Correlation of Wnt-2 expression and β-catenin intracellular accumulation in Chinese gastric cancers: Relevance with tumour dissemination

Cancer Letters

Volumn 223, Issue 2, 2005, Pages 339-347

  Cheng, Xiao Xin ^a   Wang, Zi Chuang ^a   Chen, Xiao Yan ^a   Sun, Yuan ^a   Kong, Qing You ^a   Liu, Jia ^a   Li, Hong ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

catenin; Gastric cancer; Lymph node metastasis; Tumour progression; Wnt2

Indexed keywords

BETA CATENIN; WNT PROTEIN;

ANALYTIC METHOD; ARTICLE; CANCER STAGING; CELLULAR DISTRIBUTION; CHRONIC GASTRITIS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FROZEN SECTION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE CANCER; INTESTINE METAPLASIA; LYMPH NODE METASTASIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STOMACH CANCER; UPREGULATION; WESTERN BLOTTING;

BETA CATENIN; BLOTTING, WESTERN; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; CHINA; CYTOPLASM; CYTOSKELETAL PROTEINS; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PRECANCEROUS CONDITIONS; PROTO-ONCOGENE PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TRANS-ACTIVATORS; UP-REGULATION; WNT2 PROTEIN;

EID: 19344378616     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2004.11.013     Document Type: Article

References (41)

