메뉴 건너뛰기




Volumn 39, Issue 3, 2003, Pages 183-193

Functionally-distinct proton-binding in HERG suggests the presence of two binding sites

Author keywords

Activation; Deactivation; Gating; Heart; Human ether a go go related gene; I Kr, delayed rectifier; Ischemia; K+ ion channel; pH

Indexed keywords

CATION TRANSPORT PROTEIN; KCNH6 PROTEIN, HUMAN; POTASSIUM CHANNEL; POTASSIUM CHANNEL HERG; PROTON; VOLTAGE GATED POTASSIUM CHANNEL;

EID: 1942467003     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1385/CBB:39:3:183     Document Type: Article
Times cited : (21)

References (33)
  • 1
    • 0029002969 scopus 로고
    • A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel
    • Sanguinetti, M. C., Jiang, C., Curran, M. E., and Keating, M. T. (1995) A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel. Cell 81, 299-307.
    • (1995) Cell , vol.81 , pp. 299-307
    • Sanguinetti, M.C.1    Jiang, C.2    Curran, M.E.3    Keating, M.T.4
  • 2
    • 0029007356 scopus 로고
    • HERG, a human inward rectifier in the voltage-gated potassium channel family
    • Trudeau, M. C., Warmke, J. W., Ganetzky, B., and Robertson, G. A. (1995) HERG, a human inward rectifier in the voltage-gated potassium channel family. Science 269, 92-95.
    • (1995) Science , vol.269 , pp. 92-95
    • Trudeau, M.C.1    Warmke, J.W.2    Ganetzky, B.3    Robertson, G.A.4
  • 3
    • 0028292927 scopus 로고
    • A family of potassium channel genes related to eag in Drosophila and mammals
    • Warmke, J. W. and Ganetzky, B. (1994) A family of potassium channel genes related to eag in Drosophila and mammals. Proc. Nat. Acad. Sci. USA 91, 3438-3442.
    • (1994) Proc. Nat. Acad. Sci. USA , vol.91 , pp. 3438-3442
    • Warmke, J.W.1    Ganetzky, B.2
  • 4
    • 0024325322 scopus 로고
    • Electrophysiological mechanisms of ventricular arrhythmias resulting from myocardial ischemia and infarction
    • Janse, M. J. and Wit, A. L. (1989) Electrophysiological mechanisms of ventricular arrhythmias resulting from myocardial ischemia and infarction. Physiol. Rev. 69, 1049-1169.
    • (1989) Physiol. Rev. , vol.69 , pp. 1049-1169
    • Janse, M.J.1    Wit, A.L.2
  • 5
    • 0026650314 scopus 로고
    • Changes in extracellular and intracellular pH in ischemic rabbit papillary muscle. Circulation Research
    • Yan, G. X. and Kleber, A. G. (1992) Changes in extracellular and intracellular pH in ischemic rabbit papillary muscle. Circulation Research Circ. Res. 71, 460-470.
    • (1992) Circ. Res. , vol.71 , pp. 460-470
    • Yan, G.X.1    Kleber, A.G.2
  • 6
    • 0032778262 scopus 로고    scopus 로고
    • Cardiac ionic currents and acute ischemia: From channels to arrhythmias
    • Carmeliet, E. (1999) Cardiac ionic currents and acute ischemia: from channels to arrhythmias. Physiol. Rev. 79, 917-1017.
    • (1999) Physiol. Rev. , vol.79 , pp. 917-1017
    • Carmeliet, E.1
  • 7
    • 0032780134 scopus 로고    scopus 로고
    • Modulation of HERG potassium channel properties by external pH
    • Beruhe, J., Chahine, M., and Daleau, P. (1999) Modulation of HERG potassium channel properties by external pH. Pflug. Arch. - Eur. J. Physiol. 438, 419-422.
    • (1999) Pflug. Arch. - Eur. J. Physiol. , vol.438 , pp. 419-422
    • Beruhe, J.1    Chahine, M.2    Daleau, P.3
  • 9
    • 0033979153 scopus 로고    scopus 로고
    • Effects of external acidosis on HERG current expressed in Xenopus oocytes
