메뉴 건너뛰기




Volumn 150, Issue 1-2, 2004, Pages 70-79

Bone marrow-derived versus parenchymal sources of inducible nitric oxide synthase in experimental autoimmune encephalomyelitis

Author keywords

Central nervous system; CNS; Delayed onset; EAE; Experimental autoimmune encephalomyelitis; Inducible nitric oxide synthase; iNOS; Knockout; KO; MOG; MS; Multiple sclerosis; Myelin oligodendrocyte glycoprotein; Nitric oxide; Phox; Radiation chimeras; Superoxide

Indexed keywords

NITRIC OXIDE SYNTHASE;

EID: 1842636947     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2004.01.020     Document Type: Article
Times cited : (14)

References (56)
  • 1
    • 0035958826 scopus 로고    scopus 로고
    • Pertussis toxin-induced hyperacute autoimmune encephalomyelitis in Lewis rats is correlated with increased expression of inducible nitric oxide synthase and tumor necrosis factor alpha
    • Ahn M., Kang J., Lee Y., Riu K., Kim Y., Jee Y., Matsumoto Y., Shin T. Pertussis toxin-induced hyperacute autoimmune encephalomyelitis in Lewis rats is correlated with increased expression of inducible nitric oxide synthase and tumor necrosis factor alpha. Neurosci. Lett. 308:2001;41-44.
    • (2001) Neurosci. Lett. , vol.308 , pp. 41-44
    • Ahn, M.1    Kang, J.2    Lee, Y.3    Riu, K.4    Kim, Y.5    Jee, Y.6    Matsumoto, Y.7    Shin, T.8
  • 3
    • 0036089107 scopus 로고    scopus 로고
    • Inhibition of leukocyte rolling by nitric oxide during sepsis leads to reduced migration of active microbicidal neutrophils
    • Benjamim C.F., Silva J.S., Fortes Z.B., Oliveira M.A., Ferreira S.H., Cunha F.Q. Inhibition of leukocyte rolling by nitric oxide during sepsis leads to reduced migration of active microbicidal neutrophils. Infect. Immun. 70:2002;3602-3610.
    • (2002) Infect. Immun. , vol.70 , pp. 3602-3610
    • Benjamim, C.F.1    Silva, J.S.2    Fortes, Z.B.3    Oliveira, M.A.4    Ferreira, S.H.5    Cunha, F.Q.6
  • 4
    • 0033559897 scopus 로고    scopus 로고
    • Peroxynitrite inhibits T lymphocyte activation and proliferation by promoting impairment of tyrosine phosphorylation and peroxynitrite-driven apoptotic death
    • Brito C., Naviliat M., Tiscornia A.C., Vuillier F., Gualco G., Dighiero G., Radi R., Cayota A.M. Peroxynitrite inhibits T lymphocyte activation and proliferation by promoting impairment of tyrosine phosphorylation and peroxynitrite-driven apoptotic death. J. Immunol. 162:1999;3356-3366.
    • (1999) J. Immunol. , vol.162 , pp. 3356-3366
    • Brito, C.1    Naviliat, M.2    Tiscornia, A.C.3    Vuillier, F.4    Gualco, G.5    Dighiero, G.6    Radi, R.7    Cayota, A.M.8
  • 5
    • 0029319566 scopus 로고
    • Cytokine localization in multiple sclerosis lesions: Correlation with adhesion molecule expression and reactive nitrogen species
    • Brosnan C.F., Cannella B., Battistini L., Raine C.S. Cytokine localization in multiple sclerosis lesions: correlation with adhesion molecule expression and reactive nitrogen species. Neurology. 45:1995;S16-S21.
    • (1995) Neurology , vol.45 , pp. 16-S21
    • Brosnan, C.F.1    Cannella, B.2    Battistini, L.3    Raine, C.S.4
  • 6
    • 0037110706 scopus 로고    scopus 로고
    • Nitric oxide synthase is present in the cerebrospinal fluid of patients with active multiple sclerosis and is associated with increases in cerebrospinal fluid protein nitrotyrosine and S-nitrosothiols and with changes in glutathione levels
    • Calabrese V., Scapagnini G., Ravagna A., Bella R., Foresti R., Bates T.E., Giuffrida Stella A.M., Pennisi G. Nitric oxide synthase is present in the cerebrospinal fluid of patients with active multiple sclerosis and is associated with increases in cerebrospinal fluid protein nitrotyrosine and S-nitrosothiols and with changes in glutathione levels. J. Neurosci. Res. 70:2002;580-587.
