Domain swapping of a llama VHH domain builds a crystal-wide β-sheet structure

FEBS Letters

Volumn 564, Issue 1-2, 2004, Pages 35-40

  Spinelli, Silvia ^a   Desmyter, Aline ^a   Frenken, Leon ^b   Verrips, Theo ^b,c   Tegoni, Mariella ^a   Cambillau, Christian ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b UNILEVER RESEARCH VLAARDINGEN   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Camelid heavy chain antibody VH domain; CDR, complementarity determining region; Crystal structure; Domain swapping; FU, functional unit of domain swapped dimers; Immunoglobulin; Red dye hapten; VHH, camelid heavy chain antibody VH domain

Indexed keywords

AMYLOID; ANTIBODY; ANTIGEN; HAPTEN; IMMUNOGLOBULIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BETA SHEET; CAMEL; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMORAL IMMUNITY; IMMUNE SYSTEM; IMMUNOGLOBULIN STRUCTURE; MALE; MOLECULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; CAMELIDS, NEW WORLD; COMPLEMENTARITY DETERMINING REGIONS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; HAPTENS; IMMUNOGLOBULIN HEAVY CHAINS; MALE; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT;

LAMA GLAMA; MAMMALIA;

EID: 1842850634     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(04)00304-7     Document Type: Article

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