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Volumn 1, Issue 4, 2003, Pages 372-384

Shedding light on health and disease using molecular beacons

Author keywords

Allele discrimination; Disease states; Gene detection; Molecular beacons; PCR; Structure function relationship

Indexed keywords

ANIMAL; GENETIC MARKER; GENETIC PREDISPOSITION; HUMAN; MICROBIOLOGICAL EXAMINATION; POINT MUTATION; POLYMERASE CHAIN REACTION; REVIEW;

EID: 1842479326     PISSN: 14739550     EISSN: 14774062     Source Type: Journal    
DOI: 10.1093/bfgp/1.4.372     Document Type: Article
Times cited : (34)

References (67)
  • 1
    • 0025785461 scopus 로고    scopus 로고
    • Recent advances in the polymerase chain reaction
    • Erlich, H. A., Gelfand, D. and Sninsky, J. J. (1999), 'Recent advances in the polymerase chain reaction', Science, Vol. 252, pp. 1643-1651.
    • (1999) Science , vol.252 , pp. 1643-1651
    • Erlich, H.A.1    Gelfand, D.2    Sninsky, J.J.3
  • 2
    • 0035149083 scopus 로고    scopus 로고
    • A novel strategy for human papillomavirus detection and genotyping with SybrGreen and molecular beacon polymerase chain reaction
    • Szuhai, K., Sandhaus, E., Kolkman-Uljee, S. M. et al. (2001), 'A novel strategy for human papillomavirus detection and genotyping with SybrGreen and molecular beacon polymerase chain reaction', Am. J. Pathol., Vol. 159, pp. 1651-1660.
    • (2001) Am. J. Pathol. , vol.159 , pp. 1651-1660
    • Szuhai, K.1    Sandhaus, E.2    Kolkman-Uljee, S.M.3
  • 3
    • 0029670262 scopus 로고    scopus 로고
    • Molecular beacons: Probes that fluoresce upon hybridization
    • Tyagi, S. and Kramer, F. R. (1996), 'Molecular beacons: probes that fluoresce upon hybridization', Nat. Biotechnol., Vol. 14, pp. 303-308.
    • (1996) Nat. Biotechnol. , vol.14 , pp. 303-308
    • Tyagi, S.1    Kramer, F.R.2
  • 4
    • 0031983834 scopus 로고    scopus 로고
    • Multicolor molecular beacons for allele discrimination
    • Tyagi, S., Bratu, D. P. and Kramer, F. R. (1998), 'Multicolor molecular beacons for allele discrimination', Nat. Biotechnol., Vol. 16, pp. 49-53.
    • (1998) Nat. Biotechnol. , vol.16 , pp. 49-53
    • Tyagi, S.1    Bratu, D.P.2    Kramer, F.R.3
  • 5
    • 0033033430 scopus 로고    scopus 로고
    • Thermodynamic basis of the enhanced specificity of structured DNA probes
    • Bonnet, G., Tyagi, S., Libchaber, A. and Kramer, F. R. (1999), 'Thermodynamic basis of the enhanced specificity of structured DNA probes', Proc. Natl. Acad. Sci. USA, Vol. 96, pp. 6171-6176.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 6171-6176
    • Bonnet, G.1    Tyagi, S.2    Libchaber, A.3    Kramer, F.R.4
  • 6
    • 0036798115 scopus 로고    scopus 로고
    • Structure-function relationships of shared-stem and conventional molecular beacons
    • (in press)
    • Tsourkas, A., Behlke, M. A. and Bao, G. (in press), 'Structure-function relationships of shared-stem and conventional molecular beacons', Nucleic Acids Res., Vol. 30, pp. 4208-4215.
    • Nucleic Acids Res. , vol.30 , pp. 4208-4215
    • Tsourkas, A.1    Behlke, M.A.2    Bao, G.3
  • 7
    • 84873678283 scopus 로고    scopus 로고
    • URL: http://www.bioinfo.math.rpi.edu/~mfold
  • 8
    • 0033764715 scopus 로고    scopus 로고
    • Wavelength-shifting molecular beacons
    • Tyagi, S., Marras, S. A. and Kramer, F. R. (2000), 'Wavelength-shifting molecular beacons', Nat. Biotechnol., Vol. 18, pp. 1191-1196.
