-
2
-
-
0035895505
-
The sequence of the human genome
-
Venter JC, Adams MD, Meyers EW, Li PW, Mural RJ, et al.: The sequence of the human genome. Science 2001;291: 1304–1351.
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Meyers, E.W.3
Li, P.W.4
Mural, R.J.5
-
3
-
-
0033635776
-
Potassium channels: molecular defects, diseases, and therapeutic opportunities
-
Shieh CC, Coghlan M, Sullivan JP, Gopalakrishnan M: Potassium channels: molecular defects, diseases, and therapeutic opportunities. Pharmacol Rev 2000;52:557–594.
-
(2000)
Pharmacol Rev
, vol.52
, pp. 557-594
-
-
Shieh, C.C.1
Coghlan, M.2
Sullivan, J.P.3
Gopalakrishnan, M.4
-
4
-
-
0036452735
-
An industrial perspective on utilizing functional ion channel assays for high throughput screening
-
Worley JF 3rd, Main MJ: An industrial perspective on utilizing functional ion channel assays for high throughput screening. Receptors Channels 2002;8:269–282.
-
(2002)
Receptors Channels
, vol.8
, pp. 269-282
-
-
Worley, J.F.1
Main, M.J.2
-
5
-
-
0034753261
-
Validation of FLIPR membrane potential dye for high throughput screening of potassium channel modulators
-
Whiteaker KL, Gopalakrishnan SM, Groebe D, Shieh CC, Warrior U, Burns DJ, Coghlan MJ, Scott VE, Gopalakrishnan M: Validation of FLIPR membrane potential dye for high throughput screening of potassium channel modulators. J Biomol Screen 2001;6:305–312.
-
(2001)
J Biomol Screen
, vol.6
, pp. 305-312
-
-
Whiteaker, K.L.1
Gopalakrishnan, S.M.2
Groebe, D.3
Shieh, C.C.4
Warrior, U.5
Burns, D.J.6
Coghlan, M.J.7
Scott, V.E.8
Gopalakrishnan, M.9
-
6
-
-
0344500746
-
Cell-based assays and instrumentation for screening ion-channel targets
-
Gonzalez JE, Oades K, Leychkis Y, Harootunian A, Negulescu PA: Cell-based assays and instrumentation for screening ion-channel targets. Drug Discov Today 1999;4: 431-139.
-
(1999)
Drug Discov Today
, vol.4
-
-
Gonzalez, J.E.1
Oades, K.2
Leychkis, Y.3
Harootunian, A.4
Negulescu, P.A.5
-
7
-
-
0035892592
-
Ion-channel assay technologies: quo vadis
-
Xu J, Wang X, Ensign B, Li M, Wu L, Guia A: Ion-channel assay technologies: quo vadis? Drug Discov Today 2001;6:1278–1287.
-
(2001)
Drug Discov Today
, vol.6
, pp. 1278-1287
-
-
Xu, J.1
Wang, X.2
Ensign, B.3
Li, M.4
Wu, L.5
Guia, A.6
-
8
-
-
0033179793
-
Functional analysis of native and recombinant ion channels using a high-capacity nonradioactive rubidium efflux assay
-
Terstappen GC: Functional analysis of native and recombinant ion channels using a high-capacity nonradioactive rubidium efflux assay. Anal Biochem 1999;272:149–155.
-
(1999)
Anal Biochem
, vol.272
, pp. 149-155
-
-
Terstappen, G.C.1
-
9
-
-
0034063414
-
+ channel Kir6.2 combination expressed in HEK-293 cells
-
+ channel Kir6.2 combination expressed in HEK-293 cells. Br J Pharmacol 2000;129:1323–1332.
-
(2000)
Br J Pharmacol
, vol.129
, pp. 1323-1332
-
-
Gopalakrishnan, M.1
Molinari, E.J.2
Shieh, C.C.3
Monteggia, L.M.4
Roch, J.M.5
Whiteaker, K.L.6
Scott, V.E.7
Sullivan, J.P.8
Brioni, J.D.9
-
11
-
-
0019441262
-
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
-
Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ: Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 1981;391:85–100.
-
(1981)
Pflugers Arch
, vol.391
, pp. 85-100
-
-
Hamill, O.P.1
Marty, A.2
Neher, E.3
Sakmann, B.4
Sigworth, F.J.5
-
12
-
-
12244299864
-
Upscaling and automation of electrophysiology: toward high throughput screening in ion channel drug discovery
-
Asmild M, Oswald N, Krzywkowski KM, Friis S, Jacobsen RB, Reuter D, Taboryski R, Kutchinsky J, Vestergaard RK, Schroder RL, Sorensen CB, Bech M, Korsgaard MP, Willumsen NJ: Upscaling and automation of electrophysiology: toward high throughput screening in ion channel drug discovery. Receptors Channels 2003;9:49–58.
-
(2003)
Receptors Channels
, vol.9
, pp. 49-58
-
-
Asmild, M.1
Oswald, N.2
Krzywkowski, K.M.3
Friis, S.4
Jacobsen, R.B.5
Reuter, D.6
Taboryski, R.7
Kutchinsky, J.8
Vestergaard, R.K.9
Schroder, R.L.10
Sorensen, C.B.11
Bech, M.12
Korsgaard, M.P.13
Willumsen, N.J.14
-
13
-
-
0037178198
-
Micromolded PDMS planar electrode allows patch clamp electrical recordings from cells
-
Klemic KG, Klemic JF, Reed MA, Sigworth FJ: Micromolded PDMS planar electrode allows patch clamp electrical recordings from cells. Biosens Bioelectron 2002;17:597–604.
