메뉴 건너뛰기




Volumn 5, Issue 1, 2005, Pages 75-90

Diminished myofibril organization in mutant axolotl hearts transfected with site-directed mutants of sarcomeric tropomyosins

Author keywords

Gene transfer; Partial disarray; Sarcomere; Site directed mutagenesis; Tropomyosin

Indexed keywords

ASPARTIC ACID; GLUTAMIC ACID; GLUTAMINE; HYBRID PROTEIN; LIPOSOME; LYSINE; TROPOMYOSIN; TROPOMYOSIN 4ALPHA; UNCLASSIFIED DRUG;

EID: 18544369423     PISSN: 15307905     EISSN: None     Source Type: Journal    
DOI: 10.1385/ct:5:1:075     Document Type: Article
Times cited : (4)

References (36)
  • 1
    • 0020144137 scopus 로고
    • Quantitation of tropomyosin by radioimmunoassay in developing hearts of cardiac mutant axolotls, Ambystoma mexicanum
    • Moore, P.B. and Lemanski, L.F. (1982). Quantitation of tropomyosin by radioimmunoassay in developing hearts of cardiac mutant axolotls, Ambystoma mexicanum. J. Muscle Res. Cell Motil. 3:161-167.
    • (1982) J. Muscle Res. Cell Motil. , vol.3 , pp. 161-167
    • Moore, P.B.1    Lemanski, L.F.2
  • 2
    • 0024698371 scopus 로고
    • Analysis of actin and tropomyosin in hearts of cardiac mutant axolotls by two-dimensional gel electrophoresis, western blots, and immunofluorescent microscopy
    • Starr, C., Diaz, J.G., and Lemanski, L.F. (1989). Analysis of actin and tropomyosin in hearts of cardiac mutant axolotls by two-dimensional gel electrophoresis, western blots, and immunofluorescent microscopy. J. Morphol. 210: 1-10.
    • (1989) J. Morphol. , vol.210 , pp. 1-10
    • Starr, C.1    Diaz, J.G.2    Lemanski, L.F.3
  • 4
    • 0033134015 scopus 로고    scopus 로고
    • The cardiac mutant Mexican axolotl is a unique animal model for evaluation of cardiac myofibrillogenesis
    • Zajdel, R.W., Dube, D.K., and Lemanski, L.F. (1999). The cardiac mutant Mexican axolotl is a unique animal model for evaluation of cardiac myofibrillogenesis. Exp. Cell Res. 248:557-566.
    • (1999) Exp. Cell Res. , vol.248 , pp. 557-566
    • Zajdel, R.W.1    Dube, D.K.2    Lemanski, L.F.3
  • 5
    • 0024516197 scopus 로고
    • Disruption of the single tro-pomyosin gene in yeast results in the disappearance of actin cables from the cytoskeleton
    • Liu, H. and Bretscher, A. (1989). Disruption of the single tro-pomyosin gene in yeast results in the disappearance of actin cables from the cytoskeleton. Cell 57:233-242.
    • (1989) Cell , vol.57 , pp. 233-242
    • Liu, H.1    Bretscher, A.2
  • 7
    • 0031908697 scopus 로고    scopus 로고
    • Molecular and physiological effects of alpha-tropomyosin ablation in the mouse
    • Rethinasamy, P., Muthuchamy, M., Hewett, T., Boivin, G., Wolska, B.M., Evans, C., et al. (1998). Molecular and physiological effects of alpha-tropomyosin ablation in the mouse. Circ. Res. 82:116-123.
    • (1998) Circ. Res. , vol.82 , pp. 116-123
    • Rethinasamy, P.1    Muthuchamy, M.2    Hewett, T.3    Boivin, G.4    Wolska, B.M.5    Evans, C.6
  • 9
    • 0032526155 scopus 로고    scopus 로고
    • A truncated troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy
    • Tardiff, J.C., Factor, S.M., Tompkins, B.D., Hewett, T.E., Palmer, B.M., Moore, R.L., et al. (1998). A truncated troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy. J. Clin. Invest. 101:2800-2811.