    • (2000) Nat. Biotechnol. , vol.18 , pp. 1191-1196
    • Tyagi, S.1    Marras, S.A.2    Kramer, F.R.3
  • 9
    • 0034941396 scopus 로고    scopus 로고
    • Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules
    • Han, M., Gao, X., Su, J. Z. and Nie, S. (2001), 'Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules', Nat. Biotechnol., Vol. 19, pp. 631-635.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 631-635
    • Han, M.1    Gao, X.2    Su, J.Z.3    Nie, S.4
  • 10
    • 0035075442 scopus 로고    scopus 로고
    • Single-mismatch detection using gold-quenched fluorescent oligonucleotides
    • Dubertret, B., Calame, M. and Libchaber, A. J. (2001), 'Single-mismatch detection using gold-quenched fluorescent oligonucleotides', Nat. Biotechnol., Vol. 19, pp. 365-370.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 365-370
    • Dubertret, B.1    Calame, M.2    Libchaber, A.J.3
  • 11
    • 0036835759 scopus 로고    scopus 로고
    • Efficiencies of fluorescence resonance energy transfer and contact-mediated quenching in oligonucleotide probes
    • Marras, S. A., Kramer, F. R. and Tyagi, S. (2002), 'Efficiencies of fluorescence resonance energy transfer and contact-mediated quenching in oligonucleotide probes', Nucleic Acids Res., Vol. 30, pp. E122.
    • (2002) Nucleic Acids Res. , vol.30
    • Marras, S.A.1    Kramer, F.R.2    Tyagi, S.3
  • 12
    • 0033903214 scopus 로고    scopus 로고
    • Rapid identification of Candida duhliniensis using a species-specific molecular beacon
    • Park, S., Wong, M., Marras, S. A. et al. (2000), 'Rapid identification of Candida duhliniensis using a species-specific molecular beacon', J. Clin. Microbiol., Vol. 38, pp. 2829-2836.
    • (2000) J. Clin. Microbiol. , vol.38 , pp. 2829-2836
    • Park, S.1    Wong, M.2    Marras, S.A.3
  • 13
    • 0035310735 scopus 로고    scopus 로고
    • Candida duhliniensis at a cancer center
    • Sebti, A., Kiehn, T. E., Perlin, D. et al. (2001), 'Candida duhliniensis at a cancer center', Clin. Infect. Dis., Vol. 32, pp. 1034-1038.
    • (2001) Clin. Infect. Dis. , vol.32 , pp. 1034-1038
    • Sebti, A.1    Kiehn, T.E.2    Perlin, D.3
  • 14
    • 0035213565 scopus 로고    scopus 로고
    • Nucleic acid sequence-based amplification assays for rapid detection of West Nile and St. Louis encephalitis viruses
    • Lanciotti, R. S. and Kerst, A.J. (2001), 'Nucleic acid sequence-based amplification assays for rapid detection of West Nile and St. Louis encephalitis viruses', J. Clin. Microbiol., Vol. 39, pp. 4506-4513.
    • (2001) J. Clin. Microbiol. , vol.39 , pp. 4506-4513
    • Lanciotti, R.S.1    Kerst, A.J.2
  • 15
    • 0034797943 scopus 로고    scopus 로고
    • Quantitative detection of hepatitis B virus DNA by real-time nucleic acid sequence-based amplification with molecular beacon detection
    • Yates, S., Penning, M., Goudsmit, J. et al. (2001), 'Quantitative detection of hepatitis B virus DNA by real-time nucleic acid sequence-based amplification with molecular beacon detection', J. Clin. Microbiol., Vol. 39, pp. 3656-3665.
    • (2001) J. Clin. Microbiol. , vol.39 , pp. 3656-3665
    • Yates, S.1    Penning, M.2    Goudsmit, J.3
  • 16
    • 0034630153 scopus 로고    scopus 로고
    • Molecular beacons: A real-time polymerase chain reaction assay for detecting Salmonella
    • Chen, W., Martinez, G. and Mulchandani, A. (2000), 'Molecular beacons: a real-time polymerase chain reaction assay for detecting Salmonella, Anal. Biochem., Vol. 280, pp. 166-172.
    • (2000) Anal. Biochem. , vol.280 , pp. 166-172
    • Chen, W.1    Martinez, G.2    Mulchandani, A.3
  • 17
    • 0033669126 scopus 로고    scopus 로고
    • Real-time PCR using molecular beacons for accurate detection of the Y chromosome in single human blastomeres
    • Pierce, K. E., Rice, J. E., Sanchez, J. A., Brenner, C. and Wangh, L.J. (2000), 'Real-time PCR using molecular beacons for accurate detection of the Y chromosome in single human blastomeres', Mol. Hum. Reprod., Vol. 6, pp. 1155-1164.
