Inhibition of mammalian legumain by Michael acceptors and AzaAsn-halomethylketones

Biological Chemistry

Volumn 383, Issue 7-8, 2002, Pages 1205-1214

  Niestroj, André J ^a   Feußner, Kirstin ^a   Heiser, Ulrich ^a   Dando, Pam M ^a   Barrett, Alan ^a   Gerhartz, Bernd ^a   Demuth, Hans Ulrich ^a  

^a PROBIODRUG AG   (Germany)

Author keywords

, unsaturated esters; Azaasparagine; Benzoyloxymethylketone; Cystein protease; Halomethylketone; Legumain; Michael acceptos

Indexed keywords

ALLYL COMPOUND; AMIDE; ASPARAGINE; CASPASE; CATHEPSIN B; CYSTATIN C; ENZYME INHIBITOR; ESTER; GINGIPAIN R; KETONE DERIVATIVE; LEGUMAIN; LYSOSOME ENZYME; PAPAIN; PEPTIDASE; UNCLASSIFIED DRUG; CYSTEINE PROTEINASE; FLUORESCENT DYE; KETONE; OLIGOPEPTIDE; PROTEINASE INHIBITOR;

ARTICLE; CHEMICAL REACTION; CLASSIFICATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYCLIZATION; ENZYME INHIBITION; ENZYME STRUCTURE; MOLECULAR SIZE; NONHUMAN; PRIORITY JOURNAL; SYNTHESIS; ANIMAL; CHEMISTRY; KINETICS; STRUCTURE ACTIVITY RELATION; SWINE;

KOBUS; MAMMALIA; SUIDAE;

ANIMALS; ASPARAGINE; CYSTEINE ENDOPEPTIDASES; FLUORESCENT DYES; KETONES; KINETICS; OLIGOPEPTIDES; PROTEASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE;

EID: 1842831877     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2002.133     Document Type: Article

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