Pharmacology of human sulphonylurea receptor SUR1 and inward rectifier K+ channel Kir6.2 combination expressed in HEK-293 cells

British Journal of Pharmacology

Volumn 129, Issue 7, 2000, Pages 1323-1332

  Gopalakrishnan, Murali ^a,b   Molinari, Eduardo J ^a   Shieh, Char Chang ^a   Monteggia, Lisa M ^a,d   Roch, Jean Marc ^c   Whiteaker, Kristi L ^a   Scott, Victoria E S ^a   Sullivan, James P ^a   Brioni, Jorge D ^a  

^a ABBOTT LABORATORIES   (United States)

^b Pharmaceutical Products Division   (United States)

^c Myriad Genetic Laboratories   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ATP sensitive potassium channel; Glyburide (glibenclamide); HEK293 cell line; Inwardly rectifying potassium channel; Potassium channel opener; Sulphonylurea receptor

Indexed keywords

DEOXYGLUCOSE; DIAZOXIDE; GLIBENCLAMIDE; HYPERGLYCEMIC AGENT; LEMAKALIM; MACROLIDE; OLIGOMYCIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; POTASSIUM ION; RUBIDIUM 86; SULFONYLUREA DERIVATIVE;

ARTICLE; CELL MEMBRANE POTENTIAL; DRUG BINDING; HUMAN; HUMAN CELL; KIDNEY CELL; LIGAND BINDING; PATCH CLAMP; PRIORITY JOURNAL;

EID: 0034063414     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703181     Document Type: Article

References (52)

