Inhibition of carcinogen-bioactivating cytochrome P450 1 isoforms by amiloride derivatives

Biochemical Pharmacology

Volumn 67, Issue 9, 2004, Pages 1711-1719

  Sparfel, Lydie ^a   Huc, Laurence ^a   Le Vee, Marc ^a   Desille, Mireille ^a   Lagadic Gossmann, Dominique ^a   Fardel, Olivier ^a  

^a UNIVERSITÉ DE RENNES 1   (France)

Author keywords

5 (N ethyl N isopropyl) amiloride; 5 (N methyl N isobutyl) amiloride; Benzo(a)pyrene; BP; CYP; Cytochrome P450; EIPA; EROD; Ethoxyresorufine O deethylase; MIA; PAH; PBS; Phosphate buffered saline; Polycyclic aromatic hydrocarbon; TCDD

Indexed keywords

5 (N ETHYL N ISOPROPYL)AMILORIDE; AMILORIDE; AMILORIDE DERIVATIVE; BENZO[A]PYRENE; CARIPORIDE; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; ETHOXYRESORUFIN DEETHYLASE; MESSENGER RNA; POLYCYCLIC AROMATIC HYDROCARBON;

ANIMAL CELL; ARTICLE; CELL CULTURE; DNA ADDUCT; DOSE RESPONSE; DRUG EFFECT; DRUG POTENCY; ENZYME ACTIVITY; EPITHELIUM CELL; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER CELL; MALE; MICROSOME; NONHUMAN; PRIORITY JOURNAL; RAT;

AMILORIDE; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BENZO(A)PYRENE; CYTOCHROME P-450 CYP1A1; ENZYME INHIBITORS; GENE EXPRESSION; ISOENZYMES; MALE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 1842785906     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.01.005     Document Type: Article

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