    • (2000) Mol. Hum. Reprod. , vol.6 , pp. 1155-1164
    • Pierce, K.E.1    Rice, J.E.2    Sanchez, J.A.3    Brenner, C.4    Wangh, L.J.5
  • 18
    • 0032955397 scopus 로고    scopus 로고
    • Differential expression of 10 sigma factor genes in Mycobacterium tuberculosis
    • Manganelli, R., Dubnau, E., Tyagi, S., Kramer, F. R. and Smith, I. (1999), 'Differential expression of 10 sigma factor genes in Mycobacterium tuberculosis', Mol. Microbiol., Vol. 31, pp. 715-724.
    • (1999) Mol. Microbiol. , vol.31 , pp. 715-724
    • Manganelli, R.1    Dubnau, E.2    Tyagi, S.3    Kramer, F.R.4    Smith, I.5
  • 19
    • 1642602496 scopus 로고    scopus 로고
    • Homogeneous scoring of single-nucleotide polymorphisms: Comparison of the 5'-nuclease TaqMan assay and molecular beacon probes
    • Täpp, I., Malmberg, L., Rennel, E., Wik, M. and Syvänen, A. C. (2000), 'Homogeneous scoring of single-nucleotide polymorphisms: comparison of the 5'-nuclease TaqMan assay and molecular beacon probes', Biotechniques, Vol. 28, pp. 732-738.
    • (2000) Biotechniques , vol.28 , pp. 732-738
    • Täpp, I.1    Malmberg, L.2    Rennel, E.3    Wik, M.4    Syvänen, A.C.5
  • 20
    • 0035713577 scopus 로고    scopus 로고
    • Using molecular beacons to detect single-nucleotide polymorphisms with real-time PCR
    • Mhlanga, M. M. and Malmberg, L. (2001), 'Using molecular beacons to detect single-nucleotide polymorphisms with real-time PCR', Methods, Vol. 25, pp. 463-471.
    • (2001) Methods , vol.25 , pp. 463-471
    • Mhlanga, M.M.1    Malmberg, L.2
  • 21
    • 0033038898 scopus 로고    scopus 로고
    • Multiplex detection of four pathogenic retroviruses using molecular beacons
    • Vet, J. A., Majithia, A. R., Marras, S. A. E. et al. (1999), 'Multiplex detection of four pathogenic retroviruses using molecular beacons', Proc. Natl. Acad. Sri. USA, Vol. 96, pp. 6394-6399.
    • (1999) Proc. Natl. Acad. Sri. USA , vol.96 , pp. 6394-6399
    • Vet, J.A.1    Majithia, A.R.2    Marras, S.A.E.3
  • 22
    • 0035158709 scopus 로고    scopus 로고
    • Establishment of new transmissible and drug-sensitive human immunodeficiency virus type 1 wild types due to transmission of nucleoside analogue-resistant virus
    • de Ronde, A., van Dooren, M., van Der Hoek, L. et al. (2001), 'Establishment of new transmissible and drug-sensitive human immunodeficiency virus type 1 wild types due to transmission of nucleoside analogue-resistant virus', J. Virol., Vol. 75, pp. 595-602.
    • (2001) J. Virol. , vol.75 , pp. 595-602
    • De Ronde, A.1    Van Dooren, M.2    Van Der Hoek, L.3
  • 23
    • 0034426098 scopus 로고    scopus 로고
    • Use of molecular beacons to detect an antifolate resistance-associated mutation in Plasmodium falciparum
    • Durand, R., Eslahpazire, J., Jafari, S. et al. (2000), 'Use of molecular beacons to detect an antifolate resistance-associated mutation in Plasmodium falciparum', Antimicrob. Agents Chemother., Vol. 44, pp. 3461-3464.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 3461-3464
    • Durand, R.1    Eslahpazire, J.2    Jafari, S.3
  • 25
    • 0032905227 scopus 로고    scopus 로고
    • Molecular epidemiologic evaluation of transmissibility and virulence of Mycobacterium tuberculosis
    • Rhee, J. T., Piatek, A. S., Small, P. M. et al. (1999), 'Molecular epidemiologic evaluation of transmissibility and virulence of Mycobacterium tuberculosis', J. Clin. Microbiol. Vol. 37, pp. 1764-1770.
    • (1999) J. Clin. Microbiol. , vol.37 , pp. 1764-1770
    • Rhee, J.T.1    Piatek, A.S.2    Small, P.M.3
  • 27
    • 13044263875 scopus 로고    scopus 로고
    • Race-specific HIV-1 disease-modifying effects associated with CCR5 haplotypes
    • Gonzalez, E., Bamshad, M., Sato, N. et al. (1999), 'Race-specific HIV-1 disease-modifying effects associated with CCR5 haplotypes', Proc. Natl. Acad. Sri. USA, Vol. 96, pp. 12004-12009.
