메뉴 건너뛰기




Volumn 163, Issue 1-2, 2005, Pages 84-91

Vascular endothelial growth factor is regulated by hypoxic stress via MAPK and HIF-1α in the inner ear

Author keywords

Hair cells; Hypoxia; Hypoxia inducible factor 1 ; Mitogen activated protein kinase; Vascular endothelial growth factor

Indexed keywords

DEFEROXAMINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IRON; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; VASCULOTROPIN;

EID: 18844373918     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2005.02.019     Document Type: Article
Times cited : (10)

References (47)
  • 1
    • 0036132872 scopus 로고    scopus 로고
    • C-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription
    • A. Alfranca, M.D. Gutierrez, A. Vara, J. Aragones, F. Vidal, and M.O. Landazuri c-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription Mol. Cell. Biol. 22 2002 12 22
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 12-22
    • Alfranca, A.1    Gutierrez, M.D.2    Vara, A.3    Aragones, J.4    Vidal, F.5    Landazuri, M.O.6
  • 2
    • 0037099159 scopus 로고    scopus 로고
    • Hypoxia-induced cell death and changes in hypoxia-inducible factor-1 activity in PC12 cells upon exposure to nerve growth factor
    • N. Charlier, N. Leclere, U. Felderhoff, J. Heldt, T. Kietzmann, M. Obladen, and J. Gross Hypoxia-induced cell death and changes in hypoxia-inducible factor-1 activity in PC12 cells upon exposure to nerve growth factor Brain Res. Mol. Brain Res. 104 2002 21 30
    • (2002) Brain Res. Mol. Brain Res. , vol.104 , pp. 21-30
    • Charlier, N.1    Leclere, N.2    Felderhoff, U.3    Heldt, J.4    Kietzmann, T.5    Obladen, M.6    Gross, J.7
  • 3
    • 0036803646 scopus 로고    scopus 로고
    • Effect of hypoxia on noise-induced auditory impairment
    • G.D. Chen Effect of hypoxia on noise-induced auditory impairment Hear. Res. 172 2002 186 195
    • (2002) Hear. Res. , vol.172 , pp. 186-195
    • Chen, G.D.1
  • 5
    • 0033551609 scopus 로고    scopus 로고
    • Selective activation of p38alpha and p38gamma by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cells
    • P.W. Conrad, R.T. Rust, J. Han, D.E. Millhorn, and D. Beitner-Johnson Selective activation of p38alpha and p38gamma by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cells J. Biol. Chem. 274 1999 23570 23576
    • (1999) J. Biol. Chem. , vol.274 , pp. 23570-23576
    • Conrad, P.W.1    Rust, R.T.2    Han, J.3    Millhorn, D.E.4    Beitner-Johnson, D.5
  • 6
    • 0037470189 scopus 로고    scopus 로고
    • Evidence for a role of p38 kinase in hypoxia-inducible factor 1-independent induction of vascular endothelial growth factor expression by sodium arsenite
    • M.C. Duyndam, S.T. Hulscher, E. van der Wall, H.M. Pinedo, and E. Boven Evidence for a role of p38 kinase in hypoxia-inducible factor 1-independent induction of vascular endothelial growth factor expression by sodium arsenite J. Biol. Chem. 278 2003 6885 6895
    • (2003) J. Biol. Chem. , vol.278 , pp. 6885-6895
    • Duyndam, M.C.1    Hulscher, S.T.2    Van Der Wall, E.3    Pinedo, H.M.4    Boven, E.5
  • 7
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • N. Ferrara, H.P. Gerber, and J. LeCouter The biology of VEGF and its receptors Nat. Med. 9 2003 669 676
    • (2003) Nat. Med. , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    Lecouter, J.3
  • 9
    • 0034647933 scopus 로고    scopus 로고
