A mutant tropomyosin that causes hypertrophic cardiomyopathy is expressed in vivo and associated with an increased calcium sensitivity

Circulation Research

Volumn 82, Issue 1, 1998, Pages 106-115

  Bottinelli, R ^a,e   Coviello, D A ^b   Redwood, C S ^c   Pellegrino, M A ^a   Maron, B J ^f   Spirito, P ^d   Watkins, H ^c   Reggiani, C ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

^e Istituto di Fisiologia Umana   (Italy)

^f NONE

Author keywords

Ca2+ sensitivity; Familial hypertrophic cardiomyopathy; Skinned muscle fiber; Tropomyosin

Indexed keywords

MUTANT PROTEIN; TROPOMYOSIN;

ADULT; ARTICLE; CALCIUM MOBILIZATION; CASE REPORT; CONTROLLED STUDY; FAMILIAL DISEASE; FEMALE; HEART MUSCLE CELL; HUMAN; HUMAN TISSUE; HYPERTROPHIC CARDIOMYOPATHY; MALE; MUSCLE BIOPSY; MUSCLE CONTRACTILITY; PRIORITY JOURNAL; SARCOMERE; SKINNED MUSCLE FIBER; VASTUS LATERALIS MUSCLE;

EID: 0031883848     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.82.1.106     Document Type: Article

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