Deletion of the glutamate carboxypeptidase II gene in mice reveals a second enzyme activity that hydrolyzes N-acetylaspartylglutamate

Journal of Neurochemistry

Volumn 83, Issue 1, 2002, Pages 20-29

  Bacich, Dean J ^a   Ramadan, Epolia ^b   O'Keefe, Denise S ^a   Bukhari, Noreen ^b   Wegorzewska, Iga ^b   Ojeifo, Olumide ^b   Olszewski, Rafal ^b   Wrenn, Craige C ^c   Bzdega, Tomasz ^b   Wroblewska, Barbara ^b   Heston, Warren D W ^a   Neale, Joseph H ^b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b GEORGETOWN UNIVERSITY   (United States)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Glutamate carboxypeptidase II metabotropic glutamate receptor; N acetyl aspartylglutamate peptidase (NAAG peptidase); N acetylaspartylglutamate (NAAG)

Indexed keywords

COPPER; GAMMA GLUTAMYL HYDROLASE; GLUTAMATE CARBOXYPEPTIDASE II; MAGNESIUM; MESSENGER RNA; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 3; N ACETYLASPARTYLGLUTAMIC ACID; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CONTROLLED STUDY; ENZYME ACTIVITY; EXON; GENE DELETION; GENE DISRUPTION; HOT PLATE TEST; HYDROLYSIS; IC 50; INTRON; KIDNEY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; NORTHERN BLOTTING; OPEN FIELD BEHAVIOR; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD; TAIL FLICK TEST; WESTERN BLOTTING;

ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; BRAIN; BRAIN CHEMISTRY; CARBOXYPEPTIDASES; CELL MEMBRANE; CHO CELLS; CRICETINAE; DIPEPTIDES; ENZYME ACTIVATION; GENE TARGETING; GENOTYPE; GLUTAMATE CARBOXYPEPTIDASE II; HYDROLYSIS; KIDNEY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, METABOTROPIC GLUTAMATE; RNA, MESSENGER; SPINAL CORD; SYNAPSES;

ANIMALIA;

EID: 18544378307     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.01117.x     Document Type: Article

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