Molecular Modeling of the Binding of 5-Substituted 2′-Deoxyuridine Substrates to Thymidine Kinase of Herpes Simplex Virus Type-1

Nucleosides, Nucleotides and Nucleic Acids

Volumn 23, Issue 3, 2004, Pages 555-565

  Harris, Douglas G ^a   Shao, Jianyin ^a   Morrow, Benjamin D ^a   Zimmerman, S Scott ^a  

^a Brigham Young University   (United States)

Author keywords

Deoxyuridine substrates; Herpes simplex virus type 1; Herpesviridae; IC50 values; Thymidine kinase

Indexed keywords

DEOXYURIDINE; LIGAND; PYRIMIDINE 1,5 ANHYDROHEXITOL; PYRIMIDINE DERIVATIVE; THYMIDINE KINASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHEMICAL BOND; ENERGY; HERPES SIMPLEX VIRUS 1; HERPES VIRUS; IC 50; LIGAND BINDING; MOLECULAR MODEL; RIGIDITY;

DEOXYURIDINE; HERPESVIRUS 1, HUMAN; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PROTEIN BINDING; THYMIDINE KINASE;

HERPESVIRIDAE; HUMAN HERPESVIRUS 1; SIMPLEXVIRUS;

EID: 1942454911     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-120030714     Document Type: Article

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