    • (2002) J. Neurosci. Res. , vol.70 , pp. 580-587
    • Calabrese, V.1    Scapagnini, G.2    Ravagna, A.3    Bella, R.4    Foresti, R.5    Bates, T.E.6    Giuffrida Stella, A.M.7    Pennisi, G.8
  • 7
    • 0030561017 scopus 로고    scopus 로고
    • Exacerbation of lymphocytic choriomeningitis in mice treated with the inducible nitric oxide synthase inhibitor aminoguanidine
    • Campbell I.L. Exacerbation of lymphocytic choriomeningitis in mice treated with the inducible nitric oxide synthase inhibitor aminoguanidine. J. Neuroimmunol. 71:1996;31-36.
    • (1996) J. Neuroimmunol. , vol.71 , pp. 31-36
    • Campbell, I.L.1
  • 8
    • 0033711655 scopus 로고    scopus 로고
    • Protection against TNF-induced lethal shock by soluble guanylate cyclase inhibition requires functional inducible nitric oxide synthase
    • Cauwels A., Van Molle W., Janssen B., Everaerdt B., Huang P., Fiers W., Brouckaert P. Protection against TNF-induced lethal shock by soluble guanylate cyclase inhibition requires functional inducible nitric oxide synthase. Immunity. 13:2000;223-231.
    • (2000) Immunity , vol.13 , pp. 223-231
    • Cauwels, A.1    Van Molle, W.2    Janssen, B.3    Everaerdt, B.4    Huang, P.5    Fiers, W.6    Brouckaert, P.7
  • 9
    • 0034601012 scopus 로고    scopus 로고
    • Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis
    • Chu C.Q., Wittmer S., Dalton D.K. Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis. J. Exp. Med. 192:2000;123-128.
    • (2000) J. Exp. Med. , vol.192 , pp. 123-128
    • Chu, C.Q.1    Wittmer, S.2    Dalton, D.K.3
  • 10
    • 0030560858 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase gene expression and enzyme activity correlate with disease activity in murine experimental autoimmune encephalomyelitis
    • Cross A.H., Keeling R.M., Goorha S., San M., Rodi C., Wyatt P.S., Manning P.T., Misko T.P. Inducible nitric oxide synthase gene expression and enzyme activity correlate with disease activity in murine experimental autoimmune encephalomyelitis. J. Neuroimmunol. 71:1996;145-153.
    • (1996) J. Neuroimmunol. , vol.71 , pp. 145-153
    • Cross, A.H.1    Keeling, R.M.2    Goorha, S.3    San, M.4    Rodi, C.5    Wyatt, P.S.6    Manning, P.T.7    Misko, T.P.8
  • 11
    • 0031457801 scopus 로고    scopus 로고
    • Evidence for the production of peroxynitrite in inflammatory CNS demyelination
    • Cross A.H., Manning P.T., Stern M.K., Misko T.P. Evidence for the production of peroxynitrite in inflammatory CNS demyelination. J. Neuroimmunol. 80:1997;121-130.
    • (1997) J. Neuroimmunol. , vol.80 , pp. 121-130
    • Cross, A.H.1    Manning, P.T.2    Stern, M.K.3    Misko, T.P.4
  • 12
    • 0034600788 scopus 로고    scopus 로고
    • Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells
    • Dalton D.K., Haynes L., Chu C.Q., Swain S.L., Wittmer S. Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells. J. Exp. Med. 192:2000;117-122.
    • (2000) J. Exp. Med. , vol.192 , pp. 117-122
    • Dalton, D.K.1    Haynes, L.2    Chu, C.Q.3    Swain, S.L.4    Wittmer, S.5
  • 13
    • 0037131412 scopus 로고    scopus 로고
    • Myelin basic protein-primed T Cells induce nitric oxide synthase in microglial cells. Implications for multiple sclerosis
    • Dasgupta S., Jana M., Liu X., Pahan K. Myelin basic protein-primed T Cells induce nitric oxide synthase in microglial cells. Implications for multiple sclerosis. J. Biol. Chem. 277:2002;39327-39333.
