-
1
-
-
0014545138
-
Vascular pathology of homocysteinemia: Implications for the pathogenesis of arteriosclerosis
-
McCully KS. Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. Am J Pathol 1969;56:111-28.
-
(1969)
Am J Pathol
, vol.56
, pp. 111-128
-
-
McCully, K.S.1
-
2
-
-
0037163003
-
Homocysteine is a protein amino acid in humans
-
Jakubowski H. Homocysteine is a protein amino acid in humans. J Biol Chem 2002;277:30425-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 30425-30428
-
-
Jakubowski, H.1
-
3
-
-
9144225352
-
Facts and recommendations about total homocysteine determinations: An expert opinion
-
Refsum H, Smith AD, Ueland PM, Nexo E, Clarke R, McPartlin J, et al. Facts and recommendations about total homocysteine determinations: an expert opinion. Clin Chem 2004;50:3-32.
-
(2004)
Clin Chem
, vol.50
, pp. 3-32
-
-
Refsum, H.1
Smith, A.D.2
Ueland, P.M.3
Nexo, E.4
Clarke, R.5
McPartlin, J.6
-
4
-
-
1842331509
-
Plasma homocysteine as a risk factor for vascular disease: The European Concerted Action Project
-
Graham I, Daly LE, Refsum HM, Robinson K, Brattstrom LE, Ueland PM, et al. Plasma homocysteine as a risk factor for vascular disease: the European Concerted Action Project. JAMA 1997;277:1775-81.
-
(1997)
JAMA
, vol.277
, pp. 1775-1781
-
-
Graham, I.1
Daly, L.E.2
Refsum, H.M.3
Robinson, K.4
Brattstrom, L.E.5
Ueland, P.M.6
-
5
-
-
19044374147
-
Disorders of sulfur amino acid metabolism
-
Fernandes J, Saudubray J-M, van den Berghe G, Walter JH, editors. Springer
-
Andria G, Fowler B, Sebastio G. Disorders of sulfur amino acid metabolism. In: Fernandes J, Saudubray J-M, van den Berghe G, Walter JH, editors. Inborn metabolic diseases - diagnosis and treatment. 3th ed. Springer; 2000. p. 223-32.
-
(2000)
Inborn Metabolic Diseases - Diagnosis and Treatment. 3th Ed.
, pp. 223-232
-
-
Andria, G.1
Fowler, B.2
Sebastio, G.3
-
6
-
-
0029049553
-
A candidate genetic risk factor for vascular disease: A common methylenetetrahydrofolate reductase mutation causes thermoinstability
-
Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, et al. A candidate genetic risk factor for vascular disease: a common methylenetetrahydrofolate reductase mutation causes thermoinstability. Nat Genet 1995;10:111-3.
-
(1995)
Nat Genet
, vol.10
, pp. 111-113
-
-
Frosst, P.1
Blom, H.J.2
Milos, R.3
Goyette, P.4
Sheppard, C.A.5
Matthews, R.G.6
-
7
-
-
0032895522
-
The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia
-
Guenther BD, Sheppard CA, Tran P, Rozen R, Matthews RG, Ludwig ML. The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia. Nat Struct Biol 1999;6:359-65.
-
(1999)
Nat Struct Biol
, vol.6
, pp. 359-365
-
-
Guenther, B.D.1
Sheppard, C.A.2
Tran, P.3
Rozen, R.4
Matthews, R.G.5
Ludwig, M.L.6
-
8
-
-
0041326346
-
Geographical and ethnic variation of the 677C>T allele of 5,10 methylenetetrahydrofolate reductase (MTHFR): Findings from over 7000 newborns from 16 areas world wide
-
Wilcken B, Bamforth F, Li Z, Zhu H, Ritvanen A, Renlund M, et al. Geographical and ethnic variation of the 677C>T allele of 5,10 methylenetetrahydrofolate reductase (MTHFR): findings from over 7000 newborns from 16 areas world wide. J Med Genet 2003;40:619-25.
-
(2003)
J Med Genet
, vol.40
, pp. 619-625
-
-
Wilcken, B.1
Bamforth, F.2
Li, Z.3
Zhu, H.4
Ritvanen, A.5
Renlund, M.6
-
9
-
-
0032497941
-
Common methylenetetrahydrofolate reductase gene mutation leadsto hyperhomocysteinemia but not to vascular disease: The result of a meta-analysis
-
Brattstrom L, Wilcken DE, Ohrvik J, Brudin L. Common methylenetetrahydrofolate reductase gene mutation leadsto hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis. Circulation 1998;98:2520-6.