    • (1998) J. Clin. Invest. , vol.101 , pp. 2800-2811
    • Tardiff, J.C.1    Factor, S.M.2    Tompkins, B.D.3    Hewett, T.E.4    Palmer, B.M.5    Moore, R.L.6
  • 10
    • 0032943836 scopus 로고    scopus 로고
    • Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the α-cardiac myosin heavy chain gene
    • Fatkin, D., Christe, M.E., Aristizabal, O., McConnell, B.K., Srinivasan, S., Schoen, F.J., et al. (1999). Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the α-cardiac myosin heavy chain gene. J. Clin. Invest. 103:147-153.
    • (1999) J. Clin. Invest. , vol.103 , pp. 147-153
    • Fatkin, D.1    Christe, M.E.2    Aristizabal, O.3    McConnell, B.K.4    Srinivasan, S.5    Schoen, F.J.6
  • 11
    • 0029164976 scopus 로고
    • Novel missense mutation in α-tropomyosin gene found in Japanese patients with hypertrophic cardiomyopathy
    • Nakajima-Taniguchi, C., Matsui, H., Nagata, S., Kishimoto, T., and Yamauchi-Takihara, K. (1995). Novel missense mutation in α-tropomyosin gene found in Japanese patients with hypertrophic cardiomyopathy. J. Mol. Cell. Cardiol. 27:2053-2058.
    • (1995) J. Mol. Cell. Cardiol. , vol.27 , pp. 2053-2058
    • Nakajima-Taniguchi, C.1    Matsui, H.2    Nagata, S.3    Kishimoto, T.4    Yamauchi-Takihara, K.5
  • 13
    • 0035830394 scopus 로고    scopus 로고
    • Hypertrophic cardiomyopathy caused by a novel alpha-tropomyosin mutation (V95A) is associated with mild cardiac phenotype, abnormal calcium binding to troponin, abnormal myosin cycling, and poor prognosis
    • Karibe, A., Tobacman, L.S., Strand, J., Butters, C., Back, N., Bachinski, L.L., et al. (2001). Hypertrophic cardiomyopathy caused by a novel alpha-tropomyosin mutation (V95A) is associated with mild cardiac phenotype, abnormal calcium binding to troponin, abnormal myosin cycling, and poor prognosis. Circulation 103(1):65-71.
    • (2001) Circulation , vol.103 , Issue.1 , pp. 65-71
    • Karibe, A.1    Tobacman, L.S.2    Strand, J.3    Butters, C.4    Back, N.5    Bachinski, L.L.6
  • 14
    • 0031042881 scopus 로고    scopus 로고
    • Clinical features of hypertrophic cardiomyopathy caused by mutation of a "hot spot" in the α-tropomyosin gene
    • Coviello, D.A., Maron, B.J., Spirito, P., Watkins, H., Vosberg, H.P., Thierfelder, L., et al. (1997). Clinical features of hypertrophic cardiomyopathy caused by mutation of a "hot spot" in the α-tropomyosin gene. J. Am. Coll. Cardiol. 29:635-640.
    • (1997) J. Am. Coll. Cardiol. , vol.29 , pp. 635-640
    • Coviello, D.A.1    Maron, B.J.2    Spirito, P.3    Watkins, H.4    Vosberg, H.P.5    Thierfelder, L.6
  • 15
    • 0344878860 scopus 로고    scopus 로고
    • The cardiac β-myosin heavy chain gene is not the predominant gene for hypertrophic cardiomyopathy in the Finnish population
    • Jaaskelainen, P., Sorantaa, M., Miettinen, R., Saarinen, L., Pihlajamaki, J., Slivennoinen, K., et al. (1998). The cardiac β-myosin heavy chain gene is not the predominant gene for hypertrophic cardiomyopathy in the Finnish population. J. Am. Coll. Cardiol. 32:1709-1716.
    • (1998) J. Am. Coll. Cardiol. , vol.32 , pp. 1709-1716
    • Jaaskelainen, P.1    Sorantaa, M.2    Miettinen, R.3    Saarinen, L.4    Pihlajamaki, J.5    Slivennoinen, K.6
  • 17
    • 0028178083 scopus 로고
    • α-Tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: A disease of the sarcomere
    • Thierfelder, L., Watkins, H., MacRae, C., Lamas, R., McKenna, W., Vosberg, H.P., et al. (1994). α-Tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere. Cell 77:701-712.