    • (1999) Proc. Natl. Acad. Sri. USA , vol.96 , pp. 12004-12009
    • Gonzalez, E.1    Bamshad, M.2    Sato, N.3
  • 29
    • 0035110871 scopus 로고    scopus 로고
    • Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis
    • Shih, I. M., Zhou, W., Goodman, S. N., Lengauer, C., Kinzler, K. W. and Vogelstein, B. (2001), 'Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis', Cancer Res., Vol. 61, pp. 818-822.
    • (2001) Cancer Res. , vol.61 , pp. 818-822
    • Shih, I.M.1    Zhou, W.2    Goodman, S.N.3    Lengauer, C.4    Kinzler, K.W.5    Vogelstein, B.6
  • 30
    • 0035258312 scopus 로고    scopus 로고
    • Simultaneous A8344G heteroplasmy and mitochondrial DNA copy number quantification in myoclonus epilepsy and ragged-red fibers (MERRF) syndrome by a multiplex molecular beacon based real-time fluorescence PCR
    • Szuhai, K., Ouweland, J. M., Dirks, R. W. et al. (2001), 'Simultaneous A8344G heteroplasmy and mitochondrial DNA copy number quantification in myoclonus epilepsy and ragged-red fibers (MERRF) syndrome by a multiplex molecular beacon based real-time fluorescence PCR', Nucleic Acids Res., Vol. 29, p. E13.
    • (2001) Nucleic Acids Res. , vol.29
    • Szuhai, K.1    Ouweland, J.M.2    Dirks, R.W.3
  • 31
    • 0035865322 scopus 로고    scopus 로고
    • A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms
    • Sachidanandam, R., Weissman, D., Schmidt, S. C. et al. (2001), 'A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms', Nature, Vol. 409, pp. 928-933.
    • (2001) Nature , vol.409 , pp. 928-933
    • Sachidanandam, R.1    Weissman, D.2    Schmidt, S.C.3
  • 32
    • 0345129990 scopus 로고    scopus 로고
    • Multiplex detection of single-nucleotide variations using molecular beacons
    • Marras, S. A., Kramer, F. R. and Tyagi, S. (1999), 'Multiplex detection of single-nucleotide variations using molecular beacons', Genet. Anal., Vol. 14, pp. 151-156.
    • (1999) Genet. Anal. , vol.14 , pp. 151-156
    • Marras, S.A.1    Kramer, F.R.2    Tyagi, S.3
  • 33
    • 0035009916 scopus 로고    scopus 로고
    • One-tube real-time isothermal amplification assay to identify and distinguish human immunodeficiency virus type 1 subtypes A, B, and C and circulating recombinant forms AE and AG
    • de Baar, M. P., Timmermans, E. C., Bakker, M., de Rooij, E., van Genien, B. and Goudsmit, J. (2001), 'One-tube real-time isothermal amplification assay to identify and distinguish human immunodeficiency virus type 1 subtypes A, B, and C and circulating recombinant forms AE and AG', J. Clin. Microbiol., Vol. 39, pp. 1895-1902.
    • (2001) J. Clin. Microbiol. , vol.39 , pp. 1895-1902
    • De Baar, M.P.1    Timmermans, E.C.2    Bakker, M.3    De Rooij, E.4    Van Genien, B.5    Goudsmit, J.6
  • 34
    • 0031969531 scopus 로고    scopus 로고
    • Molecular beacon sequence analysis for detecting drug resistance in Mycobacterium tuberculosis
    • Piatek, A. S., Tyagi, S., Pol, A. C. et al. (1998), 'Molecular beacon sequence analysis for detecting drug resistance in Mycobacterium tuberculosis', Nat. Biotechnol., Vol. 16, pp. 359-363.
