁ J., HILGERT I., VOBŮRKA Z., FUSEK M.: Analysis of the interaction of procathepsin D activation peptide with breast cancer cells. Internat.J.Cancer 73, 403-409 (1997).
42. VĚTVIČKA V., VĚTVIČKOVÁ J., FUSEK M.: Effect of procathepsin D and its activation peptide on prostate cancer cells. Cancer Lett. 129, 55-59 (1998).
43. VĚTVIČKA V., VĚTVIČKOVÁ J., FUSEK M.: Anti-human procathepsin D activation peptide antibodies inhibit breast cancer development. Breast Cancer Res.Treat. 57, 261-269 (1999)
44. VĚTVIČKA V., VĚTVIČKOVÁ J., FUSEK M.: Role of procathepsin D activation peptide in prostate cancer growth. Prostate 44, 1-7 (2000).
45. VĚTVIČKA V., BENEŠ P., FUSEK M.: Procathepsin D in breast cancer: what do we know? Effects of ribozymes and other inhibitors. Cancer Gene Ther. 9, 854-863 (2002).
46. WESTLEY B., ROCHEFORT H.: A secreted glycoprotein induced by estrogen in human breast cancer cell lines. Cell 20, 353-362 (1980).