Differential effects of amphetamines-induced neurotoxicity on appetitive and aversive Pavlovian conditioning in mice

Neuropsychopharmacology

Volumn 30, Issue 6, 2005, Pages 1128-1137

  Achat Mendes, Cindy ^a   Ali, Syed F ^b   Itzhak, Yossef ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Associative learning; Conditioned place aversion (CPA); Conditioned place preference (CPP); Dopamine; Psychostimulants; Serotonin

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; AMPHETAMINE; DOPAMINE; FENFLURAMINE; LITHIUM CHLORIDE; METHAMPHETAMINE; SEROTONIN;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; APPETITE; ARTICLE; AUTOPSY; AVERSIVE BEHAVIOR; CONDITIONING; CONTROLLED STUDY; CORPUS STRIATUM; FRONTAL CORTEX; HIPPOCAMPUS; LEARNING; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; PLACE PREFERENCE; PRIORITY JOURNAL; REWARD;

AMPHETAMINES; ANIMALS; ANTIMANIC AGENTS; APPETITIVE BEHAVIOR; AVOIDANCE LEARNING; CENTRAL NERVOUS SYSTEM STIMULANTS; CONDITIONING, CLASSICAL; DOPAMINE; FENFLURAMINE; HALLUCINOGENS; LITHIUM CHLORIDE; MALE; METHAMPHETAMINE; MICE; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; NERVE ENDINGS; NEUROTOXICITY SYNDROMES; RECEPTORS, SEROTONIN; REINFORCEMENT (PSYCHOLOGY); REWARD; SEROTONIN;

EID: 19344376658     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300675     Document Type: Article

References (59)