    • (1998) Nat. Biotechnol. , vol.16 , pp. 359-363
    • Piatek, A.S.1    Tyagi, S.2    Pol, A.C.3
  • 35
    • 0033989548 scopus 로고    scopus 로고
    • Genotypic analysis of Mycobacterium tuberculosis in two distinct populations using molecular beacons: Implications for rapid susceptibility testing
    • Piatek, A. S., Telenti, A., Murray, M. R. et al. (2000), 'Genotypic analysis of Mycobacterium tuberculosis in two distinct populations using molecular beacons: implications for rapid susceptibility testing', Antimicrob. Agents Chemother., Vol. 44, pp. 103-110.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 103-110
    • Piatek, A.S.1    Telenti, A.2    Murray, M.R.3
  • 36
    • 0034765587 scopus 로고    scopus 로고
    • Detection of rifampin resistance in Mycobacterium tuberculosis in a single tube with molecular beacons
    • El-Hajj, H. H., Marras, S. A., Tyagi, S., Kramer, F. R. and Alland, D. (2001), 'Detection of rifampin resistance in Mycobacterium tuberculosis in a single tube with molecular beacons', J. Clin. Microbiol., Vol. 39, pp. 4131-4137.
    • (2001) J. Clin. Microbiol. , vol.39 , pp. 4131-4137
    • El-Hajj, H.H.1    Marras, S.A.2    Tyagi, S.3    Kramer, F.R.4    Alland, D.5
  • 37
    • 0035654137 scopus 로고    scopus 로고
    • Accessing genetic-variation: Genotyping single nucleotide polymorphisms
    • Syvanen, A. C. (2001), 'Accessing genetic-variation: genotyping single nucleotide polymorphisms', Nature Rev. Genet., Vol. 2, pp. 930-942.
    • (2001) Nature Rev. Genet. , vol.2 , pp. 930-942
    • Syvanen, A.C.1
  • 38
    • 0035553631 scopus 로고    scopus 로고
    • High throughput genotyping technologies for pharmacogenomics
    • Brennan, M. D. (2001), 'High throughput genotyping technologies for pharmacogenomics', Am. J. Pharmacogenomics, Vol. 1, pp. 295-302.
    • (2001) Am. J. Pharmacogenomics , vol.1 , pp. 295-302
    • Brennan, M.D.1
  • 39
    • 0346449444 scopus 로고    scopus 로고
    • SNP genotyping on pooled DNAs; comparison of genotyping technologies and a semiautomated method for data storage and analysis
    • Le Hellard, S., Ballereau, S. J., Visscher, P. M. et al. (2002), 'SNP genotyping on pooled DNAs; comparison of genotyping technologies and a semiautomated method for data storage and analysis', Nucleic Acids Res., Vol. 30, p. e74.
    • (2002) Nucleic Acids Res. , vol.30
    • Le Hellard, S.1    Ballereau, S.J.2    Visscher, P.M.3
  • 40
    • 0032578455 scopus 로고    scopus 로고
    • Real time detection of DNA/ RNA hybridization in living cells
    • Sokol, D. L., Zhang, X., Lu, P. and Gewirtz, A. M. (1998), 'Real time detection of DNA/ RNA hybridization in living cells', Proc Natl. Acad. Sci. USA, Vol. 95, pp. 11538-11543.
    • (1998) Proc Natl. Acad. Sci. USA , vol.95 , pp. 11538-11543
    • Sokol, D.L.1    Zhang, X.2    Lu, P.3    Gewirtz, A.M.4
  • 41
    • 0032472777 scopus 로고    scopus 로고
    • In situ visualization of messenger RNA for basic fibroblast growth factor in living cells
    • Matsuo, T. (1998), 'In situ visualization of messenger RNA for basic fibroblast growth factor in living cells', Biochim. Biophys. Acta, Vol. 1379, pp. 178-184.
    • (1998) Biochim. Biophys. Acta , vol.1379 , pp. 178-184
    • Matsuo, T.1
  • 42
    • 0035891415 scopus 로고    scopus 로고
    • Real-time monitoring of intracellular mRNA hybridization inside single living cells
    • Perlette, J. and Tan, W. (2001), 'Real-time monitoring of intracellular mRNA hybridization inside single living cells', Anal. Chcm., Vol. 73, pp. 5544-5550.
    • (2001) Anal. Chcm. , vol.73 , pp. 5544-5550
    • Perlette, J.1    Tan, W.2
  • 43
    • 0035106632 scopus 로고    scopus 로고
    • Methods for visualizing RNA processing and transport pathways in living cells
    • Dirks, R.W., Molenaar, C. and Tanke, H.J. (2001), 'Methods for visualizing RNA processing and transport pathways in living cells', Histochem. Cell Biol., Vol. 115, pp. 3-11.
    • (2001) Histochem. Cell Biol. , vol.115 , pp. 3-11
    • Dirks, R.W.1    Molenaar, C.2    Tanke, H.J.3
  • 44
    • 0002726408 scopus 로고    scopus 로고
    • Linear 2' O-methyl RNA probes for the visualization of RNA in living cells
    • Molenaar, C., Marras, S. A., Slats, J. C. et al. (2001), 'Linear 2' O-methyl RNA probes for the visualization of RNA in living cells', Nucleic Acids Res., Vol. 29, pp. E89-89.