    • Antioxidant/pro-oxidant equilibrium regulates HIF-1alpha and NF-kappa B redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells
    • J.J. Haddad, R.E. Olver, and S.C. Land Antioxidant/pro-oxidant equilibrium regulates HIF-1alpha and NF-kappa B redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells J. Biol. Chem. 275 2000 21130 21139
    • (2000) J. Biol. Chem. , vol.275 , pp. 21130-21139
    • Haddad, J.J.1    Olver, R.E.2    Land, S.C.3
  • 11
    • 0036223298 scopus 로고    scopus 로고
    • Role of Ca(2+) on TNF-alpha and IL-6 secretion from RBL-2H3 mast cells
    • H.J. Jeong, S.H. Hong, D.J. Lee, J.H. Park, K.S. Kim, and H.M. Kim Role of Ca(2+) on TNF-alpha and IL-6 secretion from RBL-2H3 mast cells Cell Signal 14 2002 633 639
    • (2002) Cell Signal , vol.14 , pp. 633-639
    • Jeong, H.J.1    Hong, S.H.2    Lee, D.J.3    Park, J.H.4    Kim, K.S.5    Kim, H.M.6
  • 12
    • 0038434290 scopus 로고    scopus 로고
    • Expression of proinflammatory cytokines via HIF-1alpha and NF-kappaB activation on desferrioxamine-stimulated HMC-1 cells
    • H.J. Jeong, H.S. Chung, B.R. Lee, S.J. Kim, S.J. Yoo, S.H. Hong, and H.M. Kim Expression of proinflammatory cytokines via HIF-1alpha and NF-kappaB activation on desferrioxamine-stimulated HMC-1 cells Biochem. Biophys. Res. Commun. 306 2003 805 811
    • (2003) Biochem. Biophys. Res. Commun. , vol.306 , pp. 805-811
    • Jeong, H.J.1    Chung, H.S.2    Lee, B.R.3    Kim, S.J.4    Yoo, S.J.5    Hong, S.H.6    Kim, H.M.7
  • 14
    • 0038308411 scopus 로고    scopus 로고
    • A cochlear cell line as an in vitro system for drug ototoxicity screening
    • G.M. Kalinec, P. Webster, D.J. Lim, and F. Kalinec A cochlear cell line as an in vitro system for drug ototoxicity screening Audiol. Neurootol. 8 2003 177 189
    • (2003) Audiol. Neurootol. , vol.8 , pp. 177-189
    • Kalinec, G.M.1    Webster, P.2    Lim, D.J.3    Kalinec, F.4
  • 15
    • 0036058185 scopus 로고    scopus 로고
    • Stabilization of hypoxia-inducible factor-1alpha is involved in the hypoxic stimuli-induced expression of vascular endothelial growth factor in osteoblastic cells
    • H.H. Kim, S.E. Lee, W.J. Chung, Y. Choi, K. Kwack, S.W. Kim, M.S. Kim, H. Park, and Z.H. Lee Stabilization of hypoxia-inducible factor-1alpha is involved in the hypoxic stimuli-induced expression of vascular endothelial growth factor in osteoblastic cells Cytokine 17 2002 14 27
    • (2002) Cytokine , vol.17 , pp. 14-27
    • Kim, H.H.1    Lee, S.E.2    Chung, W.J.3    Choi, Y.4    Kwack, K.5    Kim, S.W.6    Kim, M.S.7    Park, H.8    Lee, Z.H.9
  • 16
    • 0031587929 scopus 로고    scopus 로고
    • Novel homologues of CSBP/p38 MAPK: Activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles
    • S. Kumar, P.C. McDonnell, R.J. Gum, A.T. Hand, F.C. Lee, and P.R. Young Novel homologues of CSBP/p38 MAPK: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles Biochem. Biophys. Res. Commun. 235 1997 533 538
    • (1997) Biochem. Biophys. Res. Commun. , vol.235 , pp. 533-538
    • Kumar, S.1    McDonnell, P.C.2    Gum, R.J.3    Hand, A.T.4    Lee, F.C.5    Young, P.R.6
  • 17
    • 0030132745 scopus 로고    scopus 로고
    • Noise-induced cochlear hypoxia is intensity dependent, correlates with hearing loss and precedes reduction of cochlear blood flow
    • K. Lamm, and W. Arnold Noise-induced cochlear hypoxia is intensity dependent, correlates with hearing loss and precedes reduction of cochlear blood flow Audiol. Neurootol. 1 1996 148 160
    • (1996) Audiol. Neurootol. , vol.1 , pp. 148-160
