Evidence for two atypical conformations of beta-adrenoceptors and their interaction with Gi proteins

European Journal of Pharmacology

Volumn 513, Issue 1-2, 2005, Pages 109-118

  Santos, Iraídes N ^a   Sumitame, Marie ^a   Caceres, Viviane M ^a   Moreira, Marilia F ^a   Krieger, Marta H ^a   Spadari Bratfisch, Regina C ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

1 Adrenoceptor; 4 Adrenoceptor; CGP12177; Sinoaortic denervation

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; 5 [2 [[2 HYDROXY 3 [4 (1 METHYL 4 TRIFLUOROMETHYL 2 IMIDAZOLYL)PHENOXY]PROPYL]AMINO]ETHOXY]SALICYLAMIDE; BETA ADRENERGIC RECEPTOR; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; NORADRENALIN; PERTUSSIS TOXIN; PROPRANOLOL; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA SINUS; ARTICLE; CARDIOVASCULAR RESPONSE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DESENSITIZATION; DRUG BINDING SITE; DRUG SENSITIVITY; HEART ATRIUM; HEART DENERVATION; MALE; MOLECULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; RAT;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HEART; HEART ATRIA; IMIDAZOLES; ISOPROTERENOL; MALE; MYOCARDIAL CONTRACTION; NOREPINEPHRINE; PERTUSSIS TOXIN; PROPANOLAMINES; PROTEIN BINDING; PROTEIN CONFORMATION; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, ADRENERGIC, BETA-1;

EID: 18844374176     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.03.008     Document Type: Article

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