-
(2002)
Biosens Bioelectron
, vol.17
, pp. 597-604
-
-
Klemic, K.G.1
Klemic, J.F.2
Reed, M.A.3
Sigworth, F.J.4
-
14
-
-
0036106307
-
Whole cell patch clamp recording performed on a planar glass chip
-
Fertig N, Blick RH, Behrends JC: Whole cell patch clamp recording performed on a planar glass chip. Biophys J 2002;82:3056–3062.
-
(2002)
Biophys J
, vol.82
, pp. 3056-3062
-
-
Fertig, N.1
Blick, R.H.2
Behrends, J.C.3
-
15
-
-
0042895988
-
High throughput ion-channel pharmacology: planar-array-based voltage clamp
-
Kiss L, Bennett PB, Uebele VN, Koblan KS, Kane SA, Neagle B, Schroeder K: High throughput ion-channel pharmacology: planar-array-based voltage clamp. Assay Drug Dev Technol 2003;1:127–135.
-
(2003)
Assay Drug Dev Technol
, vol.1
, pp. 127-135
-
-
Kiss, L.1
Bennett, P.B.2
Uebele, V.N.3
Koblan, K.S.4
Kane, S.A.5
Neagle, B.6
Schroeder, K.7
-
16
-
-
0041888478
-
Ionworks™ HT: a new high-throughput electrophysiology measurement platform
-
Schroeder K, Neagle B, Trezise DJ, Worley J: Ionworks™ HT: a new high-throughput electrophysiology measurement platform. J Biomol Screen 2003;8:50–64.
-
(2003)
J Biomol Screen
, vol.8
, pp. 50-64
-
-
Schroeder, K.1
Neagle, B.2
Trezise, D.J.3
Worley, J.4
-
17
-
-
0021039274
-
Voltage-operated channels induced by foreign messenger RNA in Xenopus oocytes
-
Gundersen CB, Miledi R, Parker I: Voltage-operated channels induced by foreign messenger RNA in Xenopus oocytes. Proc R Soc Lond [Biol] 1983;220:131–140.
-
(1983)
Proc R Soc Lond [Biol]
, vol.220
, pp. 131-140
-
-
Gundersen, C.B.1
Miledi, R.2
Parker, I.3
-
18
-
-
0002919262
-
Electrophysiological recordings from Xenopus oocytes
-
2nd ed. Sakmann B, Neher E (eds.), Plenum Press, New York
-
Stuhmer W, Parekh AB: Electrophysiological recordings from Xenopus oocytes. In: Single-Channel Recording, 2nd ed. Sakmann B, Neher E (eds.), pp. 341–356. Plenum Press, New York, 1995.
-
(1995)
Single-Channel Recording
, pp. 341-356
-
-
Stuhmer, W.1
Parekh, A.B.2
-
19
-
-
0032313557
-
High-level expression and detection of ion channels in Xenopus oocytes
-
Shih TM, Smith RD, Toro L, Goldin AL: High-level expression and detection of ion channels in Xenopus oocytes. Methods Enzymol 1998;293:529–556.
-
(1998)
Methods Enzymol
, vol.293
, pp. 529-556
-
-
Shih, T.M.1
Smith, R.D.2
Toro, L.3
Goldin, A.L.4
-
20
-
-
0037232056
-
The roboocyte: automated cDNA/mRNA injection and subsequent TEVC recording on Xenopus oocytes in 96-well microtiter plates
-
Schnizler K, Kuster M, Methfessel C, Fejtl M: The roboocyte: automated cDNA/mRNA injection and subsequent TEVC recording on Xenopus oocytes in 96-well microtiter plates. Receptors Channels 2003;9:41–48.
-
(2003)
Receptors Channels
, vol.9
, pp. 41-48
-
-
Schnizler, K.1
Kuster, M.2
Methfessel, C.3
Fejtl, M.4
-
21
-
-
12244269066
-
High throughput electrophysiology using a fully automated, multiplexed recording system
-
Trumbull JD, Bertrand D, Maslana ES, McKenna DG, Nemcek TA, Niforatos W, Pan JF, Parihar AS, Shieh C-C, Wilkins JA, Briggs CA: High throughput electrophysiology using a fully automated, multiplexed recording system. Receptors Channels 2003;9:19–28.
-
(2003)
Receptors Channels
, vol.9
, pp. 19-28
-
-
Trumbull, J.D.1
Bertrand, D.2
Maslana, E.S.3
McKenna, D.G.4
Nemcek, T.A.5
Niforatos, W.6
Pan, J.F.7
Parihar, A.S.8
Shieh, C.-C.9
Wilkins, J.A.10
Briggs, C.A.11
-
22
-
-
0033003760
-
A simple statistical parameter for use in evaluation and validation of high throughput screening assays
-
Zhang JH, Chung TD, Oldenburg KR: A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 1999;4:67–73.
-
(1999)
J Biomol Screen
, vol.4
, pp. 67-73
-
-
Zhang, J.H.1
Chung, T.D.2
Oldenburg, K.R.3
|