Structure-activity relationships of 2-substituted 5,7-Diarylcyclopenteno[1,2-b]pyridine-6-carboxylic acids as a novel class of endothelin receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 21, 2002, Pages 3041-3045

  Niiyama, Kenji ^a   Takahashi, Hirobumi ^a   Nagase, Toshio ^a   Kojima, Hisaki ^a   Amano, Yuka ^a   Katsuki, Kasumi ^a   Yamakawa, Takeru ^a   Ozaki, Satoshi ^a   Ihara, Masaki ^a   Yano, Mitsuo ^a   Fukuroda, Takahiro ^a   Nishikibe, Masaru ^a   Ishikawa, Kiyofumi ^a  

^a BANYU PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL GROUP; AMINO ACID DERIVATIVE; CYCLOPENTENO[1,2]PYRIDINE 6 CARBOXYLIC ACID; CYCLOPENTENONE DERIVATIVE; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DERIVATIZATION; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

BINDING, COMPETITIVE; CYCLOPENTANES; HUMANS; INDICATORS AND REAGENTS; PYRIDINES; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 18644371317     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00663-7     Document Type: Article

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