Over-expression of the human EAAT2 glutamate transporter within neurons of mouse organotypic hippocampal slice cultures leads to increased vulnerability of CA1 pyramidal cells

European Journal of Neuroscience

Volumn 21, Issue 8, 2005, Pages 2291-2296

  Selkirk, Julie V ^a   Stiefel, Theodore H ^a   Stone, Ida M ^b   Naeve, Greg S ^a   Foster, Alan C ^a   Poulsen, David J ^b  

^a NEUROCRINE BIOSCIENCES INC   (United States)

^b UNIVERSITY OF MONTANA   (United States)

Author keywords

Adeno associated virus; Glutamate transport; Hippocampus; Neuronal degeneration; Organotypic slice culture

Indexed keywords

EXCITATORY AMINO ACID TRANSPORTER; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; NEURON SPECIFIC ENOLASE;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; EXCITOTOXICITY; GENE CASSETTE; GENE EXPRESSION; GENE OVEREXPRESSION; HIPPOCAMPUS; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NERVE CELL LESION; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RAT; TISSUE CULTURE;

AMINO ACID TRANSPORT SYSTEM X-AG; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ASPARTIC ACID; BLOTTING, WESTERN; CELL DEATH; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EXCITATORY AMINO ACID TRANSPORTER 2; GENE EXPRESSION; GLUTAMATE PLASMA MEMBRANE TRANSPORT PROTEINS; GLUTAMIC ACID; GREEN FLUORESCENT PROTEINS; HIPPOCAMPUS; HUMANS; KAINIC ACID; MICE; NEUROGLIA; ORGAN CULTURE TECHNIQUES; PHOSPHOPYRUVATE HYDRATASE; PYRAMIDAL CELLS; SYMPORTERS; TIME FACTORS; TRANSDUCTION, GENETIC; TRITIUM;

EID: 18844460393     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2005.04059.x     Document Type: Article

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