1. N.Y. Hsu, K.C. Chow, W.J. Chen, C.C. Lin, F.F. Chou, and C.L. Chen Expression of nm23 in the primary tumor and the metastatic regional lymph nodes of patients with gastric cardiac cancer Clin. Cancer Res. 5 1999 1752 1757
2. K. Yasuda, N. Shiraishi, T. Suematsu, K. Yamaguchi, Y. Adachi, and S. Kitano Rate of detection of lymph node metastasis is correlated with the depth of submucosal invasion in early stage gastric carcinoma Cancer 85 1999 2119 2123
3. F.T. Kolligs, G. Bommer, and B. Goke Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis Digestion 66 2002 131 144
4. B. Lustig, and J. Behrens The wnt signaling pathway and its role in tumor development J. Cancer Res. Clin. Oncol. 129 2003 199 221
5. V.J. Wielenga, R. Smits, V. Korinek, L. Smit, M. Kielman, and R. Fodde Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway Am. J. Pathol. 154 1999 515 523
6. A.V. Ougolkov, K. Yamashita, M. Mai, and T. Minamoto Oncogenic beta-catenin and MMP-7 (matrilysin) cosegregate in late-stage clinical colon cancer Gastroenterology 122 2002 60 71
7. M. Tanaka, Y. Kitajima, G. Edakuni, S. Sato, and K. Miyazaki Abnormal expression of E-cadherin and beta-catenin may be a molecular marker of submucosal invasion and lymph node metastasis in early gastric cancer Br. J. Surg. 89 2002 236 244
8. A. Boussioutas, H. Li, J. Liu, P. Waring, S. Lade, and A.J. Holloway Distinctive patterns of gene expression in premalignant gastric mucosa and gastric cancer Cancer Res. 63 2003 2569 2577
9. M. Katoh Differential regulation of WNT2 and WNT2B expression in human cancer Int. J. Mol. Med. 8 2001 657 660
10. M. Katoh Frequent up-regulation of WNT2 in primary gastric cancer and colorectal cancer Int. J. Oncol. 19 2001 1003 1007
11. T. Saitoh, T. Mine, and M. Katoh Frequent up-regulation of WNT5A mRNA in primary gastric cancer Int. J. Mol. Med. 9 2002 515 519
12. H. Li, Y. Sun, Q.Y. Kong, K.L. Zhang, X.W. Wang, and X.Y. Chen Combination of nucleic acid and protein isolation with tissue array construction: using defined histological regions in single frozen tissue blocks for multiple research purposes Int. J. Mol. Med. 12 2003 299 304
13. Q. Wang, H. Li, X.W. Wang, D.C. Wu, X.Y. Chen, and J. Liu Resveratrol promotes differentiation and induces Fas-independent apoptosis of human medulloblastoma cells Neurosci. Lett. 351 2003 83 86
14. M.P. Ebert, G. Fei, S. Kahmann, O. Muller, J. Yu, J.J. Sung, and P. Malfertheiner Increased beta-catenin mRNA levels and mutational alterations of the APC and beta-catenin gene are present in intestinal-type gastric cancer Carcinogenesis 23 2002 87 91
15. P. Laur'en The two histological main types of gastric carcinoma: diffuse and so-called intestinal type carcinoma. An attempt at a histoclinical classification Acta Pathol. Microbiol. Scand. 64 1965 31 49
16. T.C. Dale Signal transduction by the wnt family of ligands Biochem. J. 329 1998 209 223
17. E. Pennisi How a growth control path takes a wrong turn to cancer Science 281 1998 1438 1441
18. W.J. Nelson, and R. Nusse Convergence of Wnt, beta-catenin, and cadherin pathways Science 303 2004 1483 1487
19. W.S. Samowitz, M.D. Powers, L.N. Spirio, F. Nollet, F. van Roy, and M.L. Slattery Beta-catenin mutations ate more frequent in small colorectal adenomas than in larger adenomas and invasive carcinomas Cancer Res. 59 1999 1442 1444
20. A. de la Coste, B. Romagnolo, P. Billuart, C.A. Renard, M.A. Buendia, and O. Soubrane Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas Proc. Natl Acad. Sci. USA 95 1998 8847 8851
21. D.L. Rimm, K. Caca, G. Hu, F.B. Harrison, and E.R. Fearon Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma Am. J. Pathol. 154 1999 325 329
22. H. Grabsch, and S. Takeno Different patterns of beta-catenin expression in gastric carcinomas: relationship with clinicopathological parameters and prognostic outcome Histopathology 39 2001 141 149
23. D.K. Woo, H.S. Kim, H.S. Lee, Y.H. Kang, H.K. Yang, and W.H. Kim Altered expression and mutation of beta-catenin gene in gastric carcinomas and cell lines Int. J. Cancer 95 2001 108 113
24. J.H. Lee, S.C. Abraham, H.S. Kim, J.H. Nam, C. Choi, and M.C. Lee Inverse relationship between APC gene mutation in gastric adenomas and development of adenocarcinoma Am. J. Pathol. 161 2002 611 618
25. B.R. Henderson, and F. Fagotto The ins and outs of APC and beta-catenin nuclear transport Eur. Mol. Biol. Org. Rep. 3 2002 834 839
26. J.R. Miller The Wnts Genome Biol. 3 2002 3001.1 3001.15
27. L.B. Koppert, A.W. van der Velden, M. van de Wetering, M. Abbou, A.M. van den Ouweland, and H.W. Tilanus Frequent loss of the AXIN1 locus but absence of AXIN1 gene mutations in adenocarcinomas of the gastro-oesophageal junction with nuclear beta-catenin expression Br. J. Cancer 90 2004 892 899
28. S. Candidus, P. Bischoff, K.F. Becker, and H. Hofler No evidence for mutations in alpha- and beta-catenin genes in human gastric and breast carcinomas Cancer Res. 56 1996 49 52
29. P. Polakis Wnt signaling and cancer Genes Dev. 14 2000 1837 1851
30. W.M. Clements, J. Wang, A. Sarnaik, O.J. Kim, J. MacDonald, and C. Fenoglio-Preiser Beta-Catenin mutation is a frequent cause of Wnt pathway activation in gastric cancer Cancer Res. 62 2002 3503 3506
31. M. Shimizu, M. Szui, H. Moriwaki, H. Morin, and N. Yoshimi No involvement of beta-catenin gene mutation in gastric carcinomas induced by N-methyl-N-nitrosourea in male F344 rats Cancer Lett. 195 2003 147 152
32. M. Miyaki, T. Iijima, J. Kimura, M. Yasuno, T. Mori, and Y. Hayashi Frequent mutation of beta-catenin and APC genes in primary colorectal tumors from patients with hereditary nonpolyposis colorectal cancer Cancer Res. 59 1999 4506 4509
33. Y. Ishizaki, S. Ikeda, M. Fujimori, Y. Shimizu, T. Kurihara, and T. Itamoto Immunohistochemical analysis and mutational analyses of beta-catenin. Axin family and APC genes in hepatocellular carcinomas Int. J. Oncol. 24 2004 1077 1083
34. J.H. Tong, K.F. To, E.K. Ng, J.Y. Lau, T.L. Lee, and K.W. Lo Somatic beta-catenin mutation in gastric carcinoma-an infrequent event that is not specific for microsatellite instability Cancer Lett. 163 2001 125 130
35. B.J. Song, Y.J. Park, H.S. Kim, C.N. Kim, and S.H. Chang Expression of beta-catenin and E-cadherin in early gastric cancer: correlation with clinicopathologic parameters Korean J. Gastroenterol. 43 2004 82 89
36. M. Katoh Wnt2 and human gastrointestinal cancer Int. J. Mol. Med. 12 2003 811 816
37. H.C. Chen, R.Y. Chu, P.N. Hsu, P.I. Hsu, J.Y. Lu, and K.H. Lai Loss of E-cadherin expression correlates with poor differentiation and invasion into adjacent organs in gastric adenocarcinomas Cancer Lett. 201 2003 97 106
38. H.S. Kim, E.K. Hong, S.Y. Park, W.H. Kim, and H.S. Lee Expression of beta-catenin and E-cadherin in the adenoma-carcinoma sequence of the stomach Anticancer Res. 23 2003 2863 2868
39. M. Mareel, and A. Leroy Clinical, cellular, and molecular aspects of cancer invasion Physiol Rev. 83 2003 337 376
40. P. Blok, M.E. Craanen, W. Dekker, and G.N. Tytgat Loss of E-cadherin expression in early gastric cancer Histopathology 34 1999 410 415
41. Y.E. Joo, J.S. Rew, H.S. Kim, S.H. Choi, C.S. Park, and S.J. Kim Changes in the E-cadherin-catenin complex expression in early and advanced gastric cancers Digestion 64 2001 111 119