GeneChip® expression analysis of the iron starvation response in Pseudomonas aeruginosa: Identification of novel pyoverdine biosynthesis genes

Molecular Microbiology

Volumn 45, Issue 5, 2002, Pages 1277-1287

  Ochsner, Urs A ^a   Wilderman, Paula J ^a   Vasil, Adriana I ^a   Vasil, Michael L ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PROTEINASE; BACTERIAL PROTEIN; FERREDOXIN; FERROUS ION; FUMARATE HYDRATASE; HEME; IRON; OXIDOREDUCTASE; PROTEIN TONB; PROTEINASE; PSEUDOMONAS EXOTOXIN; PYOVERDINE; SIDEROPHORE; SIGMA FACTOR; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; OLIGOPEPTIDE; PIGMENT; PVDS PROTEIN, PSEUDOMONAS AERUGINOSA;

ARTICLE; BACTERIAL CELL; BIOSYNTHESIS; CORRELATION ANALYSIS; DATA ANALYSIS; DNA MICROARRAY; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE FUSION; GENE IDENTIFICATION; GENETIC CODE; IRON DEFICIENCY; IRON TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PSEUDOMONAS AERUGINOSA; TRANSCRIPTION REGULATION; BACTERIAL GENE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MULTIGENE FAMILY;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

BACTERIAL PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; IRON; MULTIGENE FAMILY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OLIGOPEPTIDES; PIGMENTS, BIOLOGICAL; PSEUDOMONAS AERUGINOSA; SIGMA FACTOR;

EID: 0035982906     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2002.03084.x     Document Type: Article

References (49)

1. Global gene expression profiling in Escherichia coli K12. The effects of integration host factor
2. Ferric uptake regulator mutants of Pseudomonas aeruginosa with distinct alterations in the iron-dependent repression of exotoxin A and siderophores in aerobic and microaerobic environments
3. Global analysis of a bacterial cell cycle: Tracking down necessary functions and their regulators
4. Using DNA microarrays to study host-microbe interactions
5. Cloning and characterization of pvdS, a gene required for pyoverdine synthesis in Pseudomonas aeruginosa: PvdS is probably an alternative sigma factor
6. PfeR, an enterobactin-responsive activator of ferric enterobactin receptor gene expression in Pseudomonas aeruginosa
7. DNA microarrays in drug discovery and development
8. DNA microarray-based identification of genes controlled by autoinducer 2-stimulated quorum sensing in Escherichia coli
9. Antibiotic resistance in Pseudomonas aeruginosa: Mechanisms and impact on treatment
10. An operon containing fumC and sodA encoding fumarase C and manganese superoxide dismutase is controlled by the ferric uptake regulator in Pseudomonas aeruginosa: Fur mutants produce elevated alginate levels
11. Synthesis and activities of pyoverdin-quinolone adducts: A prospective approach to a specific therapy against Pseudomonas aeruginosa
12. A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally -located DNA sequences: Application for isolation of unmarked Pseudomonas aeruginosa mutants
13. Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth
14. Interaction of Pseudomonas aeruginosa with epithelial cells: Identification of differentially regulated genes by expression microarray analysis of human cDNAs
15. DNA microarray technology and antimicrobial drug discovery
16. The synthesis and antibacterial activity of two pyoverdin-ampicillin conjugates, entering Pseudomonas aeruginosa via the pyoverdin-mediated iron uptake pathway
17. Siderophore-mediated signaling regulates virulence factor production in Pseudomonas aeruginosa
18. Genomics of the 35-kb pvd locus and analysis of novel pvdIJK genes implicated in pyoverdine biosynthesis in Pseudomonas aeruginosa
19. Exotoxins of Pseudomonas aeruginosa. I. Factors that influence the production of exotoxin A
20. Effect of iron on accumulation of exotoxin A-specific mRNA in Pseudomonas aeruginosa
21. Exogenous siderophore-mediated iron uptake in Pseudomonas aeruginosa: Possible involvement of porin OprF in iron translocation
22. Pyoverdines: Pigments, siderophores and potential taxonomic markers of fluorescent Pseudomonas species
23. Pyoverdin is essential for virulence of Pseudomonas aeruginosa
24. Autoinducer-mediated regulation of rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa
25. Gene repression by the ferric uptake regulator in Pseudomonas aeruginosa: Cycle selection of iron-regulated genes
26. Role of the ferric uptake regulator of Pseudomonas aeruginosa in the regulation of siderophores and exotoxin A expression: Purification and activity on iron-regulated promoters
27. Exotoxin A production in Pseudomonas aeruginosa requires the iron- regulated pvdS gene encoding an alternative sigma factor
28. Pseudomonas aeruginosa fur overlaps with a gene encoding a novel outer membrane lipoprotein, OmlA
29. Genetics and regulation of two distinct haem-uptake systems, phu and has, in Pseudomonas aeruginosa
30. Role of the Pseudomonas aeruginosa oxyR-recG operon in oxidative stress defense and DNA repair: OxyR-dependent regulation of katB-ankB, ahpB, and ahpC-ahpF
31. DNA microarray analysis of Bacillus subtilis DegU, ComA and PhoP regulons: An approach to comprehensive analysis of B. subtilis two- component regulatory systems
32. Pasteurella multocida gene expression in response to iron limitation
33. Iron metabolism in pathogenic bacteria
34. Identification of a DNA sequence motif required for expression of iron-regulated genes in pseudomonads
35. Microarray-based identification of a novel Streptococcus pneumoniae regulon controlled by an autoinduced peptide
36. A whole-genome microarray reveals genetic diversity among Helicobacter pylori strains
37. Whole genome DNA microarray expression analysis of biofilm development by Vibrio cholerae O1, E1 Tor
38. Improved broad-host-range lac-based plasmid vectors for the isolation and characterization of protein fusions in Pseudomonas aeruginosa
39. An improved system for gene replacement and xylE fusion analysis in Pseudomonas aeruginosa
40. Global differential gene expression in response to growth temperature alteration in group A Streptococcus
41. Complete genome sequence of Pseudomonas aeruginosa PA01, an opportunistic pathogen
42. Impact of siderophore production on Pseudomonas aeruginosa infections in immunosuppressed mice
43. The response of Pseudomonas aeruginosa to iron: Genetics, biochemistry and virulence
44. The fur-regulated gene encoding the alternative sigma factor PvdS is required for iron-dependent expression of the LysR-type regulator ptxR in Pseudomonas aeruginosa
45. Characterization of an endoprotease (PrpL) encoded by a PvdS-regulated gene in Pseudomonas aeruginosa
46. Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization
47. Analysis of promoters recognized by PvdS, an extracyto-plasmic-function sigma factor protein from Pseudomonas aeruginosa
48. The oxygen- and iron-dependent sigma factor pvdS of Pseudomonas aeruginosa is an important virulence factor in experimental infective endocarditis