The neuronal nitric oxide synthase inhibitor, 7-nitroindazole, protects against methamphetamine-induced neurotoxicity in vivo

Journal of Neurochemistry

Volumn 67, Issue 4, 1996, Pages 1770-1773

  Itzhak, Yossef ^a   Ali, Syed F ^b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b Natl Ctr Toxicological Res F   (United States)

Author keywords

7 Nitroindazole; Dopamine; Methamphetamine; Neurotoxicity; Nitric oxide synthase

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; 7 NITROINDAZOLE; HOMOVANILLIC ACID; MAZINDOL; METHAMPHETAMINE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CELL DEATH; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; IN VIVO STUDY; NEUROTOXICITY; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0029789902     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.67041770.x     Document Type: Article

References (27)

1. Ali S. F., Newport G. D., Holson R. R., Slikker W. Jr., and Bowyer J. F. (1994) Low environmental temperature or pharmacologic agents that produce hypothermia decrease methamphetamine neurotoxicity in mice. Brain Res. 658, 33-38.
2. Beckman J. S., Beckman T. W., Chen J., Marshall P. M., and Freeman B. A. (1990) Apparent hydroxy radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. USA 87, 1621-1624.
3. Bowyer J. F., Tank A. W., Newport G. D., Slikker W. Jr., Ali S. F., and Holson R. R. (1992) The influence of environmental temperature on the transient effects of methamphetamine on dopamine levels and dopamine release in rat striatum. J. Pharmacol. Exp. Ther. 260, 817-824.
4. Dawson V. L., Dawson T. M., Bartley D. A., Uhl G. R., and Snyder S. H. (1993) Mechanisms of nitric-oxide mediated neurotoxicity in primary brain cultures. J. Neurosci. 13, 2651-2661.
5. De Vito M. J. and Wagner G. C. (1989) Methamphetamine-induced neuronal damage: a possible role for free radicals. Neuropharmacology 28, 1145-1150.
6. Fuller R. W. and Hemrick-Luecke S. (1980) Long-lasting depletion of striatal dopamine by a single injection of amphetamine in iprindole-treated rats. Science 209, 305-307.
7. Garthwaite J. (1991) Glutamate, nitric oxide, and cell-cell signalling. Trends Neurosci. 14, 60-67.
8. Itzhak Y. (1996) Attenuation of cocaine kindling by 7-nitroindazole, an inhibitor of brain nitric oxide synthase. Neuropharmacology (in press).
9. Karler R., Calder L. D., Chaudhry I. A., and Turkanis S. A. (1989) Blockade of "reverse tolerance" to cocaine and amphetamine by MK-801. Life Sci. 45, 599-606.
10. Kogan F. J., Nichols W. K., and Gibb J. W. (1976) Influence of methamphetamine on nigral and striatal tyrosine hydroxylase activity and on striatal dopamine levels. Eur. J. Pharmacol. 36, 363-371.
11. 3H]dopamine release from striatal slices. J. Neurosci. Res. 35, 192-198.
12. Lowry O. H., Rosebrough N. J., Farr A. L., and Randall R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275.
13. Miller D. B. and O'Callaghan J. P. (1994) Environmental-, drug- and stress-induced alterations in body temperature affect the neurotoxicity of substituted amphetamine in the C57BL/6J mouse. J. Pharmacol. Exp. Ther. 270, 752-760.
14. Moore P. K., Babbedge R. C., Wallace P., Gaffen Z. A., and Hart S. L. (1993) 7-Nitroindazole, an inhibitor of nitric oxide synthase, exhibits anti-nociceptive activity in the mouse without increasing blood pressure. Br. J. Pharmacol. 108, 296-297.
15. Nash J. F. and Yamamoto B. K. (1992) Methamphetamine neurotoxicity and striatal glutamate release: comparison to 3,4-methylenedioxymethamphetamine. Brain Res. 581, 237-243.
16. Ohno M, and Watanabe S. (1995) Nitric oxide synthase inhibitors block behavioral sensitization to methamphetamine in mice. Eur. J. Pharmacol. 275, 39-44.
17. Przedborski S., Jackson-Lewis V., Yokoyama R., Shibata T., Dawson V. L., and Dawson T. M. (1996) Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Proc. Natl. Acad. Sci. USA 93, 4565-4571.
18. Schulz J. B., Matthews R. T., Muqit M. M. K., Browne S. E., and Beal M. F. (1995) Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice. J. Neurochem. 64, 936-939.
19. Sheng P., Cerruit C., Ali S. F., and Cadet J. L. (1996) Nitric oxide is a mediator of methamphetamine (METH)-induced neurotoxicity: in vitro evidence from primary cultures of mesencephalic cells. Ann. NY Acad. Sci. (in press).
20. Shibata M., Araki N., Ohta K., Hamada J., Shimazu K., and Fukuuchi Y. (1996) Nitric oxide regulates NMDA-induced dopamine release in the striatum. Neuroreport 7, 605-608.
21. Silva M. T., Rose S., Hindmarsh J. G., Aislaitner G., Gorrod J. W., Moore P. K., Jenner P., and Marsden C. D. (1995) Increased striatal dopamine efflux in vivo following inhibition of cerebral nitric oxide synthase by novel monosodium salt of 7-nitroindazole. Br. J. Pharmacol. 114, 257-258.
22. Snyder S. H. (1992) Nitric oxide: first in a new class of neurotransmitters? Science 257, 494-496.
23. Sonsalla P. K., Nicklas W. J., and Heikkila R. E. (1989) Role of excitatory amino acids in methamphetamine induced nigrostriatal dopaminergic toxicity. Science 243, 398-400.
24. Strasser A., McCarron R. M., Ishii H., Stanimirovic D., and Spatz M. (1994) L-Arginine induces dopamine release from the striatum in vivo. Neuroreport 5, 2298-2300.
25. Wagner G. C., Ricaurte G. A., Seiden L. S., Schuster C. R., Miller R. J., and Westley J. (1980) Long-lasting depletion of striatal dopamine and loss of dopamine uptake sites following repeated administration of methamphetamine. Brain Res. 181, 151-160.
26. Zhang J., Dawson V. L., Dawson T. M., and Snyder S. H. (1994) Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science 263, 687-689.
27. Zhu X.-Z. and Luo L.-G. (1992) Effect of nitroprusside (nitric oxide) on endogenous dopamine release from rat striatal slices. J. Neurochem. 59, 932-935.