1. Aguilar-Bryan, L. & BRYAN, J. (1999). Molecular biology of adenosine triphosphate-sensitive potassium channels. Endocr. Rev., 20, 101-135.
2. + channel Kir6.1 expressed in human embryonic kidney cells. J. Physiol., 494, 709-714.
3. + channels. Science, 247, 852-854.
4. Ashcroft, F.M. & Rorsman, P. (1991). Electrophysiology of the pancreatic β-cell. Prog. Biophys. Mol. Biol., 54: 87-143.
5. Ashcroft, S.J.H. & Ashcroft, F.M. (1992). The sulfonylurea receptor. Biochim. Biophys. Acta, 1175, 45-59.
6. + channels. Trends Neurosci., 21, 288-294.
7. ATP channels. Annu. Rev. Physiol., 60, 667-687.
8. Boyd, A.E., Aguilar-Bryan, L. & Nelson, D.A. (1990). Molecular mechanisms of action of glyburide on the beta cell. Am. J. Med., 89, (Suppl. 2A): 3S-9S.
9. Bryan, J. & Aguilar-Bryan, L. (1997). The ABCs of ATP-sensitive potassium channels more pieces of the puzzle. Curr. Opin. Cell Biol., 9, 553-559.
10. 2+. J. Mem. Biol., 103, 171-180.
11. ATP channel subunits. Neuron, 18, 827-838.
12. + channels by fluorescein derivatives. J. Biol. Chem., 267, 4557-4563.
13. Dörschner, H., Brekardin, E., Uhde, I., Schwanstecher, C. & Schwanstecher, M. (1999). Stoichiometry of sulfonylurea-induced ATP-sensitive potassium channel closure. Mol. Pharmacol., 55, 1060-1066.
14. Eliasson, L., Renstrom, E., Ammala, C., Berggren, P.O., Bertorello, A.M., Bokvist, K., Chibalin, A., Deeney, J.T., Flatt, P.R., Gabel, J., Gromada, J., Larsson, O., Lindstrom, P., Rhodes, C.J., &5 Rorsman, P. (1996). PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic beta cells. Science, 271, 813-815.
15. Garlid, K.D., Paucek, P., Yarov-Yarovoy, B., Murray, H.N.M., Darbenzio, R.B., D'Alonzo, A.J., Lodge, N.J., Smith, M.A. & Grover, G.J. (1997). Cardioprotective effect of diazoxide and its interaction with mitochondrial ATP-sensitive potassium channels. Possible mechanisms of cardioprotection. Circ. Res., 81, 1072-1082.
16. Gopalakrishnan, M & Molinari, E.J. (1998). Expression of cloned receptors in mammalian cell lines. In: Current Protocols in Pharmacology, Unit 6.3, NY: John Wiley pp. 6.3.1-6.3.13.
17. Gopalakrishnan, M., Janis, R.A. & Triggle, D.J. (1993). ATP-sensitive potassium channels: pharmacological properties, regulation and therapeutic potential. Drug Dev. Res., 28, 95-127.
18. 3H]-glyburide, to neuronal and muscle preparations. J. Pharmacol. Exp. Ther., 257, 1162-1171.
19. Gopalakrishnan, M., Molinari, E., Shieh, C.-C., Monteggia, L.M., Roch, J.-M., Scott, V.E.S., Anderson, K.A., Sullivan, J.P. & Brioni, J.D. (1999a). Stable expression of the sulfonylurea receptor SUR1 and the inward rectifier Kir6.2: Pharmacology of ligand binding and function. Biophys. J., A74.
20. ATP) in guinea-pig bladder smooth muscle cells. J. Pharmacol. Exp. Ther., 289, 551-558.
21. + currents expressed in Xenopus oocytes. J. Physiol., 498, 87-98.
22. + channel modulator binding to sulfonylurea receptors SUR2A and SUR2B: Opposite effects of MgADP. Mol. Pharmacol., 55, 832-840.
23. Hodgkin, A.L. & Horowicz, P. (1959). The influence of potassium and chloride ions on the membrane potential of single muscle fibres. J. Physiol., 148, 127-160.
24. Holemans, S., Feron, O., Octave, J. & Maloteaux, J. (1995). Interaction of fluorescein derivatives with glibenclamide binding sites in rat brain. Neurosci. Lett., 183, 183-186.
25. KATP: An inward rectifier subunit plus the sulfonylurea receptor. Science, 270, 1166-1170.
26. + channels. Neuron, 16, 1011-1017.
27. + channel. J. Biol. Chem., 271, 24321-24324.
28. + channels in the cardiovascular system. J. Cardiovasc. Electrophysiol., 8, 1431-1446.
29. + channels linked to the green fluorescent protein in human embryonic kidney cells (HEK 293). J. Physiol., 510, 333-345.
30. ATP channel formation by the sulfonylurea receptors SUR1 with Kir6.2 subunits in rat dorsal vagal neurons in situ. J. Physiol. (Lond.), 509, 339-346.
31. Karschin, C., Ecke, C., Ashcroft, F.M. & Karschin, A. (1997). Overlapping distribution of KATP channel-forming Kir6.2 subunit and the sulfonylurea receptor SUR1 in rodent brain. FEBS Lett., 401, 59-64.
32. nd International Conference on ATP-sensitive potassium channels and disease, St. Charles, IL, Abstr 226.
33. Liu, Y., Sato, T., O'Rourke, B. & Marban, E. (1998). Mitochondrial ATP-dependent potassium channels. Novel effectors of cardioprotection? Circulation, 97, 2463-2469.
34. Mangel, A.W., Prpic, V., Snow, N.D., Basavappa, S., Hurst, L.J., Sharara, A.I. & Liddle, R.A. (1994). Regulation of cholecystokinin secretion by ATP-sensitive potassium channels. Am. J. Physiol. 267, G595-G600.
35. Meyer, M., Chudziak, F., Schwanstecher, C., Schwanstecher, M. & Panten, U. (1999). Structural requirements of sulfonylureas and analogues for interaction with sulfonylureas receptor subtypes. Br. J. Pharmacol., 128, 27-34.
36. + channels in insect cells using baculovirus. FEBS Lett., 429, 390-394.
37. Miki, T., Inagaki, N., Nagashima, K., Gonoi, T. & Seino, S. (1999). Structure and function of ATP-sensitive potassium channels. In: Potassium Ion Channels: Molecular Structure, Function and Diseases. Kurachi, Y., Jan, L.Y. Lazdunski, M. (eds). San Diego: Academic Press. pp. 373-385.
38. + channels in the TE671 human medulloblastoma cell line. Eur. J. Pharmacol., 370, 179-185.
39. ATP channel from human aorta. Br. J. Pharmacol., 102P.
40. Nichols, C.G., Makhina, E.N., Pearson, W.L., Sha, Q. & Lopatin, A.N. (1996). Inward rectification and implications for cardiac excitability. Circ. Res., 78, 1-7.
41. + channels in cardiac muscle. Nature, 305, 147-148.
42. + channel expressed in a mammalian cell line, HEK293T cells. Pfluger's Arch., 435, 595-603.
43. Quayle, J.M., Nelson, M.T. & Standen, N.B. (1997). ATP-sensitive and inwardly rectifying potassium channels in smooth muscle. Physiol. Rev., 77, 1165-1231.
44. + channel in insulin-secreting cells. J. Biol. Chem., 262, 15840-15844.
45. Schroeder, K.S. & Neagle, B.D. (1996). FLIPR: A new instrument for accurate, high throughput optical screening. J. Biomol. Screen, 1, 75-81.
46. Schwanstecher, M., Sieverding, C., Dorschner, H., Gross, I., Aguilar-Bryan, L., Schwanstecher, C. & Bryan, J. (1998). Potassium channel openers require ATP to bind to and act through sulfonylurea receptors. EMBO J., 17, 5529-5535.
47. ATP channel activity by diazoxide and MgADP. Distinct functions of the two nucleotide binding folds of the sulfonylurea receptor. J. Gen. Physiol., 110, 643-654.
48. Shyng, S.L. & Nichols, C.G. (1998). Membrane phospholipid control of nucleotide sensitivity of KATP channels. Science, 282, 1138-1141.
49. + channels. Nature, 390, 521-525.
50. + channels in the absence of the sulphonylurea receptor. Nature, 387, 179-183.
51. Uhde, I, Toman, A, Gross, I, Schwanstecher, C & Schwanstecher, M. (1999). Identification of the potassium channel opener site on sulfonylurea receptors. J. Biol. Chem., 274, 28079-28082.
52. Xu, T., Jiao, J.H., Pence, R.A. & Baertschi, A.J. (1996). ATP-sensitive potassium channels regulate stimulated ANF secretion in isolated rat heart. Am. J. Physiol., 271, H2339-H2345.