A new regulator linking quorum sensing and iron uptake in Pseudomonas aeruginosa

Microbiology

Volumn 150, Issue 4, 2004, Pages 752-756

  Cornelis, Pierre ^a   Aendekerk, Séverine ^a  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; ELASTASE; HEMOLYSIN; HOMOSERINE; LACTONE; LYASE; OXIDOREDUCTASE; PEPTIDASE; PROTEINASE; PYOVERDINE; REGULATOR PROTEIN; SIDEROPHORE; SYNTHETASE; VIRULENCE FACTOR;

GENE EXPRESSION REGULATION; IRON METABOLISM; IRON TRANSPORT; NONHUMAN; NOTE; OPEN READING FRAME; PRIORITY JOURNAL; PROMOTER REGION; PSEUDOMONAS AERUGINOSA; REGULON; TRANSCRIPTION REGULATION;

PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 1942505825     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.27086-0     Document Type: Note

References (33)

1. Albus, A. M., Pesci, E. C., Runyen-Janecky, L. J., West, S. E. & Iglewski, B. H. (1997). Vfr controls quorum sensing in Pseudomonas aeruginosa. J Bacteriol 179, 3928-3935.
2. Arevalo-Ferro, C., Hentzer, M., Reil, G., Gorg, A., Kjelleberg, S., Givskov, M., Riedel, K. & Eberl, L. (2003). Identification of quorum-sensing regulated proteins in the opportunistic pathogen Pseudomonas aeruginosa by proteomics. Environ Microbiol 5, 1350-1359.
3. Cámara, M., Williams, P. & Hardman, A. (2002). Controlling infection by tuning in and turning down the volume of bacterial small-talk. Lancet Infect Dis 2, 667-676.
4. Cao, H., Baldini, R. L. & Rahme, L. G. (2001a). Common mechanisms for pathogens of plants and animals. Annu Rev Phytopathol 39, 259-284.
5. Cao, H., Krishnan, G., Goumnerov, B., Tsongalis, J., Tompkins, R. & Rahme, L. G. (2001b). A quorum sensing-associated virulence gene of Pseudomonas aeruginosa encodes a LysR-like transcription regulator with a unique self-regulatory mechanism. Proc Natl Acad Sci U S A 98, 14613-14618.
6. Chugani, S. A., Whiteley, M., Lee, K. M., D'Argenio, D., Manoil, C. & Greenberg, E. P. (2001). QscR, a modulator of quorum-sensing signal synthesis and virulence in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A 98, 2752-2757.
7. D'Argenio, D. A., Calfee, M. W., Rainey, P. B. & Pesci, E. C. (2002). Autolysis and autoaggregation in Pseudomonas aeruginosa colony morphology mutants. J Bacteriol 184, 6481-6489.
8. de Kievit, T. R. & Iglewski, B. H. (2000). Bacterial quorum sensing in pathogenic relationships. Infect Immun 68, 4839-4849.
9. de Kievit, T., Seed, P. C., Nezezon, J., Passador, L. & Iglewski, B. H. (1999). RsaL, a novel repressor of virulence gene expression in Pseudomonas aeruginosa. J Bacteriol 181, 2175-2184.
10. Déziel, E., Lépine, F., Milot, S., He, J., Mindrinos, M. N., Tompkins, R. G. & Rahme, L. G. (2004). Analysis of Pseudomonos aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication. Proc Natl Acad Sci U S A 101, 1339-1344.
11. Diggle, S. P., Winzer, K., Lazdunski, A., Williams, P. & Cámara, M. (2002). Advancing the quorum in Pseudomonas aeruginosa: MvaT and the regulation of N-acylhomoserine lactone production and virulence gene expression. J Bacteriol 184, 2576-2586.
12. Diggle, S. P., Winzer, K., Chhabra, S. R., Worrall, K. E., Cámara, M. & Williams, P. (2003). The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density-dependency of the quorum sensing hierarchy, regulates rhl-dependent genes at the onset of stationary phase and can be produced in the absence of LasR. Mol Microbiol 50, 29-43.
13. Fuqua, C., Wynans, S. C. & Greenberg, E. P. (1996). Census and consensus in bacterial ecosystems: the LuxR-LuxI family of quorum-sensing transcriptional regulators. Annu Rev Microbiol 50, 727-751.