    • Lamm, K.1    Arnold, W.2
  • 18
    • 0030581626 scopus 로고    scopus 로고
    • The primary structure of p38 gamma: A new member of p38 group of MAPKs
    • Z. Li, Y. Jiang, R.J. Ulevitch, and J. Han The primary structure of p38 gamma: a new member of p38 group of MAPKs Biochem. Biophys. Res. Commun. 228 1996 334 340
    • (1996) Biochem. Biophys. Res. Commun. , vol.228 , pp. 334-340
    • Li, Z.1    Jiang, Y.2    Ulevitch, R.J.3    Han, J.4
  • 20
    • 0031892538 scopus 로고    scopus 로고
    • The stress inducer arsenite activates mitogen-activated protein kinases extracellular signal-regulated kinases 1 and 2 via a MAPK kinase 6/p38-dependent pathway
    • S. Ludwig, A. Hoffmeyer, M. Goebeler, K. Kilian, H. Hafner, B. Neufeld, J. Han, and U.R. Rapp The stress inducer arsenite activates mitogen-activated protein kinases extracellular signal-regulated kinases 1 and 2 via a MAPK kinase 6/p38-dependent pathway J. Biol. Chem. 273 1998 1917 1922
    • (1998) J. Biol. Chem. , vol.273 , pp. 1917-1922
    • Ludwig, S.1    Hoffmeyer, A.2    Goebeler, M.3    Kilian, K.4    Hafner, H.5    Neufeld, B.6    Han, J.7    Rapp, U.R.8
  • 22
    • 0035037466 scopus 로고    scopus 로고
    • Immunohistochemical detection of vascular endothelial growth factor (VEGF) and VEGF receptors Flt-1 and KDR/Flk-1 in the cochlea of guinea pigs
    • O. Michel, A. Hess, W. Bloch, A. Schmidt, E. Stennert, and K. Addicks Immunohistochemical detection of vascular endothelial growth factor (VEGF) and VEGF receptors Flt-1 and KDR/Flk-1 in the cochlea of guinea pigs Hear. Res. 155 2001 175 180
    • (2001) Hear. Res. , vol.155 , pp. 175-180
    • Michel, O.1    Hess, A.2    Bloch, W.3    Schmidt, A.4    Stennert, E.5    Addicks, K.6
  • 24
    • 3543129535 scopus 로고    scopus 로고
    • Age-dependent modifications of expression level of VEGF and its receptors in the inner ear
    • P. Picciotti, T. Torsello, I.F. Wolf, G. Paludetti, E. Gaetani, and R. Pola Age-dependent modifications of expression level of VEGF and its receptors in the inner ear Exp. Gerontol. 39 2004 1253 1258
    • (2004) Exp. Gerontol. , vol.39 , pp. 1253-1258
    • Picciotti, P.1    Torsello, T.2    Wolf, I.F.3    Paludetti, G.4    Gaetani, E.5    Pola, R.6
  • 26
    • 0034282388 scopus 로고    scopus 로고
    • Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells
    • D.E. Richard, E. Berra, and J. Pouyssegur Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells J. Biol. Chem. 275 2000 26765 26771
    • (2000) J. Biol. Chem. , vol.275 , pp. 26765-26771
    • Richard, D.E.1    Berra, E.2    Pouyssegur, J.3
  • 27
    • 0035864361 scopus 로고    scopus 로고
    • Accumulation of HIF-1alpha under the influence of nitric oxide
    • K.B. Sandau, J. Fandrey, and B. Brune Accumulation of HIF-1alpha under the influence of nitric oxide Blood 97 2001 1009 1015
    • (2001) Blood , vol.97 , pp. 1009-1015
    • Sandau, K.B.1    Fandrey, J.2    Brune, B.3
  • 28
    • 0031590460 scopus 로고    scopus 로고
    • Hypoxia and hypoxia/reoxygenation activate p65PAK, p38 mitogen-activated protein kinase (MAPK), and stress-activated protein kinase (SAPK) in cultured rat cardiac myocytes
    • Y. Seko, N. Takahashi, K. Tobe, T. Kadowaki, and Y. Yazaki Hypoxia and hypoxia/reoxygenation activate p65PAK, p38 mitogen-activated protein kinase (MAPK), and stress-activated protein kinase (SAPK) in cultured rat cardiac myocytes Biochem. Biophys. Res. Commun. 239 1997 840 844