    • (2001) Nucleic Acids Res. , vol.29
    • Molenaar, C.1    Marras, S.A.2    Slats, J.C.3
  • 45
    • 4644252101 scopus 로고    scopus 로고
    • Using molecular beacons as a sensitive fluorescence assay for enzymatic cleavage of single-stranded DNA
    • Li, J.J., Geyer, R. and Tan, W. (2000), 'Using molecular beacons as a sensitive fluorescence assay for enzymatic cleavage of single-stranded DNA', Nucleic Acids Res., Vol. 28, p. E52.
    • (2000) Nucleic Acids Res. , vol.28
    • Li, J.J.1    Geyer, R.2    Tan, W.3
  • 46
    • 0001380278 scopus 로고    scopus 로고
    • Using molecular beacons to probe molecular interactions between lactate dehydrogenase and single-stranded DNA
    • Fang, X., Li, J. J. and Tan, W. (2000), 'Using molecular beacons to probe molecular interactions between lactate dehydrogenase and single-stranded DNA', Anal. Chem., Vol. 72, pp. 3280-3285.
    • (2000) Anal. Chem. , vol.72 , pp. 3280-3285
    • Fang, X.1    Li, J.J.2    Tan, W.3
  • 47
    • 0000706201 scopus 로고    scopus 로고
    • Detection of nucleic acid hybridization by nonradiative fluorescence resonance energy transfer
    • Cardullo, R. A., Agrawal, S., Flores, C., Zamecnik, P. C. and Wolf, D. E. (1998), 'Detection of nucleic acid hybridization by nonradiative fluorescence resonance energy transfer', Proc. Natl. Acad. Sci. USA., Vol. 85, pp. 8790-8794.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8790-8794
    • Cardullo, R.A.1    Agrawal, S.2    Flores, C.3    Zamecnik, P.C.4    Wolf, D.E.5
  • 48
    • 0027181381 scopus 로고
    • Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells
    • Fisher, T. L., Terhorst, T., Cao, X. and Wagner, R. W. (1993), 'Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells', Nucleic Acids Res., Vol. 21, pp. 3857-3865.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 3857-3865
    • Fisher, T.L.1    Terhorst, T.2    Cao, X.3    Wagner, R.W.4
  • 49
    • 0036885130 scopus 로고    scopus 로고
    • Hybridization of 2'-0-methyl and 2'-deoxy molecular beacons to RNA and DNA targets
    • (in press)
    • Tsourkas, A., Behlke, M. A. and Bao, G. (in press), 'Hybridization of 2'-0-methyl and 2'-deoxy molecular beacons to RNA and DNA targets', Nucleic Acids Res., Vol. 30.
    • Nucleic Acids Res. , vol.30
    • Tsourkas, A.1    Behlke, M.A.2    Bao, G.3
  • 50
    • 0035962892 scopus 로고    scopus 로고
    • A critical survey of the structure-function of the antisense oligo/ RNA heteroduplex as substrate for RNase H
    • Zamaratski, E., Pradeepkumar, P. I. and Chattopadhyaya, J. (2001), 'A critical survey of the structure-function of the antisense oligo/ RNA heteroduplex as substrate for RNase H', J. Biochem. Biophys. Methods, Vol. 48, pp. 189-208.
    • (2001) J. Biochem. Biophys. Methods , vol.48 , pp. 189-208
    • Zamaratski, E.1    Pradeepkumar, P.I.2    Chattopadhyaya, J.3
  • 51
    • 0030909609 scopus 로고    scopus 로고
    • Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: In vitro and in vivo studies
    • Agrawal, S., Jiang, Z., Zhao, Q. et al. (1997), 'Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: in vitro and in vivo studies', Proc. Natl. Acad. Sci. USA, Vol. 94, pp. 2620-2625.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2620-2625
    • Agrawal, S.1    Jiang, Z.2    Zhao, Q.3
  • 52
    • 0029943679 scopus 로고    scopus 로고
    • Phosphorothioate antisense oligodeoxynucleotides: Questions of specificity
    • Stein, C. A. (1996), 'Phosphorothioate antisense oligodeoxynucleotides: questions of specificity', Trends Biotechnol., Vol. 14, pp. 147-149.
