Fenfluramine-induced serotonergic neurotoxicity in mice: Lack of neuroprotection by inhibition/ablation of nNOS

Journal of Neurochemistry

Volumn 87, Issue 1, 2003, Pages 268-271

  Itzhak, Yossef ^a,c   Alit, Syed F ^b   Anderson, Karen L ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^c FLORIDA INTERNATIONAL UNIVERSITY   (United States)

Author keywords

7 nitroindazole; Fenfluramine; Methamphetamine; Nitric oxide; Serotonergic and dopaminergic neurotoxicity

Indexed keywords

7 NITROINDAZOLE; AMPHETAMINE; FENFLURAMINE; METHAMPHETAMINE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; SEROTONIN; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; FRONTAL CORTEX; HIPPOCAMPUS; HYPOTHERMIA; MALE; MOUSE; MOUSE STRAIN; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SEROTONINERGIC NERVE CELL; THERMOREGULATION; WILD TYPE;

ANIMALS; BIOLOGICAL MARKERS; BODY TEMPERATURE; CARRIER PROTEINS; CORPUS STRIATUM; ENZYME INHIBITORS; FENFLURAMINE; FRONTAL LOBE; HIPPOCAMPUS; HYPOTHERMIA; INDAZOLES; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEURONS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN UPTAKE INHIBITORS;

ANIMALIA;

EID: 0141531062     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02023.x     Document Type: Article

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