1. Achat-Mendes C, Anderson KL, Itzhak Y (2003). Methylphenidate and MDMA adolescent exposure in mice: long-lasting consequences on cocaine-induced reward and psychomotor stimulation in adulthood. Neuropharmacology 45: 106-115.
2. Bardo MT (1998). Neuropharmacological mechanisms of drug reward: beyond dopamine in the nucleus accumbens. Crit Rev Neurobiol 12: 37-67.
3. Bassareo V, Tanda G, Petromilli P, Giua C, Di Chiara G (1996). Non-psychostimulant drugs of abuse and anxiogenic drugs activate with differential selectivity dopamine transmission in the nucleus accumbens and in the medial prefrontal cortex of the rat. Psychopharmacology (Berl) 124: 293-299.
4. Bhattachary S, Powell JH (2001). Recreational use of 3,4- methylenedioxymethamphetamine (MDMA) or ecstasy: evidence for cognitive impairment. Psychol Med 31: 647-658.
5. Bolla KI, McCann UD, Ricaurte GA (1998). Memory impairment in abstinent MDMA ('Ecstasy') users. Neurology 51: 1532-1537.
6. Brown P, Molliver ME (2000). Dual serotonin (5-HT) projections to the nucleus accumbens core and shell: relation of the 5-HT transporter to amphetamine-induced neurotoxicity. J Neurosci 20: 1952-1963.
7. Chang L, Ernst T, Speck O, Patel H, DeSilva M, Leonido-Yee M et al (2002). Perfusion MRI and computerized cognitive test abnormalities in abstinent methamphetamine users. Psychiatry Res 114: 65-79.
8. Chapman DE, Hanson GR, Kesner RP, Keefe KA (2001). Long-term changes in basal ganglia function after a neurotoxic regimen of methamphetamine. J Pharmacol Exper Ther 296: 520-527.
9. Cunningham CL, Noble D (1992). Methamphetamine-induced conditioned place preference or aversion depending on dose and presence of drug. Ann NY Acad Sci 654: 431-433.
10. Davidson C, Gow AJ, Lee TH, Ellinwood EH (2001). Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment. Brain Res Brain Res Rev 36: 1-22.
11. Di Chiara G (2002). Nucleus accumbens shell and core dopamine: differential role in behavior and addiction. Behav Brain Res 137: 75-114.
12. Fletcher PJ, Korth KM, Chambers JW (1999). Selective destruction of brain serotonin neurons by 5,7-dihydroxytryptamine increases responding for a conditioned reward. Psychopharmacology (Berl) 147: 291-299.
13. Freese T, Miotto K, Reback C (2002). The effects and consequences of selected club drugs. J Subst Abuse Treat 23: 151-156.
14. Friedman SD, Castaneda E, Hodge GK (1998). Long-term monoamine depletion, differential recovery, and subtle behavioral impairment following methamphetamine-induced neurotoxicity. Pharmacol Biochem Behav 61: 35-44.
15. Gallagher M, Graham PW, Holland PC (1990). The amygdala central nucleus and appetitive Pavlovian conditioning: lesions impair one class of conditioned behavior. J Neurosci 10: 1906-1911.
16. Gehrke BJ, Harrod SB, Cass WA, Bardo MT (2003). The effect of neurotoxic doses of methamphetamine on methamphetamine-conditioned place preference in rats. Psychopharmacology (Berl) 166: 249-257.
17. Gibb JW, Johnson M, Stone D, Hanson GR (1990). MDMA: historical perspectives. Ann N Y Acad Sci 600: 601-612.
18. Gibson DR, Leamon MH, Flynn N (2002). Epidemiology and public health consequences of methamphetamine use in California's Central Valley. J Psychoactive Drugs 34: 313-319.
19. Gouzoulis-Mayfrank E, Thimm B, Rezk M, Hensen G, Daumann J (2003). Memory impairment suggests hippocampal dysfunction in abstinent ecstasy users. Prog Neuropsychopharmacol Biol Psychiatry 27: 819-827.
20. Isaac WL, Nonneman AJ, Neisewander J, Landers T, Bardo MT (1989). Prefrontal cortex lesions differentially disrupt cocaine-reinforced conditioned place preference but not conditioned taste aversion. Behav Neurosci 103: 345-355.
21. Itzhak Y, Achat-Mendes C (2004). Methamphetamine and MDMA (Ecstasy) neurotoxicity: 'of mice and men'. IUBMB Life 56: 249-255.
22. Itzhak Y, Ali SF (1996). The neuronal nitric oxide synthase inhibitor, 7-nitroindazole, protects against methamphetamine-induced neurotoxicity in vivo. J Neurochem 67: 1770-1773.
23. Itzhak Y, Ali SF, Achat CN, Anderson KL (2003a). Relevance of MDMA ('ecstasy')-induced neurotoxicity to long-lasting psychomotor stimulation in mice. Psychopharmacology (Berl) 166: 241-248.
24. Itzhak Y, Ali SF, Anderson KL (2003b). Fenfluramine-induced serotonergic neurotoxicity in mice: lack of neuroprotection by inhibition/ablation of nNOS. J Neurochem 87: 268-271.
25. Itzhak Y, Gandia C, Huang PL, Ali SF (1998). Resistance of neuronal nitric oxide synthase-deficient mice to methamphetamine-induced dopaminergic neurotoxicity. J Pharmacol Exp Ther 284: 1040-1047.
26. Itzhak Y, Martin JL, Ali SF (2002). Methamphetamine-induced dopaminergic neurotoxicity in mice: long-lasting sensitization to the locomotor stimulation and desensitization to the rewarding effects of methamphetamine. Prog Neuropsychopharmacol Biol Psychiatry 26: 1177-1183.
27. Kita T, Wagner GC, Nakashima T (2003). Current research on methamphetamine-induced neurotoxicity: animal models of monoamine disruption. J Pharmacol Sci 92: 178-195.
28. Lyles J, Cadet JL (2003). Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: cellular and molecular mechanisms. Brain Res Brain Res Rev 42: 155-168.
29. Marston HM, Reid ME, Lawrence JA, Olverman HJ, Butcher SP (1999). Behavioural analysis of the acute and chronic effects of MDMA treatment in the rat. Psychopharmacology (Berl) 144: 67-76.
30. Martin JL, Itzhak Y (2000). 7-Nitroindazole blocks nicotine-induced conditioned place preference but not LiCl-induced conditioned place aversion. NeuroReport 11: 947-949.