    • (1996) Trends Biotechnol. , vol.14 , pp. 147-149
    • Stein, C.A.1
  • 53
    • 0030769388 scopus 로고    scopus 로고
    • CD, absorption and thermodynamic analysis of repeating dinucleotide DNA, RNA and hybrid duplexes [d/r(AC)]12.[d/r(GT/U)]12 and the influence of phosphorothioate substitution
    • Clark, C. L., Cecil, P. K., Singh, D. and Gray, D. M. (1997), 'CD, absorption and thermodynamic analysis of repeating dinucleotide DNA, RNA and hybrid duplexes [d/r(AC)]12.[d/r(GT/U)]12 and the influence of phosphorothioate substitution', Nucleic Acids Res., Vol. 25, pp. 4098-4105.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 4098-4105
    • Clark, C.L.1    Cecil, P.K.2    Singh, D.3    Gray, D.M.4
  • 54
    • 0033565622 scopus 로고    scopus 로고
    • Interaction of chemically modified antisense oligonucleotides with sense DNA: A label-free interaction study with reflectometric interference spectroscopy
    • Sauer, M., Brecht, A., Charisse, K. et al. (1999), 'Interaction of chemically modified antisense oligonucleotides with sense DNA: a label-free interaction study with reflectometric interference spectroscopy', Anal. Cliem., Vol. 71, pp. 2850-2857.
    • (1999) Anal. Cliem. , vol.71 , pp. 2850-2857
    • Sauer, M.1    Brecht, A.2    Charisse, K.3
  • 55
    • 0342618762 scopus 로고    scopus 로고
    • Kinetics for hybridization of peptide nucleic acids (PNA) with DNA and RNA studied with the BIAcore technique
    • Jensen, K. K., Orum, H., Nielsen P. E. and Norden, B. (1997), 'Kinetics for hybridization of peptide nucleic acids (PNA) with DNA and RNA studied with the BIAcore technique', Biochemistry, Vol. 36, pp. 5072-5077.
    • (1997) Biochemistry , vol.36 , pp. 5072-5077
    • Jensen, K.K.1    Orum, H.2    Nielsen, P.E.3    Norden, B.4
  • 56
    • 0034776753 scopus 로고    scopus 로고
    • Investigating the kinetics of DNA-DNA and PNA-DNA interactions using surface plasmon resonance-enhanced fluorescence spectroscopy
    • Kambhampati, D., Nielsen, P. E. and Knoll, W. (2001), 'Investigating the kinetics of DNA-DNA and PNA-DNA interactions using surface plasmon resonance-enhanced fluorescence spectroscopy', Biosens. Bioelectron., Vol. 16, pp. 1109-1118.
    • (2001) Biosens. Bioelectron. , vol.16 , pp. 1109-1118
    • Kambhampati, D.1    Nielsen, P.E.2    Knoll, W.3
  • 57
    • 0032168909 scopus 로고    scopus 로고
    • Hybridization of peptide nucleic acid
    • Ratilainen, T., Holmen, A., Tuite, E. et al. (1998), 'Hybridization of peptide nucleic acid, Biochemistry, Vol. 37, pp. 12331-12342.
    • (1998) Biochemistry , vol.37 , pp. 12331-12342
    • Ratilainen, T.1    Holmen, A.2    Tuite, E.3
  • 58
    • 0035830450 scopus 로고    scopus 로고
    • Inhibition of gene expression inside cells by peptide nucleic acids: Effect of mRNA target sequence, mismatched bases, and PNA length
    • Doyle, D. F., Braasch, D. A., Simmons, C. G., Janowski, B. A. and Corey, D. R. (2001), 'Inhibition of gene expression inside cells by peptide nucleic acids: effect of mRNA target sequence, mismatched bases, and PNA length, Biochemistry, Vol. 40, pp. 53-64.
    • (2001) Biochemistry , vol.40 , pp. 53-64
    • Doyle, D.F.1    Braasch, D.A.2    Simmons, C.G.3    Janowski, B.A.4    Corey, D.R.5
  • 59
    • 0034811832 scopus 로고    scopus 로고
    • Hybridization between oxy-peptide nucleic acids and DNAs: Dependence of hybrid stabilities on the chain-lengths, types of base pairs, and the chain directions
    • Kuwahara, M., Arimitsu, M., Shigeyasu, M., Saeki, N. and Sisido, M. (2001), 'Hybridization between oxy-peptide nucleic acids and DNAs: dependence of hybrid stabilities on the chain-lengths, types of base pairs, and the chain directions', J. Am. Chem. Soc., Vol. 123, pp. 4653-4658.
