Overexpression of the Ikaros 6 isoform is restricted to t(4;11) acute lymphoblastic leukaemia in children and infants and has a role in B-cell survival

British Journal of Haematology

Volumn 125, Issue 1, 2004, Pages 31-37

  Ruiz, Anna ^a   Jiang, Jie ^a   Kempski, Helena ^a   Brady, Hugh J M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Dominant negative; Ikaros; Isoform; Leukaemia; t(4; 11)

Indexed keywords

ISOPROTEIN; ZINC FINGER PROTEIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; B LYMPHOCYTE; CELL SURVIVAL; CHILD; CHROMOSOME TRANSLOCATION 11; CHROMOSOME TRANSLOCATION 4; CLINICAL ARTICLE; GENE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IKAROS GENE; INFANT; LEUKEMOGENESIS; PENETRANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

B-LYMPHOCYTES; CELL DIVISION; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; CHILD; CHILD, PRESCHOOL; CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 4; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION; HUMANS; IKAROS TRANSCRIPTION FACTOR; INFANT; INTERLEUKIN-3; LEUKEMIA, B-CELL, ACUTE; LEUKEMIA, LYMPHOCYTIC, ACUTE; MALE; NEOPLASM PROTEINS; PROTEIN ISOFORMS; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC; TUMOR CELLS, CULTURED;

EID: 1842506138     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2004.04854.x     Document Type: Article

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