    • (2002) J. Biol. Chem. , vol.277 , pp. 39327-39333
    • Dasgupta, S.1    Jana, M.2    Liu, X.3    Pahan, K.4
  • 14
    • 0029018513 scopus 로고
    • The modulation of IL-6 and TNF-alpha release by nitric oxide following stimulation of J774 cells with LPS and IFN-gamma
    • Deakin A.M., Payne A.N., Whittle B.J., Moncada S. The modulation of IL-6 and TNF-alpha release by nitric oxide following stimulation of J774 cells with LPS and IFN-gamma. Cytokine. 7:1995;408-416.
    • (1995) Cytokine , vol.7 , pp. 408-416
    • Deakin, A.M.1    Payne, A.N.2    Whittle, B.J.3    Moncada, S.4
  • 15
    • 0032520788 scopus 로고    scopus 로고
    • Antisense knockdown of inducible nitric oxide synthase inhibits induction of experimental autoimmune encephalomyelitis in SJL/J mice
    • Ding M., Zhang M., Wong J.L., Rogers N.E., Ignarro L.J., Voskuhl R.R. Antisense knockdown of inducible nitric oxide synthase inhibits induction of experimental autoimmune encephalomyelitis in SJL/J mice. J. Immunol. 160:1998;2560-2564.
    • (1998) J. Immunol. , vol.160 , pp. 2560-2564
    • Ding, M.1    Zhang, M.2    Wong, J.L.3    Rogers, N.E.4    Ignarro, L.J.5    Voskuhl, R.R.6
  • 18
    • 0028841168 scopus 로고
    • Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1
    • Fuentes M.E., Durham S.K., Swerdel M.R., Lewin A.C., Barton D.S., Megill J.R., Bravo R., Lira S.A. Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1. J. Immunol. 155:1995;5769-5776.
    • (1995) J. Immunol. , vol.155 , pp. 5769-5776
    • Fuentes, M.E.1    Durham, S.K.2    Swerdel, M.R.3    Lewin, A.C.4    Barton, D.S.5    Megill, J.R.6    Bravo, R.7    Lira, S.A.8
  • 19
    • 0034255743 scopus 로고    scopus 로고
    • Elevated interferon-gamma in CNS inflammatory disease: A potential complication for bone marrow reconstitution in MS
    • Hassan-Zahraee M., Tran E.H., Bourbonniere L., Owens T. Elevated interferon-gamma in CNS inflammatory disease: a potential complication for bone marrow reconstitution in MS. J. Neuroimmunol. 108:2000;40-44.
    • (2000) J. Neuroimmunol. , vol.108 , pp. 40-44
    • Hassan-Zahraee, M.1    Tran, E.H.2    Bourbonniere, L.3    Owens, T.4
  • 20
    • 0036635706 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase (iNOS) in endotoxemia: Chimeric mice reveal different cellular sources in various tissues
    • Hickey M.J., Sihota E., Amrani A., Santamaria P., Zbytnuik L.D., Ng E.S., Ho W., Sharkey K.A., Kubes P. Inducible nitric oxide synthase (iNOS) in endotoxemia: chimeric mice reveal different cellular sources in various tissues. FASEB J. 16:2002;1141-1143.
    • (2002) FASEB J. , vol.16 , pp. 1141-1143
    • Hickey, M.J.1    Sihota, E.2    Amrani, A.3    Santamaria, P.4    Zbytnuik, L.D.5    Ng, E.S.6    Ho, W.7    Sharkey, K.A.8    Kubes, P.9
  • 21
    • 0035806322 scopus 로고    scopus 로고
    • Adjuvant immunotherapy is dependent on inducible nitric oxide synthase
    • Kahn D.A., Archer D.C., Gold D.P., Kelly C.J. Adjuvant immunotherapy is dependent on inducible nitric oxide synthase. J. Exp. Med. 193:2001;1261-1268.