-
(1998)
Circulation
, vol.98
, pp. 2520-2526
-
-
Brattstrom, L.1
Wilcken, D.E.2
Ohrvik, J.3
Brudin, L.4
-
10
-
-
0027382008
-
Vitamin status and intake as primary determinants of homocysteinemia in the elderly
-
Selhub J, Jacques PF, Wilson PWF, Rush D, Rosenberg IH. Vitamin status and intake as primary determinants of homocysteinemia in the elderly. JAMA 1993;270:2693-8.
-
(1993)
JAMA
, vol.270
, pp. 2693-2698
-
-
Selhub, J.1
Jacques, P.F.2
Wilson, P.W.F.3
Rush, D.4
Rosenberg, I.H.5
-
11
-
-
0036140785
-
Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering
-
Doshi SN, McDowell IFW, Moat SJ, Payne N, Durrant HJ, Lewis MJ, Goodfellow J. Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering. Circulation 2002;105:22-6.
-
(2002)
Circulation
, vol.105
, pp. 22-26
-
-
Doshi, S.N.1
McDowell, I.F.W.2
Moat, S.J.3
Payne, N.4
Durrant, H.J.5
Lewis, M.J.6
Goodfellow, J.7
-
12
-
-
0037132839
-
Importance of both folic acid and vitamin B12 in reduction of risk of vascular disease
-
Quinlivan EP, McPartlin J, McNulty H, Ward M, Strain JJ, Weir DG, et al. Importance of both folic acid and vitamin B12 in reduction of risk of vascular disease. Lancet 2002;359:227-8.
-
(2002)
Lancet
, vol.359
, pp. 227-228
-
-
Quinlivan, E.P.1
McPartlin, J.2
McNulty, H.3
Ward, M.4
Strain, J.J.5
Weir, D.G.6
-
13
-
-
0036305521
-
Vitamin B12 status is inversely associated with plasma homocysteine in young women with C677T and/or A1298C methylenetetrahydrofolate reductase polymorphisms
-
Bailey LB, Duhaney RL, Maneval DR, Kauwell GP, Quinlivan EP, Davis SR, et al. Vitamin B12 status is inversely associated with plasma homocysteine in young women with C677T and/or A1298C methylenetetrahydrofolate reductase polymorphisms. J Nutr 2002;132:1872-8.
-
(2002)
J Nutr
, vol.132
, pp. 1872-1878
-
-
Bailey, L.B.1
Duhaney, R.L.2
Maneval, D.R.3
Kauwell, G.P.4
Quinlivan, E.P.5
Davis, S.R.6
-
14
-
-
0038446637
-
Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults
-
Kluijtmans LAJ, Young IS, Colin A, Murray L, McMaster D, McNulty H, et al. Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults. Blood 2003;101:2483-8.
-
(2003)
Blood
, vol.101
, pp. 2483-2488
-
-
Kluijtmans, L.A.J.1
Young, I.S.2
Colin, A.3
Murray, L.4
McMaster, D.5
McNulty, H.6
-
15
-
-
0032104612
-
Periconceptional folic acid containing multivitamin supplementation
-
Czeizel AE. Periconceptional folic acid containing multivitamin supplementation. Eur J Obstet Gynecol Reprod Biol 1998;78:151-61.
-
(1998)
Eur J Obstet Gynecol Reprod Biol
, vol.78
, pp. 151-161
-
-
Czeizel, A.E.1
-
16
-
-
0034190437
-
Occurrence of congenital heart defects in relation to maternal mulitivitamin use
-
Botto LD, Mulinare J, Erickson JD. Occurrence of congenital heart defects in relation to maternal mulitivitamin use. Am J Epidemiol 2000;151:878-84.
-
(2000)
Am J Epidemiol
, vol.151
, pp. 878-884
-
-
Botto, L.D.1
Mulinare, J.2
Erickson, J.D.3
-
17
-
-
0028799948
-
Maternal periconceptional use of multivitamins and reduced risk for conotruncal heart defects and limb deficiencies among offspring
-
Shaw GM, O'Malley CD, Wasserman CR, Tolarova MM, Lammer EJ. Maternal periconceptional use of multivitamins and reduced risk for conotruncal heart defects and limb deficiencies among offspring. Am J Med Genet 1995;59:536-45.
-
(1995)
Am J Med Genet
, vol.59
, pp. 536-545
-
-
Shaw, G.M.1
O'Malley, C.D.2
Wasserman, C.R.3
Tolarova, M.M.4
Lammer, E.J.5
-
18
-
-
0031975890
-
Preconceptional folate intake and malformations of the cardiac outflow tract
-
Baltimore-Washington Infant Study Group
-
Scanlon KS, Ferencz C, Loffredo CA, Wilson PD, Correa-Villasenor A, Khoury MJ, et al. Preconceptional folate intake and malformations of the cardiac outflow tract. Baltimore-Washington Infant Study Group. Epidemiology 1998;9:95-8.
