A new structural motif for μ-opioid antagonists

Journal of Medicinal Chemistry

Volumn 48, Issue 10, 2005, Pages 3644-3648

  Van Den Eynde, Isabelle ^a   Laus, Georges ^a   Schiller, Peter W ^b   Kosson, Piotr ^c   Chung, Nga N ^b   Lipkowski, Andrzej W ^c   Tourwé, Dirk ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^c MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

2',6' DIMETHYLTYROSINE; 3 [4 (2 PHENYLACETYLAMINO) 1,2,4,5 TETRAHYDRO 2 BENZAZEPINE 3 ONE 2 YL] 2 AMINO 1(2,6 DIMETHYL 4 HYDROXYPHENYL)PROPANE; 4 AMINO 1,2,3,4,5 TETRAHYDRO 2 BENZAZEPINE 3 ONE; ALANINE DERIVATIVE; BENZAZEPINE DERIVATIVE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR ANTAGONIST; O AMINOMETHYLPHENYLALANINE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; MALE; NONHUMAN; PHARMACOPHORE; RAT; STEREOCHEMISTRY; STEREOISOMERISM; STRUCTURE ANALYSIS;

ANIMALS; BENZAZEPINES; ELECTRIC STIMULATION; GUINEA PIGS; ILEUM; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PROPANE; RADIOLIGAND ASSAY; RECEPTORS, OPIOID, MU; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 18644373178     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0491795     Document Type: Article

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