    • (2001) J. Exp. Med. , vol.193 , pp. 1261-1268
    • Kahn, D.A.1    Archer, D.C.2    Gold, D.P.3    Kelly, C.J.4
  • 23
    • 0038917435 scopus 로고    scopus 로고
    • Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting
    • Korner H., Riminton D.S., Strickland D.H., Lemckert F.A., Pollard J.D., Sedgwick J.D. Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting. J. Exp. Med. 186:1997;1585-1590.
    • (1997) J. Exp. Med. , vol.186 , pp. 1585-1590
    • Korner, H.1    Riminton, D.S.2    Strickland, D.H.3    Lemckert, F.A.4    Pollard, J.D.5    Sedgwick, J.D.6
  • 25
    • 0034661719 scopus 로고    scopus 로고
    • Gr-1+ myeloid cells derived from tumor-bearing mice inhibit primary T cell activation induced through CD3/CD28 costimulation
    • Kusmartsev S.A., Li Y., Chen S.H. Gr-1+ myeloid cells derived from tumor-bearing mice inhibit primary T cell activation induced through CD3/CD28 costimulation. J. Immunol. 165:2000;779-785.
    • (2000) J. Immunol. , vol.165 , pp. 779-785
    • Kusmartsev, S.A.1    Li, Y.2    Chen, S.H.3
  • 26
    • 0028889439 scopus 로고
    • Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death
    • Laubach V.E., Shesely E.G., Smithies O., Sherman P.A. Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death. Proc. Natl. Acad. Sci. U. S. A. 92:1995;10688-10692.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 10688-10692
    • Laubach, V.E.1    Shesely, E.G.2    Smithies, O.3    Sherman, P.A.4
  • 27
    • 0035260572 scopus 로고    scopus 로고
    • Genetic requirement of p47phox for superoxide production by murine microglia
    • Lavigne M.C., Malech H.L., Holland S.M., Leto T.L. Genetic requirement of p47phox for superoxide production by murine microglia. FASEB J. 15:2001;285-287.
    • (2001) FASEB J. , vol.15 , pp. 285-287
    • Lavigne, M.C.1    Malech, H.L.2    Holland, S.M.3    Leto, T.L.4
  • 28
    • 0020446988 scopus 로고
    • Acute experimental autoimmune encephalomyelitis in mice: I. Adjuvant action of Bordetella pertussis is due to vasoactive amine sensitization and increased vascular permeability of the central nervous system
    • Linthicum D.S., Munoz J.J., Blaskett A. Acute experimental autoimmune encephalomyelitis in mice: I. Adjuvant action of Bordetella pertussis is due to vasoactive amine sensitization and increased vascular permeability of the central nervous system. Cell Immunol. 73:1982;299-310.
    • (1982) Cell Immunol. , vol.73 , pp. 299-310
    • Linthicum, D.S.1    Munoz, J.J.2    Blaskett, A.3
  • 30
    • 0037114171 scopus 로고    scopus 로고
    • Interactions between hemopoietically derived TNF and central nervous system-resident glial chemokines underlie initiation of autoimmune inflammation in the brain
    • Murphy C.A., Hoek R.M., Wiekowski M.T., Lira S.A., Sedgwick J.D. Interactions between hemopoietically derived TNF and central nervous system-resident glial chemokines underlie initiation of autoimmune inflammation in the brain. J. Immunol. 169:2002;7054-7062.
    • (2002) J. Immunol. , vol.169 , pp. 7054-7062
    • Murphy, C.A.1    Hoek, R.M.2    Wiekowski, M.T.3    Lira, S.A.4    Sedgwick, J.D.5
  • 31
    • 0034573392 scopus 로고    scopus 로고
    • Induction and activation by zinc of NADPH oxidase in cultured cortical neurons and astrocytes
    • Noh K.M., Koh J.Y. Induction and activation by zinc of NADPH oxidase in cultured cortical neurons and astrocytes. J. Neurosci. 20:2000;RC111.