    • Terai, T., Furukawa, T., Katayama, Y., and Hiraoka, M. (2000) Effects of external acidosis on HERG current expressed in Xenopus oocytes. J. Mol. Cell. Cardiol. 32, 11-21.
    • (2000) J. Mol. Cell. Cardiol. , vol.32 , pp. 11-21
    • Terai, T.1    Furukawa, T.2    Katayama, Y.3    Hiraoka, M.4
  • 10
    • 0032731482 scopus 로고    scopus 로고
    • Mechanism for the effects of extracellular acidification on HERG-channel function
    • Jiang, M., Dun, W., and Tseng, G. N. (1999) Mechanism for the effects of extracellular acidification on HERG-channel function. Am. J. Physiol. 277, H1283-H1292.
    • (1999) Am. J. Physiol. , vol.277
    • Jiang, M.1    Dun, W.2    Tseng, G.N.3
  • 12
    • 0030025308 scopus 로고    scopus 로고
    • The inward rectification mechanism of the HERG cardiac potassium channel
    • Smith, P. L., Baukrowitz, T., and Yellen, G. (1996) The inward rectification mechanism of the HERG cardiac potassium channel. Nature 379, 833-836.
    • (1996) Nature , vol.379 , pp. 833-836
    • Smith, P.L.1    Baukrowitz, T.2    Yellen, G.3
  • 13
    • 0030199529 scopus 로고    scopus 로고
    • Time, voltage and ionic concentration dependence of rectification of h-erg expressed in Xenopus oocytes
    • Wang, S., Morales, M. J., Liu, S., Strauss, H. C., and Rasmusson, R. L. (1996) Time, voltage and ionic concentration dependence of rectification of h-erg expressed in Xenopus oocytes. FEBS Letters 389, 167-173.
    • (1996) FEBS Letters , vol.389 , pp. 167-173
    • Wang, S.1    Morales, M.J.2    Liu, S.3    Strauss, H.C.4    Rasmusson, R.L.5
  • 15
    • 0030049457 scopus 로고    scopus 로고
    • Activation and inactivation kinetics of an E-4031-sensitive current from single ferret atrial myocytes
    • Liu, S., Rasmusson, R. L., Campbell, D. L., Wang, S., and Strauss, H. C. (1996) Activation and inactivation kinetics of an E-4031-sensitive current from single ferret atrial myocytes. Biophys. J. 70, 2704-2715.
    • (1996) Biophys. J. , vol.70 , pp. 2704-2715
    • Liu, S.1    Rasmusson, R.L.2    Campbell, D.L.3    Wang, S.4    Strauss, H.C.5
  • 16
    • 0023162302 scopus 로고
    • Conductance and kinetics of delayed rectifier potassium channels in nodal cells of the rabbit heart
    • Shibasaki, T. (1987) Conductance and kinetics of delayed rectifier potassium channels in nodal cells of the rabbit heart. J. Physiol. 387, 227-250.
    • (1987) J. Physiol. , vol.387 , pp. 227-250
    • Shibasaki, T.1
  • 17
    • 0030056967 scopus 로고    scopus 로고
    • Two components of delayed rectifier current in canine atrium and ventricle. Does IKs play a role in the reverse rate dependence of class III agents?
    • Gintant, G. A. (1996) Two components of delayed rectifier current in canine atrium and ventricle. Does IKs play a role in the reverse rate dependence of class III agents? Circ. Res. 78, 26-37.
    • (1996) Circ. Res. , vol.78 , pp. 26-37
    • Gintant, G.A.1
  • 18
    • 0030819954 scopus 로고    scopus 로고
    • A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes
    • Wang, S., Liu, S., Morales, M. J., Strauss, H. C., and Rasmusson, R. L. (1997) A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes. J. Physiol. 502, 45-60.
    • (1997) J. Physiol. , vol.502 , pp. 45-60
    • Wang, S.1    Liu, S.2    Morales, M.J.3    Strauss, H.C.4    Rasmusson, R.L.5
  • 19
    • 0029825403 scopus 로고    scopus 로고
    • Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide
