Differences in the operational characteristics of the human recombinant somatostatin receptor types, sst1 and sst2, in mouse fibroblast (Ltk-) cells

British Journal of Pharmacology

Volumn 117, Issue 4, 1996, Pages 639-646

  Castro, Sandra W ^a   Buell, Gary ^b   Feniuk, Wasyl ^a   Humphrey, Patrick P A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b GLAXO INST FOR MOLECULAR BIOLOGY   (Switzerland)

Author keywords

Extracellular acidification; Microphysiometry; Somatostatin receptors; SRIF analogues

Indexed keywords

CGP 23996; CYCLIC AMP; DEXTRO PHENYLALANYLPHENYLALANYLTYROSYL DEXTRO TRYPTOPHYLLYSYLVALYLPHENYLALANYL DEXTRO [3 (2 NAPHTHYL)ALANINAMIDE]; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; PERTUSSIS TOXIN; RADIOLIGAND; SEGLITIDE; SOMATOSTATIN; SOMATOSTATIN RECEPTOR;

ACIDIFICATION; ANIMAL CELL; ARTICLE; CELL CLONE; CONTROLLED STUDY; FIBROBLAST; GENETIC TRANSFECTION; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR AFFINITY; RECEPTOR BINDING;

EID: 0030043712     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15238.x     Document Type: Article

References (34)