    • (2000) J. Neurosci. , vol.20 , pp. 111
    • Noh, K.M.1    Koh, J.Y.2
  • 32
    • 0031056103 scopus 로고    scopus 로고
    • Nitric oxide via an inducible isoform of nitric oxide synthase is a possible factor to eliminate inflammatory cells from the central nervous system of mice with experimental allergic encephalomyelitis
    • Okuda Y., Sakoda S., Fujimura H., Yanagihara T. Nitric oxide via an inducible isoform of nitric oxide synthase is a possible factor to eliminate inflammatory cells from the central nervous system of mice with experimental allergic encephalomyelitis. J. Neuroimmunol. 73:1997;107-116.
    • (1997) J. Neuroimmunol. , vol.73 , pp. 107-116
    • Okuda, Y.1    Sakoda, S.2    Fujimura, H.3    Yanagihara, T.4
  • 33
    • 0031859370 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase and nitrotyrosine are found in monocytes/macrophages and/or astrocytes in acute, but not in chronic, multiple sclerosis
    • Oleszak E.L., Zaczynska E., Bhattacharjee M., Butunoi C., Legido A., Katsetos C.D. Inducible nitric oxide synthase and nitrotyrosine are found in monocytes/macrophages and/or astrocytes in acute, but not in chronic, multiple sclerosis. Clin. Diagn. Lab. Immunol. 5:1998;438-445.
    • (1998) Clin. Diagn. Lab. Immunol. , vol.5 , pp. 438-445
    • Oleszak, E.L.1    Zaczynska, E.2    Bhattacharjee, M.3    Butunoi, C.4    Legido, A.5    Katsetos, C.D.6
  • 34
    • 0028959239 scopus 로고
    • The immunology of multiple sclerosis and its animal model, experimental allergic encephalomyelitis
    • Owens T., Sriram S. The immunology of multiple sclerosis and its animal model, experimental allergic encephalomyelitis. Neurol. Clin. 13:1995;51-73.
    • (1995) Neurol. Clin. , vol.13 , pp. 51-73
    • Owens, T.1    Sriram, S.2
  • 35
    • 0035128996 scopus 로고    scopus 로고
    • Genetic models for CNS inflammation
    • Owens T., Wekerle H., Antel J. Genetic models for CNS inflammation. Nat. Med. 7:2001;161-166.
    • (2001) Nat. Med. , vol.7 , pp. 161-166
    • Owens, T.1    Wekerle, H.2    Antel, J.3
  • 36
    • 0029005508 scopus 로고
    • Nitric oxide and cGMP analogs activate transcription from AP-1-responsive promoters in mammalian cells
    • Pilz R.B., Suhasini M., Idriss S., Meinkoth J.L., Boss G.R. Nitric oxide and cGMP analogs activate transcription from AP-1-responsive promoters in mammalian cells. FASEB J. 9:1995;552-558.
    • (1995) FASEB J. , vol.9 , pp. 552-558
    • Pilz, R.B.1    Suhasini, M.2    Idriss, S.3    Meinkoth, J.L.4    Boss, G.R.5
  • 37
    • 77956981608 scopus 로고
    • Selective enrichment of Th1 CD45RBlow CD4+T cells in autoimmune infiltrates in experimental allergic encephalomyelitis
    • Renno T., Zeine R., Girard J.M., Gillani S., Dodelet V., Owens T. Selective enrichment of Th1 CD45RBlow CD4+T cells in autoimmune infiltrates in experimental allergic encephalomyelitis. Int. Immunol. 6:1994;347-354.
    • (1994) Int. Immunol. , vol.6 , pp. 347-354
    • Renno, T.1    Zeine, R.2    Girard, J.M.3    Gillani, S.4    Dodelet, V.5    Owens, T.6
  • 39
    • 0028872327 scopus 로고
    • Reactive oxygen species are involved in the pathogenesis of experimental allergic encephalomyelitis in Lewis rats
    • Ruuls S.R., Bauer J., Sontrop K., Huitinga I., t Hart B.A., Dijkstra C.D. Reactive oxygen species are involved in the pathogenesis of experimental allergic encephalomyelitis in Lewis rats. J. Neuroimmunol. 56:1995;207-217.
