Enhanced dispersibility and deposition of spray-dried powders for pulmonary gene therapy

Journal of Drug Targeting

Volumn 11, Issue 7, 2003, Pages 425-432

  Li, Hao Ying ^a   Neill, Helen ^a   Innocent, Rebecca ^a   Seville, Peter ^b   Williamson, Ian ^c   Birchall, James C ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b ASTON UNIVERSITY   (United Kingdom)

^c ANEURIN BEVAN UNIVERSITY HEALTH BOARD   (United Kingdom)

Author keywords

Leucin; LPD complex; Non viral gene therapy; Pulmonary deposition; Spray drying

Indexed keywords

LACTOSE; LEUCINE; LIPID; PLASMID DNA; POLYCATION;

AGAR GEL ELECTROPHORESIS; ARTICLE; CONTROLLED STUDY; DEVICE; DISPERSION; DRUG FORMULATION; DRUG TARGETING; DRY DEPOSITION; DRY POWDER; EXPRESSION VECTOR; FREEZE DRYING; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIQUID; LUNG DISEASE; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING;

CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; DNA; DRUG COMPOUNDING; ELECTROPHORESIS, AGAR GEL; EXCIPIENTS; FLOW CYTOMETRY; FREEZE DRYING; GENE EXPRESSION; GENE THERAPY; HUMANS; LACTOSE; LEUCINE; LUNG; LUNG DISEASES; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; POWDERS; SURFACE PROPERTIES; TRANSFECTION;

EID: 1842483585     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/10611860410001659786     Document Type: Article

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