1. 2+ mobilization by cloned human somatostatin subtypes 1-5 in transfected COS-7 cells. FEBS Lett., 348, 192-196.
2. BARBER, D.L., MCGUIRE, M.E. & GANZ, M.B. (1989). β-adrenergic and somatostatin receptors regulate Na-H exchange independent of cAMP. J. Biol. Chem., 264, 21038-21042.
3. BUELL, G., SCHULZ, M.F., ARKINSTALL, S.J., MAURY, K., MISSOTTEN, M., ADAMI, N., TALABOT, F. & KAWASHIMA, E. (1992). Molecular characterization, expression and localization of human neurokinin-3 receptor. FEBS Lett., 299, 90-95.
4. CASTRO, S.W., BUELL, G., FENIUK, W. & HUMPHREY, P.P.A. (1994). The expression and characterization of the human SSTR1 and SSTR2 receptors in mouse fibroblast cell lines. Br. J. Pharmacol., 113, 133P.
5. -) cell line. Br. J. Pharmacol., 116, 20P.
6. EPELBAUM, J. (1986). Somatostatin in the nervous system: physiology and pathological modifications. Prog. Neurobiol., 27, 63-100.
7. FENIUK, W., DIMECH, J., JARVIE, E.M. & HUMPHREY, P.P.A. (1995). Further evidence from functional studies for somatostatin receptor heterogeneity in guinea-pig isolated ileum, vas deferens and right atrium. Br. J. Pharmacol., 115, 975-980.
8. HENIKOFF, S. (1984). Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing. Gene, 28, 351-359.
9. HOU, C. GILBERT, R.L. & BARBER, D.L. (1994). Subtype-specific signalling mechanisms of somatostatin receptors SSTR1 and SSTR2. J. Biol. Chem., 269, 10357-10362.
10. HOYER, D., BELL, G.I., BERELOWlTZ, M., EPELBAUM, J., FENIUK, W., HUMPHREY, P.P.A., O'CARROLL, A.M., PATEL, Y.C., SCHONBRUNN, A., TAYLOR, J.E. & REISINE, T. (1995). Classification and nomenclature of somatostatin receptors. Trends Pharmacol. Sci., 16, 86-88.
11. JAKOBS, K.H., AKTORIES, K. & SCHULTZ, G. (1983). A nucleotide regulatory site for somatostatin inhibition of adenylate cyclase in S49 lymphoma cells. Nature, 303, 177-178.
12. KAGIMOTO, S., YAMADA, Y., IHARA, Y., YASUDA, K., KOZASA, T., IMURA, H., SEINO, S. & SEINO, Y. (1994). Human somatostatin receptor, SSTR2, is coupled to adenylyl cyclase in the presence of Giα1 protein. Biochem. Biophys. Res. Commun., 202, 1188-1195.
13. KAUPMANN, K., BRUNS, C., HOYER, D., SEUWEN, K. & LÜBBERT, H. (1993). Distribution and second messenger coupling of four somatostatin receptor subtypes expressed in brain. FEBS Lett., 331, 53-59.
14. KOCH, B.D., DORFLINGER, L.J. & SCHONNBRUNN, A. (1985). Pertussis toxin blocks both cAMP-mediated and cAMP-independent actions of somatostatin. J. Biol. Chem., 260, 13138-13145.
15. LEWIS, D., WEIGHT, F. & LUINI, A. (1986). A guanine nucleotide-binding protein mediating the inhibition of voltage-dependent calcium current by somatostatin in a pituitary cell line. Proc. Natl. Acad. Sci. U.S.A., 83, 9035-9039.
16. LIEBOW, C., REILLY, C., SERRANO, M. & SCHALLY, A. (1989). Somatostatin analogues inhibit growth of pancreatic cancer by stimulating tyrosine phosphatase. Proc. Natl. Acad. Sci. U.S.A., 86, 2003-2008.
17. MCCONNELL, H.M., OWICKI, J.C., PARCE, J.W., MILLER, D.L., BAXTER, G.T., WADA, H.G. & PITCHFORD, S. (1992). The Cytosensor Microphysiometer: Biological applications of silicon technology. Science, 257, 1906-1912.
18. 1 receptors of the contractile action of somatostatin in rat isolated distal colon: studies using some novel SRIF analogues. Br. J. Pharmacol., 113, 628-634.
19. MCPHERSON, G.A. (1985). Analysis of radioligand binding experiments: a collection of computer programmes for the IBM PC. J. Pharmacol. Methods, 14, 213-228.
20. MUNSON, P.J. & RODBARD, D. (1980). LIGAND: a versitile, computerized approach for the characterization of ligand binding systems. Anal. Biochem., 107, 220-239.
21. PAGE, M.J. (1988). Expression of foreign genes in mammalian cells. In Methods in Molecular Biology, Vol. 4: New Nucleic Acid Techniques, ed. Walker, J.M. pp. 380-382. Clifton, New Jersey: Humana Press.
22. PATEL, Y.C., GREENWOOD, M.T., WARSZYNSKA, A., PANETTA, R. & SRIKANT, C.B. (1994). All five cloned human somatostatin receptors (hSSTR1-5) are functionally coupled to adenylyl cyclase. Biochem. Biophys. Res. Commun., 198, 605-612.
23. PATEL, Y.C. & SRIKANT, C.B. (1994). Subtype selectivity of peptide analogues for all five cloned human receptors (hsstr1-5). Endocrinology, 135, 2814-2817.
24. RAYNOR, K., MURPHY, W.A., COY, D.H., TAYLOR, J.E., MOREAU, J.-P., YASUDA, K., BELL, G.I. & REISINE, T. (1993a). Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides. Mol. Pharmacol., 43, 838-844.
25. RAYNOR, K., O'CARROLL, A.M., KONG, H., YASUDA, K., MAHAN, L.C., BELL, G.I. & REISINE, T. (1993b). Characterization of cloned somatostatin receptors SSTR4 and SSTR5. Mol. Pharmacol., 44, 385-392.
26. RAYNOR, K. & REISINE, T. (1989). Analogues of somatostatin selectively label distinct subtypes of somatostatin receptors in rat brain. J. Pharmacol. Exp. Ther., 251, 510-517.
27. RAYNOR, K., WANG, H.L., DICHTER, M. & REISINE, T. (1991). Subtypes of somatostatin receptors couple to multiple cellular effector systems. Mol. Pharmacol., 40, 248-253.
28. REICHLIN, S. (1983). Somatostatin. New Engl. J. Med., 309, 1495-1501, 1556-1563.
29. RENS-DOMIANO, S., LAW, S.F., YAMADA, Y., SEINO, S., BELL, G.I. & REISINE, T. (1992). Pharmacological properties of two cloned somatostatin receptors. Mol. Pharmacol., 42, 28-34.
30. REUBI, J.C. (1984). Evidence for two somatostatin-14 receptor types in rat brain cortex. Neurosci. Lett., 49, 259-263.
31. VIGUERIER, N., TAHIN-JOUTI, N., AYRAL, A.M., CAMBILLAM, C., SCEMAMA, J.L., BASTIÉ, M.J., KRUHTESEN, S., ESTÈIRE, J.P., PRADAYROL, L., SUSINI, C. & VAYSSE, N. (1989). Direct inhibitory effects of a somatostatin analogue, SMS 201-995, on AR4-2J cell proliferation via pertussis toxin-sensitive guanosine triphosphate-binding protein-independent mechanism. Endocrinology, 124, 1017-1025.
32. YAMADA, Y., POST, S.R., WANG, K., TAGER, H.S., BELL, G.I. & SEINO, S. (1992). Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract and kidney. Proc. Natl. Acad. Sci. U.S.A., 89, 251-255.
33. YAMASHITA, N., SHIBUYA, N. & OGATA, E. (1987). Hyperpolarization of the membrane potential caused by somatostatin in dissociated human putuitary adenoma cells that secrete growth hormone. Proc. Natl. Acad. Sci. U.S.A., 83, 6198-6202.
34. YASUDA, K., RENS-DOMIANO, S., BREDER, C.D., LAW, S.F., SAPER, C.B., REISINE, T. & BELL, G.I. (1992). Cloning of a new somatostatin receptor, SSTR3, coupled to adenylyl cyclase. J. Biol. Chem., 267, 20422-20428.