New atropisomeric biaryl derivatives of 4-aminopyridine - Identification of an improved nucleophilic catalyst for asymmetric acylation of sec-alcohols

Tetrahedron

Volumn 60, Issue 20, 2004, Pages 4513-4525

  Spivey, Alan C ^a,c   Leese, David P ^a   Zhu, Fujiang ^a   Davey, Stephen G ^a   Jarvest, Richard L ^b  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Acylation; Asymmetric catalysis; Atropisomerism; Esterification; Nucleophilic catalysis; sec Alcohols

Indexed keywords

1 (1 NAPHTHYL)ETHANOL; 1 (2 TOLYL)ETHANOL; 1 (2,6 DIMETHYLPHENYL)ETHANOL; 2,2 DIMETHYL 1 PHENYLPROPAN 1 OL; 3 CHLORO 1 PHENYLPROPAN 1 OL; 4 AMINOPYRIDINE DERIVATIVE; ALCOHOL DERIVATIVE; BUTYLAMINE; FLUOXETINE; INDAN 1 OL; SEROTONIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CATALYSIS; CATALYST; CHIRALITY; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KINETICS; PRIORITY JOURNAL; STEREOCHEMISTRY; SYNTHESIS;

EID: 1942468801     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2004.01.098     Document Type: Article

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