    • (1995) J. Neuroimmunol. , vol.56 , pp. 207-217
    • Ruuls, S.R.1    Bauer, J.2    Sontrop, K.3    Huitinga, I.4    Hart B A, T.5    Dijkstra, C.D.6
  • 40
    • 0031960227 scopus 로고    scopus 로고
    • Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis
    • Sahrbacher U.C., Lechner F., Eugster H.P., Frei K., Lassmann H., Fontana A. Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis. Eur. J. Immunol. 28:1998;1332-1338.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 1332-1338
    • Sahrbacher, U.C.1    Lechner, F.2    Eugster, H.P.3    Frei, K.4    Lassmann, H.5    Fontana, A.6
  • 42
    • 0013292906 scopus 로고    scopus 로고
    • The role of nitric oxide in multiple sclerosis
    • Smith K.J., Lassmann H. The role of nitric oxide in multiple sclerosis. Lancet Neurol. 1:2002;232-241.
    • (2002) Lancet Neurol. , vol.1 , pp. 232-241
    • Smith, K.J.1    Lassmann, H.2
  • 43
    • 0033579881 scopus 로고    scopus 로고
    • Interleukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon gamma, nitric oxide, and apoptosis
    • Tarrant T.K., Silver P.B., Wahlsten J.L., Rizzo L.V., Chan C.C., Wiggert B., Caspi R.R. Interleukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon gamma, nitric oxide, and apoptosis. J. Exp. Med. 189:1999;219-230.
    • (1999) J. Exp. Med. , vol.189 , pp. 219-230
    • Tarrant, T.K.1    Silver, P.B.2    Wahlsten, J.L.3    Rizzo, L.V.4    Chan, C.C.5    Wiggert, B.6    Caspi, R.R.7
  • 45
    • 0030890185 scopus 로고    scopus 로고
    • Astrocytes and microglia express inducible nitric oxide synthase in mice with experimental allergic encephalomyelitis
    • Tran E.H., Hardin-Pouzet H., Verge G., Owens T. Astrocytes and microglia express inducible nitric oxide synthase in mice with experimental allergic encephalomyelitis. J. Neuroimmunol. 74:1997;121-129.
    • (1997) J. Neuroimmunol. , vol.74 , pp. 121-129
    • Tran, E.H.1    Hardin-Pouzet, H.2    Verge, G.3    Owens, T.4
  • 46
    • 0032193213 scopus 로고    scopus 로고
    • Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice
    • Tran E.H., Hoekstra K., van Rooijen N., Dijkstra C.D., Owens T. Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice. J. Immunol. 161:1998;3767-3775.
    • (1998) J. Immunol. , vol.161 , pp. 3767-3775
    • Tran, E.H.1    Hoekstra, K.2    Van Rooijen, N.3    Dijkstra, C.D.4    Owens, T.5
  • 47
    • 0034162486 scopus 로고    scopus 로고
    • IFN-gamma shapes immune invasion of the central nervous system via regulation of chemokines
    • Tran E.H., Prince E.N., Owens T. IFN-gamma shapes immune invasion of the central nervous system via regulation of chemokines. J. Immunol. 164:2000;2759-2768.
    • (2000) J. Immunol. , vol.164 , pp. 2759-2768
    • Tran, E.H.1    Prince, E.N.2    Owens, T.3
  • 48
    • 0030787471 scopus 로고    scopus 로고
    • Extensive peroxynitrite activity during progressive stages of central nervous system inflammation
    • van der Veen R.C., Hinton D.R., Incardonna F., Hofman F.M. Extensive peroxynitrite activity during progressive stages of central nervous system inflammation. J. Neuroimmunol. 77:1997;1-7.
    • (1997) J. Neuroimmunol. , vol.77 , pp. 1-7
    • Van Der Veen, R.C.1    Hinton, D.R.2    Incardonna, F.3    Hofman, F.M.4
  • 49
    • 0034627986 scopus 로고    scopus 로고
    • Macrophage-derived nitric oxide inhibits the proliferation of activated T helper cells and is induced during antigenic stimulation of resting T cells
    • van der Veen R.C., Dietlin T.A., Dixon Gray J., Gilmore W. Macrophage-derived nitric oxide inhibits the proliferation of activated T helper cells and is induced during antigenic stimulation of resting T cells. Cell Immunol. 199:2000;43-49.