    • (1994) Cell , vol.77 , pp. 701-712
    • Thierfelder, L.1    Watkins, H.2    MacRae, C.3    Lamas, R.4    McKenna, W.5    Vosberg, H.P.6
  • 18
    • 0034710851 scopus 로고    scopus 로고
    • Novel mutation inthe α-tropomyosin gene and transition from hypertrophic to hypercontractile dilated cardiomyopathy
    • Regitz-Zagrosek, V., Erdmann, J., Wellenhofer, E., Raible, J., and Fleck, E. (2000). Novel mutation inthe α-tropomyosin gene and transition from hypertrophic to hypercontractile dilated cardiomyopathy. Circulation 102:E112-E116.
    • (2000) Circulation , vol.102
    • Regitz-Zagrosek, V.1    Erdmann, J.2    Wellenhofer, E.3    Raible, J.4    Fleck, E.5
  • 19
    • 0023071735 scopus 로고
    • Structural aspects of troponin-tropomyosin regulation of skeletal muscle contraction
    • Zot, A.S. and Potter, J.D. (1987). Structural aspects of troponin-tropomyosin regulation of skeletal muscle contraction. Ann. Rev. Biophys. Biophys. Chem. 16:535-559.
    • (1987) Ann. Rev. Biophys. Biophys. Chem. , vol.16 , pp. 535-559
    • Zot, A.S.1    Potter, J.D.2
  • 20
    • 0030933128 scopus 로고    scopus 로고
    • Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function
    • Golitsina, N., An, Y., Greenfield, N.J., Thierfelder, L., Iizuka, K., Seidman, J.G., et al. (1997). Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function. Biochemistry 36:4637-4642.
    • (1997) Biochemistry , vol.36 , pp. 4637-4642
    • Golitsina, N.1    An, Y.2    Greenfield, N.J.3    Thierfelder, L.4    Iizuka, K.5    Seidman, J.G.6
  • 21
    • 0031051456 scopus 로고    scopus 로고
    • Differential expression of a novel isoform of alpha-tropomyosin in cardiac and skeletal muscle of the Mexican axolotl (Amby stoma mexicanum)
    • Luque, E.A., Spinner, B.J., Dube, S., Dube, D.K., and Lemanski, L.F. (1997). Differential expression of a novel isoform of alpha-tropomyosin in cardiac and skeletal muscle of the Mexican axolotl (Amby stoma mexicanum). Gene 185:175-185.
    • (1997) Gene , vol.185 , pp. 175-185
    • Luque, E.A.1    Spinner, B.J.2    Dube, S.3    Dube, D.K.4    Lemanski, L.F.5
  • 22
    • 18544381681 scopus 로고    scopus 로고
    • Cardiac myofibril formation is not affected by modification of both N & C-termini of sarcomeric tropomyosin
    • Narshi, A., Denz, C.R., Nakatsugawa, M., Zajdel, R.W., Dube, S., Poiesz, B.J., and Dube, D.K. (2005). Cardiac myofibril formation is not affected by modification of both N & C-termini of sarcomeric tropomyosin. Cardiovas. Toxicol. 5:1-8.
    • (2005) Cardiovas. Toxicol. , vol.5 , pp. 1-8
    • Narshi, A.1    Denz, C.R.2    Nakatsugawa, M.3    Zajdel, R.W.4    Dube, S.5    Poiesz, B.J.6    Dube, D.K.7
  • 23
    • 0038360799 scopus 로고    scopus 로고
    • Identification, characterization, and expression of a novel α-tropomyosin isoform in cardiac tissues in developing chicken
    • Zajdel, R.W., Denz, C.R., Lee, S., Dube, S., Ehler, E., E. Perriard, E., et al. (2003). Identification, characterization, and expression of a novel α-tropomyosin isoform in cardiac tissues in developing chicken. J. Cell Biochem. 89:427-439.