31. McCann UD, Mertl M, Eligulashvili V, Ricaurte GA (1999). Cognitive performance in (±) 3,4-methylene-dioxymethamphetamine (MDMA, 'ecstasy') users: a controlled study. Psychopharmacology 143: 417-425.
32. McCann UD, Szabo Z, Scheffel U, Dannals RF, Ricaurte GA (1998). Positron emission tomographic evidence of toxic effect of MDMA ('Ecstasy') on brain serotonin neurons in human beings. Lancet 352: 1433-1437.
33. Miller DB, O'Callaghan JP (1994). Environment-, drug- and stress-induced alterations in body temperature affect the neurotoxicity of substituted amphetamines in the C57BL/6J mouse. J Pharmacol Exp Ther 270: 752-760.
34. National Research Council (1996). Guide for the Care and Use of Laboratory Animals. National Academy Press: Washington, DC.
35. Olmstead MC, Franklin KB (1996). Differential effects of ventral striatal lesions on the conditioned place preference induced by morphine or amphetamine. Neuroscience 71: 701-708.
36. Packard MG, McGaugh JL (1996). Inactivation of hippocampus or caudate nucleus with lidocaine differentially affects expression of place and response learning. Neurobiol Learn Mem 65: 65-72.
37. Packard MG, Teather LA (1998). Amygdala modulation of multiple memory systems: hippocampus and caudate-putamen. Neurobiol Learn Mem 69: 163-203.
38. Parrott AC, Lees A, Garnham NJ, Jones M, Wesnes K (1998). Cognitive performance in recreational users of MDMA or 'ecstasy': evidence for memory deficits. J Psychopharmacol 12: 79-83.
39. Peat MA, Warren PF, Gibb JW (1983). Effects of a single dose of methamphetamine and iprindole on the serotonergic and dopaminergic system of the rat brain. J Pharmacol Exp Ther 225: 126-131.
40. Pettit HO, Ettenberg A, Bloom FE, Koob GF (1984). Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats. Psychopharmacology (Berl) 84: 167-173.
41. Phillips RG, LeDoux JE (1992). Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behav Neurosci 106: 274-285.
42. Reneman L, Lavalaye J, Schmand B, de Wolff FA, van den Brink W, den Heeten GJ et al (2001). Cortical serotonin transporter density and verbal memory in individuals who stopped using 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy'): preliminary findings. Arch Gen Psychiatry 58: 901-906.
43. Ricaurte GA, Markowska AL, Wenk GL, Hatzidimitriou G, Wlos J, Olton DS (1993). 3,4-Methylenedioxymethamphetamine, serotonin and memory. J Pharmacol Exp Ther 266: 1097-1105.
44. Roberts DC, Koob GF (1982). Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats. Pharmacol Biochem Behav 17: 901-904.
45. Robinson TE, Castaneda E, Whishaw IQ (1993). Effects of cortical serotonin depletion induced by 3,4-methylenedioxymethamphetamine (MDMA) on behavior, before and after additional cholinergic blockade. Neuropsychopharmacology 8: 77-85.
46. Rogers RD, Everitt BJ, Baldacchino A, Blackshaw AJ, Swainson R, Wynne K et al (1999). Dissociable deficits in the decision-making cognition of chronic amphetamine abusers, opiate abusers, patients with focal damage to prefrontal cortex, and tryptophan-depeleted normal volunteers: evidence for monoaminergic mechanisms. Neuropsychopharmacology 20: 322-339.
47. Seiden LS, Sabol KE (1996). Methamphetamine and methylenedioxymethamphetamine neurotoxicty: possible mechanisms of cell destruction. NIDA Res Monogr 163: 251-276.
48. Sellings LH, Clarke PB (2003). Segregation of amphetamine reward and locomotor stimulation between nucleus accumbens medial shell and core. J Neurosci 23: 6295-6303.
49. Semple DM, Ebmeier KP, Glabus MF, O'Carroll RE, Johnstone EC (1999). Reduced in vivo binding to the serotonin transporter in the cerebral cortex of MDMA ('ecstasy') users. Br J Psychiatry 175: 63-69.
50. Simon SL, Domier C, Carnell J, Brethen P, Rawson R, Ling W (2000). Cognitive impairment in individuals currently using methamphetamine. Am J Addict 9: 222-231.
51. Stone DM, Hanson GR, Gibb JW (1987). Differences in the central serotonergic effects of methylenedioxymethamphetamine (MDMA) in mice and rats. Neuropharmacology 26: 1657-1661.
52. Strote J, Lee JE, Wechsler H (2002). Increasing MDMA use among college students: results of a national survey. J Adolesc Health 30: 64-72.
53. Swanson LW, Petrovich GD (1998). What is the amygdala? Trends Neurosci 21: 323-331.
54. Taffe MA, Huitron-Resendiz S, Schroeder R, Parsons LH, Henriksen SJ, Gold LH (2003). MDMA exposure alters cognitive and electrophysiological sensitivity to rapid tryptophan depletion in rhesus monkeys. Pharmacol Biochem Behav 76: 141-152.
55. Thompson PM, Hayashi KM, Simon SL, Geaga JA, Hong MS, Sui Y et al (2004). Structural abnormalities in the brains of human subjects who use methamphetamine. J Neurosci 24: 6028-6036.
56. Verkes RJ, Gijsman HJ, Pieters MS, Schoemaker RC, de Visser S, Kuijpers M et al (2001). Cognitive performance and serotonergic function in users of ecstasy. Psychopharmacology (Berl) 153: 196-202.
57. Volkow ND, Chang L, Wang GJ, Fowler JS, Franceschi D, Sedler M et al (2001a). Loss of dopamine transporters in methamphetamine abusers recovers with protracted abstinence. J Neurosci 21: 9414-9418.
58. Volkow ND, Chang L, Wang GJ, Fowler JS, Leonido-Yee M, Franceschi D et al (2001b). Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers. Am J Psychiatry 158: 377-382.
59. Vorhees CH, Inman-Wood SL, Morford LL, Broening HW, Fukumura M, Moran MS (2000). Adult learning deficits after neonatal exposure to D-methamphetamine: selective effects on spatial navigation and memory. J Neurosci 20: 4732-4739.