-
(1998)
Epidemiology
, vol.9
, pp. 95-98
-
-
Scanlon, K.S.1
Ferencz, C.2
Loffredo, C.A.3
Wilson, P.D.4
Correa-Villasenor, A.5
Khoury, M.J.6
-
19
-
-
0029022223
-
Reduced recurrence of orofacial clefts after periconceptional supplementation with high-dose folic acid and multivitamins
-
Tolarova M, Harris J. Reduced recurrence of orofacial clefts after periconceptional supplementation with high-dose folic acid and multivitamins. Teratology 1995;51:71-8.
-
(1995)
Teratology
, vol.51
, pp. 71-78
-
-
Tolarova, M.1
Harris, J.2
-
20
-
-
0029151571
-
Risks of orofacial clefts in children born to women using multivitamins containing folic acid periconceptionally
-
Shaw GM, Lammer EJ, Wasserman CR, O'Malley CD, Tolarova MM. Risks of orofacial clefts in children born to women using multivitamins containing folic acid periconceptionally. Lancet 1995;346:393-6.
-
(1995)
Lancet
, vol.346
, pp. 393-396
-
-
Shaw, G.M.1
Lammer, E.J.2
Wasserman, C.R.3
O'Malley, C.D.4
Tolarova, M.M.5
-
22
-
-
0035119022
-
Maternal multivitamin use and orofacial clefts in offspring
-
Itikala PR, Watkins ML, Mulinare J, Moore CA, Liu Y. Maternal multivitamin use and orofacial clefts in offspring. Teratology 2001;63:79-86.
-
(2001)
Teratology
, vol.63
, pp. 79-86
-
-
Itikala, P.R.1
Watkins, M.L.2
Mulinare, J.3
Moore, C.A.4
Liu, Y.5
-
23
-
-
0033213972
-
Multivitamin supplementation and risk of birth defects
-
Werler MM, Hayes C, Louik C, Shapiro S, Mitchell AA. Multivitamin supplementation and risk of birth defects. Am J Epidemiol 1999;150:675-82.
-
(1999)
Am J Epidemiol
, vol.150
, pp. 675-682
-
-
Werler, M.M.1
Hayes, C.2
Louik, C.3
Shapiro, S.4
Mitchell, A.A.5
-
24
-
-
0031049636
-
Does periconceptional multivitamin use reduce the risk for limb deficiency in offspring?
-
Yang Q, Khoury MJ, Olney RS, Mulinare J. Does periconceptional multivitamin use reduce the risk for limb deficiency in offspring? Epidemiology 1997;8:157-61.
-
(1997)
Epidemiology
, vol.8
, pp. 157-161
-
-
Yang, Q.1
Khoury, M.J.2
Olney, R.S.3
Mulinare, J.4
-
25
-
-
0028911977
-
Periconceptional multivitamin use in relation to the risk of congenital urinary tract anomalies
-
Li DK, Daling JR, Mueller BA, Hickok DE, Fantel AG, Weiss NS. Periconceptional multivitamin use in relation to the risk of congenital urinary tract anomalies. Epidemiology 1995;6:212-8.
-
(1995)
Epidemiology
, vol.6
, pp. 212-218
-
-
Li, D.K.1
Daling, J.R.2
Mueller, B.A.3
Hickok, D.E.4
Fantel, A.G.5
Weiss, N.S.6
-
26
-
-
0036247283
-
Occurrence of omphalocele in relation to maternal multivitamin use: A population-based study
-
Botto LD, Mulinare J, Erickson JD. Occurrence of omphalocele in relation to maternal multivitamin use: a population-based study. Pediatrics 2002;109:904-8.
-
(2002)
Pediatrics
, vol.109
, pp. 904-908
-
-
Botto, L.D.1
Mulinare, J.2
Erickson, J.D.3
-
27
-
-
0942287359
-
Vitamin supplements and the risk for congenital anomalies other than neural tube defects
-
Botto LD, Olney RS, Erickson JD. Vitamin supplements and the risk for congenital anomalies other than neural tube defects. Am J Med Genet 2004;125:12-21.
-
(2004)
Am J Med Genet
, vol.125
, pp. 12-21
-
-
Botto, L.D.1
Olney, R.S.2
Erickson, J.D.3
-
28
-
-
50549208782
-
Folic acid metabolism and human embryopathy
-
Hibbard ED, Smithells RW. Folic acid metabolism and human embryopathy. Lancet 1965;1:1254.
