Computational studies on HIV-1 protease inhibitors: Influence of calculated inhibitor-enzyme binding affinities on the statistical quality of 3D-QSAR CoMFA models

Journal of Medicinal Chemistry

Volumn 43, Issue 23, 2000, Pages 4446-4451

  Jayatilleke, P R N ^a   Nair, A C ^a   Zauhar, R ^b   Welsh, W J ^a  

^a UNIVERSITY OF MISSOURI ST LOUIS   (United States)

^b UNIVERSITY OF THE SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INDINAVIR; PROTEINASE INHIBITOR;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG BINDING; DRUG DESIGN; ENZYME BINDING; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PROTEINASE INHIBITION; STRUCTURE ACTIVITY RELATION; VIRUS REPLICATION;

HIV PROTEASE; HIV PROTEASE INHIBITORS; INDINAVIR; PROTEIN BINDING; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 0034676326     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9905357     Document Type: Article

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