Deficits in gray matter volume are present in schizophrenia but not bipolar disorder

Schizophrenia Research

Volumn 26, Issue 2-3, 1997, Pages 85-92

  Zipursky, Robert B ^a,c   Seeman, Mary V ^a,c   Bury, Alison ^a   Langevin, Ronald ^c   Wortzman, George ^b,c   Katz, Randy ^c  

^a CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Bipolar; Gray matter; Magnetic resonance imaging; Schizophrenia; Ventricle

Indexed keywords

ADULT; ARTICLE; BRAIN SIZE; CONTROLLED STUDY; FEMALE; GRAY MATTER; HUMAN; MAJOR CLINICAL STUDY; MALE; MANIC DEPRESSIVE PSYCHOSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SCHIZOPHRENIA; WHITE MATTER;

ADULT; BIPOLAR DISORDER; CEREBRAL CORTEX; CEREBRAL VENTRICLES; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY;

EID: 0030791835     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-9964(97)00042-X     Document Type: Article

References (40)

1. Akbarian S., Bunney W.E.J., Potkin S.G.et al. Altered distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase cells in frontal lobe of schizophrenics implies disturbances of cortical development. Archives of General Psychiatry. 50:1993;169-177.
2. Altshuler L.L., Conrad A., Hauser P.et al. Reduction of temporal lobe volume in bipolar disorder: a preliminary report of magnetic resonance imaging. Archives of General Psychiatry. 48:1991;482-483.
3. Altshuler L.L., Curran J.G., Hauser P., Mintz J., Denicoff K., Post R. T2 hyperintensities in bipolar disorder: magnetic resonance imaging comparison and literature meta-analysis. American Journal of Psychiatry. 152:1995;1139-1144.
4. American Psychiatric Association, 1987. Diagnostic and Statistical Manual of Mental Disorder (DSM-III-R). American Psychiatric Association, Washington.
5. Aylward E.H., Roberts-Twille J.V., Barta P.E.et al. Basal ganglial volumes and white matter hyperintensities in patients with bipolar disorder. American Journal of Psychiatry. 151:1994;687-693.
6. Bogerts B., Ashtari M., Degreet G., Alvir J.M., Bilder R.M., Lieberman J.A. Reduced temporal limbic structure volumes on magnetic resonance images in first episode schizophrenia. Psychiatry Research: Neuroimaging. 35:1990;1-13.
7. Bogerts B., Meertz E., Schonfeldt-Bausch R. Basal ganglia and limbic system pathology in schizophrenia. Archives of General Psychiatry. 42:1985;784-791.
8. Brown R., Colter N., Corsellis N.et al. Postmortem evidence of structural brain changes in schizophrenia: differences in brain weight, temporal horn area and parahippocampal gyrus compared with affective disorder. Archives of General Psychiatry. 43:1986;36-42.
9. Cleghorn J.M., Zipursky R.B., List S.J. Structural and functional brain imaging in schizophrenia. Journal of Psychiatry and Neuroscience. 16:1991;53-74.
10. Colombo C., Abbruzzese M., Livian S.et al. Memory functions and temporal-limbic morphology in schizophrenia. Psychiatry Research: Neuroimaging. 50:1993;45-56.
11. DeLisi L.E., Hoff A.L., Schwartz J.E.et al. Brain morphology in first-episode schizophrenic-like psychotic patients: a quantitative magnetic resonance imaging study. Biological Psychiatry. 29:1991;159-175.
12. Dupont R.M., Jernigan T.L., Butters N.et al. Subcortical abnormalities detected in bipolar affective disorder using magnetic resonance imaging: clinical and neuropsychological significance. Archives of General Psychiatry. 47:1990;55-59.
13. Dupont R.M., Jernigan T.L., Gillin J.C., Butters N., Delis D.C., Hesselink J.R. Subcortical signal hyperintensities in bipolar patients detected with MRI. Psychiatry Research. 21:1987;357-358.
14. Dupont R.M., Jernigan T.L., Heindel W.et al. Magnetic resonance imaging and mood disorders: localization of white matter and other subcortical abnormalities. Archives of General Psychiatry. 52:1995;747-755.
15. Elkis H., Friedman L., Wise A., Meltzer H.Y. Meta-analyses of studies of ventricular enlargement and cortical sulcal prominence in mood disorders; comparison with controls or patients with schizophrenia. Archives of General Psychiatry. 52:1995;735-746.
16. Endicott J., Spitzer R.L. A diagnostic interview: The Schedule for Affective Disorders and Schizophrenia. Archives of General Psychiatry. 35:1978;837-844.
