Flexible N-terminal Region of Prion Protein Influences Conformation of Protease-resistant Prion Protein Isoforms Associated with Cross-species Scrapie Infection in Vivo and in Vitro

Journal of Biological Chemistry

Volumn 279, Issue 14, 2004, Pages 13689-13695

  Lawson, Victoria A ^a,b   Priola, Suzette A ^a   Meade White, Kimberly ^a   Lawson, McKinley ^a   Chesebro, Bruce ^a,c  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; DISEASES; ENZYMES; MOLECULAR STRUCTURE; NEUROLOGY; PATHOLOGY;

CELL FREE CONVERSION ASSAY; TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHY (TSE) DISEASES;

BIOCHEMICAL ENGINEERING;

PRION PROTEIN; PROTEINASE;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CARBOXY TERMINAL SEQUENCE; DISEASE TRANSMISSION; GENE DELETION; HAMSTER; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROTEIN CONFORMATION; SCRAPIE; SPECIES DIFFERENCE;

ANIMALS; BRAIN; CELL-FREE SYSTEM; CRICETINAE; ENDOPEPTIDASES; ISOMERISM; MICE; PEPTIDE FRAGMENTS; PRIONS; PROTEIN STRUCTURE, TERTIARY; SCRAPIE; SPECIES SPECIFICITY;

ANIMALIA; CRICETINAE;

EID: 1842791529     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M303697200     Document Type: Article

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