    • (1997) Biochem. Biophys. Res. Commun. , vol.239 , pp. 840-844
    • Seko, Y.1    Takahashi, N.2    Tobe, K.3    Kadowaki, T.4    Yazaki, Y.5
  • 29
    • 0034901463 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: Oxygen homeostasis and disease pathophysiology
    • G.L. Semenza Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology Trends Mol. Med. 7 2001 345 350
    • (2001) Trends Mol. Med. , vol.7 , pp. 345-350
    • Semenza, G.L.1
  • 30
    • 0028068606 scopus 로고
    • Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
    • G.L. Semenza, P.H. Roth, H.M. Fang, and G.L. Wang Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1 J. Biol. Chem. 269 1994 23757 23763
    • (1994) J. Biol. Chem. , vol.269 , pp. 23757-23763
    • Semenza, G.L.1    Roth, P.H.2    Fang, H.M.3    Wang, G.L.4
  • 33
    • 0031569363 scopus 로고    scopus 로고
    • Hyperosmotic stress as a stimulant for proinflammatory cytokine production
    • L. Shapiro, and C.A. Dinarello Hyperosmotic stress as a stimulant for proinflammatory cytokine production Exp. Cell Res. 231 1997 354 362
    • (1997) Exp. Cell Res. , vol.231 , pp. 354-362
    • Shapiro, L.1    Dinarello, C.A.2
  • 34
    • 0036228789 scopus 로고    scopus 로고
    • Hypoxic induction of HIF-1alpha and VEGF expression in head and neck squamous cell carcinoma lines is mediated by stress activated protein kinases
    • B. Shemirani, and D.L. Crowe Hypoxic induction of HIF-1alpha and VEGF expression in head and neck squamous cell carcinoma lines is mediated by stress activated protein kinases Oral Oncol. 38 2002 251 257
    • (2002) Oral Oncol. , vol.38 , pp. 251-257
    • Shemirani, B.1    Crowe, D.L.2
  • 35
    • 0034282553 scopus 로고    scopus 로고
    • The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha
    • A. Sodhi, S. Montaner, V. Patel, M. Zohar, C. Bais, E.A. Mesri, and J.S. Gutkind The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha Cancer Res. 60 2000 4873 4880
    • (2000) Cancer Res. , vol.60 , pp. 4873-4880
    • Sodhi, A.1    Montaner, S.2    Patel, V.3    Zohar, M.4    Bais, C.5    Mesri, E.A.6    Gutkind, J.S.7
  • 36
    • 0037070223 scopus 로고    scopus 로고
    • Normoxic induction of the hypoxia-inducible factor 1alpha by insulin and interleukin-1 beta involves the phosphatidylinositol 3-kinase pathway
    • D.P. Stiehl, W. Jelkmann, R.H. Wenger, and T. Hellwig-Burgel Normoxic induction of the hypoxia-inducible factor 1alpha by insulin and interleukin-1 beta involves the phosphatidylinositol 3-kinase pathway FEBS Lett. 512 2002 157 162
    • (2002) FEBS Lett. , vol.512 , pp. 157-162
    • Stiehl, D.P.1    Jelkmann, W.2    Wenger, R.H.3    Hellwig-Burgel, T.4
  • 37
    • 0034663561 scopus 로고    scopus 로고
    • Interleukin 1 induces hypoxia-inducible factor 1 in human gingival and synovial fibroblasts
    • R.D. Thornton, P. Lane, R.C. Borghaei, E.A. Pease, J. Caro, and E. Mochan Interleukin 1 induces hypoxia-inducible factor 1 in human gingival and synovial fibroblasts Biochem. J. 350 2000 307 312
    • (2000) Biochem. J. , vol.350 , pp. 307-312
    • Thornton, R.D.1    Lane, P.2    Borghaei, R.C.3    Pease, E.A.4    Caro, J.5    Mochan, E.6
  • 38
    • 0027427588 scopus 로고
    • Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia
    • G.L. Wang, and G.L. Semenza Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia J. Biol. Chem. 268 1993 21513 21518
    • (1993) J. Biol. Chem. , vol.268 , pp. 21513-21518
    • Wang, G.L.1    Semenza, G.L.2