    • Kiehn, J., Lacerda, A. E., Wible, B., and Brown, A. M. (1996) Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide. Circulation 94, 2572-2579.
    • (1996) Circulation , vol.94 , pp. 2572-2579
    • Kiehn, J.1    Lacerda, A.E.2    Wible, B.3    Brown, A.M.4
  • 21
    • 0015879604 scopus 로고
    • Ionic blockage of sodium channels in nerve
    • Woodhull, A. M. (1973) Ionic blockage of sodium channels in nerve. J. Gen. Physiol. 61, 687-708.
    • (1973) J. Gen. Physiol. , vol.61 , pp. 687-708
    • Woodhull, A.M.1
  • 22
    • 0034468569 scopus 로고    scopus 로고
    • Regulation of the cardiac repolarizing HERG potassium channel by protein kinase A
    • Kiehn, J. (2000) Regulation of the cardiac repolarizing HERG potassium channel by protein kinase A. Trends in Cardiovascular Medicine 10, 205-209.
    • (2000) Trends in Cardiovascular Medicine , vol.10 , pp. 205-209
    • Kiehn, J.1
  • 25
    • 0034027205 scopus 로고    scopus 로고
    • The effect of external pH on the delayed rectifying K+ current in cardiac ventricular myocytes
    • Vereecke, J. and Carmeliet, E. (2000) The effect of external pH on the delayed rectifying K+ current in cardiac ventricular myocytes. Plug. Arch. - Eur. J. Physiol. 439, 739-751.
    • (2000) Plug. Arch. - Eur. J. Physiol. , vol.439 , pp. 739-751
    • Vereecke, J.1    Carmeliet, E.2
  • 27
    • 24644480888 scopus 로고    scopus 로고
    • Crystal structure of the potassium channel KirBacl.1 in the closed state
    • Kuo, A., Gulbis, J. M., Antcliff, J. F., Rahman, T., Lowe, E. D., Zimmer, J., et al. (2003) Crystal structure of the potassium channel KirBacl.1 in the closed state. Science 439, 739-751.
    • (2003) Science , vol.439 , pp. 739-751
    • Kuo, A.1    Gulbis, J.M.2    Antcliff, J.F.3    Rahman, T.4    Lowe, E.D.5    Zimmer, J.6
  • 29
    • 0032502286 scopus 로고    scopus 로고
    • pH-dependent gating in the Srreptomyces lividans K+ channel
    • Cuello, L. G., Romero, J. G., Cortes, D. M., and Perozo, E. (1998) pH-dependent gating in the Srreptomyces lividans K+ channel. Biochemistry 37, 3229-3236.
    • (1998) Biochemistry , vol.37 , pp. 3229-3236
    • Cuello, L.G.1    Romero, J.G.2    Cortes, D.M.3    Perozo, E.4
  • 30
    • 0032417420 scopus 로고    scopus 로고
    • The moving parts of voltage-gated ion channels
    • Yellen, G. (1998) The moving parts of voltage-gated ion channels. Quarterly Rev. Biophys. 31, 239-295.
    • (1998) Quarterly Rev. Biophys. , vol.31 , pp. 239-295
    • Yellen, G.1
  • 31
    • 0032478818 scopus 로고    scopus 로고
    • The structure of the potassium channel: Molecular basis of K+ conduction and selectivity
    • Doyle, D. A., Morais, C. J., Pfuetzner, R. A., Kuo, A., Gulbis, J. M., Cohen, S. L., et al. (1998) The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science 280, 69-77.
    • (1998) Science , vol.280 , pp. 69-77
    • Doyle, D.A.1    Morais, C.J.2    Pfuetzner, R.A.3    Kuo, A.4    Gulbis, J.M.5    Cohen, S.L.6
  • 33
    • 12244299383 scopus 로고    scopus 로고
    • Models of cardiac ion channels
    • (Cabo, C. and Rosenbaum, D. S. eds.) Marcel Dekker, Inc., New York, NY
    • Bett, G. C. L. and Rasmusson, R. L. Models of cardiac ion channels, in: Quantitative Cardiac Electrophysiology (Cabo, C. and Rosenbaum, D. S. eds.) Marcel Dekker, Inc., New York, NY, 2002.
    • (2002) Quantitative Cardiac Electrophysiology
    • Bett, G.C.L.1    Rasmusson, R.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.