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 4653-4658
    • Kuwahara, M.1    Arimitsu, M.2    Shigeyasu, M.3    Saeki, N.4    Sisido, M.5
  • 60
    • 0032143301 scopus 로고    scopus 로고
    • PNA molecular beacons for rapid detection of PCR amplicons
    • Ortiz, E., Estrada, G. and Lizardi, P. M. (1998), 'PNA molecular beacons for rapid detection of PCR amplicons', Mol. Cell Probes, Vol. 12, pp. 219-226.
    • (1998) Mol. Cell Probes , vol.12 , pp. 219-226
    • Ortiz, E.1    Estrada, G.2    Lizardi, P.M.3
  • 61
    • 0033620449 scopus 로고    scopus 로고
    • Designing a novel molecular beacon for surface-immobilized UNA hybridization studies
    • Fang, X., Liu, X., Schuster S. and Tan, W. (1999), 'Designing a novel molecular beacon for surface-immobilized UNA hybridization studies', J. Am. Chem. Soc., Vol. 121, pp. 2921-2922.
    • (1999) J. Am. Chem. Soc. , vol.121 , pp. 2921-2922
    • Fang, X.1    Liu, X.2    Schuster, S.3    Tan, W.4
  • 62
    • 0033988142 scopus 로고    scopus 로고
    • Screening unlabeled DNA targets with randomly ordered fiber-optic gene arrays
    • Steemers, F. J., Ferguson, J. A. and Walt, D. R. (2000), 'Screening unlabeled DNA targets with randomly ordered fiber-optic gene arrays', Nat. Biotechnol., Vol. 18, pp. 91-94.
    • (2000) Nat. Biotechnol. , vol.18 , pp. 91-94
    • Steemers, F.J.1    Ferguson, J.A.2    Walt, D.R.3
  • 63
    • 0032754283 scopus 로고    scopus 로고
    • A fiber-optic evanescent wave DNA biosensor based on novel molecular beacons
    • Liu, X. and Tan, W. (1999), 'A fiber-optic evanescent wave DNA biosensor based on novel molecular beacons', Anal. Chem., Vol. 71, pp. 5054-5059.
    • (1999) Anal. Chem. , vol.71 , pp. 5054-5059
    • Liu, X.1    Tan, W.2
  • 64
    • 0034661972 scopus 로고    scopus 로고
    • Molecular beacons for DNA biosensors with micrometer to submicrometer dimensions
    • Liu, X., Farmerie, W., Schuster, S. and Tan, W. (2000), 'Molecular beacons for DNA biosensors with micrometer to submicrometer dimensions', Anal. Biochem., Vol. 283, pp. 56-63.
    • (2000) Anal. Biochem. , vol.283 , pp. 56-63
    • Liu, X.1    Farmerie, W.2    Schuster, S.3    Tan, W.4
  • 65
    • 0037065663 scopus 로고    scopus 로고
    • Hybridization of DNA and PNA molecular beacons to single-stranded and double-stranded DNA targets
    • Kuhn, H., Demidov, V. V., Coull, J. M., Fiandaca, M. J., Gildea, B. D. and Frank-Kamenetskii, M. D. (2002), 'Hybridization of DNA and PNA molecular beacons to single-stranded and double-stranded DNA targets', J. Am. Chem. Soc., Vol. 124, pp. 1097-1103.
    • (2002) J. Am. Chem. Soc. , vol.124 , pp. 1097-1103
    • Kuhn, H.1    Demidov, V.V.2    Coull, J.M.3    Fiandaca, M.J.4    Gildea, B.D.5    Frank-Kamenetskii, M.D.6
  • 66
    • 0035879386 scopus 로고    scopus 로고
    • Aptamer beacons for the direct detection of proteins
    • Hamaguchi, N., Ellington, A. and Stanton, M. (2001), 'Aptamer beacons for the direct detection of proteins', Anal. Biochem., Vol. 294, pp. 126-131.
    • (2001) Anal. Biochem. , vol.294 , pp. 126-131
    • Hamaguchi, N.1    Ellington, A.2    Stanton, M.3
  • 67
    • 0034086583 scopus 로고    scopus 로고
    • Molecular beacon aptamer fluoresces in the presence of Tat protein of HIV-1
    • Yamamoto, R., Baba, T. and Kumar, P. K. (2000), 'Molecular beacon aptamer fluoresces in the presence of Tat protein of HIV-1', Genes Cells, Vol. 5, pp. 389-396.
    • (2000) Genes Cells , vol.5 , pp. 389-396
    • Yamamoto, R.1    Baba, T.2    Kumar, P.K.3


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