-
(1965)
Lancet
, vol.1
, pp. 1254
-
-
Hibbard, E.D.1
Smithells, R.W.2
-
29
-
-
0025863475
-
Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study
-
Medical Research Council Vitamin Study Research Group. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet 1991;338:131-7.
-
(1991)
Lancet
, vol.338
, pp. 131-137
-
-
-
30
-
-
0027080461
-
Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation
-
Czeizel AE, Dudas I. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med 1992;327:1832-5.
-
(1992)
N Engl J Med
, vol.327
, pp. 1832-1835
-
-
Czeizel, A.E.1
Dudas, I.2
-
31
-
-
0028149224
-
Maternal hyperhomocysteinemia: A risk factor for neural-tube defects?
-
Steegers-Theunissen RPM, Boers GHJ, Trijbels JMF, Finkelstein JD, Blom HJ, Thomas CM, et al. Maternal hyperhomocysteinemia: a risk factor for neural-tube defects? Metabolism 1994;43:1475-80.
-
(1994)
Metabolism
, vol.43
, pp. 1475-1480
-
-
Steegers-Theunissen, R.P.M.1
Boers, G.H.J.2
Trijbels, J.M.F.3
Finkelstein, J.D.4
Blom, H.J.5
Thomas, C.M.6
-
32
-
-
0028833677
-
Homocysteine metabolism in pregnancies complicated by neural-tube defects
-
Mills JL, McPartlin JM, Kirke PN, Lee YJ, Conley MR, Weir DG, et al. Homocysteine metabolism in pregnancies complicated by neural-tube defects. Lancet 1995;345:149-51.
-
(1995)
Lancet
, vol.345
, pp. 149-151
-
-
Mills, J.L.1
McPartlin, J.M.2
Kirke, P.N.3
Lee, Y.J.4
Conley, M.R.5
Weir, D.G.6
-
33
-
-
0030463010
-
Homocysteine induces congenital defects of the heart and neural tube: Effect of folic acid
-
Rosenquist TH, Ratashak SA, Selhub J. Homocysteine induces congenital defects of the heart and neural tube: effect of folic acid. Proc Natl Acad Sci U S A 1996;93:15227-32.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 15227-15232
-
-
Rosenquist, T.H.1
Ratashak, S.A.2
Selhub, J.3
-
34
-
-
0032884078
-
Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development
-
Piedrahita JA, Oetama B, Bennett GD, van Waes J, Kamen BA, Richardson J, et al. Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development. Nat Genet 1999;23:228-32.
-
(1999)
Nat Genet
, vol.23
, pp. 228-232
-
-
Piedrahita, J.A.1
Oetama, B.2
Bennett, G.D.3
Van Waes, J.4
Kamen, B.A.5
Richardson, J.6
-
35
-
-
1942469552
-
Gene-gene interaction in folate-related genes and risk of neural tube defects in a UK population
-
Relton CL, Wilding CS, Pearce MS, Laffling AJ, Jonas PA, Lynch SA, et al. Gene-gene interaction in folate-related genes and risk of neural tube defects in a UK population. J Med Genet 2004;41:256-60.
-
(2004)
J Med Genet
, vol.41
, pp. 256-260
-
-
Relton, C.L.1
Wilding, C.S.2
Pearce, M.S.3
Laffling, A.J.4
Jonas, P.A.5
Lynch, S.A.6
-
36
-
-
3042784787
-
Impact of the MTHFR C677T polymorphism on risk of neural tube defects: Case-control study
-
Kirke PN, Mills JL, Molloy AM, Brody LC, O'Leary VB, Daly L, et al. Impact of the MTHFR C677T polymorphism on risk of neural tube defects: case-control study. Br Med J 2004;328:1535-6.
-
(2004)
Br Med J
, vol.328
, pp. 1535-1536
-
-
Kirke, P.N.1
Mills, J.L.2
Molloy, A.M.3
Brody, L.C.4
O'Leary, V.B.5
Daly, L.6
-
37
-
-
0034190659
-
5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: A HuGE review
-
Botto LD, Yang Q. 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. Am J Epidemiol 2000;151:862-77.
-
(2000)
Am J Epidemiol
, vol.151
, pp. 862-877
-
-
Botto, L.D.1
Yang, Q.2
-
38
-
-
0031971515
-
A second common mutation in the methylenetetrahydrofolate reductase gene: An additional risk factor for neural-tube defects?