    • (2003) J. Cell Biochem. , vol.89 , pp. 427-439
    • Zajdel, R.W.1    Denz, C.R.2    Lee, S.3    Dube, S.4    Ehler, E.5    Perriard, E.6
  • 24
    • 0025057161 scopus 로고
    • Generation of skeletal, smooth, and low molecular weight non-muscle tropomyosin isoforms for the chicken tropomyosin 1 gene
    • Forry-Schaudies, S., Maihle, N.J., and Hughes, S.H. (1990). Generation of skeletal, smooth, and low molecular weight non-muscle tropomyosin isoforms for the chicken tropomyosin 1 gene. J. Mol. Biol. 211:321-330.
    • (1990) J. Mol. Biol. , vol.211 , pp. 321-330
    • Forry-Schaudies, S.1    Maihle, N.J.2    Hughes, S.H.3
  • 25
    • 0028953381 scopus 로고
    • The Xenopus laevis TM-4 gene encodes non-muscle and cardiac tropomyosin isoforms through alternative splicing
    • Hardy, S., Theze, N., Lepetit, M., Allo, M., and Thiebaud, P. (1995). The Xenopus laevis TM-4 gene encodes non-muscle and cardiac tropomyosin isoforms through alternative splicing. Gene 156:265-270.
    • (1995) Gene , vol.156 , pp. 265-270
    • Hardy, S.1    Theze, N.2    Lepetit, M.3    Allo, M.4    Thiebaud, P.5
  • 26
    • 0032751723 scopus 로고    scopus 로고
    • Direct convergent hypersensitivity of calcium-activated force generation produced by hypertrophic cardiomyopathy mutant α-tropomyosins in adult cardiac myocytes
    • Michele, D.E., Albayya, F.P., and Metzger, J.M. (1999). Direct convergent hypersensitivity of calcium-activated force generation produced by hypertrophic cardiomyopathy mutant α-tropomyosins in adult cardiac myocytes. Nature Med. 5:1413-1417.
    • (1999) Nature Med. , vol.5 , pp. 1413-1417
    • Michele, D.E.1    Albayya, F.P.2    Metzger, J.M.3
  • 27
    • 0029559447 scopus 로고
    • Molecular and physiological effects of overexpressing striated muscle beta-tropomyosin in the adult murine heart
    • Muthuchamy, M., Grupp, I.L., Grupp, G., O'Toole, B.A., Kier, A.B., Boivin, G.P., et al. (1995). Molecular and physiological effects of overexpressing striated muscle beta-tropomyosin in the adult murine heart. J. Biol. Chem. 270:30593-30603.
    • (1995) J. Biol. Chem. , vol.270 , pp. 30593-30603
    • Muthuchamy, M.1    Grupp, I.L.2    Grupp, G.3    O'Toole, B.A.4    Kier, A.B.5    Boivin, G.P.6
  • 28
    • 0026342911 scopus 로고
    • Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice
    • Subramanian, A., Jones, W.K., Gillick, J., Wert, S., Neumann, J., Robbins, J. (1991). Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice. J. Biol. Chem. 266:24613-24620.
    • (1991) J. Biol. Chem. , vol.266 , pp. 24613-24620
    • Subramanian, A.1    Jones, W.K.2    Gillick, J.3    Wert, S.4    Neumann, J.5    Robbins, J.6
  • 29
    • 0033538612 scopus 로고    scopus 로고
    • Mouse model of a familial hypertrophic cardiomyopathy mutation in α-tropomyosin manifests cardiac dysfunction
    • Muthuchamy, M., Pieples, K., Rethinasamy, P., Hoit, B., Grupp, I., Boivin, G.P., et al. (1999). Mouse model of a familial hypertrophic cardiomyopathy mutation in α-tropomyosin manifests cardiac dysfunction. Circ. Res. 85: 47-56.
    • (1999) Circ. Res. , vol.85 , pp. 47-56
    • Muthuchamy, M.1    Pieples, K.2    Rethinasamy, P.3    Hoit, B.4    Grupp, I.5    Boivin, G.P.6
  • 30
    • 0030039383 scopus 로고    scopus 로고
    • Differential expression of C-protein isoforms in the developing heart of normal and cardiac lethal mutant axolotls (Ambystoma mexicanum)
    • Ward, S.M., Dube, D.K., Fransen, M.C., and Lemanski, L.F. (1996). Differential expression of C-protein isoforms in the developing heart of normal and cardiac lethal mutant axolotls (Ambystoma mexicanum). Dev. Dyn. 205:93-103.
