Mitochondrial dysfunction in Friedreich's ataxia: From pathogenesis to treatment perspectives

Free Radical Research

Volumn 36, Issue 4, 2002, Pages 461-466

  Lodi, R ^a   Rajagopalan, B ^b   Bradley, J L ^c   Taylor, D J ^b   Crilley, J G ^b   Hart, P E ^c   Blamire, A M ^b   Manners, D ^b   Styles, P ^b   Schapira, A H V ^a   Cooper, J M ^c  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Cardiomyopathy; Friedreich's ataxia; Genetics; Iron metabolism; Mitochondria; Oxidative stress

Indexed keywords

ADENINE; ALPHA TOCOPHEROL; ANTIOXIDANT; FRATAXIN; GENE PRODUCT; GUANINE; IDEBENONE; IRON; UBIDECARENONE;

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CHROMOSOME 9Q; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISEASE ASSOCIATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENERGY METABOLISM; FRIEDREICH ATAXIA; GENE LOCATION; HEART MUSCLE; HUMAN; IN VIVO STUDY; INHERITANCE; METHODOLOGY; OXIDATIVE STRESS; PATHOGENESIS; PILOT STUDY; POINT MUTATION; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY CHAIN; SKELETAL MUSCLE; TRINUCLEOTIDE REPEAT;

ANTIOXIDANTS; CARRIER PROTEINS; CYTOPROTECTION; FRIEDREICH ATAXIA; HUMANS; IRON-BINDING PROTEINS; MITOCHONDRIA, MUSCLE; MUSCLE, SKELETAL; OXIDATIVE STRESS; POINT MUTATION; TRINUCLEOTIDE REPEATS; UBIQUINONE; VITAMIN E;

ATAXIA;

EID: 18644366906     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/10715760290021324     Document Type: Article

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