  • 39
    • 0027136260 scopus 로고
    • Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: Implications for models of hypoxia signal transduction
    • G.L. Wang, and G.L. Semenza Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction Blood 82 1993 3610 3615
    • (1993) Blood , vol.82 , pp. 3610-3615
    • Wang, G.L.1    Semenza, G.L.2
  • 40
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxia-inducible factor 1
    • G.L. Wang, and G.L. Semenza Purification and characterization of hypoxia-inducible factor 1 J. Biol. Chem. 270 1995 1230 1237
    • (1995) J. Biol. Chem. , vol.270 , pp. 1230-1237
    • Wang, G.L.1    Semenza, G.L.2
  • 42
    • 0034107952 scopus 로고    scopus 로고
    • Mammalian oxygen sensing, signalling and gene regulation
    • R.H.J. Wenger Mammalian oxygen sensing, signalling and gene regulation J. Exp. Biol. 203 2000 1253 1263
    • (2000) J. Exp. Biol. , vol.203 , pp. 1253-1263
    • Wenger, R.H.J.1
  • 43
    • 0035918213 scopus 로고    scopus 로고
    • Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, and p300/CBP
    • K. Yamashita, D.J. Discher, J. Hu, N.H. Bishopric, and K.A. Webster Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, and p300/CBP J. Biol. Chem. 276 2001 12645 12653
    • (2001) J. Biol. Chem. , vol.276 , pp. 12645-12653
    • Yamashita, K.1    Discher, D.J.2    Hu, J.3    Bishopric, N.H.4    Webster, K.A.5
  • 44
    • 0034654174 scopus 로고    scopus 로고
    • Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
    • H. Zhong, K. Chiles, D. Feldser, E. Laughner, C. Hanrahan, M.M. Georgescu, J.W. Simons, and G.L. Semenza Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics Cancer Res. 60 2000 1541 1545
    • (2000) Cancer Res. , vol.60 , pp. 1541-1545
    • Zhong, H.1    Chiles, K.2    Feldser, D.3    Laughner, E.4    Hanrahan, C.5    Georgescu, M.M.6    Simons, J.W.7    Semenza, G.L.8
  • 45
    • 0034816245 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha and 1beta proteins share common signaling pathways in human prostate cancer cells
    • H. Zhong, C. Hanrahan, H. van der Poel, and J.W. Simons Hypoxia-inducible factor 1alpha and 1beta proteins share common signaling pathways in human prostate cancer cells Biochem. Biophys. Res. Commun. 284 2001 352 356
    • (2001) Biochem. Biophys. Res. Commun. , vol.284 , pp. 352-356
    • Zhong, H.1    Hanrahan, C.2    Van Der Poel, H.3    Simons, J.W.4
  • 46
    • 1842691021 scopus 로고    scopus 로고
    • PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation
    • J. Zhou, T. Schmid, R. Frank, and B. Brune PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation J. Biol. Chem. 279 2004 13506 13513
    • (2004) J. Biol. Chem. , vol.279 , pp. 13506-13513
    • Zhou, J.1    Schmid, T.2    Frank, R.3    Brune, B.4
  • 47
    • 0032519736 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase activation is required for human neutrophil function triggered by TNF-alpha or FMLP stimulation
    • Y.L. Zu, J. Qi, A. Gilchrist, G.A. Fernandez, D. Vazquez-Abad, D.L. Kreutzer, C.K. Huang, and R.I. Sha'afi p38 mitogen-activated protein kinase activation is required for human neutrophil function triggered by TNF-alpha or FMLP stimulation J. Immunol. 160 1998 1982 1989
    • (1998) J. Immunol. , vol.160 , pp. 1982-1989
    • Zu, Y.L.1    Qi, J.2    Gilchrist, A.3    Fernandez, G.A.4    Vazquez-Abad, D.5    Kreutzer, D.L.6    Huang, C.K.7    Sha'Afi, R.I.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.