    • (2000) Cell Immunol. , vol.199 , pp. 43-49
    • Van Der Veen, R.C.1    Dietlin, T.A.2    Dixon Gray, J.3    Gilmore, W.4
  • 50
    • 0034658353 scopus 로고    scopus 로고
    • Superoxide prevents nitric oxide-mediated suppression of helper T lymphocytes: Decreased autoimmune encephalomyelitis in nicotinamide adenine dinucleotide phosphate oxidase knockout mice
    • van Der Veen R.C., Dietlin T.A., Hofman F.M., Pen L., Segal B.H., Holland S.M. Superoxide prevents nitric oxide-mediated suppression of helper T lymphocytes: decreased autoimmune encephalomyelitis in nicotinamide adenine dinucleotide phosphate oxidase knockout mice. J. Immunol. 164:2000;5177-5183.
    • (2000) J. Immunol. , vol.164 , pp. 5177-5183
    • Van Der Veen, R.C.1    Dietlin, T.A.2    Hofman, F.M.3    Pen, L.4    Segal, B.H.5    Holland, S.M.6
  • 51
    • 0034679577 scopus 로고    scopus 로고
    • Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis: I. Effects on microbial killing by activated peritoneal macrophages in vitro
    • Vazquez-Torres A., Jones-Carson J., Mastroeni P., Ischiropoulos H., Fang F.C. Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis: I. Effects on microbial killing by activated peritoneal macrophages in vitro. J. Exp. Med. 192:2000;227-236.
    • (2000) J. Exp. Med. , vol.192 , pp. 227-236
    • Vazquez-Torres, A.1    Jones-Carson, J.2    Mastroeni, P.3    Ischiropoulos, H.4    Fang, F.C.5
  • 52
    • 0034609968 scopus 로고    scopus 로고
    • T-cell function and migration. Two sides of the same coin
    • von Andrian U.H., Mackay C.R. T-cell function and migration. Two sides of the same coin. N. Engl. J. Med. 343:2000;1020-1034.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 1020-1034
    • Von Andrian, U.H.1    MacKay, C.R.2
  • 53
    • 0034671635 scopus 로고    scopus 로고
    • Molecular mechanisms of high-dose antigen therapy in experimental autoimmune encephalomyelitis: Rapid induction of Th1-type cytokines and inducible nitric oxide synthase
    • Weishaupt A., Jander S., Bruck W., Kuhlmann T., Stienekemeier M., Hartung T., Toyka K.V., Stoll G., Gold R. Molecular mechanisms of high-dose antigen therapy in experimental autoimmune encephalomyelitis: rapid induction of Th1-type cytokines and inducible nitric oxide synthase. J. Immunol. 165:2000;7157-7163.
    • (2000) J. Immunol. , vol.165 , pp. 7157-7163
    • Weishaupt, A.1    Jander, S.2    Bruck, W.3    Kuhlmann, T.4    Stienekemeier, M.5    Hartung, T.6    Toyka, K.V.7    Stoll, G.8    Gold, R.9
  • 54
    • 0033571331 scopus 로고    scopus 로고
    • IFN-gamma is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: A possible role for nitric oxide
    • Willenborg D.O., Fordham S.A., Staykova M.A., Ramshaw I.A., Cowden W.B. IFN-gamma is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: a possible role for nitric oxide. J. Immunol. 163:1999;5278-5286.
    • (1999) J. Immunol. , vol.163 , pp. 5278-5286
    • Willenborg, D.O.1    Fordham, S.A.2    Staykova, M.A.3    Ramshaw, I.A.4    Cowden, W.B.5
  • 55
    • 0033400628 scopus 로고    scopus 로고
    • Our shifting understanding of the role of nitric oxide in autoimmune encephalomyelitis: A review
    • Willenborg D.O., Staykova M.A., Cowden W.B. Our shifting understanding of the role of nitric oxide in autoimmune encephalomyelitis: a review. J. Neuroimmunol. 100:1999;21-35.
    • (1999) J. Neuroimmunol. , vol.100 , pp. 21-35
    • Willenborg, D.O.1    Staykova, M.A.2    Cowden, W.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.