Loss of splice consensus signal is responsible for the removal of the entire C(H)1 domain of the functional camel IGG2A heavy-chain antibodies

Molecular Immunology

Volumn 36, Issue 8, 1999, Pages 515-524

  Khong Nguyen, Viet ^a   Hamers, Raymond ^a   Wyns, Lode ^a   Muyldermans, Serge ^a  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

Camel; Constant heavy chain; Heavy chain antibodies; Splicing

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN;

ANIMAL TISSUE; ANTIBODY STRUCTURE; ARTICLE; CAMEL; EXON; GENE LIBRARY; GENETIC VARIABILITY; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN STRUCTURE; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; RNA SPLICING; TRANSPOSON;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CAMELS; CATTLE; CELL MEMBRANE; CONSENSUS SEQUENCE; CYTOPLASM; DNA, COMPLEMENTARY; EXONS; GENES, IMMUNOGLOBULIN; HINGE EXONS; HUMANS; IMMUNOGLOBULIN CONSTANT REGIONS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN SWITCH REGION; INTRONS; MICE; MOLECULAR SEQUENCE DATA; RABBITS; RATS; RESTRICTION MAPPING; RNA SPLICING; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPECIES SPECIFICITY;

ANIMALIA; CAMELIDAE; CAMELUS DROMEDARIUS; MAMMALIA;

EID: 0345425685     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(99)00067-X     Document Type: Article

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