-
van der Put NM, Gabreels F, Stevens EM, Smeitink JA, Trijbels FJ, Eskes TK, et al. A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? Am J Hum Genet 1998;62:1044-51.
-
(1998)
Am J Hum Genet
, vol.62
, pp. 1044-1051
-
-
Van Der Put, N.M.1
Gabreels, F.2
Stevens, E.M.3
Smeitink, J.A.4
Trijbels, F.J.5
Eskes, T.K.6
-
39
-
-
0032856882
-
A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida
-
Wilson A, Platt R, Wu Q, Leclerc D, Christensen B, Yang H, et al. A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida. Mol Genet Metab 1999;67:317-23.
-
(1999)
Mol Genet Metab
, vol.67
, pp. 317-323
-
-
Wilson, A.1
Platt, R.2
Wu, Q.3
Leclerc, D.4
Christensen, B.5
Yang, H.6
-
40
-
-
0242669376
-
Reduced folate carrier polymorphism (80A→G) and neural tube defects
-
De Marco P, Calevo MG, Moroni A, Merello E, Raso A, Finnell RH, et al. Reduced folate carrier polymorphism (80A→G) and neural tube defects. Eur J Hum Genet 2003;11:245-52.
-
(2003)
Eur J Hum Genet
, vol.11
, pp. 245-252
-
-
De Marco, P.1
Calevo, M.G.2
Moroni, A.3
Merello, E.4
Raso, A.5
Finnell, R.H.6
-
41
-
-
18644379774
-
A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: Report of the Birth Defects Research Group
-
Brody LC, Conley M, Cox C, Kirke PN, McKeever MP, Mills JL, et al. A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defects Research Group. Am J Hum Genet 2002;71:1207-15.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 1207-1215
-
-
Brody, L.C.1
Conley, M.2
Cox, C.3
Kirke, P.N.4
McKeever, M.P.5
Mills, J.L.6
-
42
-
-
0038549053
-
Folic acid supplements and fortification affect the risk for neural tube defects, vascular disease and cancer: Evolving science
-
Bailey LB, Rampersaud GC, Kauwell GPA. Folic acid supplements and fortification affect the risk for neural tube defects, vascular disease and cancer: evolving science. J Nutr 2003;133:1961S-8S.
-
(2003)
J Nutr
, vol.133
-
-
Bailey, L.B.1
Rampersaud, G.C.2
Kauwell, G.P.A.3
-
43
-
-
2342631856
-
Spina bifida and anencephaly before and after folic acid mandate-United States, 1995-1996 and 1999-2000
-
CDC. Spina bifida and anencephaly before and after folic acid mandate-United States, 1995-1996 and 1999-2000. MMWR 2004;53:362-5.
-
(2004)
MMWR
, vol.53
, pp. 362-365
-
-
-
44
-
-
0033551352
-
The effect of folic acid fortification on plasma folate and total homocysteine concentrations
-
Jacques PF, Selhub J, Bostom AG, Wilson PWF, Rosenberg IH. The effect of folic acid fortification on plasma folate and total homocysteine concentrations. N Engl J Med 1999;340:1449-54.
-
(1999)
N Engl J Med
, vol.340
, pp. 1449-1454
-
-
Jacques, P.F.1
Selhub, J.2
Bostom, A.G.3
Wilson, P.W.F.4
Rosenberg, I.H.5
-
45
-
-
0030695338
-
Folate intake in Europe: Recommended, actual and desired intake
-
de Bree A, van Dusseldorp M, Brouwer IA, van het Hof KH, Steegers-Theunissen RP. Folate intake in Europe: recommended, actual and desired intake. Eur J Clin Nutr 1997;51:643-60.
-
(1997)
Eur J Clin Nutr
, vol.51
, pp. 643-660
-
-
De Bree, A.1
Van Dusseldorp, M.2
Brouwer, I.A.3
Van Het Hof, K.H.4
Steegers-Theunissen, R.P.5
-
46
-
-
3142691181
-
Modeling the level of fortification and post-fortification assessments: US experience
-
Yetley EA, Rader JI. Modeling the level of fortification and post-fortification assessments: US experience. Nutr Rev 2004;62:S50-9.
-
(2004)
Nutr Rev
, vol.62
-
-
Yetley, E.A.1
Rader, J.I.2
-
47
-
-
0011509017
-
-
The Hague: Netherlands Heart Foundation; in Dutch
-
Netherlands Heart Foundation. Homocysteine and cardiovascular disease. The Hague: Netherlands Heart Foundation; 2001 (in Dutch).
-
(2001)
Homocysteine and Cardiovascular Disease
-
-
|