14. Gallagher, L. A., McKnight, S. L., Kuznetsova, M. S., Pesci, E. C. & Manoil, C. (2002). Functions required for extracellular quinolone signaling by Pseudomonas aeruginosa. J Bacteriol 184, 6472-6480.
15. Hentzer, M. & Givskov, M. (2003). Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections. J Clin Invest 112, 1300-1307.
16. Hentzer, M., Wu, H., Andersen, J. B. & 15 other authors (2003). Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J 22, 3803-3815.
17. Juhas, M., Wiehlmann, L., Huber, B. & 8 other authors (2004). Global regulation of quorum sensing and virulence by VqsR in Pseudomonas aeruginosa. Microbiology 150, 831-841.
18. Lamont, I. L., Beare, P. A., Ochsner, U., Vasil, A. I. & Vasil, M. L. (2002). Siderophore mediated signalling regulates virulence factor production in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A 99, 7072-7077.
19. McKnight, S. L., Iglewski, B. H. & Pesci, E. C. (2000). The Pseudomonas quinolone signal regulates rhl quorum sensing in Pseudomonas aeruginosa. J Bacteriol 182, 2702-2708.
20. Ochsner, U. A., Wilderman, P. J., Vasil, A. I. & Vasil, M. L. (2002). GeneChip® expression analysis of the iron starvation response in Pseudomonas aeruginosa: identification of novel pyoverdine biosynthesis genes. Mol Microbiol 45, 1277-1287.
21. Palma, M., Worgall, S. & Quadri, L. E. N. (2003). Transcriptome analysis of the Pseudomonas aeruginosa response to iron. Arch Microbiol 180, 374-379.
22. Pesci, E. C., Milbank, J. B. J., Pearson, J. P., McKnight, S., Kende, A. S., Greenberg, E. P. & Iglewski, B. H. (1999). Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A 96, 11229-11234.
23. Ravel, J. & Cornelis, P. (2003). Genomics of pyoverdine-mediated iron uptake in pseudomonads. Trends Microbiol 11, 195-200.
24. Reimmann, C., Beyeler, M., Latifi, A., Winteler, H., Foglino, M., Lazdunski, A. & Haas, D. (1997). The global activator GacA of Pseudomonas aeruginosa PAO positively controls the production of the autoinducer N-butyryl-homoserine lactone and the formation of the virulence factors pyocyanin, cyanide, and lipase. Mol Microbiol 24, 309-319.
25. Schuster, M., Lostroh, C. P., Ogi, T. & Greenberg, E. P. (2003). Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis. J Bacteriol 185, 2066-2079.
26. Schuster, M., Hawkins, A. C., Harwood, C. S. & Greenberg, E. P. (2004). The Pseudomonas aeruginosa RpoS regulon and its relationship to quorum sensing. Mol Microbiol 51, 973-985.
27. Smith, R. S. & Iglewski, B. H. (2003a). Pseudomonas aeruginosa quorum-sensing systems and virulence. Curr Opin Microbiol 6, 56-60.
28. Smith, R. S. & Iglewski, B. H. (2003b). Pseudomonas aeruginosa quorum sensing as a potential antimicrobial target. J Clin Invest 112, 1460-1465.
29. Vasil, M. L. (2003). DNA microarrays in analysis of quorum sensing: strengths and limitations. J Bacteriol 185, 2061-2065.
30. Wagner, V. E., Bushnell, D., Passador, L., Brooks, A. I. & Iglewski, B. H. (2003). Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment. J Bacteriol 185, 2080-2095.
31. Whiteley, M. & Greenberg, E. P. (2001). Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes. J Bacteriol 183, 5529-5534.
32. Whiteley, M., Lee, K. M. & Greenberg, E. P. (1999). Identification of genes controlled by quorum sensing in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A 96, 13904-13909.
33. Withers, H., Swift, S. & Williams, P. (2001). Quorum sensing as an integral component of gene regulatory networks in Gram-negative bacteria. Curr Opin Microbiol 4, 186-193.