17. Falkai P., Bogerts B., Rozumek M. Limbic pathology in schizophrenia: the entorhinal region-A morphometric study. Biological Psychiatry. 24:1988;515-521.
18. Figiel G.S., Krishnan K.R.R., Rao V.P.et al. Subcortical hyperintensities on brain magnetic resonance imaging: a comparison of normal and bipolar subjects. Journal of Neuropsychiatry and Clinical Neurosciences. 3:1991;18-22.
19. Gavin D.R., Ross H.E., Skinner H.A. Diagnostic validity of the Drug Abuse Screening Test in the assessment of DSM-III drug disorders. British Journal of Addiction. 84:1989;301-307.
20. Harvey I., Persaud R., Ron M.A., Baker G., Murray R.M. Volumetric MRI measurements in bipolars compared with schizophrenics and healthy controls. Psychological Medicine. 24:1994;689-699.
21. Harvey I., Ron M., Duboulay G., Murray R., Lewis S. White matter abnormalities on magnetic resonance imaging in bipolar patients. Archives of General Psychiatry. 47:1990;1172-1173.
22. Harvey I., Ron M.A., du Bouley G., Wicks D., Lewis S.W., Murray R.M. Reduction of cortical volume in schizophrenia on magnetic resonance imaging. Psychological Medicine. 23:1993;591-604.
23. Kelsoe J.R., Cadet J.L., Pickar D., Weinberger D.R. Quantitative neuroanatomy in schizophrenia. Archives of General Psychiatry. 45:1988;533-541.
24. Kovelman J.A., Scheibel A.B. A neurohistological correlate of schizophrenia. Biological Psychiatry. 19:1984;1601-1621.
25. Lahey M.A., Downey R.G., Saal F.E. Intraclass correlations: there's more than meets the eye. Psychological Bulletin. 91:1983;586-595.
26. Lim K.O., Harris D., Beal M.et al. Gray matter deficits in young onset schizophrenia are independent of age of onset. Biological Psychiatry. 40:1996;4-13.
27. Lim K.O., Pfefferbaum A. Segmentation of MR brain images into cerebrospinal fluid spaces, white and gray matter. Journal of Computer Assisted Tomography. 13:1989;588-593.
28. Lim K.O., Sullivan E.V., Zipursky R.B., Pfefferbaum A. Cortical gray matter volume deficits in schizophrenia: a replication. Schizophrenia Research. 20:1996;157-164.
29. Pfefferbaum A., Lim K.O., Rosenbloom M., Zipursky R.B. Brain magnetic resonance imaging: approaches for investigating schizophrenia. Schizophrenia Bulletin. 16:1990;453-476.
30. Raz S., Raz N. Structural brain abnormalities in the major psychoses: a quantitative review of the evidence from computerized imaging. Psychological Bulletin. 108:1990;93-108.
31. Reiss, A.L., Hennessey, J., Subramanium, B., Rubin, M., Beach, L., 1995. Brain Image. Kennedy Krieger Institute Neuroimaging Research Center, Baltimore.
32. Schlaepfer T.E., Harris G.J., Tien A.Y.et al. Decreased regional cortical gray matter volume in schizophrenia. American Journal of Psychiatry. 151:1994;842-848.
33. Selemon L.D., Rajkowska G., Goldman-Rakic P.S. Abnormally high neuronal density in the schizophrenic cortex: a morphometric analysis of prefrontal area 9 and occipital area 8 and occipital area 17. Archives of General Psychiatry. 52:1995;805-818.
34. Shenton M.E., Kikinis R., Jolesz F.A.et al. Abnormalities of the left temporal lobe and thought disorder in schizophrenia. The New England Journal of Medicine. 327:1992;604-612.
35. Skinner H.A., Sheu W.J. Reliability of alcohol use indices: the lifetime drinking history and the MAST. Journal of Studies on Alcohol. 43:1982;1157-1170.
36. Suddath R., Casanova M.F., Goldberg T.E., Daniel D.G., Kelsoe J.R., Weinberger D.R. Temporal lobe pathology in schizophrenia: a quantitative magnetic resonance imaging study. American Journal of Psychiatry. 146:1989;464-472.
37. Suddath R.L., Christison G.W., Fuller Torrey E., Casanova M.F., Weinberg D.R. Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia. New England Journal of Medicine. 322:1990;789-794.
38. Swayze V.W., Andreasen N.C., Alliger R.J., Ehrhardt J.C., Yuh W.T.C. Structural brain abnormalities in bipolar affective disorder: ventricular enlargement and focal signal hyperintensities. Archives of General Psychiatry. 47:1990;1054-1059.
39. Zipursky R.B., Lim K.O., Sullivan E.V., Brown B.W., Pfefferbaum A. Widespread cerebral gray matter volume deficits in schizophrenia. Archives of General Psychiatry. 49:1992;195-205.
40. Zipursky R.B., Marsh L., Lim K.O.et al. Volumetric MRI assessment of temporal lobe structures in schizophrenia. Biological Psychiatry. 35:1994;501-516.