    • (1996) Dev. Dyn. , vol.205 , pp. 93-103
    • Ward, S.M.1    Dube, D.K.2    Fransen, M.C.3    Lemanski, L.F.4
  • 31
    • 0016774265 scopus 로고
    • Tropomyosin coiled-coil interactions: Evidence for an unstaggered structure
    • McLachlan, A.D. and Stewart, M. (1975). Tropomyosin coiled-coil interactions: evidence for an unstaggered structure. J. Mol. Biol. 98:293-304.
    • (1975) J. Mol. Biol. , vol.98 , pp. 293-304
    • McLachlan, A.D.1    Stewart, M.2
  • 32
    • 0025130161 scopus 로고
    • Structural features in the heptad substructure and longer range repeats of two-stranded alpha-fibrous proteins
    • Conway, J.F. and Parry, D.A. (1990). Structural features in the heptad substructure and longer range repeats of two-stranded alpha-fibrous proteins. Int. J. Biol. Macromol. 12:328-334.
    • (1990) Int. J. Biol. Macromol. , vol.12 , pp. 328-334
    • Conway, J.F.1    Parry, D.A.2
  • 33
    • 0030044292 scopus 로고    scopus 로고
    • Integral repeats and a continuous coiled coil are required for binding of striated muscle tropomyosin to the regulated actin filament
    • Hitchcock-DeGregori, S.E. and An, Y. (1996). Integral repeats and a continuous coiled coil are required for binding of striated muscle tropomyosin to the regulated actin filament. J. Biol. Chem. 271:3600-3603.
    • (1996) J. Biol. Chem. , vol.271 , pp. 3600-3603
    • Hitchcock-DeGregori, S.E.1    An, Y.2
  • 34
    • 0035109415 scopus 로고    scopus 로고
    • Plasticity in skeletal, cardiac, and smooth muscle. Invited Review: Pathophysiology of cardiac muscle contraction and relaxation as a result of alterations in thin filament regulation
    • Hernandez, O.M., Housmans, P.R., and Potter, J.D. (2001). Plasticity in skeletal, cardiac, and smooth muscle. Invited Review: Pathophysiology of cardiac muscle contraction and relaxation as a result of alterations in thin filament regulation. J. Appl. Physiol. 90:1125-1136.
    • (2001) J. Appl. Physiol. , vol.90 , pp. 1125-1136
    • Hernandez, O.M.1    Housmans, P.R.2    Potter, J.D.3
  • 35
    • 0033214054 scopus 로고    scopus 로고
    • Functional consequences of troponin T mutations found in hypertrophic cardiomyopathy
    • Tobacman, L.S., Lin, D., Butters, C., Landis, C., Back, N., Pavlov, D., and Homsher, E. (1999). Functional consequences of troponin T mutations found in hypertrophic cardiomyopathy. J. Biol. Chem. 274:28,363-28,370.
    • (1999) J. Biol. Chem. , vol.274 , pp. 28363-28370
    • Tobacman, L.S.1    Lin, D.2    Butters, C.3    Landis, C.4    Back, N.5    Pavlov, D.6    Homsher, E.7
  • 36
    • 0031883848 scopus 로고    scopus 로고
    • A mutant tropomyosin that causes hypertrophic cardiomyopathy is expressed in vivo and associated with an increased calcium sensitivity
    • Bottinelli, R., Coviello, D.A., Redwood, C.S., Pelligrino, M.A., Maron, B.J., Spirito, P., et al. (1998). A mutant tropomyosin that causes hypertrophic cardiomyopathy is expressed in vivo and associated with an increased calcium sensitivity. Circ. Res. 82:106-115.
    • (1998) Circ. Res. , vol.82 , pp. 106-115
    • Bottinelli, R.1    Coviello, D.A.2    Redwood, C.S.3    Pelligrino, M.A.4    Maron, B.J.5    Spirito, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.